Smart pills with AI for gastrointestinal health monitoring
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Image: Fluorescence microscopy image of a lab-grown

Thomas Dennison/University of Cambridge

Lab-grown 'mini-guts' offer new insights for Crohn’s disease treatments

06.09.2024

Researchers at the University of Cambridge have developed lab-grown "mini-guts" to better understand and treat Crohn’s disease, a chronic inflammatory bowel disease affecting millions worldwide. These mini-guts, or organoids, mimic the gut lining's key functions and could pave the way for more personalized and effective treatments.
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Image: Doctor shows patient the human digestive system on a tablet and explains the details.

Gastrointestinal diagnostics: The Sonopill and AutoCapsule projects

29.08.2024

Capsule endoscopy has revolutionized gastrointestinal tract diagnosis over the past decade. The Sonopill program, led by Professors Marc Desmulliez and Sandy Cochran, is at the forefront of integrating ultrasound imaging and therapy into capsule technology.
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Image: A researcher places cells in a centrifuge.

Identifying a high-risk biomarker for gastric cancer recurrence risk

16.08.2024

A recent study led by researchers at the Medical University of Vienna has identified the AF1Q gene as a significant biomarker for predicting the risk of gastric cancer relapse. This discovery could enhance personalized treatment strategies and improve survival rates for patients. The study was published in Scientific Reports.
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Image: Person demonstrating the use of a gastrointestinal model to test AI-driven ingestible sensors in a lab setting; Copyright: Khan Lab at USC Viterbi School of Engineering

Khan Lab at USC Viterbi School of Engineering

Smart pills with AI: Advancing gastrointestinal health monitoring

09.08.2024

Researchers at the USC Viterbi School of Engineering have developed advanced ingestible sensors that utilize AI and wearable electronics to provide real-time 3D monitoring of gastrointestinal health. These innovative smart pills can detect stomach gases and track their location within the body, offering potential for early disease detection.
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Image: A researcher cultivates bacteria on an agar plate in a laboratory

Plasmids in the human intestine: new findings on their use as biomarkers

27.05.2024

The Carl von Ossietzky University of Oldenburg has published a study in which an international research team reports on the discovery of a potential biomarker from the human intestine. This plasmid could be used in the future to detect fecal contamination or monitor inflammatory bowel diseases. The results were published in the journal Cell.
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Image: A close-up picture of a capsule; Copyright: Gerard Cummins, University of Birmingham

Gerard Cummins, University of Birmingham

Swallowable sensors advance gastrointestinal health monitoring

03.05.2024

Researchers from Heriot-Watt University and the University of Birmingham, along with colleagues from the University of Edinburgh, have introduced an ingestible capsule equipped with sensors to monitor gut movement, potentially improving gastrointestinal diagnostics and treatment.
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Image: This image shows two screens. The one of the right shows the word AI and the left some text. On the right side, there is a man looking at the screens.

Prototype applies AI to advance colorectal diagnosis

15.03.2024

Portuguese researchers from the Institute for Systems and Computer Engineering, Technology and Science (INESC TEC) and the IMP Diagnostics Molecular & Anatomic Pathology laboratory have unveiled the world's first prototype applying Artificial Intelligence (AI) to colorectal diagnosis.
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The photo shows a hand holding a silver, tubular device which improves imaging and detecting gastrointestinal cancer; Copyright: J. Crowley

J. Crowley

Imaging device for early gastrointestinal cancer detection

01.03.2024

Gastrointestinal cancers (GCs) pose a significant health challenge worldwide, with early detection being crucial for effective treatment and improved survival rates. To address this need, scientists have developed a new imaging device aimed at enhancing the accuracy and accessibility of GC screening programs.
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Image: Image of fluorescently labeled nanoparticles (pink) in human colon cancer cells (green) 24 hours after addition to cell culture; Copyright: umg/Dr. Dolma Choezom

umg/Dr. Dolma Choezom

Project CANACO: better imaging-based and targeted therapy of colon cancer

01.11.2023

The University Medical Center Göttingen (UMG) is coordinating the development of a new nanoparticle-based method for the personalized therapy of patients suffering from colon cancer.
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Image: Judit Burgaya and Prof. Dr. Marco Galardini in the TWINCORE at a bar table with a laptop; Copyright: Karin Kaiser / MHH

Karin Kaiser / MHH

How harmless turns dangerous

24.08.2023

MHH researcher Prof. Galardini from the RESIST Cluster of Excellence finds causes for bloodstream infections in the genes of bacteria. This will enable better diagnostics and vaccinations in the future.
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Image: Man in a dark blue jacket and shirt, Prof. Jakob N. Kather, stands in a corridor and smiles at the camera; Copyright: EKFZ

