24/02/2021Researchers who focus on fat know that some adipose tissue is more prone to inflammation-related comorbidities than others, but the reasons why are not well understood. Thanks to a new analytical technique, scientists are getting a clearer view of the microenvironments found within adipose tissue associated with obesity.
22/02/2021Working with colleagues from Germany and the US, researchers at Leipzig University have achieved a breakthrough in research into how cancer cells spread. In experiments, the team of biophysicists led by Professor Josef Alfons Käs, Steffen Grosser and Jürgen Lippoldt demonstrated for the first time how cells deform in order to move in dense tumor tissues and squeeze past neighboring cells.
19/02/2021Mass spectrometry (MS) is a powerful method for biomarker analysis because it enables highly sensitive and accurate measurement of target molecules in clinical samples. The application of MS to clinical diagnosis, such as neonatal metabolic screening, has been progressing with a focus on metabolite markers.
19/02/2021With the help of artificial intelligence (AI) a German-American team of scientists deciphered some of the more elusive instructions encoded in DNA. Their neural network trained on high-resolution maps of protein-DNA interactions uncovers subtle DNA sequence patterns throughout the genome, thus providing a deeper understanding of how these sequences are organized to regulate genes.
18/02/2021Is the tissue healthy or pathologically altered? Is the antibiotic effective against a certain bacterium or is the bacterium resistant to it? Raman spectroscopy can help to answer such questions quickly and precisely. However, one challenge for the use of the light-based analysis method in everyday clinical practice is that the results can be highly sensitive to the measurement conditions.
15/02/2021For the first time, engineered heart muscle (EHM) from human induced pluripotent stem cells (iPSCs) will be used to treat patients with heart failure. After regulatory approval, recruitment of the first patient for the first-in-class, first-in-patient BioVAT-HF early clinical trial has started in Göttingen, Germany.
15/02/2021To study early stages in embryonic development in the cell culture dish, scientists use so-called human pluripotent stem cells (hPSC). These are cells with have remarkable special properties that can be multiplied as they can indefinitely multiply and are capable of forming any functional cell type of the body.
12/02/2021A specialized laboratory of the ARTORG Center for Biomedical Engineering Research, University of Bern, headed by Olivier Guenat has developed a new generation of in-vitro models called organs-on-chip for over 10 years, focusing on modeling the lung and its diseases.
11/02/2021A team of engineers and scientists has developed a method of 'multiplying' organoids: miniature collections of cells that mimic the behavior of various organs and are promising tools for the study of human biology and disease.
11/02/2021Colorectal cancer screening rates jumped by more than 1,000 percent when researchers sent take-at-home tests to patients overdue for testing at a community health center that predominantly serves people of color.
10/02/2021A Cleveland Clinic-led team of researchers has developed a personalized genomic medicine platform that will help advance accelerate genomic medicine research and genome-informed drug discovery, according to new study results published in Genome Biology.
03/02/2021Doctors are increasingly using genetic signatures to diagnose diseases and determine the best course of care, but using DNA sequencing and other techniques to detect genomic rearrangements remains costly or limited in capabilities.
29/01/2021The treatment of cancer with new, individualized cell therapies is usually very costly and lengthy. Before treatment can take place, patients often have to wait a long time for individualized therapeutics to be produced and they lose valuable time.
29/01/2021A team from the Gamma and Neutron Spectroscopy Group of the Corpuscular Physics Institute (IFIC) has patented a new device for real-time guided biopsies, with direct application in any type of cancer that requires a biopsy and whose process must be carried out using ultrasound.
27/01/2021The Institute for Research in Biomedicine (IRB; Bellinzona, Switzerland), affiliated to the Università della Svizzera italiana (USI) developed a second-generation 'double antibody' that protects from SARS-CoV-2, the virus causing COVID-19, and all its tested variants. It also prevents the virus from mutating to resist the therapy.
