06.12.2023A new AI-assisted molecular diagnostic platform capable of identifying variants of COVID-19 and other infectious diseases has been developed by scientists in the UK. The low cost, portable device could play a crucial role in preventing future pandemics due to its accuracy and versatility.
04.12.2023A research team headed by Professor Julia Bandow and Dr. Tim Dirks from the Chair for Applied Microbiology at Ruhr University Bochum, Germany, showed that bacteria that overproduce the heat shock protein Hsp33 can withstand plasma treatment more effectively than others.
01.12.2023A coating process can be used to treat fabrics in such a way that bacterial and viral pathogens are killed or inhibited in their growth. In hospitals, the coated textiles could be used in future as antimicrobial curtains between patient beds, for example.
24.11.2023Factors associated with hospital admissions, ICU stays and mortality in patients who have had SARS-CoV-2 are identified, and clinical prediction rules are developed.
21.11.2023In the context of the tenure negotiations for Drug Bioinformatics Professor Olga Kalinina, the Klaus Faber Foundation is providing €100,000 to the "bioINFpro" project, thereby enabling her long-term stay at the Helmholtz Institute for Pharmaceutical Research Saarland (HIPS) and Saarland University.
07.11.2023There is a low-cost way for you to protect yourself and reduce your risk of respiratory diseases such as flu, RSV, and COVID-19. Build yourself a Corsi-Rosenthal box (CR box) in 30 minutes with just $60 worth of common hardware store supplies.
31.10.2023An international research team from the University of Cologne and the Icahn School of Medicine, Mount Sinai (New York) has developed a model that predicts the likely evolution of variants of the SARS-CoV-2 virus.
25.10.2023A researcher team from Ecole Polytechnique Federal de Lausanne led by Dr. Vivek Thacker now group leader at the Department of Infectious Diseases at Heidelberg University Hospital have studied why tuberculosis bacteria form long strands and how this affects their infectivity.
04.10.2023A new molecular test for bacteria and viruses, including SARS-CoV-2 has been developed by scientists at the University of Surrey, as they warn that the world needs to be prepared for the next pandemic.
04.10.2023New technology could pave the way to a future of rapid testing in hospitals and at home for both covid and urinary tract infection. It could also be used to keep track of blood sugar levels during operations and wireless monitoring of various bacterial infections.
22.09.2023Scientists from the Chair of Materials Science and Nanotechnology at TU Dresden (TUD) have made considerable progress in the development of highly innovative solutions for the detection of viral pathogens in two studies they presented recently.
19.09.2023Researchers at Karolinska Institute have developed a novel method using DNA Nanoballs to detect pathogens, aiming to simplify nucleic acid testing and revolutionize pathogen detection.
06.09.2023Linnaeus University is partnering with industry and healthcare to develop advanced biosensors, investing SEK 35 million in a project aimed at faster and cost-effective diagnoses of aggressive lung cancer, viral, and bacterial diseases, potentially enabling self-testing at home.
24.08.2023MHH researcher Prof. Galardini from the RESIST Cluster of Excellence finds causes for bloodstream infections in the genes of bacteria. This will enable better diagnostics and vaccinations in the future.
14.08.2023Aspergillus fumigatus strains that infect humans have a significantly altered metabolism compared to other strains in the environment. At the same time, infection with the fungus leads to an apparent change in the human lung microbiome.
10.08.2023Researchers at TU Graz have gained new insights into the functioning of a protein found in bacteria, whose enzymatic activity is activated by blue light.
07.08.2023A novel testing platform under development by researchers at the Yale School of Public Health (YSPH) and CytoAstra, LLC could provide a new noninvasive test for malaria that doesn’t require a blood sample.
27.07.2023Scripps Research scientists have developed a machine-learning system—a type of artificial intelligence (AI) application—that can track the detailed evolution of epidemic viruses and predict the emergence of viral variants with important new properties.
13.07.2023Scientists are looking at ways to surveil indoor environments in real time for viruses. By combining recent advances in aerosol sampling technology and an ultrasensitive biosensing technique, researchers at Washington University in St. Louis have created a real-time monitor that can detect any of the SARS-CoV-2 virus variants in a room in about 5 minutes.
