Cancer photoimmunotherapy: novel liquid metal nanoparticles
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Image: A researcher in a pink lab coat works with a pipette while another scientist in a white lab coat supervises the process in a laboratory setting; Copyright: Gustavo Raskosky

Gustavo Raskosky

Superhydrophobic device to model tumor progression

20.09.2024

Rice University bioengineers have harnessed the lotus leaf's unique properties to create a cutting-edge platform for culturing cancer cell clusters. This system offers a new approach to studying tumor progression and metastasis, providing essential insights into cancer biology and treatment.
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Image: Comparison of two tissue sections of a lung, on the left a traditional histological section in pink, on the right a digitized and color-coded tissue section; Copyright: Dr. Yuri Tolkach

Dr. Yuri Tolkach

AI-supported platform improves lung cancer diagnostics

16.09.2024

A new AI-based digital platform, developed by a research team at the University Hospital of Cologne, enables rapid and precise analysis of lung cancer tissue sections. The platform, which is based on advanced algorithms, could significantly improve the quality of diagnostics and provide new insights into the treatment of lung cancer.
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Image: Electrical stimulation in pain therapy on the neck of a woman

Novel electrical stimulation for the treatment of cancer pain

30.08.2024

As part of the international “PAINLESS” project, researchers at the University Medical Center Göttingen (UMG) have developed a non-invasive brain stimulation method for treating pain in cancer patients.
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Image: Researcher in a white coat standing in a laboratory; Copyright: Markus Fischer/Paul Scherrer Institute PSI

Markus Fischer/Paul Scherrer Institute PSI

AI for the precise characterization of breast cancer stages

22.08.2024

A new study by the Paul Scherrer Institute (PSI) and the Massachusetts Institute of Technology (MIT) shows how artificial intelligence (AI) can improve the categorisation of breast cancer stages.
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Image: A researcher places cells in a centrifuge.

Identifying a high-risk biomarker for gastric cancer recurrence risk

16.08.2024

A recent study led by researchers at the Medical University of Vienna has identified the AF1Q gene as a significant biomarker for predicting the risk of gastric cancer relapse. This discovery could enhance personalized treatment strategies and improve survival rates for patients. The study was published in Scientific Reports.
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Image: Person demonstrating the use of a gastrointestinal model to test AI-driven ingestible sensors in a lab setting; Copyright: Khan Lab at USC Viterbi School of Engineering

Khan Lab at USC Viterbi School of Engineering

Smart pills with AI: Advancing gastrointestinal health monitoring

09.08.2024

Researchers at the USC Viterbi School of Engineering have developed advanced ingestible sensors that utilize AI and wearable electronics to provide real-time 3D monitoring of gastrointestinal health. These innovative smart pills can detect stomach gases and track their location within the body, offering potential for early disease detection.
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Image: Miniature, implantable LED device on the palm of a hand; Copyright: University of Notre Dame

University of Notre Dame

LED Implant: A new approach to deep-seated cancer treatment

08.08.2024

A team of engineers and scientists at the University of Notre Dame has developed a wireless LED device that can be implanted to treat deep-seated cancers. This device, when combined with a light-sensitive dye, not only destroys cancer cells but also activates the immune system to target the cancer. The research findings were published in Photodiagnosis and Photodynamic Therapy.
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Image: Researchers examine DNA samples and discuss biomedical treatment

Blood tests: Tracking down cancer with circulating DNA

30.07.2024

Liquid biopsies in the form of blood tests offer the possibility of analyzing circulating free DNA in the blood and thus improving cancer therapies. The advantage of diagnostics using blood tests is that they can help to detect tumors at an early stage and efficiently monitor the progression of cancer.
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Image: Person lying on a treatment table while an ultrasound is being performed

Autonomous ultrasound: relieving the burden of everyday medical care

26.07.2024

Autonomous robotic ultrasound systems can perform routine examinations and support doctors in the operating room. Prof. Nassir Navab from the Technical University of Munich (TUM) is researching these technologies and demonstrating their potential for everyday medical practice.
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Image: Close-up of the heads of two people performing a surgical procedure; Copyright: Jun-Prof. Benjamin Wolf/University of Leipzig

Jun-Prof. Benjamin Wolf/University of Leipzig

TMMR study shows success in cervical cancer treatment

16.07.2024

Cervical cancer is the fourth most common malignant tumor disease in women worldwide. New research results from a comparative study lasting almost ten years show that total mesometrial resection (TMMR) practiced at Leipzig University Medicine has significant advantages over standard treatment.
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Image: Simplified model of the low-field magnetic resonance tomograph; Copyright: Max Planck Institute for Biological Cybernetics

Max Planck Institute for Biological Cybernetics

Cost-efficient MRI diagnostics for the Global South

10.07.2024

Researchers at the Max Planck Institute for Biological Cybernetics have developed a new method for cost-efficient medical imaging. This method combines low-field magnetic resonance imaging (MRI) with hyperpolarization and artificial intelligence to improve image quality.
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Image: A person at the left edge of the picture looks at monitors displaying radiological image data from CT and MRI; Copyright: Karin Kaiser/MHH

