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Image: Man holding stretched 3D-printed material with purple gloves; Copyright: Casey Cass/CU Boulder

Casey Cass/CU Boulder

3D printed custom implants for the heart

05.09.2024

Researchers at the University of Colorado Boulder, in collaboration with the University of Pennsylvania, have developed an advanced 3D printing method to create materials that support human tissue effectively. This new approach could lead to significant improvements in personalized medical implants and tissue repair.
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Image: A person in a white coat explains the human heart with the help of an anatomical model. The model shows the inner structure of the heart in detail.

From permanent to resorbable: self-dissolving stents as heart implants

02.08.2024

Cardiology is increasingly transitioning from traditional metal stents to self-dissolving stents for the treatment of coronary heart disease. These new magnesium stents have the potential to improve the treatment and outcomes for a large patient population.
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Image: Illustration of a knee with the synthetic plug to treat pain; Copyright: Texas A&M Engineering

Texas A&M Engineering

Synthetic plugs offer an alternative to total knee replacements

05.06.2024

Dr. Melissa Grunlan, a professor in the Department of Biomedical Engineering at Texas A&M University, is developing synthetic plugs to treat chronic knee pain and disabilities, offering an alternative to total knee replacements. This project is funded by the National Institute of Arthritis and Musculoskeletal and Skin Diseases, a part of the National Institutes of Health.
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Image: Man holding the new absorbable stent close to the camera; Copyright: Karin Kaiser/MHH

Karin Kaiser/MHH

Advancements in Cardiac Treatment: MHH's Deployment of Self-Dissolving Stents

31.05.2024

At the forefront of cardiac care, the Department of Cardiology and Angiology at Hannover Medical School (MHH) has introduced a novel treatment method using self-dissolving stents.
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Image: Elderly man with glasses and light green top holds his hand to his aching neck

Neurostimulation: Inceptiv™ fighting chronic neuropathic pain

19.04.2024

Neurostimulators play an important role in the treatment of chronic pain conditions. They use targeted electrical impulses to modulate pain signals. The Inceptiv™ neurostimulator from Medtronic is an example of a treatment solution for chronic neuropathic pain. It can offer sufferers a significant improvement in their quality of life.
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Image: A researcher in a lab is carefully operating a 3D bioprinting machine that is used for creating bioengineered tissues; Copyright: Michelle Bixby/Penn State

Michelle Bixby/Penn State

3D-printed skin technique potentially enhances reconstructive surgery

15.04.2024

A breakthrough in reconstructive surgery may be on the horizon, as researchers develop a 3D-printed skin that integrates hair follicle precursors, leveraging adipose tissue for more natural results.
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Image: Close-up of the surgeon's hands during an operation

Wound closure: soldering with light and nanotechnology

02.04.2024

With "iSoldering", the Particles Biology Interactions Laboratory at the Swiss Federal Laboratories for Materials Science and Technology (Empa) in St. Gallen and the Nanoparticle Systems Engineering Laboratory at ETH Zurich have developed a method that does not require surgical sutures or synthetic adhesives. Instead, nanoparticles and light enable secure wound closure.
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Image: A stained micrograph of 3D primary human liver cell tissue modeling MASH. Areas of fibrosis are indicated in blue; Copyright: Viscient Biosciences

Viscient Biosciences

Revolutionizing liver disease research with 3D bioprinted model

07.02.2024

Metabolic dysfunction-associated steatohepatitis (MASH), previously known as nonalcoholic steatohepatitis (NASH), is a liver disease characterized by inflammation and scarring, reaching epidemic proportions with an estimated 1.5 percent to 6.5 percent of U.S. adults affected.
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Image: Two women looking at a display of cells on a monitor; Copyright: University of Jyväskylä

University of Jyväskylä

Antiviral resin destroys COVID-19 from plastic surfaces

06.02.2024

Researchers at the University of Jyväskylä in Finland are pioneering the development of antiviral surfaces to mitigate the spread of infectious diseases, particularly focusing on coronaviruses.
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Image: Robotically controlled rotating magnetic field to control the millirobot wirelessly through an aorta and kidney; Copyright: University of Twente

