Organ-on-a-chip - the mini organs of the future? -- MEDICA - World Forum for Medicine

Image: Close-up of a male chest-shoulder area with a tattoo-like drawing on the skin that is supposed to represent a gene cluster; Copyright: Polygraph Design

Polygraph Design

How genes and small molecules influence personal disease risk

25/11/2022

In an international collaboration with partners from Cambridge (UK), scientists from the Berlin Institute of Health at the Charité (BIH) have now discovered more than 300 regions in the genome that contribute to this individual chemical fingerprint. They have now published their results in Nature Medicine.
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FoToArtist_1

Warmer brain-irrigation fluid in surgery more efficacious

25/11/2022

A simple method can halve the number of repeat operations to remedy bleeding under the cranium, a study at the University of Gothenburg shows. The method is based on replacing irrigation fluid at room temperature with fluid at body temperature.
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Tel Aviv University

Ultrasound and nanobubbles allow cancerous tumors to be destroyed

23/11/2022

A new technology developed at Tel Aviv University makes it possible to destroy cancerous tumors in a targeted manner, via a combination of ultrasound and the injection of nanobubbles into the bloodstream.
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University of Oslo

Resistances: these bacteria hide and then take charge

23/11/2022

A doctor discovers bacteria in a sample that is causing a case of pneumonia and prescribes antibiotics. But at the same time, there is another, nastier variant of bacteria lurking in the patient’s body that is very glad to have got rid of its competitor.
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Nikita_Karchevskyi

Tumors: forecasting the risks of brain surgery

22/11/2022

Can surgeons quantify the risk of aphasia when removing a brain tumor? To find out, researchers at Klinikum rechts der Isar of the Technical University of Munich (TUM) are analyzing the brain as a network. In a current study with 60 patients, they already achieved an accuracy rate with three quarters of their predictions.
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Nikita_Karchevskyi

Quantum technology for cancer imaging

21/11/2022

Tracing the metabolism of tumor cells using magnetic resonance imaging (MRI) has not been feasible in routine clinical settings hitherto. Now, an interdisciplinary research team including the Technical University of Munich (TUM) is working to advance the development of a quantum-based hyperpolarizer so that it can be deployed in clinical applications.
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Iakobchuk

MEDICA 2022: Simplifying analysis and visualization of medical image data

15/11/2022

A team of researchers from Kaiserslautern and Leipzig is working on a system that automatically analyses and visualises medical data, including their uncertainties.
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Fraunhofer IBMT/Markus Michel

MEDICA 2022: Biological laboratory to go

10/11/2022

Researchers from the Fraunhofer Institute for Biomedical Engineering IBMT have developed the “BioSensoLab“, a mobile biological laboratory with which they can demonstrate new developments to customers and test them together – on site at their companies.
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BarcelonaTech (UPC)

Maria Pau Ginebra awarded Advanced Grant by ERC

01/11/2022

The European Research Council (ERC) has awarded UPC researcher Maria Pau Ginebra an Advanced Grant to study the mechanisms of biomaterial and bacteria interaction and to develop surfaces that can fight infections and promote bone regeneration.
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Wavebreakmedia

Breathe again: Diaphragm stimulation after prolonged mechanical ventilation

24/10/2022

For the past two years, the Greifswald University Medical Center has been collaborating in an international study in which a therapy using electrostimulation of the diaphragm is designed to wean patients off artificial respiration. The innovative system aims to achieve faster independence from the ventilator.
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Advanced Materials Technologies

Measuring brain activity on the go

24/10/2022

Researchers from The Institute of Scientific and Industrial Research (SANKEN) at Osaka University develop a flexible, wearable and discreet device that can accurately record brain activity in everyday settings.
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Toni Santiso / Rectimepro

Boosting new gas plasma-based treatments for cancer

17/10/2022

Exploring the possibilities of atmospheric-pressure plasmas to develop and consolidate new medical therapies is the main objective of the PlasTHER network, an initiative funded by the European Union under the COST Actions.
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Image: Three men pose; From left to right: Dr. Sergey Korchak, Dr. Stefan Glöggler, and Dr. Henning Schroeder; Copyright: Anna Hübner / Max-Planck-Institut