Karin Kaiser/MHH

Automated image analysis improves cancer diagnoses in pediatric radiology

03.07.2024

Hannover Medical School (MHH) is leading the RACOON-RESCUE project, which aims to open up new diagnostic possibilities for non-Hodgkin's lymphomas in children and adolescents with the help of automated image data analysis from CT and MRI. The project, led by Prof. Diane Renz, aims to determine disease stages more precisely and optimize therapy follow-up.
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Image: Two women in specialist medical clothing operate a mammography system; Copyright: lakobchuk

lakobchuk

Mammography: Transpara supports early breast cancer detection with AI

02.07.2024

The introduction of artificial intelligence (AI) into medical diagnostics has brought about transformative changes, particularly in the early detection of breast cancer. One innovative solution: Transpara.
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Image: Laboratory procedure for the cryopreservation of ovarian tissue; Copyright: Alessandro Winkler University Hospital Bonn (UKB)

Alessandro Winkler University Hospital Bonn (UKB)

First successful birth after vitrification of ovarian tissue in Europe

12.06.2024

A team at the University Hospital Bonn (UKB) has established a modern method for the cryopreservation of ovarian tissue known as vitrification. This technique is used to preserve fertility before cancer therapies.
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Image: Scientist pipettes cells into a test tube in a a laboratory setting

New findings on short-term cultivated CAR T cells in cancer treatment

28.05.2024

Chimeric Antigen Receptor T (CAR T) cells are a breakthrough in immunotherapy, offering hope for blood cancer patients who have exhausted other options. These genetically modified cells are designed to attack cancer cells by recognizing specific antigens. The therapy has shown promise, particularly in treating B-cell leukemias and lymphomas.
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Image: blue prototype for MRI-integrated proton therapy; Copyright: K. Lassig / UKD

K. Lassig / UKD

MRiPT technology: prototype for new approaches in cancer treatment

30.04.2024

MRI-integrated proton therapy (MRiPT) marks a significant advance in cancer treatment by increasing the precision of radiation treatment. In an interview with MEDICA.de, Prof. Aswin Hoffmann presents current technological challenges and highlights the potential benefits of real-time MRI imaging for proton therapy.
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Image: A Fraunhofer IWS laboratory device is held by a person in blue gloves; Copyright: minkus-images.de/Fraunhofer IWS

minkus-images.de/Fraunhofer IWS

Insights into the development of metastases with miniature laboratories

22.04.2024

New developments at the Fraunhofer Institute for Material and Beam Technology IWS and partners enable improved research possibilities for cancer therapy using microphysiological systems.
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Image: Two researchers are standing side by side, smiling for a photo in a bright corridor with windows, likely within a university or research facility; Copyright: CHUM

CHUM

Liver cancer treatment: Utilizing magnetic field-guided microrobots

12.04.2024

A new medical technique utilizing magnet-guided microrobots for treating liver tumors has been developed by a Canadian research team, offering a potential new approach in oncology.
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Image: A close-up view of a person examining a patient's skin with a dermatoscope, a specialized device used for inspecting skin lesions that can be indicative of conditions like melanoma

Enhancing melanoma detection in primary care with AI

08.04.2024

In a study by Linköping University, an AI-based mobile app has shown high precision in diagnosing skin melanoma, offering new hope for early detection. This research marks a significant step forward in utilizing artificial intelligence (AI) for health diagnostics in primary care settings.
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Image: A woman lies on her back covered with a hairnet and is examined with a measuring device on her facial skin.

Raman sensor system: non-invasive monitoring with wide-ranging applications

04.04.2024

The Raman sensor system opens new monitoring possibilities by precisely measuring the concentration of carotenoids in the skin - a potential indicator of health. This technology offers a non-invasive insight into dietary habits and health status, with the potential to monitor the effectiveness of chemotherapies.
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Image: An image in white and green visualizes the procedure of this new AI model; Copyright: Ida Häggström

Ida Häggström

Harnessing AI for medical imaging of lymphatic cancer cases

22.03.2024

Researchers at Chalmers University of Technology unveil an AI model capable of detecting lymphatic cancer with 90 percent accuracy, improving medical imaging analysis. This new technology promises to enhance diagnostic capabilities and streamline patient care.
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Image: This image shows two screens. The one of the right shows the word AI and the left some text. On the right side, there is a man looking at the screens.

Prototype applies AI to advance colorectal diagnosis

15.03.2024

Portuguese researchers from the Institute for Systems and Computer Engineering, Technology and Science (INESC TEC) and the IMP Diagnostics Molecular & Anatomic Pathology laboratory have unveiled the world's first prototype applying Artificial Intelligence (AI) to colorectal diagnosis.
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The photo shows a hand holding a silver, tubular device which improves imaging and detecting gastrointestinal cancer; Copyright: J. Crowley

J. Crowley

Imaging device for early gastrointestinal cancer detection

01.03.2024

Gastrointestinal cancers (GCs) pose a significant health challenge worldwide, with early detection being crucial for effective treatment and improved survival rates. To address this need, scientists have developed a new imaging device aimed at enhancing the accuracy and accessibility of GC screening programs.
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Image: A woman with cancer sits in a wheelchair and scrolls through information on a tablet.

