21/09/2023Technology, developed by researchers from the Knoblich group at the Institute of Molecular Biotechnology (IMBA) of the Austrian Academy of Sciences and the Treutlein group at ETH Zurich, permits the identification of vulnerable cell types and gene regulatory networks that underlie autism spectrum disorders.
20/09/2023Is it possible that a single biomarker can detect all types of diseases related to dopamine deficiency in the brain? Yes, that's what a research group in Lund is discovering.
19/09/2023Researchers at Karolinska Institute have developed a novel method using DNA Nanoballs to detect pathogens, aiming to simplify nucleic acid testing and revolutionize pathogen detection.
05/09/2023Tübingen T-cell activator offers protection against coronaviruses in immunocompromised patients
29/08/2023Cooperation between the University of Bonn, the USA and the Netherlands cracks the mode of action of clovibactin
25/08/2023Cooking food thoroughly and avoiding some types of vegetables and salad during a course of antibiotic treatment could potentially reduce antibiotic resistance, by preventing bacteria carrying resistance genes getting into the gut, according to a new study.
25/08/2023A new study highlights the potential of artificial DNA structures that, when fitted with antibodies, instruct the immune system to specifically target cancerous cells.
24/08/2023MHH researcher Prof. Galardini from the RESIST Cluster of Excellence finds causes for bloodstream infections in the genes of bacteria. This will enable better diagnostics and vaccinations in the future.
22/08/2023The team of Dr. Elisha Krieg at the Leibniz Institute of Polymer Research Dresden has developed a dynamic DNA-crosslinked matrix (DyNAtrix) by combining classical synthetic polymers with programmable DNA crosslinkers.
31/07/2023Researchers at Karolinska Institutet in Sweden, among others, have now found that artificial intelligence seems to play a role in identifying the risk of cardiovascular disease.
20/07/2023Artificial intelligence is becoming increasingly important in drug discovery. Advances in the use of Big Data, learning algorithms and powerful computers have now enabled researchers at the University of Zurich (UZH) to better understand a serious metabolic disease.
04/07/2023In the midst of the COVID-19 pandemic, scientists and researchers have been tirelessly working to develop innovative and accurate tests to identify the presence of viruses. One breakthrough technology that has emerged is the combination of artificial intelligence (AI) and CRISPR, which has revolutionized virus detection.
28/06/2023The Ataxia Center at the University Hospital Bonn (UKB) and DZNE have been awarded the title “Ataxia Center of Excellence” by the US National Ataxia Foundation (NAF) for their patient care and research – as the only organization in Europe.
16/06/2023Being to identify people at high risk of chronic disease means that they can be targeted with prevention measures before they become sick. Polygenic risk scores, where genomic information alone is used to assess the risk of developing diseases, have been receiving a lot of attention recently.
16/06/2023Huntington’s disease is a genetically-based neurodegenerative disorder that causes motor, cognitive and psychiatric disorders in the affected individuals. Understanding the alterations in the neural circuits in this disorder is essential in order to design therapeutic approaches.
14/06/2023Researchers from the UK and Germany have used artificial intelligence (AI) to develop a system that they believe will enable more widespread provision of testing, together with improved efficiency.
13/06/2023We know from previous studies that changes in the lung microbiome are associated with diseases such as cystic fibrosis, asthma or chronic obstructive pulmonary disease (COPD). Environmental factors such as smoking, nutrition in infancy or the use of antibiotics are important factors for the composition and stability of the microbial community in the lung.
07/06/2023A Munich research team has developed an algorithm that predicts the effects of genetic mutations on RNA formation six times more precisely than previous models.
18/05/2023A new advanced artificial intelligence (AI) system has shown world-leading accuracy and speed in identifying protein patterns within individual cells.
17/05/2023Most of the AI-generated algorithms have databases with populations of European origins and they ignore the genetic and morphological diversity of human populations of around the world.
11/05/2023An international research team, comprising scientists from University Hospital Bonn, DZNE, the Netherlands, and the US has been awarded a US$ 1.3 million grant by the “Human Frontier Science Program” to investigate brain immune cells and manipulate them via light irradiation.
09/05/2023A team led by bioinformatics experts Andreas Keller and Fabian Kern from Saarland University together with researchers at Stanford University have gained new insights into manifestations of ageing at the molecular level.
03/05/2023Researchers at Karolinska Institutet in Sweden have mapped how cells in the human spinal cord are formed in the embryo and what genes control the process.
03/05/2023New research has identified a potential therapeutic target and developed a unique delivery system to treat osteosarcoma, a bone cancer that primarily affects children and adolescents.
27/04/2023Max Planck and Harvard research teams develop DeMAG, a new method shared as an open-source web server (demag.org) to help interpret mutations in disease genes and improve clinical decision-making.
13/04/2023In cooperation with Helmholtz Munich, Professor Matthias Meier from the Centre for Biotechnology and Biomedicine at Leipzig University and his research group have developed a new, effective and comparatively inexpensive method to make rare cell types, cell communication types and disease patterns visible in tissue.
30/03/2023Light therapy has demonstrated its usefulness in treating a variety of diseases. But can it delay the occurrence of age-related disease? The answer may be yes, according to a study in mice published in February in Lasers in Surgery and Medicine.
24/03/2023Together with partners from science and industry, Fraunhofer IPK is researching how mRNA therapeutics and other medication can be better produced and more effectively applied.