27/01/2021Drug research and artificial skin replacement - these are the areas in which tissue engineering and bioprinting are already used today. What else could be possible in the future? We asked Dr. Nadine Nottrodt from Fraunhofer ILT and Prof. Sabine Neuß-Stein from RWTH Aachen University Hospital!
25/01/2021Viral respiratory diseases are easily transmissible and can spread rapidly across the globe, causing significant damage. The ongoing covid-19 pandemic is a testament to this. In the past too, other viruses have caused massive respiratory disease outbreaks: for example, a subtype of the influenza virus, the type A H1N1 virus, was responsible for the Spanish flu and the Swine flu outbreaks.
22/01/2021The neocortex is the part of the brain that humans use to process sensory impressions, store memories, give instructions to the muscles, and plan for the future. These computational processes are possible because each nerve cell is a highly complex miniature computer that communicates with around 10,000 other neurons. This communication happens via special connections called synapses.
22/01/2021Successful precision cancer diagnosis through an AI analysis of multiple factors of prostate cancer. Potential application of the precise diagnoses of other cancers by utilizing a urine test.
21/01/2021Chronic inflammatory bowel disease (CIBD) in particular is suspected to be closely linked to the composition and (im-)balance of the intestinal microbiome. However, the causal relationship between the microbiome and the development of disease and determining factors of the composition of the microbiome in the individual are still largely unexplained.
21/01/2021Researchers at Lund University in Sweden, in collaboration with colleagues in Dresden, Germany, have developed a way of combining a bone substitute and drugs to regenerate bone and heal severe fractures in the thigh or shin bone.
20/01/2021Just a few millimetres thick, articular cartilage plays a crucial role in our musculoskeletal system, since it is responsible for smooth (in the truest sense of the word) movement. However, the downside of its particular structure is that even minor injuries do not regenerate. Timely treatment of cartilage damage is therefore essential.
19/01/2021Imagine going to a surgeon to have a diseased or injured organ switched out for a fully functional, laboratory-grown replacement. This remains science fiction and not reality because researchers today struggle to organize cells into the complex 3D arrangements that our bodies can master on their own.
19/01/2021Organoids are increasingly being used in biomedical research. These are organ-like structures created in the laboratory that are only a few millimetres in size. Organoids can be used to study life processes and the effect of drugs. Because they closely resemble real organs, they offer several advantages over other cell cultures.
18/01/2021One of the most vexing aspects of the COVID-19 pandemic is doctors' inability to predict which newly hospitalized patients will go on to develop severe disease, including complications that require the insertion of a breathing tube, kidney dialysis or other intensive care.
15/01/2021Researchers at Carnegie Mellon University report findings on an advanced nanomaterial-based biosensing platform that detects, within seconds, antibodies specific to SARS-CoV-2, the virus responsible for the COVID-19 pandemic. In addition to testing, the platform will help to quantify patient immunological response to the new vaccines with precision.
11/01/2021Prof. Volker Busskamp from the University of Bonn has received a "Proof of Concept Grant" worth 150,000 euros from the European Research Council (ERC). He and his team are working at the Eye Clinic of the University Hospital Bonn on a technology to rapidly program human stem cells to photoreceptor for retinal research and treating blindness in the future.
10/12/2020When wounded, our body sets off a complex immune response. As part of it, the wound produces small antimicrobial molecules to fight off the pathogens locally. They signal across tissues from the site of injury to the brain, sending a message to increase sleep and raise the chances for surviving the injury. The results have been published in the journal "Current Biology".
08/12/2020Our bodies constantly make sounds that are not always audible to the naked ear. The occurrence of certain noises or changes in normal sounds can be an indication of illness. Using the example of the lung, a research team at Graz University of Technology has been intensively engaged in noise recording and the development of computer-aided analysis methods as a supplement to medical diagnosis.
08/12/2020As the COVID-19 pandemic continues to spread across the world, testing remains a key strategy for tracking and containing the virus. Bioengineering graduate student, Maha Alafeef, has co-developed a rapid, ultrasensitive test using a paper-based electrochemical sensor that can detect the presence of the virus in less than five minutes.