Overcoming fatigue: An app for greater quality of life

20.02.2024

Cancer patients often suffer from fatigue syndrome as a side effect. This makes it difficult to cope with everyday life and is usually treated with physiotherapy and behavioral therapy. In the future, an anti-fatigue app should enable treatment to be individually tailored to the person.
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Image: Two doctors are holding an infrared temperature thermometer gun, which can take thermal infrared images of breasts analysing possible breast cancer tumors; Copyright: Nazarbayev University

Nazarbayev University

Early breast cancer detection with AI-powered tool

13.02.2024

In a new development, NTU Singapore researchers have introduced PINN, a state-of-the-art computer program that utilizes AI and heat-imaging technology to detect early breast cancer swiftly and accurately.
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Image: Close-up and 3D illustration of cream-colored molecules on a black background; Copyright: Determined

Determined

A sugar analysis could reveal different types of cancer

22.12.2023

In the future, a little saliva may be enough to detect an incipient cancer. Researchers at the University of Gothenburg have developed an effective way to interpret the changes in sugar molecules that occur in cancer cells.
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Image: AI-based segmentation of melanoma metastases in a tumor; Copyright: USZ

USZ

Understanding and fighting tumors better with new algorithms

21.12.2023

The University Hospital Zurich, the University of Zurich and the diagnostics company Roche are expanding their collaboration in cancer research. In the fully digitalized Morphomolecular Pathology Laboratory, they are developing algorithms that can further improve the effectiveness of immunotherapies.
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Image: Blue and white logo from the EU consortium CERTAINTY; Copyright: Fraunhofer-Gesellschaft

Fraunhofer-Gesellschaft

CERTAINTY: virtual twin for improved cancer immunotherapies

20.12.2023

Together with partners from science, industry and the healthcare sector, the project team led by the Fraunhofer Institute for Cell Therapy and Immunology IZI aims to develop a virtual twin that will improve treatment with personalized cancer immunotherapies in the future.
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Image: Radiologist does mammograms for woman to check for breast cancer; Copyright: astakhovyaroslav

astakhovyaroslav

AI can identify women with high risk of breast cancer screenings

13.12.2023

The use of AI makes it possible for women with a high risk of breast cancer to be identified in mammography screening examinations so that the cancer can be caught earlier. An international research group led from Karolinska Institutet in Sweden can now show that the method is effective in different European countries.
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Image: A sample is placed in a centrifuge by a person wearing personal protective clothing; Copyright: microgen

microgen

TissueGrinder: Improved cell analyses via enhanced-quality sample preparation

07.12.2023

A new method for examining tissue samples could change the way we diagnose and treat cancer. Researchers at the Max Planck and Fraunhofer IPA have developed an automated system based on the principle of enzyme-free tissue processing and the mechanical deformability of individual cells.
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Image: Anatomical model of human pancreatitis; Copyright: JoPanwatD

JoPanwatD

Pancreas: nanoparticles for optimized cancer therapy

23.11.2023

Researchers from Göttingen and Karlsruhe have developed a new treatment approach for pancreatic cancer. The innovative method promises to be able to treat the disease in a more targeted way and with fewer side effects in the future. The therapy is now to be optimized for clinical application as quickly as possible.
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Image: Rebecca Richards-Kortum smiles at the camera in a lab; Copyright: Brandon Martin/Rice University

Brandon Martin/Rice University

Affordable global health technologies for early cancer detection

06.11.2023

A Rice University-led collaboration from three continents has won up to a five-year grant from the National Institutes of Health to establish a premier research center in the Texas Medical Center to develop affordable, effective point-of-care (POC) technologies that improve early cancer detection in low-resource settings in the United States and other countries.
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Image: A person wearing white disposable gloves examines a woman's back with a magnifying glass; Copyright: Medical University of Vienna

Medical University of Vienna

Skin cancer diagnoses using AI are as reliable as those made by medical experts

02.11.2023

An Austrian-Australian research team led by dermatologist Harald Kittler from MedUni Vienna investigated the extent to which diagnosis and therapy of pigmented skin lesions benefit from it in a realistic clinical scenario.
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Image: Image of fluorescently labeled nanoparticles (pink) in human colon cancer cells (green) 24 hours after addition to cell culture; Copyright: umg/Dr. Dolma Choezom

umg/Dr. Dolma Choezom

Project CANACO: better imaging-based and targeted therapy of colon cancer

01.11.2023

The University Medical Center Göttingen (UMG) is coordinating the development of a new nanoparticle-based method for the personalized therapy of patients suffering from colon cancer.
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Image: The MinION device connected to a computer. The screen shows data from the evaluation; Copyright: Oxford Nanopore

Oxford Nanopore

Nanopore sequencing and DNA barcoding method gives hope of personalised medicine

03.10.2023

With the ability to map dozens of biomarkers at once, a new method could transform testing for conditions including heart disease and cancer.
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Image: Mammography snapshot of a patient's breasts on the monitor with mammography test; Copyright: ORION_production

ORION_production

AI model to improve accuracy of breast cancer tumor removal

02.10.2023

A new clinical and research partnership has created an AI model that can predict whether or not cancerous tissue has been fully removed from the body during breast cancer surgery.
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Image: Dr. Marina Dziuba in the laboratory with bacterial cultures to produce magnetic nanoparticles; Copyright: Christian Wißler/UBT

Christian Wißler/UBT

EXIST funding for bacterial magnetic nanoparticles

28.09.2023

BioMagnetix uses bacterial magnetic nanoparticles as innovative materials for biomedical applications. The founding team aims to develop and continuously improve high-quality and highly functional magnetic nanoparticles for imaging techniques and therapeutic purposes, such as cancer treatment.
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Image: Cellular Cartography - Charting the Sizes and Abundance of Our Body's Cells Reveals Mathematical Order Underlying Life; Copyright: MPIMIS

MPIMIS

Cellular cartography: sizes and abundance revealed

27.09.2023

An international team of scientists has created the first comprehensive index of human cells, mapping the sizes and abundance of all cell types across the entire body.
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wosunan

Microrobots: opportunities for cancer treatment and wound healing

18.09.2023

A group of researchers at the Technical University of Munich (TUM) has developed the world’s first microrobot (“microbot”) capable of navigating within groups of cells and stimulating individual cells.
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Image: Woman with blonde hair and a light blue blouse smiles at the camera. There are trees in the background; Copyright: Karolinska Institutet