07.07.2023Researchers develop and test highly efficient, environmentally friendly and stable antimicrobial (antibacterial, antiviral, antifungal) coating technologies in the NOVA project.
23.06.2023The UPC’s Biomaterials, Biomechanics and Tissue Engineering Group (BBT) leads the international project Bio-TUNE, which aims to develop multifunctional materials with high antibacterial potential and efficient tissue integration.
21.06.2023Researchers at the Helmholtz Institute for Pharmaceutical Research Saarland (HIPS) have developed a novel method to place biofilms on lung cells in the laboratory. The model system produced by means of "bioprinting" should help to better understand infection processes and assist in the development of new active substances.
15.06.2023Why is the SARS-CoV-2 coronavirus able to spread so efficiently? Various hypotheses are still circulating in the scientific community. A group of researchers from Würzburg has now found groundbreaking answers.
13.06.2023We know from previous studies that changes in the lung microbiome are associated with diseases such as cystic fibrosis, asthma or chronic obstructive pulmonary disease (COPD). Environmental factors such as smoking, nutrition in infancy or the use of antibiotics are important factors for the composition and stability of the microbial community in the lung.
12.06.2023The Institute for Drug Discovery led by Humboldt Professor Jens Meiler is to receive 1.9 million dollars (1.77 million euros) for the development of vaccines. The international Coalition for Epidemic Preparedness Innovations (CEPI) will fund computer-aided vaccine development at Leipzig University with the aim of building a digital ‘vaccine library’ of components and virtual antigen designs.
09.06.2023For Qun Ren, every minute counts. The Empa researcher and her team are currently developing a diagnostic procedure that can detect life-threatening blood poisoning caused by staphylococcus bacteria rapidly. This is because staphylococcal sepsis is fatal in up to 40 percent of the cases.
26.05.2023Researchers at Karolinska Institutet in Sweden have developed a molecular method able to detect whether or not bacteria respond to antibiotics within minutes.
24.05.2023The Hannover Medical School (MHH) enters into a clinic partnership with Uzbekistan and supports with a training program for sonography diagnostics of hepatocellular carcinoma (HCC).
23.05.2023A study conducted by the Department of Molecular and Medical Virology at Ruhr University Bochum, Germany, has shown that temperature is a major factor in this process: at room temperature, a monkeypox virus that is capable of replicating can survive on a stainless steel surface for up to eleven days, and at four degrees Celsius for up to a month.
22.05.2023The bacteria present in the intestine provide information about the quantities of fungi of the potentially disease-causing Candida genus.
11.05.2023University of Florida scientists have used artificial intelligence tools to simplify a test that works for both hepatitis C and SARS-CoV-2, the virus that causes COVID-19. The simplified test happens in one small test tube in just a few minutes.
04.05.2023Heidelberg researchers describe mechanisms that could help prevent infections with the influenza A and Ebola viruses.
02.05.2023“We have developed a technique in our laboratories that allows us to obtain an antibiogram within 2-4 hours – instead of the current 24 hours for the most common germs and one month for tuberculosis,” says Dr Sandor Kasas at EPFL.
07.04.2023A paper produced as part of the DAKI-FWS project (data and AI-supported early warning system to stabilize the German economy) will be featured in the prestigious journal Nature Medicine.
05.04.2023From now on, an improved research infrastructure for pandemic management and prevention will be available in the Greater Munich area: on the 29th of March 2023 a new biosafety level 3 laboratory was introduced at Helmholtz Munich.
04.04.2023Infection and immunity status of the population are considered key parameters for handling pandemics. For this purpose, detecting antigens and antibodies is of great importance. The devices currently used for this purpose - what are known as point-of-care (POC) devices- are one option for rapid screening. Their sensitivity, however, needs further improvement.
31.03.2023Andreas Dräger from the University of Tübingen is working on a computer-based method that can help to accelerate the time-consuming identification and development of antiviral agents.