Anna Hübner / Max-Planck-Institut

Funding for a new method in cancer diagnostics

13/10/2022

An efficient contrast agent method for MRI imaging developed by Max Planck researcher Stefan Gloeggler raises hopes of being able to distinguish tumors from healthy tissue on the basis of their metabolic activity.
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MPI-P

How light can be used to control processes in synthetic cells

12/10/2022

Synthetic – i. e. artificially produced - cells can imitate certain functions of biological cells. These synthetic cells could open up new medical possibilities in the future.
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LIT

Synthetic biosensors reprogram Treg cells to tame autoimmunity and chronic inflammation

10/10/2022

Scientists from the Division of Immunology at the Leibniz Institute for Immunotherapy (LIT) have now developed new types of synthetic biosensors, so-called artificial immune receptors (AIRs), which can be used to reprogram Treg cells into intelligent "smart" Tregs.
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Robert Lea

Modelling the use of Beta Radiation in cancer treatment

27/09/2022

A new paper pits the gold standard simulation method used to calculate the interaction of the ionizing radiation with matter and estimate the radiation dose delivered to a target organ against an alternative analytic method, the Loevinger formula.
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DC_Studio

Project GLADIATOR - New technologies for cancer monitoring and therapy

21/09/2022

The Fraunhofer Institute for Biomedical Engineering IBMT is contributing its expertise in the field of medical biotechnology and ultrasound to an EC project to work on the next generation of theranostics for brain pathologies using autonomous externally controllable nanonetworks.
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Image: A photo in a dark room with weak green light shows a novel biohybrid sensor technology; Copyright: Fraunhofer IPA

Fraunhofer IPA

Biointelligent sensor for measuring viral activity

16/09/2022

Fraunhofer IPA is the overall coordinator of the European biointelligence project BioProS, which is funded with over 6 million euros as part of the HORIZON Europe programme. In this project, a biointelligent sensor for measuring viral activity for the production of therapeutics is being developed.
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Image: Electron microscopic image of Mycobacterium tuberculosis; Copyright: 4.0/Finci, I. et al.

4.0/Finci, I. et al.

Personalised antibiotic treatment strategies for tuberculosis patients

16/09/2022

In an international study presented in the journal Lancet Microbe, DZIF researchers have now succeeded in identifying patient-specific resistance patterns using a bacterial genome analysis technique.
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Image: A cardiologist looks after a study participant during an MRI scan; Copyright: Uwe Dettmar

Uwe Dettmar

Long COVID: persistent heart inflammation might explain heart symptoms

15/09/2022

The research team led by Dr Valentina Puntmann and Professor Eike Nagel from University Hospital Frankfurt and Goethe University Frankfurt followed up around 350 study participants without previously known heart problems who had recovered from a SARS-CoV-2 infection.
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senencov

Stimulation of vagus nerve strengthens communication between stomach and brain

14/09/2022

A research team led by Prof. Dr. Nils Kroemer of the University Hospitals of Tübingen and Bonn has shown for the first time that non-invasive stimulation of the vagus nerve at the ear can strengthen the communication between stomach and brain within minutes.
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stevanovicigor

New diagnostic option for rare eye disease

06/09/2022

Researchers at the Ophthalmology Department at the University of Bonn have tested color-coded fundus autofluorescence as a supportive novel diagnostic method. Fluorescence of the retina can be used to infer the uveitis subtype.
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insidecreativehouse

Work interruptions have a greater impact on older people

05/09/2022

With the help of EEG evaluations, researchers from the Leibniz Research Centre for Working Environment and Human Factors in Dortmund (IfADo) have studied attentional selection during the resumption of primary tasks in younger and older persons in more detail.
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Tel Aviv University

Musical tests can detect mental deterioration in old age

29/08/2022

Researchers have developed a method that employs musical tests and a portable instrument for measuring brain activity to detect cognitive decline in old age.
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Image: diagnostic test on a table; Copyright: beta web GmbH/Melanie Prüser

beta web GmbH/Melanie Prüser

Single-use tests: sensitivity and easy use combined for diagnostics

12/12/2019

Diagnostic testing usually takes some time and a sterile environment to get the results. To cut down on the costs and effort spend on these tasks there are different diagnostic tests. One of them are single-use tests offered by SensDx S.A. The technology behind them not only makes the process faster and easier, but provides the opportunity to expand into home use in the future as well.
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Image: white flat sensor module: the smart care plaster moio.care; Copyright: MOIO GmbH