Karolinska Institutet

Breast cancer: more cases detected with the help of AI

15.09.2023

One radiologist supported by AI detected more cases of breast cancer in screening mammography than two radiologists working together, reports the ScreenTrustCAD study from Karolinska Institutet in The Lancet Digital Health.
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Image: Blue immune cells wandering from bottom to top on a black background; Copyright: Jonna Alanko/Science Immunology

Jonna Alanko/Science Immunology

How immune cells migrate

11.09.2023

When fighting disease, our immune cells need to reach their target quickly. Researchers at the Institute of Science and Technology Austria (ISTA) now discovered that immune cells actively generate their own guidance system to navigate through complex environments.
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Image: A bald man in a white coat stands in a laboratory and looks over at other people; Copyright: Joakim Palmqvist

Joakim Palmqvist

Advanced biosensors to detect tumors, viruses and bacterial diseases

06.09.2023

Linnaeus University is partnering with industry and healthcare to develop advanced biosensors, investing SEK 35 million in a project aimed at faster and cost-effective diagnoses of aggressive lung cancer, viral, and bacterial diseases, potentially enabling self-testing at home.
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Image: Close-up of two hands in blue gloves preparing a dose of vaccine by syringe; Copyright: Beate Armbruster/University Hospital of Tuebingen

Beate Armbruster/University Hospital of Tuebingen

Protection for cancer patients

05.09.2023

Tübingen T-cell activator offers protection against coronaviruses in immunocompromised patients
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Image: Two men and a woman in white coats work in a laboratory with reaction vessels; Copyright: Karin Kaiser / MHH

Karin Kaiser / MHH

More impact against cancer

04.09.2023

MHH molecular physician Professor Dr. Dr. Schambach wants to use genetically modified natural killer cells to find new therapeutic options against three particularly malignant cancers. The EU is funding the project with 3.8 million euros
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Image: Illustration of a protein structure with its amino acid complexes; Copyright: Kateryna Maksymenko

Kateryna Maksymenko

Innovative computational approach helps design proteins for cancer treatment

31.08.2023

A joint team of researchers from the Max Planck Institute for Biology Tübingen and the University Hospital Tübingen has now developed and tested a new computational method to greatly speed up the necessary energy calculations.
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Image: Close-up of microtiter plates that are filled with several pipettes; Copyright: LMU

LMU

Immunotherapy: Antibody kit to fight tumors

25.08.2023

A new study highlights the potential of artificial DNA structures that, when fitted with antibodies, instruct the immune system to specifically target cancerous cells.
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Image: Hands of a surgeon on the control console of a surgical robot; Copyright: Gerain0812

Gerain0812

Sensor-controlled precision: the future of surgical tumor removal

22.08.2023

The complete removal of malignant tumors is a decisive factor for the success of cancer treatment. Until now, the tissue examinations required for this have been time-consuming. In the future, sensor-based methods could come into play to help surgeons detect tumor boundaries more accurately and thus perform a more precise operation.
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Image: A doctor palpates a patient's lymph nodes in the examination room; Copyright: Wavebreakmedia

Wavebreakmedia

Study: Fluidity predicts aggressiveness of cancerous tumours

17.08.2023

Researchers discovered that the consistency of a tumor can have a decisive influence on the further course of cancer.
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Image: A mammogram image of a breast on a screen; Copyright: ORION_production

ORION_production

AI-supported mammography screening is found to be safe

11.08.2023

Mammography screening supported by artificial intelligence (AI) is a safe alternative to today’s conventional double reading by radiologists and can reduce heavy workloads for doctors.
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Image:Upon irradiation by near infra-red light, Anti-PD-L1 specifically binds to the cancer cell, while immunostimulants activate T and dendritic cells; Copyright: Eijiro Miyako from JAIST

Eijiro Miyako from JAIST

Cancer photoimmunotherapy: novel liquid metal nanoparticles

10.08.2023

JAIST researchers create liquid metal nanoparticles (PEG-IMIQ-LM) for cancer treatment, merging photothermal therapy and immunotherapy. Disintegration delivers immunomodulants and tracks cancer cells in real-time. Immune checkpoint inhibitor enhances cancer removal. Promising for future cancer theranostics, with clinical trials anticipated in a decade.
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Image: A doctor examines a patient's left shoulder for skin cancer; Copyright: Inside Creative House/Shutterstock

Inside Creative House/Shutterstock

Skin cancer diagnosis: reinforcement learning for improved performance of AI

02.08.2023

An international research team led by Harald Kittler of MedUni Vienna has now explored a learning method in which greater accuracy in AI results can be achieved by incorporating human decision-making criteria.
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Image: Michal Rawlik (left), first author of the publication, and Marco Stampanoni pose at a table in an office space; Copyright: Paul Scherrer Institut

Paul Scherrer Institut

Improvement of the CT: earlier detection of breast cancer

26.07.2023

A team of researchers from the Paul Scherrer Institute PSI and ETH Zurich, together with the Baden Cantonal Hospital (KSB) and the University Hospital Zurich (USZ), has succeeded in refining mammography, x-ray imaging technique used to detect tumours in their early stages, to produce considerably more reliable results and be less unpleasant for the patient.
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Image: A mammologist feels the lymph nodes in a patient's armpits; Copyright: Zinkevych_D

Zinkevych_D

Breast cancer: international expert recommendations on removal of lymph nodes

24.07.2023

Researchers from Heidelberg University Hospital and the University of Lucerne as well as international scientists, patient representatives and European cancer societies have pooled scientific data and their expert knowledge on the surgical management of lymph nodes in breast cancer.
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Image: Image showing the preparation of hydrogels that enhance the viability of NK cells; Copyright: KIMM

