microgen
TissueGrinder: Improved cell analyses via enhanced-quality sample preparation
07.12.2023
A new method for examining tissue samples could change the way we diagnose and treat cancer. Researchers at the Max Planck and Fraunhofer IPA have developed an automated system based on the principle of enzyme-free tissue processing and the mechanical deformability of individual cells.
JoPanwatD
Pancreas: nanoparticles for optimized cancer therapy
23.11.2023
Researchers from Göttingen and Karlsruhe have developed a new treatment approach for pancreatic cancer. The innovative method promises to be able to treat the disease in a more targeted way and with fewer side effects in the future. The therapy is now to be optimized for clinical application as quickly as possible.
Brandon Martin/Rice University
Affordable global health technologies for early cancer detection
06.11.2023
A Rice University-led collaboration from three continents has won up to a five-year grant from the National Institutes of Health to establish a premier research center in the Texas Medical Center to develop affordable, effective point-of-care (POC) technologies that improve early cancer detection in low-resource settings in the United States and other countries.
Medical University of Vienna
Skin cancer diagnoses using AI are as reliable as those made by medical experts
02.11.2023
An Austrian-Australian research team led by dermatologist Harald Kittler from MedUni Vienna investigated the extent to which diagnosis and therapy of pigmented skin lesions benefit from it in a realistic clinical scenario.
umg/Dr. Dolma Choezom
Project CANACO: better imaging-based and targeted therapy of colon cancer
01.11.2023
The University Medical Center Göttingen (UMG) is coordinating the development of a new nanoparticle-based method for the personalized therapy of patients suffering from colon cancer.
Oxford Nanopore
Nanopore sequencing and DNA barcoding method gives hope of personalised medicine
03.10.2023
With the ability to map dozens of biomarkers at once, a new method could transform testing for conditions including heart disease and cancer.
ORION_production
AI model to improve accuracy of breast cancer tumor removal
02.10.2023
A new clinical and research partnership has created an AI model that can predict whether or not cancerous tissue has been fully removed from the body during breast cancer surgery.
Christian Wißler/UBT
EXIST funding for bacterial magnetic nanoparticles
28.09.2023
BioMagnetix uses bacterial magnetic nanoparticles as innovative materials for biomedical applications. The founding team aims to develop and continuously improve high-quality and highly functional magnetic nanoparticles for imaging techniques and therapeutic purposes, such as cancer treatment.
MPIMIS
Cellular cartography: sizes and abundance revealed
27.09.2023
An international team of scientists has created the first comprehensive index of human cells, mapping the sizes and abundance of all cell types across the entire body.
wosunan
Microrobots: opportunities for cancer treatment and wound healing
18.09.2023
A group of researchers at the Technical University of Munich (TUM) has developed the world’s first microrobot (“microbot”) capable of navigating within groups of cells and stimulating individual cells.
Karolinska Institutet
Breast cancer: more cases detected with the help of AI
15.09.2023
One radiologist supported by AI detected more cases of breast cancer in screening mammography than two radiologists working together, reports the ScreenTrustCAD study from Karolinska Institutet in The Lancet Digital Health.
Jonna Alanko/Science Immunology
How immune cells migrate
11.09.2023
When fighting disease, our immune cells need to reach their target quickly. Researchers at the Institute of Science and Technology Austria (ISTA) now discovered that immune cells actively generate their own guidance system to navigate through complex environments.
Joakim Palmqvist
Advanced biosensors to detect tumors, viruses and bacterial diseases
06.09.2023
Linnaeus University is partnering with industry and healthcare to develop advanced biosensors, investing SEK 35 million in a project aimed at faster and cost-effective diagnoses of aggressive lung cancer, viral, and bacterial diseases, potentially enabling self-testing at home.
Beate Armbruster/University Hospital of Tuebingen
Protection for cancer patients
05.09.2023
Tübingen T-cell activator offers protection against coronaviruses in immunocompromised patients
Karin Kaiser / MHH
More impact against cancer
04.09.2023
MHH molecular physician Professor Dr. Dr. Schambach wants to use genetically modified natural killer cells to find new therapeutic options against three particularly malignant cancers. The EU is funding the project with 3.8 million euros
Kateryna Maksymenko
Innovative computational approach helps design proteins for cancer treatment
31.08.2023
A joint team of researchers from the Max Planck Institute for Biology Tübingen and the University Hospital Tübingen has now developed and tested a new computational method to greatly speed up the necessary energy calculations.