Wearables: more freedom with the smart care patch

02/12/2019

Too many people in need of care and not enough health care professionals – we all know the problem. For years, research is underway to find digital solutions for AAL to support the growing number of older & sick adults. These new technologies aim to both alleviate caregiver burden and enhance everyday life of people in need of care with a minimum level of constraint whilst promoting independence.
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Image: several people standing around a bed with a stand-up function on which one person sits; Copyright: Ralf Lienert/Allgäuer Zeitung

AAL Living Lab: research, education and raising awareness

02/12/2019

Smart home systems are a perfect example of how technology can make our daily lives easier. The fact that they can use a tablet to adjust lighting and blinds in every room benefits older adults in more ways than one. These types of technical systems are a part of Ambient Assisted Living (AAL) and create a safe living environment for older persons.
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Image: elderly woman with a tablet on her lap; Copyright: panthermedia.net/Lev Dolgachov

Ambient Assisted Living: sensors for seniors

02/12/2019

Our ageing society is confronted with fewer and fewer workers. One of the many consequences is a shortage of skilled nursing staff. Ambient Assisted Living should solve this problem. By equipping the living environment of elderly people or people in need of care with (technical) assistance systems, they are to be given more self-determination and security. The nursing staff also benefits.
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Image: elderly woman in a wheelchair showing a nurse something on a tablet; Copyright: panthermedia.net/mark@rocketclips.com

Smart care: safety and support thanks to AAL

02/12/2019

Average life expectancy keeps increasing, while birth rates are declining – at least when it comes to most industrial nations. The coming decades will see a decreasing number of gainfully employed people versus more and more senior citizens and people in need of care. It's a trend that already pushes healthcare to the brink. That's why we desperately need new concepts. One of them is AAL.
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panthermedia.net/olanstock

Cardiac diagnostics – prompt and personalized

08/11/2019

If physicians suspect an acute myocardial infarction, they first order an ECG. This test is very established and allows cardiologists to quickly diagnose acute heart attacks – though the test does not detect less common heart attack symptoms. So far, those patients had to wait up to twelve hours before a heart attack could be accurately diagnosed or ruled out. But things are about the change.
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Medicine at the pulse of time: Innovations and trends at MEDICA 2019

04/11/2019

Soon, the world's largest trade fair for medical technology will open its doors again: More than 5.000 exhibitors will present their newest products and ideas at MEDICA from 18 to 21 November. You will not only meet well-known companies here, but also lots of young start-ups. Or, you can visit the MEDICA forums and conferences to experience a rich program of lectures and discussions.
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Image: Volker Bruns; Copyright: Fraunhofer ISS

Fraunhofer ISS

AI software: "iSTIX opens your world to the possibilities of digital pathology"

08/10/2019

The healthcare market offers a multitude of microscopes that make cells visible to the human eye. The same applies to AI-based software for image analysis. After taking the microscopic images, scientist are faced with large volumes of scans with usually low resolution. Yet when all aspects merge together, they open up a the world of digital pathology.
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MEDICA START-UP PARK: "For those, who want to experience the startup-spirit"

01/10/2019

When the halls of MEDICA are open to the world to showcase medical innovations, one joint exhibition booth is guaranteed to attract special attention - the MEDICA START-UP PARK. The startups that present their advances in this setting are interesting to visitors and investors, yet long-time exhibitors and big businesses can also benefit from building relationships with these young companies.
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MEDICA START-UP PARK 2019: Experience tomorrow's innovations today

01/10/2019

The medical market is booming - medical ideas and visions for the future are more in demand than ever. Especially at MEDICA START-UP PARK 2019 young founders want to present their product innovations. Develop business contacts, meet investors and experience an international environment in just one place. Discover in our Topic of the Month what makes MEDICA START-UP PARK unique.
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Telemedicine: easy breathing with AI for respiratory tract