KIMM

3D bioprinting technology to be used for removing cancer cells

14.07.2023

KIMM develops the world’s first 3D bioprinting technology that enhances the function of NK immune cells. The new technology is expected to improve effectiveness of cancer treatment.
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Image: Man in a dark blue jacket and shirt, Prof. Jakob N. Kather, stands in a corridor and smiles at the camera; Copyright: EKFZ

EKFZ

AI against bowel cancer: research project DECADE

12.07.2023

The DECADE research project is the first to use swarm learning in cancer research. The German Cancer Aid is funding the joint project of several university hospitals with around 1.5 million euros.
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Image: Woman in a laboratory collecting blood samples; Copyright: Prostock-studio

Prostock-studio

Molecular tumor profiling: blood test to determine the optimal cancer therapy

11.07.2023

If a tumor is diagnosed, tissue samples are usually investigated to determine the molecular tumor profile for personalized cancer treatment. However, tissue biopsy cannot be performed in all affected individuals. Therefore, the University Hospital Zurich has licensed a liquid biopsy for the analysis of more than 300 genes and offers this test as a modern diagnostic method to tumor patients.
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rawf8

Improved cancer therapy: TimeTeller shows what makes the body tick

06.07.2023

Using the internal clock to optimize chemotherapies in cancer treatment - that is the goal of the start-up TimeTeller. If the drugs are administered at the ideal time of day for chemotherapy, it can reduce side effects and improve the effect. TimeTeller has developed a method for determining the internal clock to make this possible.
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Image: Portrait photo of a blond woman with blue eyes in a white blouse; Copyright: University of Gothenburg

University of Gothenburg

Skin cancer: curettage and cryosurgery effective for basal cell carcinoma

30.06.2023

The number of cases of skin cancer is continuing to rise sharply, in Sweden and internationally, involving high costs for a healthcare economy that is already under severe strain in many places. Eva Backman and her team studied the efficacy of treatment options.
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Image: Two young men in white coats, Dr. Jonas Hall and Dr. Niklas Klümper, pose in front of the camera in a research complex; Copyright: University Hospital of Bonn (UKB)

University Hospital of Bonn (UKB)

Metastatic renal cell carcinoma: improved prediction of therapy response

29.06.2023

The study demonstrates a significant improvement in predicting the response to therapy in metastatic renal cell carcinoma by incorporating the level of inflammation, which was assessed using two straightforward blood parameters, alongside the conventional imaging-based approach.
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Image: Two men and three women pose in white coats in a laboratory; Copyright: Universidad de Barcelona

Universidad de Barcelona

New biomarkers of non-small cell lung cancer discovered

27.06.2023

Researchers of the University of Barcelona and the Institute of Bioengineering of Catalonia (IBEC) have identified new biomarkers for non-small cell lung cancer, the most common lung cancer.
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Image: Fluorine-18-labelled folate PET/CT 3D fusion image of a rat subject with a glioma visible in the central region of the brain; Copyright: Maxwell Miner

Maxwell Miner

PET imaging: discovery can help detect brain tumours

22.06.2023

Folate-based radiopharmaceuticals can be used in positron emission tomography (PET) imaging to detect folate receptors in brain tumours. The discovery of folate receptors and their exploitation potential with respect to brain tumours is a new and significant finding in the field.
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Image: Two women with loose hair and colorful blazers pose in front of an institute; Copyright: Gregor Hübl / Universität Bonn

Gregor Hübl / Universität Bonn

Researching organoids: two new Argelander Professors at the University of Bonn

21.06.2023

Two new assistant professors at the University of Bonn are setting out to develop “mini-organs” in order to study metabolic and disease mechanisms.
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Image: Nils Wagner, a man with brown hair in a T-shirt, sits at a computer screen on which codes are displayed; Copyright: Dennis Gankin / TUM

Dennis Gankin / TUM

Algorithm helps search for the cause of hereditary diseases

07.06.2023

A Munich research team has developed an algorithm that predicts the effects of genetic mutations on RNA formation six times more precisely than previous models.
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Image: Visualization of a radioactive preparation that docks onto blood cells in a bloodstream; Copyright: B. Schröder/HZDR

B. Schröder/HZDR

Cancer: new theranostic for imaging and treatment

01.06.2023

Thanks to the radiation they emit, radioactive compounds are suited both to imaging and treating cancers. By appropriately combining them in novel, so-called radionuclide theranostics, both applications can be dovetailed.
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Image: Two men and a woman in a doctor's coat: the woman is holding a map of the world and the two men are pointing to Germany and Uzbekistan with a pen; Copyright: Karin Kaiser / MHH

Karin Kaiser / MHH

With ultrasound against liver cancer

24.05.2023

The Hannover Medical School (MHH) enters into a clinic partnership with Uzbekistan and supports with a training program for sonography diagnostics of hepatocellular carcinoma (HCC).
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Image: A computer that evaluates stool samples using bioinformatic methods; Copyright: Anna Schroll/Leibniz-HKI

Anna Schroll/Leibniz-HKI

Model shows intestinal bacteria influence growth of fungi

22.05.2023

The bacteria present in the intestine provide information about the quantities of fungi of the potentially disease-causing Candida genus.
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Image: A man in a gray jacket and white shirt, Miroslaw Bober, smiles at the camera; Copyright: University of Surrey

