08.12.2023Titanium hip implants do not last forever — they gradually loosen, sooner or later losing their hold on the bone as it recedes over time. Researchers at the Fraunhofer IAP have been working alongside the Fraunhofer IGB and the Fraunhofer CMI to develop a tissue adhesive that can help avoid early replacement of prostheses in the future.
30.11.2023Over the next five years, the ERC will provide two million euro of funding for the development of a new class of electronic components that consist almost entirely of water and could make the interface between biological tissue and machine seamless.
28.11.2023Open-source supercomputer algorithm predicts patterning and dynamics of living materials and enables studying their behavior in space and time.
21.11.2023In the context of the tenure negotiations for Drug Bioinformatics Professor Olga Kalinina, the Klaus Faber Foundation is providing €100,000 to the "bioINFpro" project, thereby enabling her long-term stay at the Helmholtz Institute for Pharmaceutical Research Saarland (HIPS) and Saarland University.
09.11.2023A broken bone failing to heal represents an enormous burden for patients. Fraunhofer researchers have worked alongside partners to develop a composite material to be used in the treatment of such non-union cases. The resulting implant is designed to significantly improve treatment success rates and speed up the healing process.
09.10.2023Addressing the impact of female menopause on dynamic resilience and exploring preventive and therapeutic strategies is the aim of an international and interdisciplinary research group led by Prof. Dr. Peter Loskill from the NMI Natural and Medical Sciences Institute and the Eberhard Karls University of Tübingen.
04.10.2023New technology could pave the way to a future of rapid testing in hospitals and at home for both covid and urinary tract infection. It could also be used to keep track of blood sugar levels during operations and wireless monitoring of various bacterial infections.
28.09.2023BioMagnetix uses bacterial magnetic nanoparticles as innovative materials for biomedical applications. The founding team aims to develop and continuously improve high-quality and highly functional magnetic nanoparticles for imaging techniques and therapeutic purposes, such as cancer treatment.
22.09.2023Scientists from the Chair of Materials Science and Nanotechnology at TU Dresden (TUD) have made considerable progress in the development of highly innovative solutions for the detection of viral pathogens in two studies they presented recently.
21.09.2023Technology, developed by researchers from the Knoblich group at the Institute of Molecular Biotechnology (IMBA) of the Austrian Academy of Sciences and the Treutlein group at ETH Zurich, permits the identification of vulnerable cell types and gene regulatory networks that underlie autism spectrum disorders.
18.09.2023A group of researchers at the Technical University of Munich (TUM) has developed the world’s first microrobot (“microbot”) capable of navigating within groups of cells and stimulating individual cells.
06.09.2023Linnaeus University is partnering with industry and healthcare to develop advanced biosensors, investing SEK 35 million in a project aimed at faster and cost-effective diagnoses of aggressive lung cancer, viral, and bacterial diseases, potentially enabling self-testing at home.
23.08.2023A new method allows large quantities of muscle stem cells to be safely obtained in cell culture.
09.08.2023PeptiMatrix is the latest spin-out company from the University of Nottingham, providing access to an innovative 3D cell culture platform that aims to replace the use of animals in research.
28.07.2023The team of Prof. Dr. Thomas Scheibel, Chair of Biomaterials at the University of Bayreuth, has compiled a current overview of the state of research on protein-based bioadhesives.
28.07.2023Developing technology to quickly and efficiently bioprint human tissues at scale is the goal of a new project led by Penn State researchers. When fully developed, the technology will be the first to enable the fabrication of scalable, native tissues such as bones, tracheas and organs.
26.07.2023Like us, cells communicate. Well, in their own special way. Using waves as their common language, cells tell one another where and when to move.
20.07.2023Dr. Jasmina Gačanin, postdoctoral researcher at the Max Planck Institute for Polymer Research in the department of Prof. Dr. Tanja Weil, has been appointed as a “Peretti-Schmucker Fellow”.
