Anatolia Tani ve Biyoteknoloji A.S

Bosphore Thrombophilia Panel Kits are multiplex kits for detection of FVL, FII (Prothrombin), MTHFR C677T and MTHFR A1298C simultaneously.  

Fast extraction version of the kit enables the users to get the results in less than 2 hours including genomic DNA extraction, a solution which is both cost effective and time saving. The users do not need to use DNA extraction kits. Fast extraction reagent is already included in the kit content.

Bosphore Genetic Mutation Tests use probe based PCR technology. Therefore Bosphore kits are superior to market competitors in terms of specificity. Mutations and polymorphisms are detected accurately by sequence specific probes. 

Anatolia Geneworks, with its continuously expanding genetic diseases panel, and kits designed according to clinical and laboratory practice needs, and that are compatible with barcode controlled workflow and sample tracking, present you a highly quality diagnostic system.

Magnesia® 2448 Extraction and PCR Setup System

DNA extraction and PCR preparation systems are designed to precisely process all steps required for these complex and time consuming applications on an automated platform. Sample pipetting, reagent dispensing, magnetic particle pipetting, separation and washing and the final transfer of the obtained DNA to the PCR tubes are performed in an environment protected from contamination.

Based on our proven sample processing technology, the Magnesia 2448 Nucleic Acid Extraction & PCR Set-up equipment was designed to increase safety and throughput of complex and time consuming preparation of DNA amplification procedures. The system incorporates a high precision 4-channel pipetting system with disposable tips for transfer and mixing of samples and reagents capable of piercing sealed microplates, microplate shaker/incubators to accommodate standard and deep well microplates and cooling modules for PCR tubes and reagent containers.

With its robust and open design, Magnesia is the starting point for various applications. All patented; specially designed incubators, magnetic racks, shakers, reagent carriers and active cooling racks share the SBS standards for easy reagent and sample plate transfer. Empty channels between the modules eliminate the risk of contamination. Different types of sample tubes, thanks to individually controlled pipettes and liquid level detection system.

Predefined travel routes keep the pipette head away from the samples and reagents, while carrying a used pipette tip. UV lamps are strong enough to provide sufficient UV decontamination of the worktable in just 15 minutes. The tip and plate carrier modules are removable on their rails, and stainless steel worktable can be easily cleaned, if needed.

Barcode readers, pre-filled and sealed reagents, liquid level and pipette tip detectors, pressure sensors prevent any user-induced errors and ensure the operational reliability. Actively cooled 3 separate closed chambers keep the agents, eluted nucleic acids and PCR plates as 2-4 degrees during the whole process. Excess DNA/RNA that is not used during the PCR setup is stored in barcoded plates to be identified and used in the future assays. The discharged tips are disinfected to keep the disposal box free of contamination.

Anatolia Geneworks® high quality IVD-CE marked Bosphore® Real-Time PCR kits have the highest sensitivity of the world, up to 3,6 IU/ml for HBV quantification and 8 IU/ml for HCV quantification with IVD–CE lot verification warranty.
Anatolia's reason of existence is developing and producing appropriately certified, excellent products for outstanding healthcare with affordable costs. Please visit our website to see our wide range of Real-Time PCR kits for pathogen detection for more than 200 parameters including Hepatitis (HBV, HCV, HDV), Herpes family (CMV, EBV, HHV-3, HHV-6, HHV-7, HHV-8, HSV 1-2), JCV, BKV, Parvovirus B19, HIV-1, Chlamydia trachomatis.

Bosphore & Bosphore Ultra HCV Real-Time PCR Kits
Superior sensitivity up to 8 IU/ml
Detect and quantitate Hepatitis C virus (HCV) RNA, encompassing all HCV genotypes including HCV 1-8
Up to 5 quantitation standards that undergo RNA extraction
IVD CE Mark according to the Directive 98/79/EC
Internal control through extraction and Real-Time PCR
Calibration against WHO International Standard for HCV RNA NAT assays