University of Surrey

UK AI world leader in identifying location and expression of proteins

18.05.2023

A new advanced artificial intelligence (AI) system has shown world-leading accuracy and speed in identifying protein patterns within individual cells.
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Image: Microscopic image of bone-marrow cells of a multiple myeloma patient.; Copyright: Berend Snijder Lab / ETH Zurich

Berend Snijder Lab / ETH Zurich

How to fight blood cancer more effectively

05.05.2023

Despite approved treatments being available, multiple myeloma remains incurable. But researchers at ETH Zurich and University Hospital Zurich set out to improve treatment outcomes by testing hundreds of existing therapeutics outside the body to predict their effectiveness.
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Image: 3D render of the tibias treated with the current clinical treatment option chemotherapeutics or treated with chemotherapeutics plus gene therapy; Copyright: UCD Research and Innovation

UCD Research and Innovation

Novel combination of therapies may provide new treatment option for bone cancer

03.05.2023

New research has identified a potential therapeutic target and developed a unique delivery system to treat osteosarcoma, a bone cancer that primarily affects children and adolescents.
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Image: Medical samples are treated with a plasma pen; Copyright: INP

INP

Plasma against precancerous skin lesions: EU funds international doctoral candidates network

24.04.2023

Under the leadership of the Leibniz Institute for Plasma Science and Technology (INP), the international doctoral candidates network PlasmACT is investigating the use of medical gas plasma technology as a treatment method.
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Image: Schematic illustration: The proposed robotic bronchoscope system for navigation-assisted intervention; Copyright: Cyborg and Bionic Systems

Cyborg and Bionic Systems

Novel robotic bronchoscope system for navigation and biopsy of pulmonary lesions

19.04.2023

A novel robotic bronchoscope system can non-intrusively access the area of interest within the lung for minimally invasive pulmonary lesions sampling, the gold standard of lung cancer diagnoses.
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Image: Johannes Karges smiles for the camera in a light blue shirt and dark blue jacket. In the background is a green area; Copyright: RUB, Marquard

RUB, Marquard

Ultrasound activates anticancer agent

14.04.2023

Chemotherapy treatments produce strong side effects. A new agent that accumulates in the tumour tissue and is activated there by ultrasound waves does not have this problem.
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Image: Dr Ioana Slabu and Benedict Bauer with the nanomodified stent fot he camera; Copyright: Peter Winandy

Peter Winandy

Novel technology for hollow organ tumour therapy

10.04.2023

Ioana Slabu from the Institute of Applied Medical Technology and Benedict Bauer from the Institut für Textiltechnik of RWTH Aachen University have developed a novel technology for the therapy of hollow organ tumours, which was awarded second place in the RWTH Innovation Award.
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Image: ENT doctor or dentist with a medical instrument examining the oral cavity; Copyright: YuriArcursPeopleimages

ONWARD Medical NV

PANDORA test could pave the way for better oral cancer detection

06.04.2023

Surrey scientists have developed a proof-of-concept test called PANDORA that was shown to be over 92% accurate at identifying patients with oral squamous cell carcinoma (OSCC). The test was also shown to be more than 80% accurate at identifying patients with pre-cancer or oral epithelial dysplasia (OED).
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Image: Three men and a woman in white lab coats pose for the camera in a laboratory; Copyright: Universidad de Barcelona

Universidad de Barcelona

Microfluidics physics-based device to predict cancer therapy response

06.04.2023

A team of experts has designed a microfluidic device called microfluidic dynamic BH3 profiling (μDBP) that predicts the effectiveness of cancer treatment quickly and automatically.
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Image: Study co-authors in white coats (from left) Caleb Bashor, Antonios Mikos and Letitia Chim; Copyright: Gustavo Raskosky/Rice University

Gustavo Raskosky/Rice University

Upgraded tumor model optimizes search for cancer therapies

27.03.2023

Rice University researchers developed an upgraded tumor model that houses osteosarcoma cells beside immune cells known as macrophages inside a three-dimensional structure engineered to mimic bone. Using the model, bioengineer Antonios Mikos and collaborators found that the body’s immune response can make tumor cells more resistant to chemotherapy.
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Image: Close-up of a pregnancy belly, the woman is holding her hand on her belly; Copyright: Karin Kaiser/MHH.

Karin Kaiser/MHH.

Better care for pregnant women with precancerous cervical cancer

23.03.2023

Preliminary stages of cervical cancer occur mainly in women between 25 and 35 years of age. The main risk factor for developing cervical cancer is the human papillomavirus (HPV). Surgery is the treatment of choice.
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Image: A woman with blond hair in a white coat sits in a laboratory and works with Petri dishes; Copyright: University of the West of Scotland

University of the West of Scotland

Radiology: Research could improve cancer treatment

22.03.2023

UWS School of Computing Engineering and Physical Sciences are developing breakthrough investigations into advanced radiation treatment technique, after receiving funding from Cancer Research UK RadNet – the charity's radiation research network.
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Image: Close-up of a female hand holding the orange ribbon symbolizing the fight against leukemia; Copyright: JoPanwatD

JoPanwatD

AI finds targets for CAR-T cell therapy against acute myeloid leukemia

20.03.2023

Unlike other forms of blood cancer, acute myeloid leukemia (AML) cannot currently be treated with CAR-T cell immunotherapy. The reason is that specific molecular targets with which certain immune cells could specifically target AML cells are lacking, which would permit the immune system to attack cancer.
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Image: Closeup of ultrasound examination of abdominal cavity, stomach and heart with sonography sensor; Copyright: Natabuena