18.07.2023The findings in mice provide unprecedented insights into the complexity of large-scale neural networks and brain plasticity. Moreover, they could pave the way for new brain-inspired artificial intelligence methods.
14.07.2023KIMM develops the world’s first 3D bioprinting technology that enhances the function of NK immune cells. The new technology is expected to improve effectiveness of cancer treatment.
13.07.2023Scientists are looking at ways to surveil indoor environments in real time for viruses. By combining recent advances in aerosol sampling technology and an ultrasensitive biosensing technique, researchers at Washington University in St. Louis have created a real-time monitor that can detect any of the SARS-CoV-2 virus variants in a room in about 5 minutes.
06.07.2023Using the internal clock to optimize chemotherapies in cancer treatment - that is the goal of the start-up TimeTeller. If the drugs are administered at the ideal time of day for chemotherapy, it can reduce side effects and improve the effect. TimeTeller has developed a method for determining the internal clock to make this possible.
27.06.2023Knee osteoarthritis is a widespread form of arthrosis that limits those affected in their everyday lives. The wear and tear in the cartilage tissue often causes pain and movement restrictions. In order to improve treatment, researchers have developed a process that allows artificial cartilage tissue to be individually tailored to sufferers.
23.06.2023The UPC’s Biomaterials, Biomechanics and Tissue Engineering Group (BBT) leads the international project Bio-TUNE, which aims to develop multifunctional materials with high antibacterial potential and efficient tissue integration.
23.06.2023Researchers from Empa and ETH Zurich have developed a plaster with a sensor function to ensure that wounds in the abdomen remain tightly closed after an operation.
21.06.2023Researchers at the Helmholtz Institute for Pharmaceutical Research Saarland (HIPS) have developed a novel method to place biofilms on lung cells in the laboratory. The model system produced by means of "bioprinting" should help to better understand infection processes and assist in the development of new active substances.
21.06.2023Two new assistant professors at the University of Bonn are setting out to develop “mini-organs” in order to study metabolic and disease mechanisms.
13.06.2023Treating large-area and internal wounds and promoting their often protracted healing remains a challenging task for medicine. Researchers at the Fraunhofer Institute for Silicate Research (ISC) and the Fraunhofer Institute for Toxicology and Experimental Medicine (ITEM) have developed the bioresorbable membrane RENACER®.
09.06.2023For Qun Ren, every minute counts. The Empa researcher and her team are currently developing a diagnostic procedure that can detect life-threatening blood poisoning caused by staphylococcus bacteria rapidly. This is because staphylococcal sepsis is fatal in up to 40 percent of the cases.
02.06.2023Using a newly developed method for the efficient and cost-effective production of biocompatible microfibres, the production of autologous skin and organs can be significantly accelerated. Responsible for the development are Carole Planchette and her team from TU Graz.
24.05.2023Researchers in the UNC School of Medicine's Department of Microbiology and Immunology and the UNC-NC State Joint Department of Biomedical Engineering have developed a new strategy to improve drug-delivery into chronic wounds infections.
19.05.2023Wavy wounds heal faster than straight wounds because shapes influence cell movements, a team of researchers at Nanyang Technological University, Singapore (NTU Singapore) has found.
17.05.2023The Wake Forest Institute for Regenerative Medicine (WFIRM) will make history this month when the first bioprinted solid tissue constructs soar to the International Space Station (ISS) on board the next all private astronaut mission by commercial space leader Axiom Space.
12.05.2023Materials made of spider silk can be specifically modified or processed in such a way that living cells of a certain type adhere to them, grow and proliferate. This has been discovered by researchers at the University of Bayreuth under the direction of Prof. Dr. Thomas Scheibel.
11.05.2023An international research team, comprising scientists from University Hospital Bonn, DZNE, the Netherlands, and the US has been awarded a US$ 1.3 million grant by the “Human Frontier Science Program” to investigate brain immune cells and manipulate them via light irradiation.