Bosphore HDV Quantification-Detection Kit v1
Superior sensitivity of 45 copies/ml
Kits detect and quantitate the Hepatitis D (HDV) Virus RNA in human plasma or serum, encompassing all HDV genotypes (1-8).
Four quantitation standards
IVD CE Mark according to the Directive 98/79/EC
Internal control through extraction and Real-Time PCR
Calibration against WHO International Standard for HDV RNA NAT assays

Bosphore & Bosphore Ultra HBV Real-Time PCR Kits
Superior sensitivity up to 3.6 IU/ml
Detect and quantitate Hepatitis B virus (HBV) DNA, encompassing all the HBV genotypes
Up to 5 quantitation standards that undergo DNA extraction
IVD-CE Mark according to the Directive 98/79/EC
Internal control through extraction and Real-Time PCR
Calibration against WHO International Standard for HBV DNA NAT assays

Bosphore & Bosphore Ultra HIV-1 Real-Time PCR Kits
Superior sensitivity up to 19 IU/ml
detect and quantitate Human Immunodeficiency Virus RNA, encompassing all the HIV-1 subtypes
Up to 5 quantitation standards that undergo RNA extraction
IVD CE Marking according to the Directive 98/79/EC
Internal control through extraction and Real-Time PCR, UNG option
Calibration against WHO International Standard for HIV-1 RNA NAT assays

Bosphore Multiplex Real-Time PCR Panel Kits are raising the standards in infectious disease testing.

Bosphore Respiratory Pathogens Panel Kits
Multiplex panel kits in different combinations for 33 parameters in up to 11 master mixes.

Anatolia Geneworks Panel Kit Solutions for multiplex detection of respiratory pathogens provide high specificity and sensitivity in shorter processing time compared to diagnosis by culture or rapid tests.

Bosphore STDs Panel Kits
Multiplex panel kits in different combinations for 11 parameters in up to 5 master mixes:
Chlamydia trachomatis, Ureaplasma urealyticum, Ureaplasma parvum, Mycoplasma hominis, Neisseria gonorrhea, Trichomonas vaginalis, Gardnerella vaginalis, Mycoplasma genitalium, Treponema pallidum, HSV-1 and HSV-2

Anatolia Geneworks Panel Kit Solutions for multiplex detection of sexually transmitted diseases (STDs), provide specificity, high sensitivity, and a short turnaround time where early detection plays a key role in successful treatment and containment strategies.

Bosphore Meningitis Panel Kits (Bacterial, Viral, Neonatal)
Bacterial Meningitis Panel: Haemophilus influenzae, Neisseria meningitidis, Streptococcus pneumoniae
Neonatal Meningitis Panel:  Escherichia coli, Listeria monocytogenes, Streptococcus group B, Streptococcus pneumoniae
Viral Meningitis Panel: Enterovirus, HSV-1, HSV-2 , Parechovirus, VZV

Anatolia Geneworks Panel Kit Solutions for multiplex detection of meningitis pathogens, help medical professionals with diagnosis at an early stage to prevent mortality and long-term neural disabilities.

Bosphore CNS Panel Kits
Multiplex panel kits in different combinations for 11 parameters in up to 4 master mixes:
Adenovirus, Enterovirus, Parechovirus, Parvovirus B19, CMV, EBV, HHV-6, HHV-7, HSV-1, HSV-2, VZV.

Anatolia Geneworks Panel Kits provide a highly specific, sensitive solution for simultaneously detecting a wide range of DNA and RNA viruses causing neurological infections.

Bosphore Atypical CAP Panel Kit
Multiplex panel kit for 3 parameters in 1 master mix: 
Chlamydophila pneumoniae, Legionella pneumophila/longbeachae, Mycoplasma pneumoniae

Bosphore Viral Infections in the Immunosuppressed Panel Kits
Multiplex panel kits in different combinations for 5 parameters in up to 2 master mixes:
Adenovirus, BKV, CMV, EBV, JCV

Bosphore Vesicular Rash Panel Kit
Multiplex panel kit for 3 parameters in 1 master mix: 
HSV-1, HSV-2, VZV

Bosphore Eye Infection Panel Kits
Multiplex panel kits in different combinations for 7 parameters in up to 3 master mixes:
Adenovirus, Chlamydia trachomatis, CMV,  EBV, HSV-1,  HSV-2, VZV