02/12/2020To develop effective therapeutics against pathogens, scientists need to first uncover how they attack host cells. An efficient way to conduct these investigations on an extensive scale is through high-speed screening tests called assays.
16/11/2020New for MEDICA 2020 AMD is excited to introducing our four new Respiratory Panels. Viruses that affect the human respiratory system manifest themselves in a number of ways, with most people...
16/11/2020DiaSys is pleased to offer HDL-c direct FS, a new homogenous assay for direct determination of HDL-cholesterol (HDL-C). HDL-C monitoring is of great importance for cardiovascular risk assessment since...
16/11/2020CAMPTON Reader 100 enables the detection of biomarkers e.g. for infections, cancer, autoimmune or other diseases from a whole blood sample within a few minutes Serological and molecular biological...
13/11/20202020 has been a strange year all round. An unknown virus, probably originating in a bat colony in central China, mutated to allow it to also infect humans. Within three months of the virus being...
13/11/2020Blood thickness is emerging as an important indicator of dangerous complications in Covid-19 patients, causing demand for the blood viscometers manufactured by Benson Viscometers in West Wales to...
13/11/2020One of the biggest challenges facing medical teams treating Covid-19 patients is identifying which ones are likely to suffer the most extreme responses to the virus. Knowing this would make it...
13/11/2020Covid-19, or SARS-COV-2, which emerged in late 2019, continues to spread around the world, infecting more than 4.5m people at time of writing, and leading to more than 300,000 deaths. The...
13/11/2020Test for the detection of coronavirus SARS-CoV-1/2 (COVID-19) A new severe respiratory syndrome caused by a coronavirus was first observed in Wuhan (China) in December 2019. The infection has...
12/11/2020Get a proof of infection with the SARS-CoV-2 virus or of immunity to the virus within one hour. Accelerate healing processes with electrical stimulation through an active wound patch. Fraunhofer ENAS...
12/11/2020San Diego, CA, November 2, 2020 — ACON Laboratories, Inc., a leading global medical device manufacturer announced today the launch of its Flowflex™ SARS-COV-2 Antigen Rapid Test. The...
11/11/2020PixoTest® is among the fastest COVID-19 antigen tests for smarter pandemic management, detecting positive SARS-CoV-2 infection in as short as five minutes. The PixoTest® POCT Analyzer offers...
06/11/2020Shanghai Chemtron's new coronavirus (2019-nCoV) IgM/IgG antibody rapid test kit (colloidal gold ) and new coronavirus (2019-nCoV) IgM antibody rapid test kit (colloidal gold ) are...
05/11/2020STAT-NAT®COVID-19 MULTI is the new configuration of ready-to-use lyo Real-Time PCR mix for the detection of novel coronavirus disease. The world is experiencing a fast increase of SARS-CoV-2 testing...
04/11/2020Dielectric filter solutions for PCR analyzers Enabling SARS-CoV-2 detection with high-performance fluorescence filters by Optics Balzers Standard off-the-shelf optical filters often struggle to...
04/11/2020Adaptable filters for fluorescence analysis One filter to rule them all – a versatile solution fitting numerous fluorophores High-End fluorescence microscopes as well as fluorescence spectrometers...
26/10/2020During this Coronavirus crisis, all the attention of clinicians around the world lays on the direct diagnosis of the COVID-19 disease, whether by PCR, Rapid Tests or classical serology. However, cell...
25/10/2020The Covid-19 pandemic is affecting the whole world and Norma is dedicated to contribute and help to this still growing and sadly, worsening virus outbreak that is threatening many of our lives...
23/10/2020Genrui Biotech Inc. released SARS-CoV-2 Antigen Test Kit (Colloidal Gold)-affordable, high-quality Covid-19 antigen rapid tests. The antigen test kits are highly portable, reliable, easy to...