09.05.2023A team led by bioinformatics experts Andreas Keller and Fabian Kern from Saarland University together with researchers at Stanford University have gained new insights into manifestations of ageing at the molecular level.
08.05.2023An interdisciplinary team of scientists in Dresden developed novel bio-inspired sugar-based molecules that show potential to improve bone regeneration.
27.04.2023Not all advances in medical technology immediately catch your eye – take biologicals, for example. These are molecules that are biotechnologically designed for a specific application. In the German state of Baden-Württemberg, the Biologicals Development Center (BioDevCenter) and its infrastructure aim to bring them to market faster in the future.
26.04.2023A nanocellulose wound dressing that can reveal early signs of infection without interfering with the healing process has been developed by researchers at Linköping University, Sweden.
21.04.2023Researchers have developed an artificial intelligence-based method for virtual staining of histopathological tissue samples as a part of the Nordic ABCAP consortium.
20.04.2023Novel microelectrode array system enables long-term cultivation and electrophysiological analyses of brain organoids.
19.04.2023In the process of organoid manufacturing, bioprinting technology not only facilitates the creation and maintenance of complex biological 3D shapes and structures, but also allows for standardization and quality control during production.
13.04.2023In cooperation with Helmholtz Munich, Professor Matthias Meier from the Centre for Biotechnology and Biomedicine at Leipzig University and his research group have developed a new, effective and comparatively inexpensive method to make rare cell types, cell communication types and disease patterns visible in tissue.
12.04.2023In a joint project of the Max Planck Institute for Polymer Research, Mainz, and the Translational Center for Regenerative Therapies at the Fraunhofer Institute for Silicate Research ISC, Würzburg, scientific principles and biomaterials for the standardized production of valid tissue models are to be developed.
11.04.2023The polymerase chain reaction, or PCR, plays a major role both in the diagnosis of infectious diseases and in research. Since the onset of the COVID-19 pandemic, the term has become widely known. At MEDICA 2022, the BLINK AG from Jena, Germany, presented the BLINK Beads, a technology that is bound to revolutionize the applications of PCR.
11.04.2023The team working with Alessandra Moretti, Professor of Regenerative Medicine in Cardiovascular Disease, has developed a method for making a sort of "mini-heart" using pluripotent stem cells.
16.03.2023Scientists led by Nobel Laureate Stefan Hell at the Max Planck Institute for Medical Research in Heidelberg have developed a super-resolution microscope with a spatio-temporal precision of one nanometer per millisecond.
15.03.2023Technology developed at the University of Freiburg enables experimental test. The new findings could help to improve the transport of active substances into cells
03.03.2023A research group at Uppsala University has developed a simple and effective artificial blood-brain barrier model that can be used to determine how well antibody-based therapies can enter the brain.
03.03.2023Synthetic hydrogels were shown to provide an effective scaffold for neuronal tissue growth in areas of brain damage, providing a possible approach for brain tissue reconstruction.
02.03.2023The boundaries between biology and technology are becoming blurred. Researchers at Linköping, Lund, and Gothenburg universities in Sweden have successfully grown electrodes in living tissue using the body’s molecules as triggers. The result, published in the journal Science, paves the way for the formation of fully integrated electronic circuits in living organisms.
22.02.2023The enormous amount of data obtained by filming biological processes using a microscope has previously been an obstacle for analyses.
17.02.2023Scientists from the Micro, Nano and Molecular Systems Lab at the Max Planck Institute for Medical Research and the Institute for Molecular Systems Engineering and Advanced Materials at Heidelberg University have created a new technology to assemble matter in 3D.
17.02.2023DNA can help to stimulate bone healing in a localised and targeted manner, for example after a complicated fracture or after severe tissue loss following surgery.
16.02.2023A team led by Prof Claus-Michael Lehr of the Helmholtz Institute for Pharmaceutical Research Saarland (HIPS) has developed a novel human lung cell line that should enable much more accurate predictions of the behavior of active substances or dosage forms in humans than previous systems.