LMU
Immunotherapy: Antibody kit to fight tumors
25.08.2023
A new study highlights the potential of artificial DNA structures that, when fitted with antibodies, instruct the immune system to specifically target cancerous cells.
Gerain0812
Sensor-controlled precision: the future of surgical tumor removal
22.08.2023
The complete removal of malignant tumors is a decisive factor for the success of cancer treatment. Until now, the tissue examinations required for this have been time-consuming. In the future, sensor-based methods could come into play to help surgeons detect tumor boundaries more accurately and thus perform a more precise operation.
Wavebreakmedia
Study: Fluidity predicts aggressiveness of cancerous tumours
17.08.2023
Researchers discovered that the consistency of a tumor can have a decisive influence on the further course of cancer.
ORION_production
AI-supported mammography screening is found to be safe
11.08.2023
Mammography screening supported by artificial intelligence (AI) is a safe alternative to today’s conventional double reading by radiologists and can reduce heavy workloads for doctors.
Eijiro Miyako from JAIST
Cancer photoimmunotherapy: novel liquid metal nanoparticles
10.08.2023
JAIST researchers create liquid metal nanoparticles (PEG-IMIQ-LM) for cancer treatment, merging photothermal therapy and immunotherapy. Disintegration delivers immunomodulants and tracks cancer cells in real-time. Immune checkpoint inhibitor enhances cancer removal. Promising for future cancer theranostics, with clinical trials anticipated in a decade.
Inside Creative House/Shutterstock
Skin cancer diagnosis: reinforcement learning for improved performance of AI
02.08.2023
An international research team led by Harald Kittler of MedUni Vienna has now explored a learning method in which greater accuracy in AI results can be achieved by incorporating human decision-making criteria.
Paul Scherrer Institut
Improvement of the CT: earlier detection of breast cancer
26.07.2023
A team of researchers from the Paul Scherrer Institute PSI and ETH Zurich, together with the Baden Cantonal Hospital (KSB) and the University Hospital Zurich (USZ), has succeeded in refining mammography, x-ray imaging technique used to detect tumours in their early stages, to produce considerably more reliable results and be less unpleasant for the patient.
Zinkevych_D
Breast cancer: international expert recommendations on removal of lymph nodes
24.07.2023
Researchers from Heidelberg University Hospital and the University of Lucerne as well as international scientists, patient representatives and European cancer societies have pooled scientific data and their expert knowledge on the surgical management of lymph nodes in breast cancer.
KIMM
3D bioprinting technology to be used for removing cancer cells
14.07.2023
KIMM develops the world’s first 3D bioprinting technology that enhances the function of NK immune cells. The new technology is expected to improve effectiveness of cancer treatment.
EKFZ
AI against bowel cancer: research project DECADE
12.07.2023
The DECADE research project is the first to use swarm learning in cancer research. The German Cancer Aid is funding the joint project of several university hospitals with around 1.5 million euros.
Prostock-studio
Molecular tumor profiling: blood test to determine the optimal cancer therapy
11.07.2023
If a tumor is diagnosed, tissue samples are usually investigated to determine the molecular tumor profile for personalized cancer treatment. However, tissue biopsy cannot be performed in all affected individuals. Therefore, the University Hospital Zurich has licensed a liquid biopsy for the analysis of more than 300 genes and offers this test as a modern diagnostic method to tumor patients.
rawf8
Improved cancer therapy: TimeTeller shows what makes the body tick
06.07.2023
Using the internal clock to optimize chemotherapies in cancer treatment - that is the goal of the start-up TimeTeller. If the drugs are administered at the ideal time of day for chemotherapy, it can reduce side effects and improve the effect. TimeTeller has developed a method for determining the internal clock to make this possible.
University of Gothenburg
Skin cancer: curettage and cryosurgery effective for basal cell carcinoma
30.06.2023
The number of cases of skin cancer is continuing to rise sharply, in Sweden and internationally, involving high costs for a healthcare economy that is already under severe strain in many places. Eva Backman and her team studied the efficacy of treatment options.
University Hospital of Bonn (UKB)
Metastatic renal cell carcinoma: improved prediction of therapy response
29.06.2023
The study demonstrates a significant improvement in predicting the response to therapy in metastatic renal cell carcinoma by incorporating the level of inflammation, which was assessed using two straightforward blood parameters, alongside the conventional imaging-based approach.
Universidad de Barcelona
New biomarkers of non-small cell lung cancer discovered
27.06.2023
Researchers of the University of Barcelona and the Institute of Bioengineering of Catalonia (IBEC) have identified new biomarkers for non-small cell lung cancer, the most common lung cancer.