23.03.2023Preliminary stages of cervical cancer occur mainly in women between 25 and 35 years of age. The main risk factor for developing cervical cancer is the human papillomavirus (HPV). Surgery is the treatment of choice.
16.03.2023Researchers at Lund University in Sweden have now developed a software solution for smart, data-driven microscopy, which makes this possible.
07.03.2023Project led by PMI member Prof. Andre Franke aims to empower people affected by Crohn’s disease and ulcerative colitis by developing interdisciplinary solutions for improved disease prevention and health promotion.
27.02.2023Georgia Institute of Technology researchers have found a way to use small shocks of electricity to disinfect water, reducing energy consumption, cost, and environmental impact.
13.02.2023The ability of gold particles to reflect light in different colours is used in applications from stained glass to pregnancy tests. Now researchers are set to exploit the same properties in an ultra-fast sensor for the coronavirus.
08.02.2023A new junior research group at Freie Universität Berlin, which will investigate the production of biodegradable antiviral and antibacterial materials, with one of the goals of synthesis being new alternatives to conventional antibiotics, will receive a total budget of more than 1.8 million euros from the German Federal Ministry of Education and Research (BMBF) over the next five years.
07.02.2023A group of researchers at Chalmers University of Technology in Sweden are presenting a new spray that can kill even antibiotic-resistant bacteria, and that can be used for wound care and directly on implants and other medical devices.
03.02.2023George Mason University researchers found that computerized symptom screenings can supplement at-home COVID-19 tests to better confirm the diagnosis for patients and clinicians.
27.01.2023The electrical potential across the bacterial cell envelope indicates when bacteria no longer operate as individual cells but as a collective. Researchers at the University of Cologne's Institute for Biological Physics have discovered this connection between the electrical properties and the lifestyle of bacteria.
26.01.2023The underlying mechanisms of long COVID are not yet fully understood. Molecular clues to different subgroups of long COVID have now been provided by a research group at University Medicine Halle.
23.01.2023Rapid switching between different antibiotics could prevent the evolution of resistance and lead to successful treatment of patients.
18.01.2023Researchers at the Helmholtz Institute for RNA-based Infection Research (HIRI) and the Julius-Maximilians-Universität (JMU) in Würzburg have developed a technology they call TIGER. It allows complex processes in individual cells to be deciphered in vivo by recording past RNA transcripts.
12.01.2023Researchers at Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU) and Julius-Maximilians-Universität Würzburg have developed a method for binding specific molecules in samples and serums, such as antibodies in the blood, to the surface of iron oxide particles thus allowing them to be identified using an inexpensive and compact detector.
11.01.2023The first study of its kind that used smartwatches to monitor the physiological data of close to 5,000 Israelis for two years found that: Monitoring heart measures using smartwatches shows that the Corona booster vaccine is safe and there is no evidence of unusual adverse events.
09.01.2023A newly developed rapid test needs only a few seconds to reliably detect pathogens such as SARS-CoV-2. It is based on specially designed magnetic nanoparticles.
05.01.2023With a multimodal microscope, the Laser Zentrum Hannover e.V. (LZH) and three partners in the joint project PriMe want to make it possible to detect bacterial infestation using fast, marker-free, and contactless imaging.
20.12.2022Using a new analytical method, Empa researchers have tracked viruses as they pass through face masks and compared their failure on the filter layers of different types of masks.
15.12.2022Researchers from the Bioengineering and Biomaterials Laboratory of Universidad Católica de Valencia (UCV) have developed a new porous material capable of regenerating bones and preventing infections at the same time.
12.12.2022Producing infection control clothing requires a lot of energy and uses lots of material resources. Fraunhofer researchers have now developed a technology which helps to save materials and energy when producing nonwovens.
22.08.2022A team of scientists from the Berlin Institute of Health at Charité (BIH) together with colleagues from the United Kingdom and Canada have found genes and proteins that contribute to a higher risk of severe COVID-19.