08/03/2023Using artificial intelligence (AI) methods, researchers led by Professor Dr Alexander Schönhuth from Bielefeld University’s Faculty of Technology have succeeded in recording and deciphering the genotype profiles of 3,000 ALS patients and thus learning more about the development of the disease.
02/03/2023In the ImageTox project, the Helmholtz Institute for Pharmaceutical Research Saarland (HIPS) and the CISPA Helmholtz Center for Information Security are pooling their expertise in the fields of drug discovery and artificial intelligence (AI).
01/03/2023Infection with SARS-CoV-2 leads to severe disease in some people, while others do not get ill or only experience mild disease. But why is this the case? Unfortunately, we do not know exactly. We do know that an overactive innate immune system is causing severe COVID-19 disease, but it is unclear how this is regulated.
17/02/2023DNA can help to stimulate bone healing in a localised and targeted manner, for example after a complicated fracture or after severe tissue loss following surgery.
16/02/2023A team led by Prof Claus-Michael Lehr of the Helmholtz Institute for Pharmaceutical Research Saarland (HIPS) has developed a novel human lung cell line that should enable much more accurate predictions of the behavior of active substances or dosage forms in humans than previous systems.
16/02/2023Research led by scientists at St George’s, University of London has discovered 119 areas in the genome that help to determine the size and shape of blood vessels at the back of the eye, and that an increase in ‘twisting’ of the arteries could cause high blood pressure and heart disease.
13/02/2023The ability of gold particles to reflect light in different colours is used in applications from stained glass to pregnancy tests. Now researchers are set to exploit the same properties in an ultra-fast sensor for the coronavirus.
27/01/2023Hunting for disease clues in the dark matter of our DNA. Scientists have reconstructed the chromosomes of patients with an extremely high number of aberrations in their genome that could alter the expression of nearby genes and potentially cause disease. Their results were published in Nature Communications in October 2022.
26/01/2023CAN.HEAL aims to expand the available innovations in cancer prevention, diagnosis and treatment in the Member States in order to improve care for all patients in the EU. The project focuses on measures of personalized medicine. Genomics is an important cornerstone for this.
18/01/2023Researchers at the Helmholtz Institute for RNA-based Infection Research (HIRI) and the Julius-Maximilians-Universität (JMU) in Würzburg have developed a technology they call TIGER. It allows complex processes in individual cells to be deciphered in vivo by recording past RNA transcripts.
10/01/2023Researchers at the National Center for Hereditary Tumor Diseases (NZET) at Bonn University Hospital (UKB) have now found that artificial intelligence (AI) can improve the effectiveness of colonoscopy in the presence of Lynch syndrome.
22/08/2022A team of scientists from the Berlin Institute of Health at Charité (BIH) together with colleagues from the United Kingdom and Canada have found genes and proteins that contribute to a higher risk of severe COVID-19.
01/08/2022Artificial intelligence (AI) is about to become a game changer, especially in diagnostics. However, there are still limits to the use of AI. Dr. Altuna Akalin had to recognize this as well. The head of the Max Delbrück Center's (MDC) technology platform for "Bioinformatics and Omics Data Science" developed "ikarus" with his team.
01/08/2022Most laboratory tests only produce small amounts of data that are already sufficient for successful diagnosis. It becomes more difficult with genetic questions: whether it is about a genetic disease or the properties of tumors, there are large amounts of data that must be considered. Both research and medicine need help to identify the connections and patterns in the data to find a diagnosis.
01/08/2022Doctors have always used symptoms, imaging, and laboratory data to define and diagnose diseases, but at times it is simply not enough: while patients may have the same illness, it may exhibit different changes at the molecular level. A team from the Technical University of Munich has developed the so-called MoSBi algorithm and makes it available to researchers to identify molecular differences.
01/08/2022Big data, the use of large volumes of data in diagnostics and research, is giving medical science a powerful boost. Especially in laboratory medicine, big data can provide unprecedented support as doctors must consider a multitude of data and parameters to facilitate accurate medical decision-making.
02/09/2021Philippine Genome Center Mindanao (PGC Mindanao) has partnered with Accessible Genomics, a group of volunteering scientists from all around the world to implement a low start-up cost genomic sequencing platform for laboratories in developing countries.
31/08/2021Determining an individual’s blood group based on genetic tests instead of merely traditional blood tests can provide a better picture of the risk of cardiovascular diseases.
29/07/2021Scientists have developed a rapid, highly accurate test to detect antibodies against the spike protein of SARS-CoV-2 in human serum, opening a new avenue for understanding the full extent of the pandemic and evaluating the effectiveness of vaccines.
15/06/2021Many modern fitness trackers and smartwatches feature integrated LEDs. The green light emitted, whether continuous or pulsed, penetrates the skin and can be used to measure the wearer's heart rate during physical activity or while at rest.
03/02/2020Collagen is the stuff that holds our bodies together and that houses our cells. In regenerative medicine, it is also the stuff that can be applied to wounds to support healing. However, collagen from animal or human sources has some drawbacks for today’s medicine. This is where rhCollagen from the Israeli company CollPlant comes into play.
01/08/2019Antibiotic resistance is modern medicine's greatest challenge. Some bacteria only respond to a handful of antibiotics, prompting hospitals to spend a lot of time finding an effective drug. That’s why it is critical for physicians to rapidly identify antibiotic resistance to avoid ineffective treatments.
15/05/2019New active substances that are suitable for drugs are initially tested in animal experiments. However, the results cannot always be transferred to the human organism. At the Karlsruhe Institute of Technology, Prof. Ute Schepers from vasQlab explains how active substances can be tested in human tissue without endangering human health.