01/10/2019

Pneumonia, COPD or cystic fibrosis – people with such lung diseases have to consult their doctor regularly. Little children have to undergo certain measurements by the doctor, too. In order to save people`s need to visit a doctor, telemedicine offers many ways to do examinations at home.
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panthermedia.net/kasto

Cardiac Tissue Engineering: a heart out of the Petri dish

23/09/2019

For patients waiting for donor organs, every day can mean the difference between life and death. Making things even more complicated is the fact that not every organ is a compatible match with the patient. It would mean enormous progress if we could grow organs from the patient's own cells in the lab. That's why patients with heart disease place big hope in tissue engineering.
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Image: Robot points with his finger at CT images of the brain, in the background a CT device; Copyright: panthermedia.net/phonlamai

Man vs. machine – the benefits of AI in imaging

02/09/2019

Radiology is a field that produces large volumes of data, which can no longer be managed without the help of intelligent systems. This is especially true when it comes to the interpretation of medical images. While this takes physicians years of training and experience, several hours of work and the highest level of concentration, AI only requires a few seconds to accomplish the same task.
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Image: Robot looks at huge amount of CT images of the brain; Copyright: panthermedia.net/phonlamai

AI in imaging: how machines manage our Big Data

02/09/2019

In modern medicine, especially in the field of imaging, huge amounts of data are produced – so much that radiologists can hardly keep up with diagnosing the images. Artificial Intelligence could be the solution to this problem. But how exactly can it help in this task? How can man and machine work together? And what else will be possible in the future with the support of intelligent systems?
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Image: CT image of the lungs with AI-supported automatic highlighting, quantification and measurement of anatomy and deviations; Copyright: Klinikum Nürnberg

AI in radiology: reliable partner for diagnosing CT images

02/09/2019

More patients, more examinations, more CT images – in radiology there is too much work for too few physicians. CT scans are evaluated in the shortest possible time, which leads to anomalies being overlooked. Artificial intelligence, on the other hand, works with constant speed and performance, which is why radiological routine increasingly relies on its support.
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German Medical Award

German Medical Award 2019 celebrates the future of (patient) care

22/08/2019

The German Medical Award will take place on November 18, 2019, as part of the MEDICA trade fair in Düsseldorf. The ceremony emphasizes the commitment to excellence in cutting-edge care for patients. Doctors, clinical centers and companies in the medical and healthcare industry can demonstrate their achievements in medicine and management in hopes of receiving the coveted award.
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Leibniz-IPHT/Sven Döring

Tumor excision: triple imaging for unique diagnostics

08/08/2019

After their tumor has been removed, some patients have to return to the hospital to undergo surgery again. That's because the tumor was not precisely identified and was subsequently not completely removed. That's both an ethical and financial dilemma. A new surgery-adjacent procedure is designed to rapidly and accurately detect tumors.
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Image: Two petri dishes with different kinds of agar plates on which bacterial cultures are growing; Copyright: panthermedia.net/photographee.eu

Antibiotic resistance: technical tricks against pathogens

01/08/2019

An untreatable infection is a nightmare for physicians and potentially life-threatening to the patient. Unfortunately, more and more pathogens emerge that are resistant to drugs, especially antibiotics. We need to use our drugs smartly and come up with technical solutions as well to prevent our weapons from blunting in the future.
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Image: Flags; Copyright: SilverSky LifeSciences GmbH

SilverSky LifeSciences GmbH

Striking new paths in medicine - Diagnostics Partnering Conference 2019

08/07/2019

On November 18th, 2019, parallel to the first day of MEDICA, the world forum for medicine, the Diagnostics Partnering Conference (DxPx Conference) will take place in Düsseldorf, bringing together stakeholders in the diagnostics and research tool industry. The DxPx Conference focuses on discovering technologies, finding financing and investment opportunities and forming collaborative partnerships.
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Performance diagnostics: success in sports – testing the limits of performance

01/07/2019

Stationary or mobile - competitive athletes rely on regular health assessments. They must deliver peak performance and be physically fit during competitions. But when do they reach their physical limits? Are there any devices that provide information, no matter where the test subject is located?
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Image: Sports shoes of an athlete; Copyright: panthermedia.net/ Daxiao_Productions

