23.10.2023How are synapses formed, those points of contact that allow the transmission of information from one neuron to the other? Working with an international team, researchers from the Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP) have now uncovered a crucial mechanism and elucidated the identity of the axonal transport vesicles that generates synapses.
09.05.2023Researchers have designed a new stem cell model to study congenital diaphragmatic hernia in newborns with underdeveloped lungs. They were able to isolate stem cells from the fluid that is suctioned from the baby’s lungs and normally gets discarded and use them as a foundation for the model.
24.04.2023In a new study published in Proceedings of the National Academy of Sciences, University of Pittsburgh researchers developed a novel approach that promoted bone regeneration in mice without implantation of bone tissue or biomaterials.
20.04.2023Novel microelectrode array system enables long-term cultivation and electrophysiological analyses of brain organoids.
12.04.2023In a joint project of the Max Planck Institute for Polymer Research, Mainz, and the Translational Center for Regenerative Therapies at the Fraunhofer Institute for Silicate Research ISC, Würzburg, scientific principles and biomaterials for the standardized production of valid tissue models are to be developed.
11.04.2023The team working with Alessandra Moretti, Professor of Regenerative Medicine in Cardiovascular Disease, has developed a method for making a sort of "mini-heart" using pluripotent stem cells.
20.03.2023Unlike other forms of blood cancer, acute myeloid leukemia (AML) cannot currently be treated with CAR-T cell immunotherapy. The reason is that specific molecular targets with which certain immune cells could specifically target AML cells are lacking, which would permit the immune system to attack cancer.
15.03.2023Congenital diaphragmatic hernia is one of the deadliest birth defects. To better understand and treat this condition in the future, an international team of researchers involving Leipzig University Hospital designed a new cell model in the laboratory and tested a drug therapy on it.
10.03.2023Researchers at the Translational Center for Regenerative Therapies TLC-RT of the Fraunhofer Institute for Silicate Research ISC want to work with partners to replace animal testing.
03.03.2023Synthetic hydrogels were shown to provide an effective scaffold for neuronal tissue growth in areas of brain damage, providing a possible approach for brain tissue reconstruction.
03.03.2023A research group at Uppsala University has developed a simple and effective artificial blood-brain barrier model that can be used to determine how well antibody-based therapies can enter the brain.
25.01.2023Fraunhofer researchers have now developed a new method for the production and clinical application of stem-cell-based retinal implants, which could contribute towards the successful treatment of AMD.
27.01.2021Drug research and artificial skin replacement - these are the areas in which tissue engineering and bioprinting are already used today. What else could be possible in the future? We asked Dr. Nadine Nottrodt from Fraunhofer ILT and Prof. Sabine Neuß-Stein from RWTH Aachen University Hospital!
15.09.2020Some tasks in the laboratory are repetitive, need to be done extremely precise and require a lot of time. Such tasks are very tedious for humans, but they are tailor-made for robots. Such is the case with the "AutoCRAT" project at the Fraunhofer Institute for Production Technology IPT in Aachen. Here, a robotic platform is developed to produce stem cells for the treatment of osteoarthritis.
03.02.2020Severe wounds heal slowly and leave scars. This is why we have been using regenerative therapies for some time now to accelerate and improve healing. They also help to avoid permanent damage. Still, complex applications like replacing organs or limbs will rather remain vision than become reality for a long time.
03.02.2020Regenerative medicine aims to repair the human body after injuries, accidents or major cancer surgery. Unfortunately, we are still not at a stage where this process can achieve optimal results for every conceivable situation. Having said that, various new methods are on the cusp of breakthrough.
01.02.2019Organ-on-a-chip systems are technically a great enhancement of medical research because they facilitate testing of active ingredients on cell cultures in the chambers of a plastic chip. This replaces animal testing and improves patient safety. That being said, they are not a true-to-life replication of the human body and can only simulate a few functions and activities.