Natabuena

Ultrasound method could lead to easier disease diagnosis in body tissue

17.03.2023

A new ultrasound method that can measure the level of tension in human tissue for the first time - a key indicator of disease - has been developed by researchers from the University of Sheffield.
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Image: Medical research Close-up of a microplate; Copyright: manjurulhaque

manjurulhaque

RIANA: Viennese start-up develops novel, precise anti-cancer drugs

14.03.2023

The technological basis is a proprietary platform technology for the discovery of drugs that target cancer-causing protein-protein interactions (PPIs).
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Image: Microscopic image: Mouse lymph nodes with colored fluorescent markers; Copyright: AG Hoelzel/UKB

AG Hoelzel/UKB

Artificial intelligence to help tumor immunology

09.03.2023

Developing methods to predict the nature of the tumor microenvironment is the goal of researchers from the Clusters of Excellence ImmunoSensation2 and the Hausdorff Center for Mathematics (HCM) led by Prof. Kevin Thurley at the University of Bonn.
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Image: Two men in white laboratory clothing are working on new quantum light modules; Copyright: FBH/P. Immerz

FBH/P. Immerz

Entangled photon pairs to help fighting cancer

06.03.2023

The recently launched QEED project aims to significantly reduce measurement time in clinical cancer diagnostics by developing a spectrally resolved imaging technique based on entangled photon pairs. FBH scientists will develop the required diode lasers and quantum light modules.
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Image: Two men and a woman stand in front of a building and smile for the camera; Copyright: RUB, Marquard

RUB, Marquard

AI with infrared imaging enables precise colon cancer diagnostics

23.02.2023

Researchers at the Centre for Protein Diagnostics PRODI at Ruhr University Bochum, Germany, are using artificial intelligence in combination with infrared imaging to optimally tailor colon cancer therapy to individual patients.
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Image: Dr Anke Katharina Bergmann in a white coat, holding a tablet, is standing in front of a virtual map of Europe; Copyright: Karin Kaiser / MHH, Freepik.com

Karin Kaiser / MHH, Freepik.com

MHH leads EU large-scale project for personalized cancer care

26.01.2023

CAN.HEAL aims to expand the available innovations in cancer prevention, diagnosis and treatment in the Member States in order to improve care for all patients in the EU. The project focuses on measures of personalized medicine. Genomics is an important cornerstone for this.
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Image: Three men poses for the camera, Dr Chiang Chi-leung and Professor Albert Chan Chi-yan. (Right) patient Mr Wan Ying-keung.; Copyright: The University of Hong Kong

The University of Hong Kong

'Reduce and Remove': new treatment strategy for locally advanced liver cancer

19.01.2023

A pioneering phase II clinical study on tri-modality therapy (START-FIT), conducted by the Department of Surgery and Department of Clinical Oncology, School of Clinical Medicine, LKS Faculty of Medicine of the University of Hong Kong (HKUMed), has found that nearly 50% of patients with inoperable locally advanced liver cancer, can be cured through such an innovative approach.
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Image: Representation of a uterus as a hologram. The hologram hovers over two cupped hands; Copyright: Medical University of Vienna

Medical University of Vienna

Locally advanced cervical cancer: Better odds using personalized brachytherapy

17.01.2023

For the first time, a study conducted by a research group at the Comprehensive Cancer Centre Vienna of MedUni Vienna and Vienna General Hospital using data from the multicentre EMBRACE-I trial demonstrated the superiority of a targeted approach in brachytherapy.
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Image: Two men and two women are standing in a laboratory and examining a small apparatus (microphysiological system); Copyright: Amac Garbe/Fraunhofer IWS

Amac Garbe/Fraunhofer IWS

Radioactive substances fight cancer in the mini-lab

13.01.2023

Two Dresden research institutes want to reduce the number of animal experiments in radiopharmaceutical research with a new idea.
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Image: Two doctors in scrubs look at a screen during an AI-assisted colonoscopy; Copyright: Universitätsklinikum Bonn (UKB)

Universitätsklinikum Bonn (UKB)

AI improves colorectal cancer screening in Lynch syndrome

10.01.2023

Researchers at the National Center for Hereditary Tumor Diseases (NZET) at Bonn University Hospital (UKB) have now found that artificial intelligence (AI) can improve the effectiveness of colonoscopy in the presence of Lynch syndrome.
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Image: Small moldecules - illustration in orange; Copyright: Aalto University

Aalto University

Gaining unprecedented view of small molecules by machine learning

06.01.2023

A new tool to identify small molecules offers benefits for diagnostics, drug discovery and fundamental research. A new machine learning model will help scientists identify small molecules, with applications in medicine, drug discovery and environmental chemistry.
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Image: Oncologist looking at patients x-ray photos and making notes in red notebook; Copyright: sofiiashunkina

sofiiashunkina

Complete package for minimally invasive tumor therapy

04.01.2023

License agreement and joint development: Fraunhofer MEVIS commences cooperation with Israeli partner for worldwide use of innovative software technology in ultrasound-aided tumor ablation.
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Image: Scientist works with medical test tube to analyze green liquid; Copyright: DC_Studio

DC_Studio

Diagnosing breast cancer through liquid biopsy

22.09.2022

Breast cancer diagnosis usually includes invasive testing with tissue biopsies. The samples have to be extracted from the cancerous tissue or cells. To make the process easier on the patients, the project LIBIMEDOTS is currently developing a different approach with liquid biopsy technology.
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Image: Thierry Nordmann (left) & Lisa Schweizer are standing in the lab, each with a pipette in hand and a microtiter plate in front of them; Copyright: Susanne Vondenbusch-Teetz, MPI for Biochemistry