02.05.2022Disinfection and sterilization are the most reliable and best way to ensure patient safety in healthcare settings. Whether it is at the point of care when the patient is either at the hospital or medical practice, or wherever medical devices are manufactured and packaged in a sterile environment – the transmission of pathogens and microorganisms can have severe health impacts.
02.05.2022Due to the Corona pandemic, a lot of attention is currently focused on the protective effect of medical masks. But especially in medical work areas, the protection against aerosol transmission is not enough, because a lot of pathogens can be transmitted trough direct contact with people or surfaces. Hygienic measures against contact infections like these are very costly, though.
02.05.2022One of the most time-consuming tasks in hospitals is the manual cleaning and disinfection of high touch points and surfaces such as door handles, buttons, and switches. These are areas where microorganisms are spread by direct skin contact. The “MobDi – Mobile Disinfection” research project is developing a robot that automatically cleans and disinfects these areas. It will use cold plasma.
25.01.2022Researchers at the University of Washington have developed a new test for COVID-19 that combines the speed of over-the-counter antigen tests with the accuracy of PCR tests that are processed in medical labs and hospitals.
22.12.2021Despite myriad precautionary measures, virus-contaminated aerosols still pose a serious problem indoors. An invisible protective wall of UV-C ligh could provide a solution and reliably curb the spread of viruses and other pathogens in rooms in the future while allowing total freedom of movement.
01.10.2021In the laboratory, there is some work that is time-consuming and monotonous – making it the perfect place for digital solutions such as artificial intelligence or robotics. But what work can these systems really take on in a meaningful way, in which areas of the lab are they present today, and where do they still need to be improved?
01.10.2021They have probably never been in the spotlight as much as during the pandemic: laboratories. In Germany alone, around 73 million COVID-19-tests have been evaluated since the beginning of 2020. And even away from Corona, laboratory physicians have a lot to do – blood, urine and aspirates have to be evaluated every day. That results in an enormous amount of work, just in terms of organization.
22.06.2021Architecture can prevent infections in hospitals. The walk-in model of a new type of patient room shows how this can be done. It was developed by a team from the fields of architecture, medicine and molecular biology in the KARMIN research project.
25.05.2021One of the most time-consuming tasks in a hospital is the disinfection of often-used surfaces like light switches or door handles. This is especially important during the corona pandemic. The "DeKonBot" by Fraunhofer IPA could support hospital staff here in the future. Learn in our video interview with Dr. Birgit Graf how the robot works.
16.03.2021Using supercomputer numerical modeling of saliva droplets' diffusion produced by coughs, researchers in Italy explore deactivating COVID-19 virus particles via UV-C light.
01.03.2021All hospitalized patients are susceptible to contracting a nosocomial infection, with ICU patients being particularly at risk. The effects of these hospital-acquired infections are often more dangerous than the original reason for the in-patient hospitalization. The "PACMAN" project is now testing an antimicrobial coating for frequently used contact surfaces at high risk of pathogen transmission.
03.02.2021Medical hygiene does not just play a key role during the COVID-19 pandemic. Preventing the transmission of infectious diseases and especially the spread of multidrug-resistant organisms is paramount even in non-pandemic times. While hygiene practices in hospitals and medical offices are essential, the industry can also make an important contribution with hygienic product design.
19.01.2021The risk of infection with SARS-CoV-2 is particularly high indoors. This is because, in addition to smear and droplet infection, infection via aerosols that accumulate and spread in the air is also possible there. Sufficient air exchange or air purification help to prevent this. The protective canopy developed by Fraunhofer IBP also follows such an approach.
02.11.2020Healthcare settings require sharp weapons to fight both hospital-acquired infections and pathogens like SARS-CoV-2. Besides protective equipment, regular room disinfection is one of them. But they require time and are also prone to error if done manually. Fully automated solutions are needed to relief hospital staff from this exhausting work and perform it reliably. So, why not fog the room?
01.04.2020When working with infectious materials and organisms in the laboratory, safe handling and appropriate training are of utmost importance. Another central component is personal protective equipment designed to prevent contact with tissue, liquids and aerosols and protect the wearer.
