COVID-19 and beyond - Understanding infectious diseases
COVID-19 and beyond - Understanding infectious diseases
COVID-19 has brought laboratory medicine into focus in many areas. Chemical, microbiological and immunological procedures enable precise diagnostics in the laboratory. Physicians can now identify diseases even more precisely and suggest therapies based on laboratory findings. Experience the innovative technologies and explore the laboratory of the future.
Discover the most innovative laboratory medical techniques!
Looking for new laboratory techniques? Products and exhibitors for laboratory technology and diagnostics can be found in the MEDICA 2020 catalogue!
A University of Cincinnati immunologist is recommending that individuals with contact dermatitis choose facial masks made without elastic or rubber that allow them to stay safe in the midst of COVID-19 while avoiding possible allergic reactions.
A new study, led by researchers from the University of California, Irvine, has deepened the understanding of epigenetic mechanisms in tumorigenesis and revealed a previously undetected repertoire of cancer driver genes. The study was published this week in Science Advances.
UC San Francisco scientists have developed a single clinical laboratory test capable of zeroing in on the microbial miscreant afflicting patients hospitalized with serious infections in as little as six hours -- irrespective of what body fluid is sampled, the type or species of infectious agent, or whether physicians start out with any clue as to what the culprit may be.
In the quest to image exceedingly small structures and phenomenon with higher precision, scientists have been pushing the limits of optical microscope resolution, but these advances often come with increased complication and cost.
A new University of Saskatchewan (USask) study has found that exercise performance and blood and muscle oxygen levels are not affected for healthy individuals wearing a face mask during strenuous workouts.
Pacemakers and other implantable cardiac devices used to monitor and treat arrhythmias and other heart problems have generally had one of two drawbacks - they are made with rigid materials that can't move to accommodate a beating heart, or they are made from soft materials that can collect only a limited amount of information.
Researchers at the RIKEN Center for Biosystems Dynamics Research have developed human-skin equivalent that reproduces traction-force balance in the lateral direction, a property that controls the structure and physiological function of skin. This artificial skin will enhance in-depth analyses of physiological skin functions.
Researchers at the University of Basel have developed a precisely controllable system for mimicking biochemical reaction cascades in cells. This "cell on a chip" is useful not only for studying processes in cells, but also for the development of new synthetic pathways for chemical applications or for biological active substances in medicine.
Scientists have created synthetic soft surfaces with tongue-like textures for the first time using 3D printing, opening new possibilities for testing oral processing properties of food, nutritional technologies, pharmaceutics and dry mouth therapies.
A test to diagnose two very serious diseases such as ALS and FTD when the pathologies have not yet appeared, thereby providing doctors and patients with essential information tools to tackle them early and develop new treatments. A team of researchers at SISSA in association with different clinical and Italian research institutes have made a first promising step in this direction.
Stress is present everywhere, even bacteria and plant cells have to cope with it. They express various specific stress proteins, but how exactly this line of defense works is often not clear. A group of scientists headed by Professor Dirk Schneider of Johannes Gutenberg University Mainz (JGU) has now discovered a protective mechanism in cyanobacteria as well as in chloroplasts of plant cells.
Researchers of the Technical University of Munich (TUM) have cultured so-called intestinal organoids from human intestinal tissue, which is a common byproduct when performing bowel surgery. These small “miniature intestines” can be used for molecular biological examinations and allow for a direct application of research results to humans, thereby making animal experiments redundant.
A new study jointly led by Professor Tom Wilkinson and Dr Tristan Clark of the University of Southampton, has shown a blood test for five cytokines could help predict those at risk of life-threating overstimulation of immune defenses by COVID-19, and potentially tailor their treatment to tackle this.
The Technical University of Munich (TUM) is starting five new research projects that focus on the coronavirus and the search for new active ingredients. For example, the use of algorithms could ensure a more precise classification of the illness in the future.
In Judith Su's Little Sensor Lab, researchers are working to sense tiny amounts - down to a single molecule - of everything from doping agents to biomarkers for cancer, Alzheimer's disease, Lyme disease and, yes, even COVID-19.
Researchers with the U.S. Army Futures Command are part of a team that tested alternative ways to measure COVID-19 antibody levels, resulting in a process that is faster, easier and less expensive to use on a large scale. Their method holds promise for accurately identifying potential donors who have the best chance of helping infected patients through convalescent plasma therapy.
Rapid detection of the SARS-CoV-2 virus, in about 30 seconds following the test, has had successful preliminary results in Mano Misra's lab at the University of Nevada, Reno. The test uses a nanotube-based electrochemical biosensor, a similar technology that Misra has used in the past for detecting tuberculosis and colorectal cancer as well as detection of biomarkers for food safety.
Around 15 percent of Parkinson's disease cases are related to a known genetic background, out of which mutations in the Parkin and PINK1 genes are among the most frequent ones. Thus, revealing cellular mechanisms which are altered by these mutations is crucial for the development of new therapeutic approaches.
Extracellular vesicles (EVs) - nanometer sized messengers that travel between cells to deliver cues and cargo - are promising tools for the next generation of therapies for everything from autoimmune and neurodegenerative diseases to cancer and tissue injury.
Genetic mutations that promote the growth of the most common type of adult brain tumors can be accurately detected and monitored in blood samples using an enhanced form of liquid biopsy developed by researchers at Massachusetts General Hospital (MGH).
The closer people are physically to one another, the higher the chance for exchange, of things like ideas, information, and even infection. Now researchers at MIT and Boston Children's Hospital have found that, even in the microscopic environment within a single cell, physical crowding increases the chance for interactions, in a way that can significantly alter a cell's health and development.
Smartlab – Robotics and automation in the laboratory
Some tasks in the laboratory are repetitive, need to be done extremely precise and require a lot of time. Such tasks are very tedious for humans, but they are tailor-made for robots. Such is the case with the "AutoCRAT" project at the Fraunhofer Institute for Production Technology IPT in Aachen. Here, a robotic platform is developed to produce stem cells for the treatment of osteoarthritis. Hear how this works and what it looks like from Ferdinand Biermann and Jelena Ochs in our video interview.
Disinfection methods of hospital drinking water - Fully automatic legionella prevention
Besides hand hygiene, drinking water hygiene is also on the to-do list of every hospital. A lot of money is invested to clean water pipes and to destroy legionella germs. An alternative solution for mechanical and thermal control is water disinfection using an automatic machine. Dr. Bernhard Heising, infection specialist and hospital hygienist at Düren Hospital, Germany, describes in an interview why the hospital uses this solution and what advantages it offers.