University of Twente

Miniature marvels: wireless millirobots successfully navigate arteries

18.12.2023

For the first time ever, wireless millirobots navigated a narrow blood vessel both along and against arterial flow. Researchers from the University of Twente and Radboudumc inserted the screw-shaped robots in a detached aorta with kidneys where they controlled them using a robotically controlled rotating magnet.
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Image: An artist’s impression of a GELECTO machine interacting with biological cells via sending and reading of electrical and biochemical signals; Copyright: Leibniz-IPF, Ivan Minev

Leibniz-IPF, Ivan Minev

New era of cyborganics – Prof. Ivan Minev receives ERC Consolidator Grant

30.11.2023

Over the next five years, the ERC will provide two million euro of funding for the development of a new class of electronic components that consist almost entirely of water and could make the interface between biological tissue and machine seamless.
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A woman with a microphone interviews a man in a suit at a trade fair stand; copyright: beta-web | Messe Düsseldorf

Smartly crafting medical adhesives – Avery Dennison

15.11.2023

Avery Dennison, a global powerhouse in materials science, is advancing the field of medical adhesives, both for wound and surgical care as well as for wearables. With a multidisciplinary team and a dedication to addressing current industry challenges, they deliver solutions that not only meet the practical needs of medical applications but also enhance the comfort for patients.
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Image: At the pilot plant, a 3D printer builds the scaffold from the composite material; Copyright: BellaSeno

BellaSeno

Bioactive composite supports healing of broken bones

09.11.2023

A broken bone failing to heal represents an enormous burden for patients. Fraunhofer researchers have worked alongside partners to develop a composite material to be used in the treatment of such non-union cases. The resulting implant is designed to significantly improve treatment success rates and speed up the healing process.
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Image: light brown bone screw Shark Screw; Copyright: DIZG

DIZG

Faster return to health with bone screws made from donated tissue

16.10.2023

During fracture treatment, screws are frequently used to join bone fragments. Traditional metal screws can necessitate additional surgeries during follow-up treatment, extending the healing process. Shark Screw® bone screw, crafted from human tissue, presents significant benefits in this context.
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Image: A bald man in a white coat stands in a laboratory and looks over at other people; Copyright: Joakim Palmqvist

Joakim Palmqvist

Advanced biosensors to detect tumors, viruses and bacterial diseases

06.09.2023

Linnaeus University is partnering with industry and healthcare to develop advanced biosensors, investing SEK 35 million in a project aimed at faster and cost-effective diagnoses of aggressive lung cancer, viral, and bacterial diseases, potentially enabling self-testing at home.
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Image: dr Jasmina Gačanin poses for the camera in a hallway; Copyright: Max-Planck-Institut für Polymerforschung

Max-Planck-Institut für Polymerforschung

Jasmina Gačanin investigates living biomaterials

20.07.2023

Dr. Jasmina Gačanin, postdoctoral researcher at the Max Planck Institute for Polymer Research in the department of Prof. Dr. Tanja Weil, has been appointed as a “Peretti-Schmucker Fellow”.
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Image: Magnetic nanoparticles (red) bind specifically to the spherical bacteria (yellow) which are about 1 µm in size (electron microscopy digitally colored); Copyright: Empa

Empa

Antibiotics crisis: rapid test for sepsis with nanoparticles

09.06.2023

For Qun Ren, every minute counts. The Empa researcher and her team are currently developing a diagnostic procedure that can detect life-threatening blood poisoning caused by staphylococcus bacteria rapidly. This is because staphylococcal sepsis is fatal in up to 40 percent of the cases.
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Image: Woman with glasses and gray-brown hair, Carole Planchette, stands by a pillar; Copyright: Fotogenia - Renate Trummer

Fotogenia - Renate Trummer

Tissue Engineering: TU Graz revolutionises production of biocompatible microfibres

02.06.2023

Using a newly developed method for the efficient and cost-effective production of biocompatible microfibres, the production of autologous skin and organs can be significantly accelerated. Responsible for the development are Carole Planchette and her team from TU Graz.
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Image: Prof. Dr. Thomas Scheibel and Vanessa Trossmann in a laboratory for the microscopic examination of cell structures; Copyright: UBT / Chr. Wißler.

UBT / Chr. Wißler.