Maxwell Miner
PET imaging: discovery can help detect brain tumours
22.06.2023
Folate-based radiopharmaceuticals can be used in positron emission tomography (PET) imaging to detect folate receptors in brain tumours. The discovery of folate receptors and their exploitation potential with respect to brain tumours is a new and significant finding in the field.
Gregor Hübl / Universität Bonn
Researching organoids: two new Argelander Professors at the University of Bonn
21.06.2023
Two new assistant professors at the University of Bonn are setting out to develop “mini-organs” in order to study metabolic and disease mechanisms.
Dennis Gankin / TUM
Algorithm helps search for the cause of hereditary diseases
07.06.2023
A Munich research team has developed an algorithm that predicts the effects of genetic mutations on RNA formation six times more precisely than previous models.
B. Schröder/HZDR
Cancer: new theranostic for imaging and treatment
01.06.2023
Thanks to the radiation they emit, radioactive compounds are suited both to imaging and treating cancers. By appropriately combining them in novel, so-called radionuclide theranostics, both applications can be dovetailed.
Karin Kaiser / MHH
With ultrasound against liver cancer
24.05.2023
The Hannover Medical School (MHH) enters into a clinic partnership with Uzbekistan and supports with a training program for sonography diagnostics of hepatocellular carcinoma (HCC).
Anna Schroll/Leibniz-HKI
Model shows intestinal bacteria influence growth of fungi
22.05.2023
The bacteria present in the intestine provide information about the quantities of fungi of the potentially disease-causing Candida genus.
University of Surrey
UK AI world leader in identifying location and expression of proteins
18.05.2023
A new advanced artificial intelligence (AI) system has shown world-leading accuracy and speed in identifying protein patterns within individual cells.
Berend Snijder Lab / ETH Zurich
How to fight blood cancer more effectively
05.05.2023
Despite approved treatments being available, multiple myeloma remains incurable. But researchers at ETH Zurich and University Hospital Zurich set out to improve treatment outcomes by testing hundreds of existing therapeutics outside the body to predict their effectiveness.
UCD Research and Innovation
Novel combination of therapies may provide new treatment option for bone cancer
03.05.2023
New research has identified a potential therapeutic target and developed a unique delivery system to treat osteosarcoma, a bone cancer that primarily affects children and adolescents.
INP
Plasma against precancerous skin lesions: EU funds international doctoral candidates network
24.04.2023
Under the leadership of the Leibniz Institute for Plasma Science and Technology (INP), the international doctoral candidates network PlasmACT is investigating the use of medical gas plasma technology as a treatment method.
Cyborg and Bionic Systems
Novel robotic bronchoscope system for navigation and biopsy of pulmonary lesions
19.04.2023
A novel robotic bronchoscope system can non-intrusively access the area of interest within the lung for minimally invasive pulmonary lesions sampling, the gold standard of lung cancer diagnoses.
RUB, Marquard
Ultrasound activates anticancer agent
14.04.2023
Chemotherapy treatments produce strong side effects. A new agent that accumulates in the tumour tissue and is activated there by ultrasound waves does not have this problem.
Peter Winandy
Novel technology for hollow organ tumour therapy
10.04.2023
Ioana Slabu from the Institute of Applied Medical Technology and Benedict Bauer from the Institut für Textiltechnik of RWTH Aachen University have developed a novel technology for the therapy of hollow organ tumours, which was awarded second place in the RWTH Innovation Award.
Universidad de Barcelona
Microfluidics physics-based device to predict cancer therapy response
06.04.2023
A team of experts has designed a microfluidic device called microfluidic dynamic BH3 profiling (μDBP) that predicts the effectiveness of cancer treatment quickly and automatically.
ONWARD Medical NV
PANDORA test could pave the way for better oral cancer detection
06.04.2023
Surrey scientists have developed a proof-of-concept test called PANDORA that was shown to be over 92% accurate at identifying patients with oral squamous cell carcinoma (OSCC). The test was also shown to be more than 80% accurate at identifying patients with pre-cancer or oral epithelial dysplasia (OED).
Gustavo Raskosky/Rice University
Upgraded tumor model optimizes search for cancer therapies
27.03.2023
Rice University researchers developed an upgraded tumor model that houses osteosarcoma cells beside immune cells known as macrophages inside a three-dimensional structure engineered to mimic bone. Using the model, bioengineer Antonios Mikos and collaborators found that the body’s immune response can make tumor cells more resistant to chemotherapy.
Karin Kaiser/MHH.