10/10/2020Original article published on 10/10/2020 Iceni Diagnostics has appointed BBI Solutions to generate clinical trial batches for their new, rapid SARS-COV-2/Influenza virus detection test. The test...
08/10/2020Unlike the products marketed to date, the test developed by SYnabs, Coris BioConcept, Unisensor, and Bio- X Diagnostics, is the only rapid solution (developed in different formats) that can detect an...
08/10/2020ASKION - Mid-sized technology company from Gera that went around the world Since 15 years ASKION is a reliable provider of customer specific devices and assemblies. Our know how and experience...
22/09/2020MEDICAL FAIR ASIA 2020 goes Digital with Online Convenience for Medical Sourcing Needs Ten-day digital experience for a vibrant marketspace to conduct business 24/7 Singapore, 22 September 2020 –...
20/08/2020BBI Solutions is recruiting for roles to support its work as part of a UK Government consortium, tasked with developing and manufacturing a Covid-19 Point of Care antibody test to support the...
06/08/2020BBI Solutions is pleased to announce it has been appointed to manufacture the saliva-based rapid SARS-COV-2 antigen test that is being developed by Affimer® biotherapeutics and reagents developer...
12/12/2019Diagnostic testing usually takes some time and a sterile environment to get the results. To cut down on the costs and effort spend on these tasks there are different diagnostic tests. One of them are single-use tests offered by SensDx S.A. The technology behind them not only makes the process faster and easier, but provides the opportunity to expand into home use in the future as well.
08/11/2019If physicians suspect an acute myocardial infarction, they first order an ECG. This test is very established and allows cardiologists to quickly diagnose acute heart attacks – though the test does not detect less common heart attack symptoms. So far, those patients had to wait up to twelve hours before a heart attack could be accurately diagnosed or ruled out. But things are about the change.
04/11/2019Soon, the world's largest trade fair for medical technology will open its doors again: More than 5.000 exhibitors will present their newest products and ideas at MEDICA from 18 to 21 November. You will not only meet well-known companies here, but also lots of young start-ups. Or, you can visit the MEDICA forums and conferences to experience a rich program of lectures and discussions.
04/11/2019Laboratories are medicine’s secret weapon because they handle the lion’s share of diagnostics often without patients even realizing it. That’s why the continuing workforce shortage in both laboratory medicine and companies is especially troubling. The MEDICA LABMED FORUM 2019 plans to address and counteract this development.
08/10/2019The healthcare market offers a multitude of microscopes that make cells visible to the human eye. The same applies to AI-based software for image analysis. After taking the microscopic images, scientist are faced with large volumes of scans with usually low resolution. Yet when all aspects merge together, they open up a the world of digital pathology.
23/09/2019For patients waiting for donor organs, every day can mean the difference between life and death. Making things even more complicated is the fact that not every organ is a compatible match with the patient. It would mean enormous progress if we could grow organs from the patient's own cells in the lab. That's why patients with heart disease place big hope in tissue engineering.
08/08/2019After their tumor has been removed, some patients have to return to the hospital to undergo surgery again. That's because the tumor was not precisely identified and was subsequently not completely removed. That's both an ethical and financial dilemma. A new surgery-adjacent procedure is designed to rapidly and accurately detect tumors.
01/08/2019Antibiotic resistance is on the rise in all parts of the world, complicating medical treatment of serious bacterial infections in patients. The World Health Organization estimates that approximately 33,000 people die each year from antibiotic-resistant bacteria in Europe alone. Bacteria that are resistant to multiple or even all known antibiotics pose an ever-increasing threat.
01/08/2019Antibiotic resistance is modern medicine's greatest challenge. Some bacteria only respond to a handful of antibiotics, prompting hospitals to spend a lot of time finding an effective drug. That’s why it is critical for physicians to rapidly identify antibiotic resistance to avoid ineffective treatments.