Regenerative medicine: cell-specific properties of novel spider silk materials

12.05.2023

Materials made of spider silk can be specifically modified or processed in such a way that living cells of a certain type adhere to them, grow and proliferate. This has been discovered by researchers at the University of Bayreuth under the direction of Prof. Dr. Thomas Scheibel.
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Image: A transparent miniaturized muscle implant lies on a black table; Copyright: Fraunhofer IBMT

Fraunhofer IBMT

Human-machine interface stops muscle tremors

10.05.2023

Scientists at the Fraunhofer Institute for Biomedical Engineering IBMT have been working with international partners to develop a technology platform to help relieve the symptoms of muscle tremors.
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Image: A person in a white t-shirt is holding an anatomical model of the kidney in front of their abdomen; Copyright: PantherMedia/benschonewille

PantherMedia/benschonewille

Technology against organ shortage – Support for the successful transplant

03.02.2022

The waiting time for a donor organ is long nowadays since the need for organs vastly exceeds their availability. But we have possibilities to improve the situation and help as many people as possible to survive despite organ failure: Some organ functions can already be substituted by technology. But medicine is also researching ways to make more organs available for transplant.
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Image: A normothermic perfusion machine; Copyright: Charité – Universitätsmedizin Berlin

Charité – Universitätsmedizin Berlin

Machine Perfusion: Increasing the Safety of Marginal Organ Transplants

03.01.2022

The shortage of donor organs is a major global issue. An aging population, a reluctance towards organ donation, and logistical challenges related to organ shipping play an important role in this setting. Machine perfusion can be a way to expand and preserve the donor pool for eligible transplant recipients.
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Image: Image showing part of an ECMO machine – a square part through which blood is channeled; Copyright: PantherMedia/Richmanphoto

PantherMedia/Richmanphoto

COPD: How long before the implantable lung is here?

03.01.2022

Extracorporeal membrane oxygenation (ECMO) is often a last resort treatment for patients with acute respiratory failure. The method uses an external pump to circulate blood through an artificial lung back into the bloodstream. However, the use of ECMO for long-term support is not possible for patients with chronic respiratory failure.
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Image: Face and eye of a young woman in a close-up shot; Copyright: PantherMedia/Meseritsch Herby

PantherMedia/Meseritsch Herby

Implants for the senses – Hearing and seeing with technology

01.12.2021

We can replace certain functions of the body with implants nowadays, others we cannot. When it comes to the human senses, we are still quite at the beginning. The technologies and materials we can use are way to coarse compared to our nervous system. But implants can also help us to maintain senses.
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Image: Drawing inspiration from nature, a team of international scientists have invented a smart device for personalized skin care modeled after the male diving beetle; Copyright: McGill University

McGill University

A skin crawling treatment for acne

01.09.2021

Drawing inspiration from nature, a team of international scientists have invented a smart device for personalized skin care modeled after the male diving beetle. This tool collects and monitors body fluids while sticking to the skin’s surface, paving the way for more accurate diagnostics and treatment for skin diseases and conditions like acne.
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Image: Closeup view with selective focus of shiny glittering  water balls hydrogel; Copyright: PantherMedia/PhotoChowk

PantherMedia/PhotoChowk

Improving strength, stretchiness and adhesion in hydrogels for wound healing

31.08.2021

Scientists use the adhesive capabilities of mussels as a model for optimizing hydrogels’ mechanical properties.
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Image: A physician puts a bandage around the foot of a patient; Copyright: PantherMedia/Wavebreakmedia (YAYMicro)

PantherMedia/Wavebreakmedia (YAYMicro)

Chronic wounds: new, inexpensive wound dressing

29.07.2021

An MSU-led team is developing an inexpensive biopolymer dressing to heal injuries like diabetic foot ulcers that affect millions of patients all over the world.
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Image: A skull of a pig whose bones have been set using a white mass; Copyright: Daniel Hutchinson

Daniel Hutchinson

Fracture setting method could replace metal plates

02.07.2021

A new biocompatible polymer-based composite material could soon replace metal plates in treating difficult and unstable fractures. Developed at KTH Royal Institute of Technology in Stockholm, the newly-developed material is as strong as dental composites yet non-toxic.
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Image: Preview picture of video

Tissue Engineering and Bioprinting – From artificial heart valves and printed humans

27.01.2021

Drug research and artificial skin replacement - these are the areas in which tissue engineering and bioprinting are already used today. What else could be possible in the future? We asked Dr. Nadine Nottrodt from Fraunhofer ILT and Prof. Sabine Neuß-Stein from RWTH Aachen University Hospital!
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Image: cell matrix; Copyright: TU Wien

