Red light as the key to gene activity control
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Optimizing infection diagnostics with AI, masks and antibody tests

01.10.2024

Due to the increasing global challenges within infection diagnostics, it is becoming ever more important to develop new methods and technologies. Antibiotic resistance, changing disease patterns and new types of infections underline the importance of specific medical technology solutions.
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Image: An environmentally friendly rapid antigen test placed on a green leaf; Copyright: Okos Diagnostics

Okos Diagnostics

From waste to sustainable wins: Rapid tests with biomaterials

27.08.2024

Over 2 billion rapid test (lateral flow assay) kits are produced every year, adding tens of thousands of tons of used materials to the growing global volume of medical waste. Every test kit contains around 12 grams of plastic and is designed for single use. The company Okos Diagnostics, founded in 2022, aims to reduce the waste with a sustainable rapid test solution.
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Image: Two researchers standing in a laboratory, wearing red light goggles and holding an agar plate in their hands; Copyright: UBT/Andreas Möglich

UBT/Andreas Möglich

Red light as the key to gene activity control

30.07.2024

In a new study, the University of Bayreuth has investigated the sensitivity of bacterial systems for controlling gene activity to red light. These research results open up a wide range of possibilities for the biotechnological application of bacteria. The results of the study have been published in Nature Communications.
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Image: Researchers examine DNA samples and discuss biomedical treatment

Blood tests: Tracking down cancer with circulating DNA

30.07.2024

Liquid biopsies in the form of blood tests offer the possibility of analyzing circulating free DNA in the blood and thus improving cancer therapies. The advantage of diagnostics using blood tests is that they can help to detect tumors at an early stage and efficiently monitor the progression of cancer.
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Image: Close-up of an FFP2 mask; Copyright: Research Center Borstel, Leibniz Lung Center

Research Center Borstel, Leibniz Lung Center

Tuberculosis diagnosis in children with modified FFP2 mask

09.07.2024

The diagnosis of tuberculosis (TB) in children poses a particular challenge. While adults can often be diagnosed by detecting genetic material in their sputum, this is often not possible in children as they rarely produce sputum.
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Inage: Sitting pregnant woman holding her belly with both hands; Copyright: djoronimo

djoronimo

Pre-eclampsia diagnosis in focus: MOMM Diagnostics' rapid test

22.12.2023

Early diagnosis is crucial in the case of pregnancy toxemia or pre-eclampsia. The young company MOMM Diagnostics is developing a diagnostic tool to help detect pre-eclampsia quickly and accurately. The start-up was already able to present an initial prototype of préXclude at MEDICA 2023. Clinical trials are due to start soon.
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Image: Close up: Positive COVID rapid test in a tray; Copyright: elenabednykh

elenabednykh

AI used in new COVID-19 test improves accuracy

06.12.2023

A new AI-assisted molecular diagnostic platform capable of identifying variants of COVID-19 and other infectious diseases has been developed by scientists in the UK. The low cost, portable device could play a crucial role in preventing future pandemics due to its accuracy and versatility.
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Image: Abstract virus blood cells; Copyright: Malmö University

Malmö University

New sensors could replace current infection testing

04.10.2023

New technology could pave the way to a future of rapid testing in hospitals and at home for both covid and urinary tract infection. It could also be used to keep track of blood sugar levels during operations and wireless monitoring of various bacterial infections.
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Image: Close-up of a Covid test tube; Copyright: stetphotos

stetphotos

Rapid electronic diagnostic test for infectious diseases

04.10.2023

A new molecular test for bacteria and viruses, including SARS-CoV-2 has been developed by scientists at the University of Surrey, as they warn that the world needs to be prepared for the next pandemic.
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COMPASS: Inexpensive and fast detection method for viruses

02.10.2023

Since Corona, everyone has probably come into contact with a rapid test for checking viral load. A new device called COMPASS promises much faster and more effective testing than conventional methods. It was developed by researchers at Julius Maximilian University in Würzburg in cooperation with Erlangen University Hospital.
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Image: Half-bald man with glasses in a dark jacket stands in the sunshine and smiles into the camera; Copyright: Ryan Hull

Ryan Hull

Pathogen detection through electronic detection of DNA nanoballs

19.09.2023

Researchers at Karolinska Institute have developed a novel method using DNA Nanoballs to detect pathogens, aiming to simplify nucleic acid testing and revolutionize pathogen detection.
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Image: A woman hands a yellow piece of paper to a man across a table where another person is also sitting; Copyright: InfectoGnostics