15.02.2023Gattefossé, InProcess-LSP, Knauer, Microfluidics, Skyepharma, and the University of Graz join the RCPE-led European Consortium for Continuous Pharmaceutical Manufacturing (ECCPM) to jointly develop a modular, flexible toolkit to advance industrial-scale production of lipid nanoparticles.
14.02.2023Molecules from mucus can be used to produce synthetic bone graft material and help with the healing of larger bone loss, a new study found.
06.02.2023A collaborative team from the Terasaki Institute for Biomedical Innovation (TIBI) has developed a contact lens prototype that is specifically designed to prevent contact lens-induced dry eye (CLIDE).
27.01.2023The electrical potential across the bacterial cell envelope indicates when bacteria no longer operate as individual cells but as a collective. Researchers at the University of Cologne's Institute for Biological Physics have discovered this connection between the electrical properties and the lifestyle of bacteria.
25.01.2023Fraunhofer researchers have now developed a new method for the production and clinical application of stem-cell-based retinal implants, which could contribute towards the successful treatment of AMD.
15.12.2022Researchers from the Bioengineering and Biomaterials Laboratory of Universidad Católica de Valencia (UCV) have developed a new porous material capable of regenerating bones and preventing infections at the same time.
01.12.2022Wound care by nurses is directly about cleaning, sterile covering, and documentation. Medical and surgical interventions may also be necessary. In this context, wound care also offers potential for the use of technical aids that can help prevent complications.
01.12.2022Wounds – both acute and chronic ones – can have many different causes. They all have in common that they require meticulous care because complications in wound healing can severely reduce both the patients’ health and quality of life. But there is more to modern wound care than just cleaning and bandaging them. Nursing staff and physicians can also access technical aids for this work.
01.12.2022Currently, wound care is limited to either waiting for wounds to heal while keeping them clean and free of infection or using grafts from the patient’s own body to cover larger defects. With the ongoing development tissue engineering and bioprinting, there could be a third option in future: Will we be able to print new tissue directly in the OR to cover surgical wounds?
19.08.2022Researchers at Karolinska Institutet in Sweden and the Swedish University of Agricultural Sciences have discovered that spider silk proteins can be fused to biologically active proteins and be converted into a gel at body temperature.
03.02.2022The waiting time for a donor organ is long nowadays since the need for organs vastly exceeds their availability. But we have possibilities to improve the situation and help as many people as possible to survive despite organ failure: Some organ functions can already be substituted by technology. But medicine is also researching ways to make more organs available for transplant.
03.01.2022The shortage of donor organs is a major global issue. An aging population, a reluctance towards organ donation, and logistical challenges related to organ shipping play an important role in this setting. Machine perfusion can be a way to expand and preserve the donor pool for eligible transplant recipients.
03.01.2022Extracorporeal membrane oxygenation (ECMO) is often a last resort treatment for patients with acute respiratory failure. The method uses an external pump to circulate blood through an artificial lung back into the bloodstream. However, the use of ECMO for long-term support is not possible for patients with chronic respiratory failure.
03.01.2022Patients waiting for a donor organ must have a lot of patience and a bit of luck. Aging and a rise in chronic disease prevalence means the need for donor organs is much greater than the number that is available. To help those who need organ transplants, scientists must create new technologies.
01.12.2021We can replace certain functions of the body with implants nowadays, others we cannot. When it comes to the human senses, we are still quite at the beginning. The technologies and materials we can use are way to coarse compared to our nervous system. But implants can also help us to maintain senses.
29.10.2021Bioengineers and scientists at The University of Texas at Arlington, in collaboration with Austin’s Shani Biotechnologies, LLC, have developed a new noninvasive technology that may help real-time monitoring of key blood parameters, such as hemoglobin, especially in Black patients.
31.08.2021Scientists use the adhesive capabilities of mussels as a model for optimizing hydrogels’ mechanical properties.