Sports medicine - performance values in best health

01/07/2019

Those who integrate physical activities into their own lifestyle live healthier and more balanced. But where are the physical limits? Can health status measurements also be carried out on the road? Discover more about how sports medical examinations contribute to maintain performance and minimize health risks in our Topic of the Month.
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Image: Marathon runner; Copyright: panthermedia.net/adamgregor

Sports medicine – keep moving to stay healthy

01/07/2019

Physical activity plays a big role in today's society. Whether you are an amateur or professional athlete – incorporating exercise into your life positively impacts your mental and physical health. Ideally, sport should be fun, pressure-free and not overburden you. But can you measure individual performance and align it with sports?
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Image: Team Capsix with KUKA robot arm and body model; Copyright: Capsix Robotics, Lyon

Capsix Robotics, Lyon

Healthy Living thanks to robotics – KUKA Innovation Award 2019

24/06/2019

Improving technology transfer from research to industry and driving robotics development - that's the idea behind the KUKA Innovation Award. This year’s topic is "Healthy Living". Applicants from around the world were tasked with creating a robot application for healthcare settings. Now, the finalists, who will showcase their innovations at the MEDICA 2019 trade fair have been selected.
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Image: Woman uses robot arm to grab something on the table; Copyright: RWTH Aachen/RPE & inRehaRob

Of exoskeletons and service robots – the future of rehabilitation

03/06/2019

For most people, enjoying a good quality of life means having the ability to move freely, safely and independently. Intensive and costly rehabilitation is needed if this is no longer an option after a stroke for example. We are introducing some projects that deliver innovative robotic solutions.
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Image: Boy with robotic gait trainer on treadmill; Copyright: panthermedia.net/olesiabilkei

Robotics – rehab with motors and sensors

03/06/2019

They work with power, precision and tirelessly. This makes robots an ideal instrument for rehabilitation. In gait or motor training, movement sequences must be repeated thousands of times so that they can be learnt anew. What tires the patient and costs the therapist's time can easily be managed by robot-assisted systems. Learn more about the possibilities of robotics in rehabilitation.
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Image: triangular table at which three patients do various robotic rehabilitation exercises; Copyright: Hocoma, Switzerland

Walking is an issue of mind over matter – how robots assist rehabilitation

03/06/2019

Humans are living longer than ever but still want to continue to live independently as they age. Meanwhile, our motor and cognitive abilities decline as we age, sometimes as the effects of a stroke. The number of people in need of long-term care is growing at breakneck speed. At the same time, fewer and fewer young people choose stressful careers as caregivers.
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Image: Wrist with smartwatch, which measures the pulse rate; Copyright: panthermedia.net / Lev Dolgachov

panthermedia.net / Lev Dolgachov

mHealth: Atrial fibrillation detection – App supports heart health

08/05/2019

Atrial fibrillation is the most common type of persistent cardiac arrhythmia (irregular heart rhythm). Researchers estimate that 1.8 million Germans are presently affected by this disease. The condition is difficult to diagnose, frequently goes undetected and may result in a stroke. A new smartwatch medical app is designed to help patients detect atrial fibrillation before it’s too late.
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Image: Patient during an fMRI examination; Copyright: panthermedia.net/Chris De Silver

Functional imaging: what makes the brain tick?

01/04/2019

Our brain is the command center of our body. This is where all information and impressions are collected and converted into responses and movements. Modern imaging techniques offer physicians and researchers unique insights into the actions of the human central nervous system. The functional imaging technique allows them to watch our brain in action.
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Image: CT scan open; Copyright: panthermedia.net/SimpleFoto

Functional imaging: a look at the command center

01/04/2019

All information from our body and the environment converges in our brain and is transformed into reactions in milliseconds. It is essential for medicine and research to know what our switching centre looks like. Functional methods are used to observe it more closely during work.
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Image: Dosage inhaler and stethoscope in front of a shelf; Copyright: panthermedia.net/liudmilachernetska@gmail.com