EKFZ

AI against bowel cancer: research project DECADE

12.07.2023

The DECADE research project is the first to use swarm learning in cancer research. The German Cancer Aid is funding the joint project of several university hospitals with around 1.5 million euros.
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Image: Close-up of an ultrasound scan of a female abdomen by a female doctor; Copyright: Natabuena

Natabuena

Functional imaging: intestinal and liver diseases mutually influence each other

06.07.2023

The research groups of Prof. Trautwein (University Hospital RWTH Aachen) and Prof. Hengstler (Leibniz Research Centre for Working Environment and Human Factors in Dortmund) have made a surprising discovery about the interaction of the liver and the intestine.
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Image: The hydrogel composite is demonstratively stretched by Alexandre Anthis; Copyright: Empa

Empa

Sensor patch for abdominal surgery

23.06.2023

Researchers from Empa and ETH Zurich have developed a plaster with a sensor function to ensure that wounds in the abdomen remain tightly closed after an operation.
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Image: A computer that evaluates stool samples using bioinformatic methods; Copyright: Anna Schroll/Leibniz-HKI

Anna Schroll/Leibniz-HKI

Model shows intestinal bacteria influence growth of fungi

22.05.2023

The bacteria present in the intestine provide information about the quantities of fungi of the potentially disease-causing Candida genus.
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Image: 3D illustration of a human body showing the gastrointestinal tract highlighted; Copyright: SciePro/Shutterstock

SciePro/Shutterstock

Morbus Crohn: new imaging technique for effective therapy

12.04.2023

An interdisciplinary research group at MedUni Vienna has investigated a new imaging technique that can improve the treatment of intestinal strictures from Morbus Crohn.
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Image: Logo of the EU project miGut-Health, black, violet and green colors on a white background; Copyright: Eurice Office

Eurice Office

Personalised health blueprint to prevent and predict inflammatory bowel disease

07.03.2023

Project led by PMI member Prof. Andre Franke aims to empower people affected by Crohn’s disease and ulcerative colitis by developing interdisciplinary solutions for improved disease prevention and health promotion.
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Image: Two men and a woman stand in front of a building and smile for the camera; Copyright: RUB, Marquard

RUB, Marquard

AI with infrared imaging enables precise colon cancer diagnostics

23.02.2023

Researchers at the Centre for Protein Diagnostics PRODI at Ruhr University Bochum, Germany, are using artificial intelligence in combination with infrared imaging to optimally tailor colon cancer therapy to individual patients.
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Image: A sleeveless shirt is shown with a transmitter that sends the data to a smartphone via radio link; Copyright: Osaka Metropolitan University

Osaka Metropolitan University

Realtime monitoring with wearable reveals IBS-related changes

18.01.2023

Associate Professor Fumio Tanaka and his research group at the Osaka Metropolitan University Graduate School of Medicine recorded the autonomic nervous system activity of IBS patients and healthy subjects using a wearable device and tracked activities such as defecation and sleep.
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Image: Two doctors in scrubs look at a screen during an AI-assisted colonoscopy; Copyright: Universitätsklinikum Bonn (UKB)

Universitätsklinikum Bonn (UKB)

AI improves colorectal cancer screening in Lynch syndrome

10.01.2023

Researchers at the National Center for Hereditary Tumor Diseases (NZET) at Bonn University Hospital (UKB) have now found that artificial intelligence (AI) can improve the effectiveness of colonoscopy in the presence of Lynch syndrome.
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Image: Person in the laboratory holding cell samples under a microscope; Copyright: MICROGEN@GMAIL.COM

MICROGEN@GMAIL.COM

Molecular markers: predicting the most effective treatment for IBD

09.08.2022

Early effective treatment can help manage this condition and improve the quality of life of patients. A research project aims to identify molecular markers to better assess the chances of success of certain biological therapies and subsequently determine the best individualized treatment plan.
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Image: Man and woman in a laboratory presenting a multi-organ chip; Copyright: TissUse GmbH

Multi-Organ Chips – The Patients of Tomorrow?

01.02.2019

The liver, nervous tissue or the intestines: all are important human organs that have in the past been tested for their function and compatibility using animal or in vitro test methods. In recent years, TissUse GmbH, a spin-off of the Technical University of Berlin (TU Berlin), has launched multi-organ chip platforms. But that’s not all.
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