29.07.2021An MSU-led team is developing an inexpensive biopolymer dressing to heal injuries like diabetic foot ulcers that affect millions of patients all over the world.
15.06.2021Many modern fitness trackers and smartwatches feature integrated LEDs. The green light emitted, whether continuous or pulsed, penetrates the skin and can be used to measure the wearer's heart rate during physical activity or while at rest.
01.02.2021Therapies need to be carried out with high reliability by trained personal. This will not change in the future. But maybe we will be able to let systems in the patient’s body do some of the work. Some approaches are already aiming to make implants more independent so they will be able to flexibly react to changes. Read more in our Topic of the Month!
01.02.2021In theory, autonomous medical technologies can be used in a diagnostic or therapeutic capacity inside the body under certain conditions. This may not sound like a new invention at first. After all, implantable cardioverter-defibrillators have monitored and fixed abnormal heart rhythm for many years.
27.01.2021Drug research and artificial skin replacement - these are the areas in which tissue engineering and bioprinting are already used today. What else could be possible in the future? We asked Dr. Nadine Nottrodt from Fraunhofer ILT and Prof. Sabine Neuß-Stein from RWTH Aachen University Hospital!
01.12.2020It aims at the production of test systems for drug research and gives patients on the waiting lists for donor organs hope: bioprinting. Thereby biologically functional tissues are printed. But how does that actually work? What are the different bioprinting methods? And can entire organs be printed with it? These and other questions are examined in our Topic of the Month.
01.12.2020How do cells react to certain drugs? And how exactly is new tissue created? This can be analyzed by using bioprinting to embed cells in fine frameworks. However, current methods are often imprecise or too slow to process cells before they are damaged. At the TU Vienna, a high-resolution bioprinting process has now been developed using a new bio-ink.
01.12.2020The big hope of bioprinting is to someday be able to print whole human organs. So far, the process has been limited to testing platforms such as organs-on-a-chip. That's because the actual printing process already poses challenges. Scientists need suitable printing materials that ensure the cell's survival as it undergoes the procedure. The Fraunhofer IGB is researching and analyzing this aspect.
01.09.2020Laboratories have to analyze and interpret an ever-increasing number of samples for research and diagnostic services, generating lots of data in the process. At the same time, labs are required to produce quality results and operate with speed. Processes that could once be managed using laboratory notebooks and isolated systems must become smart in the future to improve lab efficiency.
24.08.2020For the annual MEDICA trade fair, companies from all over the world assemble in Düsseldorf. The Israel Export Institute has been a part of it for the last couple of years. They present medical devices and digital innovations from different Israeli companies at their joint booth.
03.02.2020Collagen is the stuff that holds our bodies together and that houses our cells. In regenerative medicine, it is also the stuff that can be applied to wounds to support healing. However, collagen from animal or human sources has some drawbacks for today’s medicine. This is where rhCollagen from the Israeli company CollPlant comes into play.
03.02.2020Regenerative medicine aims to repair the human body after injuries, accidents or major cancer surgery. Unfortunately, we are still not at a stage where this process can achieve optimal results for every conceivable situation. Having said that, various new methods are on the cusp of breakthrough.
03.02.2020Regenerative medicine aims to replace damage in the body with functional tissue and restore normal function. The first defense for large defects are implants made of hydrogels, designed to promote cell growth. They need their own blood supply, which is a problem when it comes to larger implants because you cannot regulate where and how the blood vessels grow - until now.
15.05.2019New active substances that are suitable for drugs are initially tested in animal experiments. However, the results cannot always be transferred to the human organism. At the Karlsruhe Institute of Technology, Prof. Ute Schepers from vasQlab explains how active substances can be tested in human tissue without endangering human health.
01.02.2019Organ-on-a-chip systems are technically a great enhancement of medical research because they facilitate testing of active ingredients on cell cultures in the chambers of a plastic chip. This replaces animal testing and improves patient safety. That being said, they are not a true-to-life replication of the human body and can only simulate a few functions and activities.