InfectoGnostics

InfectoGnostics study: Benefits of on-site tests in general practices

05.09.2023

General practitioners (GP) regularly use on-site rapid tests because they find their application useful. However, frequent utilisation fails due to costs and remuneration regulations. These are the results of a study by InfectoGnostics researchers at the University Hospital Jena in the project "POCT-ambulant", in which 292 GPs in Thuringia, Bremen and Bavaria participated.
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Image: A woman in personal protective clothing examines samples under a microscope; Copyright: monkeybusiness

monkeybusiness

Pandemic prevention: progress in research infrastructure

15.08.2023

The Covid-19 pandemic has clearly shown that there is still a lot of potential in research structures and funding to better manage a pandemic. Prevention plays just as important a role as dealing with the pandemic. Technological measures that can facilitate virus detection or help to analyze the course in more detail need to be developed.
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Image: Petri dish with bacterial cultures in laboratory; Copyright: felipecaparros

felipecaparros

Noninvasive technology tests for malaria without a blood sample

07.08.2023

A novel testing platform under development by researchers at the Yale School of Public Health (YSPH) and CytoAstra, LLC could provide a new noninvasive test for malaria that doesn’t require a blood sample.
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Image: Magnetic nanoparticles (red) bind specifically to the spherical bacteria (yellow) which are about 1 µm in size (electron microscopy digitally colored); Copyright: Empa

Empa

Antibiotics crisis: rapid test for sepsis with nanoparticles

09.06.2023

For Qun Ren, every minute counts. The Empa researcher and her team are currently developing a diagnostic procedure that can detect life-threatening blood poisoning caused by staphylococcus bacteria rapidly. This is because staphylococcal sepsis is fatal in up to 40 percent of the cases.
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Image: One man and two women posing for the camera with a building in the background; Copyright: Karolinska Institutet

Karolinska Institutet

New method reveals bacterial reaction to antibiotics in five minutes

26.05.2023

Researchers at Karolinska Institutet in Sweden have developed a molecular method able to detect whether or not bacteria respond to antibiotics within minutes.
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Image: A doctor takes a saliva sample from a patient in an examination room; Copyright: Prostock-studio

Prostock-studio

TimeTeller: tenth spin-off of the BIH Digital Health Accelerator

25.05.2023

An interdisciplinary team led by Prof. Angelo Relógio, a scientist at Charité’s Molecular Cancer Research Center (MKFZ) and Institute for Theoretical Biology and the MSH Medical School Hamburg, has developed a non-invasive method for profiling a person’s unique circadian rhythm.
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Image: Close up of test tubes in a laboratory; Copyright: leungchopan

leungchopan

AI helps create better, simpler hepatitis, COVID-19 tests

11.05.2023

University of Florida scientists have used artificial intelligence tools to simplify a test that works for both hepatitis C and SARS-CoV-2, the virus that causes COVID-19. The simplified test happens in one small test tube in just a few minutes.
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Image: ENT doctor or dentist with a medical instrument examining the oral cavity; Copyright: YuriArcursPeopleimages

ONWARD Medical NV

PANDORA test could pave the way for better oral cancer detection

06.04.2023

Surrey scientists have developed a proof-of-concept test called PANDORA that was shown to be over 92% accurate at identifying patients with oral squamous cell carcinoma (OSCC). The test was also shown to be more than 80% accurate at identifying patients with pre-cancer or oral epithelial dysplasia (OED).
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Image: Picture of the complete sensor with a PDMS well of 100 μl volume for the drop test; Copyright: HZDR/Sandoval Bojorquez

HZDR/Sandoval Bojorquez

Nanobiosensor developed for detecting SARS-CoV-2

04.04.2023

Infection and immunity status of the population are considered key parameters for handling pandemics. For this purpose, detecting antigens and antibodies is of great importance. The devices currently used for this purpose - what are known as point-of-care (POC) devices- are one option for rapid screening. Their sensitivity, however, needs further improvement.
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Image: Illustration of the nanomaterial graphene with gold nano disks array; Copyright: NTNU

NTNU

Super quick COVID test uses new technology

13.02.2023

The ability of gold particles to reflect light in different colours is used in applications from stained glass to pregnancy tests. Now researchers are set to exploit the same properties in an ultra-fast sensor for the coronavirus.
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