React early, breathe free – comprehensive COPD management

01/03/2019

COPD is considered the third most common cause of death worldwide and mainly affects smokers. It is not curable, but with the right combination of early diagnosis, therapy and self-management, a significant part of the quality of life can be regained. The comprehensive care is supported by various devices and technical tools. Learn more about the all-round care of COPD in our Topic of the Month.
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Image: Preemie doll with drug delivery system on the nose; Copyright: Fraunhofer ITEM/Till Holland

Fraunhofer ITEM/Till Holland

Gentle medication for the little ones – with every breath

22/02/2019

According to the WHO, ten percent of babies worldwide are born prematurely. Since most organs of these tiny babies have not fully developed yet, it can quickly lead to complications and disorders and most notably affect the lungs of the premature infants. What's more, infections require gentle treatment, as the preemies themselves are fragile and susceptible – making this a challenging situation.
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Image: Graphic rendering of several cells in a petri dish; Copyright: panthermedia.net/dani3315

Organ-on-a-chip systems: limited validity?

01/02/2019

Organ-on-a-chip systems are technically a great enhancement of medical research because they facilitate testing of active ingredients on cell cultures in the chambers of a plastic chip. This replaces animal testing and improves patient safety. That being said, they are not a true-to-life replication of the human body and can only simulate a few functions and activities.
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Image: Cells in a Petri dish; Copyright: panthermedia.net / devserenco

Organ-on-a-chip - the mini organs of the future?

01/02/2019

So far in vitro methods and animal experiments have been used to determine the causes of diseases, research therapeutic approaches and predict the effect of drugs. Organ-on-a-chip models now offer a more accurate and ethically justifiable alternative. Find out more about the models, their advantages and future developments in our Topic of the Month.
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Image: Man and woman in a laboratory presenting a multi-organ chip; Copyright: TissUse GmbH

Multi-Organ Chips – The Patients of Tomorrow?

01/02/2019

The liver, nervous tissue or the intestines: all are important human organs that have in the past been tested for their function and compatibility using animal or in vitro test methods. In recent years, TissUse GmbH, a spin-off of the Technical University of Berlin (TU Berlin), has launched multi-organ chip platforms. But that’s not all.
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Image: Cell cultivation in a Petri dish; Copyright: panthermedia.net / matej kastelic

Organ-on-a-chip – Organs in miniature format

01/02/2019

In vitro processes and animal tests are used to develop new medications and novel therapeutic approaches. However, animal testing raises important ethical concerns. Organ-on-a-chip models promise to be a feasible alternative. In a system the size of a smartphone, organs are connected using artificial circulation.
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Image: Woman at her desk holding her back; Copyright: panthermedia.net/Andrey Popov

panthermedia.net/Andrey Popov

AI ensures dynamic sitting

22/01/2019

Whether in the office, at school or behind the wheel: we spend a lot of time sitting and often stay in the same position for too long. The possible side effects are stiffness, back problems and pain. The SensA-Chair smart seating solution combats decreased mobility and ensures dynamic sitting.
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Image: Sock TelePark; Copyright: Marc Eisele, University Hospital Dresden

Marc Eisele, Universitätsklinikum Dresden

Better living thanks to telemedicine – "TelePark"- project targets patients with Parkinson’s disease

08/01/2019

Parkinson's disease is a progressive nervous system disorder that primarily affects movement of patients and makes their everyday lives very challenging. It also makes regular doctor appointments and treatment sessions necessary. "TelePark" - a project that collects different movement-related parameters using sensors and apps is designed to improve the quality of life for Parkinson’s patients.
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Image: digital capture of an eye; Copyright: panthermedia.net / cosmin momir

A digital look inside the human eye – when algorithms diagnose Diabetes

02/01/2019

Diabetes mellitus or simply diabetes has become very common and is often described as a lifestyle disease. More and more people are suffering from this chronic metabolic disorder. Next to established diagnostic procedures, digital retinal screening has shown to be successful - a promising technique that will also play an important role in the diagnosis of other diseases in the future.
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Image: Woman with diabetes and a sensor; Copyright: panthermedia.net / Click and Photo

Blood glucose monitoring of tomorrow - modern diabetes therapies

02/01/2019

There are 425 million people with diabetes in the world. Heart problems, kidney failure or blindness - these can all be consequences of the metabolic disease. Diabetes patients now have the possibility of being treated digitally.
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