01/08/2019An untreatable infection is a nightmare for physicians and potentially life-threatening to the patient. Unfortunately, more and more pathogens emerge that are resistant to drugs, especially antibiotics. We need to use our drugs smartly and come up with technical solutions as well to prevent our weapons from blunting in the future.
01/08/2019The medical devices value chain has gaps between academic research and industrial practice that slow down innovation processes. This also applies to time-sensitive and urgently needed products such as rapid diagnostic tests to identify resistant pathogens. At the InfectoGnostics Research Campus in Jena, partners from research and medicine team up to close these gaps.
08/07/2019On November 18th, 2019, parallel to the first day of MEDICA, the world forum for medicine, the Diagnostics Partnering Conference (DxPx Conference) will take place in Düsseldorf, bringing together stakeholders in the diagnostics and research tool industry. The DxPx Conference focuses on discovering technologies, finding financing and investment opportunities and forming collaborative partnerships.
22/03/2019Over six million people in Germany have diabetes. It is estimated that almost 400 million people are affected by this disease worldwide. Diabetes sufferers must prick their fingers several times a day to monitor their blood sugar.
01/03/2019Coughing, airway obstruction, difficulty breathing: Chronic obstructive pulmonary disease (COPD) is an umbrella term used to describe progressive and currently incurable lung diseases. The innovative solutions of Philips Respironics help patients to manage each stage of the disease and their medication intake, train the respiratory system and provide respiratory support.
01/02/2019In vitro processes and animal tests are used to develop new medications and novel therapeutic approaches. However, animal testing raises important ethical concerns. Organ-on-a-chip models promise to be a feasible alternative. In a system the size of a smartphone, organs are connected using artificial circulation.
01/02/2019The liver, nervous tissue or the intestines: all are important human organs that have in the past been tested for their function and compatibility using animal or in vitro test methods. In recent years, TissUse GmbH, a spin-off of the Technical University of Berlin (TU Berlin), has launched multi-organ chip platforms. But that’s not all.
01/02/2019Organ-on-a-chip systems are technically a great enhancement of medical research because they facilitate testing of active ingredients on cell cultures in the chambers of a plastic chip. This replaces animal testing and improves patient safety. That being said, they are not a true-to-life replication of the human body and can only simulate a few functions and activities.
01/02/2019So far in vitro methods and animal experiments have been used to determine the causes of diseases, research therapeutic approaches and predict the effect of drugs. Organ-on-a-chip models now offer a more accurate and ethically justifiable alternative. Find out more about the models, their advantages and future developments in our Topic of the Month.
02/01/2019While they are very useful, health apps have one major drawback: anyone can release and distribute them unchecked. Only some apps require medical device certification. So how can users spot a great, safe and useful app? When it comes to diabetes apps, the “DiaDigital” seal of distinction is the answer.
02/01/2019Monitoring blood sugar levels, counting carbohydrates, calculating insulin doses, and keeping accurate records - diabetes is a data-intensive disease that demands a lot of self-discipline and attention from the patients. Some concerns are patients neglecting to keep a food journal, "fudged" test results or calculation errors. Digital solutions help patients easily manage the large volumes of data.
02/01/2019Diabetes mellitus or simply diabetes has become very common and is often described as a lifestyle disease. More and more people are suffering from this chronic metabolic disorder. Next to established diagnostic procedures, digital retinal screening has shown to be successful - a promising technique that will also play an important role in the diagnosis of other diseases in the future.
02/01/2019There are 425 million people with diabetes in the world. Heart problems, kidney failure or blindness - these can all be consequences of the metabolic disease. Diabetes patients now have the possibility of being treated digitally.
21/11/2018Our blood reveals a lot about our physical health. The shape of our blood cells sheds light on several hereditary diseases for example. For a diagnosis, the cells must first be examined under the microscope and categorized into a specific cell class. We met with Dr. Stephan Quint and Alexander Kihm of the Institute of Physics at the Saarland University, who explained how this classification works.