Better care for pregnant women with precancerous cervical cancer
23.03.2023
Preliminary stages of cervical cancer occur mainly in women between 25 and 35 years of age. The main risk factor for developing cervical cancer is the human papillomavirus (HPV). Surgery is the treatment of choice.
University of the West of Scotland
Radiology: Research could improve cancer treatment
22.03.2023
UWS School of Computing Engineering and Physical Sciences are developing breakthrough investigations into advanced radiation treatment technique, after receiving funding from Cancer Research UK RadNet – the charity's radiation research network.
JoPanwatD
AI finds targets for CAR-T cell therapy against acute myeloid leukemia
20.03.2023
Unlike other forms of blood cancer, acute myeloid leukemia (AML) cannot currently be treated with CAR-T cell immunotherapy. The reason is that specific molecular targets with which certain immune cells could specifically target AML cells are lacking, which would permit the immune system to attack cancer.
Natabuena
Ultrasound method could lead to easier disease diagnosis in body tissue
17.03.2023
A new ultrasound method that can measure the level of tension in human tissue for the first time - a key indicator of disease - has been developed by researchers from the University of Sheffield.
manjurulhaque
RIANA: Viennese start-up develops novel, precise anti-cancer drugs
14.03.2023
The technological basis is a proprietary platform technology for the discovery of drugs that target cancer-causing protein-protein interactions (PPIs).
AG Hoelzel/UKB
Artificial intelligence to help tumor immunology
09.03.2023
Developing methods to predict the nature of the tumor microenvironment is the goal of researchers from the Clusters of Excellence ImmunoSensation2 and the Hausdorff Center for Mathematics (HCM) led by Prof. Kevin Thurley at the University of Bonn.
FBH/P. Immerz
Entangled photon pairs to help fighting cancer
06.03.2023
The recently launched QEED project aims to significantly reduce measurement time in clinical cancer diagnostics by developing a spectrally resolved imaging technique based on entangled photon pairs. FBH scientists will develop the required diode lasers and quantum light modules.
RUB, Marquard
AI with infrared imaging enables precise colon cancer diagnostics
23.02.2023
Researchers at the Centre for Protein Diagnostics PRODI at Ruhr University Bochum, Germany, are using artificial intelligence in combination with infrared imaging to optimally tailor colon cancer therapy to individual patients.
Karin Kaiser / MHH, Freepik.com
MHH leads EU large-scale project for personalized cancer care
26.01.2023
CAN.HEAL aims to expand the available innovations in cancer prevention, diagnosis and treatment in the Member States in order to improve care for all patients in the EU. The project focuses on measures of personalized medicine. Genomics is an important cornerstone for this.
The University of Hong Kong
'Reduce and Remove': new treatment strategy for locally advanced liver cancer
19.01.2023
A pioneering phase II clinical study on tri-modality therapy (START-FIT), conducted by the Department of Surgery and Department of Clinical Oncology, School of Clinical Medicine, LKS Faculty of Medicine of the University of Hong Kong (HKUMed), has found that nearly 50% of patients with inoperable locally advanced liver cancer, can be cured through such an innovative approach.
Medical University of Vienna
Locally advanced cervical cancer: Better odds using personalized brachytherapy
17.01.2023
For the first time, a study conducted by a research group at the Comprehensive Cancer Centre Vienna of MedUni Vienna and Vienna General Hospital using data from the multicentre EMBRACE-I trial demonstrated the superiority of a targeted approach in brachytherapy.
Amac Garbe/Fraunhofer IWS
Radioactive substances fight cancer in the mini-lab
13.01.2023
Two Dresden research institutes want to reduce the number of animal experiments in radiopharmaceutical research with a new idea.
Universitätsklinikum Bonn (UKB)
AI improves colorectal cancer screening in Lynch syndrome
10.01.2023
Researchers at the National Center for Hereditary Tumor Diseases (NZET) at Bonn University Hospital (UKB) have now found that artificial intelligence (AI) can improve the effectiveness of colonoscopy in the presence of Lynch syndrome.
Aalto University
Gaining unprecedented view of small molecules by machine learning
06.01.2023
A new tool to identify small molecules offers benefits for diagnostics, drug discovery and fundamental research. A new machine learning model will help scientists identify small molecules, with applications in medicine, drug discovery and environmental chemistry.
sofiiashunkina
Complete package for minimally invasive tumor therapy
04.01.2023
License agreement and joint development: Fraunhofer MEVIS commences cooperation with Israeli partner for worldwide use of innovative software technology in ultrasound-aided tumor ablation.