Susanne Vondenbusch-Teetz, MPI for Biochemistry

Deep Visual Proteomics: tracking down cancer

08.09.2022

Proteins are frequently called the building blocks of life because they are found everywhere, including in our cells. This makes them an important factor when it comes to diseases. As a result, mapping the protein landscape can be a crucial ally in the fight against diseases. Now, a German-Danish team has developed a method that provides researchers with unprecedented insights into cancer.
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Image: Two male researchers analyzing data sets on a computer screen; Copyright: Felix Petermann | MDC

Felix Petermann | MDC

Project "ikarus" provides new insights for cancer research

01.08.2022

Artificial intelligence (AI) is about to become a game changer, especially in diagnostics. However, there are still limits to the use of AI. Dr. Altuna Akalin had to recognize this as well. The head of the Max Delbrück Center's (MDC) technology platform for "Bioinformatics and Omics Data Science" developed "ikarus" with his team.
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Image: Two men are sitting in front of a laptop computer and are talking about an image on the screen - Josch Konstantin Pauling, Nikolai Köhler; Copytight: LipiTUM

LipiTUM

MoSBi: Algorithm identifies disease subtypes

01.08.2022

Doctors have always used symptoms, imaging, and laboratory data to define and diagnose diseases, but at times it is simply not enough: while patients may have the same illness, it may exhibit different changes at the molecular level. A team from the Technical University of Munich has developed the so-called MoSBi algorithm and makes it available to researchers to identify molecular differences.
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Image: Two drops of water on a screen that shows a pattern of colored bars; Copyright: ktsimage

ktsimage

Big Data in genetics: reaching diagnosis through heaps of data

01.08.2022

Most laboratory tests only produce small amounts of data that are already sufficient for successful diagnosis. It becomes more difficult with genetic questions: whether it is about a genetic disease or the properties of tumors, there are large amounts of data that must be considered. Both research and medicine need help to identify the connections and patterns in the data to find a diagnosis.
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Image: Professor Dr Peter Hillemanns and PD Dr Matthias Jentschke with the HPV self-tests; Copyright: Karin Kaiser/MHH

Karin Kaiser/MHH

Prevention of cervical cancer with HPV self-testing

28.10.2021

Cervical cancer is one of the most common diseases of the female reproductive organs. Human papilloma viruses are almost always responsible for cervical cancer and the corresponding precancerous lesions. As part of the statutory preventive medical check-up, women from the age of 20 can have a cell smear taken from the cervix once a year, the so-called Pap test, to detect cell changes.
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Image: Two surgeons are standing at the control console of an OR device; Copyright: Christian Morawe/Universitätsmedizin Magdeburg

Christian Morawe/Universitätsmedizin Magdeburg

Histotripsy: fighting tumors with microbubbles

08.09.2021

Focused ultrasound waves create microbubbles in a fluid – a phenomenon called cavitation. In a current study, this process is used to destroy liver tumors and metastases.
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Image: Four men next to a CT - Peter Brotchie, Dr. Ruwan Tennakoon, Prof. John Thangarajah, Dr. Mark Page; Copyright: St Vincent's Hospital Melbourne

St Vincent's Hospital Melbourne

New AI tech for early detection of prostate cancer

16.07.2021

Prostate cancer is the most diagnosed cancer and a leading cause of death by cancer in Australian men. Early detection is key to successful treatment, but men often dodge the doctor, avoiding diagnosis tests until it is too late.
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Image: Artist’s rendering of small star-shaped machines between red blood cells; Copyright: PantherMedia/Michael Osterrieder

Autonomous medical devices: running well in your body

01.02.2021

In theory, autonomous medical technologies can be used in a diagnostic or therapeutic capacity inside the body under certain conditions. This may not sound like a new invention at first. After all, implantable cardioverter-defibrillators have monitored and fixed abnormal heart rhythm for many years.
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Image: Two small, angular-shaped, electrical devices that are held with tweezers; Copyright: Fraunhofer EMFT/Bernd Müller

Tumor therapy: drug delivery pump instead of injection

01.02.2021

Drugs always have undesired side effects. Cytostatics are powerful drugs used to treat cancer. They reach almost all cells in the body, killing healthy cells as well as cancer cells in the process. A targeted delivery to the specific cellular site would be a gentler treatment.
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Image: Laboratory situation - Prof. Popp shows a young man a small object in his hand; Copyright: Leibniz-IPHT/Sven Döring

Leibniz-IPHT/Sven Döring

Tumor excision: triple imaging for unique diagnostics

08.08.2019

After their tumor has been removed, some patients have to return to the hospital to undergo surgery again. That's because the tumor was not precisely identified and was subsequently not completely removed. That's both an ethical and financial dilemma. A new surgery-adjacent procedure is designed to rapidly and accurately detect tumors.
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Functional Imaging: The puls of modern oncology

17.06.2019

Medical imaging techniques have developed considerably in recent decades. In addition to morphological imaging techniques more and more functional imaging techniques are used in oncology that can continously record the functions of specific organs locally and regionally in real time. These are groundbreaking for diagnostics, therapies and preoperative preparations.
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Photo: Preview picture of video

Where imaging and radiation meet – Radiotherapy with the MR-Linac

13.02.2019

In conventional radiotherapy, the tumor is first localized using CT and MRT images in order to calculate the irradiated areas. The major drawback in this case: the subsequent radiation only shows bone structures in the body but not the tumor itself. As a result, the radiated area is often larger than necessary. In our video you will learn how the MR-Linac can be used for more precise radiotherapy.
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