12/11/2018Even before MEDICA begins, the Düsseldorf trade fair grounds are alive like a beehive: in the halls, stands are built and exhibits are delivered, while the trade fair management coordinates logistics and services for exhibitors and visitors. We were still able to have a short talk to Horst Giesen, Global Portfolio Director Health & Medical Technologies of Messe Düsseldorf, despite all the bustle.
02/11/2018This is what diagnostic investigation normally looks like: a patient sample is collected, sent to the laboratory and analyzed. Once that's completed, the patient is told of the lab test result. But if the patient is a high-performance athlete and has to follow and stick to a rigid training schedule, he or she needs these results immediately. What makes this possible? Point-of-care testing!
02/11/2018It's time: the world's largest medical trade fair opens its doors from 12 to 15 November. More than 5,000 international exhibitors will present their new innovative products and applications. Frums, conferences and special shows will feature exciting specialist lectures and discussions that will give you an insight into electromedicine, laboratory medicine, medical technology and diagnostics.
22/08/2018Mix-ups, contamination and sample loss – most errors in pathology happen when specimen are received. Countless samples arrive daily at the laboratory, while the sample entry process is very monotonous. As a result, the work is inefficient. The start-up company inveox has now developed a system that automates the processes in the pathology laboratory, thus making them more efficient.
09/07/2018People who are not ill and do not show any symptoms typically do not visit the doctor. And while most people know that preventive medical checkups for cancer, for example, are important, they still avoid them. They tend to be very hesitant because the doctor might detect a serious illness. In the future, a new type of implant could make it easier to go to a screening test.
22/06/2018A drop of blood provides a lot of valuable information. However, it takes several hours to analyze the blood of a patient and make a diagnosis. This takes away a lot of time that's crucial for treatment. A new method intends to considerably speed up this process by testing the cells in the blood in terms of their deformability and immune response.
30/04/2018Medicine is getting more and more personalized. This is particularly interesting for oncology, since a cancer is as individual as the respective patient. When choosing a therapy, both the characteristics of the tumor and the personal characteristics of the patient must be considered. To see exactly what this looks like, we visited the diagnostics company TherapySelect, based in Heidelberg.
23/04/2018A bypass is a complicated structure. It is either made of synthetic materials that can cause blood clots and infections or created by using the patient’s veins. However, the latter often does not yield adequate material. A newly developed bioreactor could solve this problem in the future. It is designed to tissue engineer vascular grafts by using the body’s own material.
01/03/2018Conventional cancer treatment selection typically depends on the location of the tumor. However, this approach ignores the distinct gene mutations in the tumor of the individual patient. New cancer research approaches increasingly emphasize the concept of personalized therapy.
01/03/2018Personalized medicine does not want to measure all patients with the same yardstick anymore. Instead, it aims to precisely fit the therapy to the cause of their disease. This often means a more successful treatment with less side effects for patients. And for physicians, interdisciplinary cooperation and decision making come to the fore.
01/03/2018Personalized medicine does not follow a "one-size-fits-all" treatment approach but emphasizes a "tailor-made" paradigm, meaning a treatment is customized to each individual person's case. For patients, this increases the chances of treatment success and means fewer side effects. While the approach originates in the field of oncology, it is now also increasingly applied to other disease patterns.
01/03/2018Everyone is different. This statement also applies to our health. Cancer, in particular, can look and progress differently depending on the individual person. That’s why every patient ideally also needs a customized treatment that is tailored to their individual needs. But how feasible is this idea?
22/02/2018Here on Earth, all experiments are bound by gravitation. Yet, freed from gravity's grip, tumor cells, for example, behave in an entirely different way. As part of the "Thyroid Cancer Cells in Space" project by the University of Magdeburg, smartphone-sized containers carrying poorly differentiated thyroid cancer cells are sent into space.
08/01/2018Few patients with heart failure are fortunate enough to receive a donor's heart. Ventricular assist devices (or heart pumps) have been around for several years and are designed to buy time as patients wait for a transplant. Unfortunately, the body doesn't always tolerate these devices.