Multi-photon lithography: printing cells with micrometer accuracy

01.12.2020

How do cells react to certain drugs? And how exactly is new tissue created? This can be analyzed by using bioprinting to embed cells in fine frameworks. However, current methods are often imprecise or too slow to process cells before they are damaged. At the TU Vienna, a high-resolution bioprinting process has now been developed using a new bio-ink.
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Image: 3D printer with a human heart inside, next to a box with

Bioprinting: life from the printer

01.12.2020

It aims at the production of test systems for drug research and gives patients on the waiting lists for donor organs hope: bioprinting. Thereby biologically functional tissues are printed. But how does that actually work? What are the different bioprinting methods? And can entire organs be printed with it? These and other questions are examined in our Topic of the Month.
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Image: Illustrations of various 3D-printed prostheses, implants and organs; Copyright: PantherMedia/annyart

Printed life – possibilities and limits of bioprinting

01.12.2020

Implants, prostheses and various other components made of plastic, metal or ceramics are already being produced by additive manufacturing. But skin, blood vessels or entire organs from the printer – is that possible? For years now, intensive research has been underway into the production of biologically functional tissue using printing processes. Some things are already possible with bioprinting.
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Image: three vials, one with hydrogels, one with bio ink and one with unmodified gelatine; Copyright: Fraunhofer IGB

"Cells are highly sensitive" – material development for bioprinting

01.12.2020

The big hope of bioprinting is to someday be able to print whole human organs. So far, the process has been limited to testing platforms such as organs-on-a-chip. That's because the actual printing process already poses challenges. Scientists need suitable printing materials that ensure the cell's survival as it undergoes the procedure. The Fraunhofer IGB is researching and analyzing this aspect.
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Image: Surgical utensils lying on a table in the OR; Copyright: WavebreakmediaMicro - stock.adobe.com

Sustainable Nonwoven Solutions Improve Hygiene

02.11.2020

Whether it is hospitals or care homes - the right hygiene tools are crucial for process efficiency. These products can be composed of a wide variety of materials. NORAFIN offers a sustainable solution with products made from nonwoven fabric.
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Image: Physician checks function of an arm prosthesis; Copyright: PantherMedia/belahoche

PantherMedia/belahoche

Bionic prosthesis: easy to put on, intuitive to use

22.09.2020

Patients who receive a prosthesis after the amputation of a limb often have to train for weeks or months until they can control the technology and use it in everyday life without problems. At the Medical University of Vienna, the world's first bionic prosthesis has now been developed that has a closed control loop and enables immediate, intuitive use.
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Image: Two knees of a woman next to each other, the left knee has a surgical suture; Copyright: panthermedia.net/wujekspeed

Regenerative medicine: creating a new body?

03.02.2020

Regenerative medicine aims to repair the human body after injuries, accidents or major cancer surgery. Unfortunately, we are still not at a stage where this process can achieve optimal results for every conceivable situation. Having said that, various new methods are on the cusp of breakthrough.
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Image: A half-transparent red piece of tissue in a glass filled with a yellow fluid; Copyright: United Therapeutics

rhCollagen: genetically engineered building block for regenerative medicine

03.02.2020

Collagen is the stuff that holds our bodies together and that houses our cells. In regenerative medicine, it is also the stuff that can be applied to wounds to support healing. However, collagen from animal or human sources has some drawbacks for today’s medicine. This is where rhCollagen from the Israeli company CollPlant comes into play.
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Image: patient with pain in fingers; Copyright: panthermedia.net/Milkos

APRICOT-project: implant "help(s) patients heal themselves"

01.01.2020

Today, people tend to live longer, while an increasing number of patients suffer from osteoarthritis. Even younger generations are now at a higher risk of getting osteoarthritis due to the frequent use of mobile devices. The EU research project APRICOT aims to develop a novel type of implant for the treatment of osteoarthritis of the hands – helping patients heal themselves.
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Image: Athlete with knee pain; Copyright: panthermedia.net/Wavebreakmedia Itd

Endoprostheses: between possibility and reality

01.01.2020

When natural joints lose their ability to function, they can be completely or partially replaced by artificial joints, also called endoprostheses. Endoprostheses must be of a certain quality, as they should remain in the body as long as possible. In addition to some risks, endoprostheses can also contribute to a mobile and carefree life for young and old.
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