DC_Studio
Diagnosing breast cancer through liquid biopsy
22.09.2022
Breast cancer diagnosis usually includes invasive testing with tissue biopsies. The samples have to be extracted from the cancerous tissue or cells. To make the process easier on the patients, the project LIBIMEDOTS is currently developing a different approach with liquid biopsy technology.
Susanne Vondenbusch-Teetz, MPI for Biochemistry
Deep Visual Proteomics: tracking down cancer
08.09.2022
Proteins are frequently called the building blocks of life because they are found everywhere, including in our cells. This makes them an important factor when it comes to diseases. As a result, mapping the protein landscape can be a crucial ally in the fight against diseases. Now, a German-Danish team has developed a method that provides researchers with unprecedented insights into cancer.
ktsimage
Big Data in genetics: reaching diagnosis through heaps of data
01.08.2022
Most laboratory tests only produce small amounts of data that are already sufficient for successful diagnosis. It becomes more difficult with genetic questions: whether it is about a genetic disease or the properties of tumors, there are large amounts of data that must be considered. Both research and medicine need help to identify the connections and patterns in the data to find a diagnosis.
LipiTUM
MoSBi: Algorithm identifies disease subtypes
01.08.2022
Doctors have always used symptoms, imaging, and laboratory data to define and diagnose diseases, but at times it is simply not enough: while patients may have the same illness, it may exhibit different changes at the molecular level. A team from the Technical University of Munich has developed the so-called MoSBi algorithm and makes it available to researchers to identify molecular differences.
Felix Petermann | MDC
Project "ikarus" provides new insights for cancer research
01.08.2022
Artificial intelligence (AI) is about to become a game changer, especially in diagnostics. However, there are still limits to the use of AI. Dr. Altuna Akalin had to recognize this as well. The head of the Max Delbrück Center's (MDC) technology platform for "Bioinformatics and Omics Data Science" developed "ikarus" with his team.
Karin Kaiser/MHH
Prevention of cervical cancer with HPV self-testing
28.10.2021
Cervical cancer is one of the most common diseases of the female reproductive organs. Human papilloma viruses are almost always responsible for cervical cancer and the corresponding precancerous lesions. As part of the statutory preventive medical check-up, women from the age of 20 can have a cell smear taken from the cervix once a year, the so-called Pap test, to detect cell changes.
Christian Morawe/Universitätsmedizin Magdeburg
Histotripsy: fighting tumors with microbubbles
08.09.2021
Focused ultrasound waves create microbubbles in a fluid – a phenomenon called cavitation. In a current study, this process is used to destroy liver tumors and metastases.
St Vincent's Hospital Melbourne
New AI tech for early detection of prostate cancer
16.07.2021
Prostate cancer is the most diagnosed cancer and a leading cause of death by cancer in Australian men. Early detection is key to successful treatment, but men often dodge the doctor, avoiding diagnosis tests until it is too late.
Tumor therapy: drug delivery pump instead of injection
01.02.2021
Drugs always have undesired side effects. Cytostatics are powerful drugs used to treat cancer. They reach almost all cells in the body, killing healthy cells as well as cancer cells in the process. A targeted delivery to the specific cellular site would be a gentler treatment.
Autonomous medical devices: running well in your body
01.02.2021
In theory, autonomous medical technologies can be used in a diagnostic or therapeutic capacity inside the body under certain conditions. This may not sound like a new invention at first. After all, implantable cardioverter-defibrillators have monitored and fixed abnormal heart rhythm for many years.
Leibniz-IPHT/Sven Döring
Tumor excision: triple imaging for unique diagnostics
08.08.2019
After their tumor has been removed, some patients have to return to the hospital to undergo surgery again. That's because the tumor was not precisely identified and was subsequently not completely removed. That's both an ethical and financial dilemma. A new surgery-adjacent procedure is designed to rapidly and accurately detect tumors.
Functional Imaging: The puls of modern oncology
17.06.2019
Medical imaging techniques have developed considerably in recent decades. In addition to morphological imaging techniques more and more functional imaging techniques are used in oncology that can continously record the functions of specific organs locally and regionally in real time. These are groundbreaking for diagnostics, therapies and preoperative preparations.
Where imaging and radiation meet – Radiotherapy with the MR-Linac
13.02.2019
In conventional radiotherapy, the tumor is first localized using CT and MRT images in order to calculate the irradiated areas. The major drawback in this case: the subsequent radiation only shows bone structures in the body but not the tumor itself. As a result, the radiated area is often larger than necessary. In our video you will learn how the MR-Linac can be used for more precise radiotherapy.