01.04.2020Laboratories are sectioned into four biosafety levels to dictate the precautions required to isolate dangerous biological agents. The highest level of biological safety, BSL-4, is perhaps the most well-known when we think of containing pathogens and microbes. However, the fewest number of laboratories actually fall into the BSL-4 category.
01.04.2020What goes in, must not come out - and must also not cause harm to anyone working inside the lab. That's perhaps a nice way of summing up "laboratory safety" in one sentence - at least wherever pathogens are handled in biological and medical settings. The necessary laboratory safety precautions primarily depend on what is waiting "inside".
01.04.2020When biomedical researchers or diagnosticians work with potentially contagious materials like cell cultures, blood or tissue, they need absolute protection from pathogens. Both safety measures in the workspace and the correct tools and materials are key here. Learn in our Topic of the Month what is important for protection in the lab and what a safe laboratory looks like.
31.03.2020Besides hand hygiene, drinking water hygiene is also on the to-do list of every hospital. A lot of money is invested to clean water pipes and to destroy legionella germs. An alternative solution for mechanical and thermal control is water disinfection using an automatic machine.
23.03.2020Germs such as bacteria, viruses or pathogenic fungi can spread from one person to another through direct contact when we shake hands or touch objects. People touch door handles and push elevator buttons in public places and constantly move in and out of spaces. Regular manual high-level disinfection is practically impossible. UVentions GmbH has found an intelligent solution for this problem.
01.01.2020When natural joints lose their ability to function, they can be completely or partially replaced by artificial joints, also called endoprostheses. Endoprostheses must be of a certain quality, as they should remain in the body as long as possible. In addition to some risks, endoprostheses can also contribute to a mobile and carefree life for young and old.
01.01.2020Surgery is required if you need an artificial joint. Patients and doctors must select the type of surgery that’s best suited and choose between robot-assisted, traditional or minimally invasive surgical approaches. Post-operative risks should be kept to a minimum, while benefits should outweigh any possible complications.
01.01.2020Today, people tend to live longer, while an increasing number of patients suffer from osteoarthritis. Even younger generations are now at a higher risk of getting osteoarthritis due to the frequent use of mobile devices. The EU research project APRICOT aims to develop a novel type of implant for the treatment of osteoarthritis of the hands – helping patients heal themselves.
01.01.2020Joints can suddenly or gradually deteriorate and lose their natural strength, whether it’s due to accidents, diseases or simple wear and tear. In some of these cases, implants of artificial joints – endoprostheses - can help. As a joint replacement, they are designed to stay in the body for as long as needed and as such improve the patient’s quality of life and mobility.
04.11.2019Soon, the world's largest trade fair for medical technology will open its doors again: More than 5.000 exhibitors will present their newest products and ideas at MEDICA from 18 to 21 November. You will not only meet well-known companies here, but also lots of young start-ups. Or, you can visit the MEDICA forums and conferences to experience a rich program of lectures and discussions.
01.08.2019Antibiotic resistance is on the rise in all parts of the world, complicating medical treatment of serious bacterial infections in patients. The World Health Organization estimates that approximately 33,000 people die each year from antibiotic-resistant bacteria in Europe alone. Bacteria that are resistant to multiple or even all known antibiotics pose an ever-increasing threat.
01.08.2019An untreatable infection is a nightmare for physicians and potentially life-threatening to the patient. Unfortunately, more and more pathogens emerge that are resistant to drugs, especially antibiotics. We need to use our drugs smartly and come up with technical solutions as well to prevent our weapons from blunting in the future.
01.08.2019Antibiotic resistance is modern medicine's greatest challenge. Some bacteria only respond to a handful of antibiotics, prompting hospitals to spend a lot of time finding an effective drug. That’s why it is critical for physicians to rapidly identify antibiotic resistance to avoid ineffective treatments.
01.08.2019The medical devices value chain has gaps between academic research and industrial practice that slow down innovation processes. This also applies to time-sensitive and urgently needed products such as rapid diagnostic tests to identify resistant pathogens. At the InfectoGnostics Research Campus in Jena, partners from research and medicine team up to close these gaps.