Medicine at the pulse of time: Innovations and trends at MEDICA 2019 -- MEDICA - World Forum for Medicine

Image: Close-up of a brain MRI scan result; Copyright: Rawpixel

Rawpixel

Brain tumor cells invade the brain as neuronal free riders

08/08/2022

Scientists at Heidelberg University Hospital, Heidelberg University and the German Cancer Research Center have discovered an elementary new spreading strategy in gioblastomas, the most aggressive of all brain tumors.
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Image: Two smiling men are standing in front of a large, box-shaped device with a glass front – Prof. Niels Voigt, Dr. Thomas Mager; Copyright: mbexc

mbexc

Unique technology platform for cellular electrophysiology and optogenetics

26/07/2022

Electrical activity is one of the most important common features of the heart and the brain. The goal of the Göttingen Cluster of Excellence "Multiscale Bioimaging: From Molecular Machines to Networks of Excitable Cells (MBExC)" is to understand the functional properties of cardiomyocytes and neurons, which form the smallest electrically active units of both organs.
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Image: Photographed microscope in a laboratory; Copyright: svitlanah

svitlanah

Individual cells are smarter than thought

25/07/2022

Humans make decisions based on various sensory information which is integrated into a holistic percept by the brain. But how do single cells make decisions? Much more autonomously than previously thought, as researchers from the University of Zurich have now shown.
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Image: A side by side comparison of moles on a patient's back (right) and the same moles as star-like targets in the astronomical software used by the MoleGazer ; Copyright: The MoleGazer Team

The MoleGazer Team

MoleGazer: Applying astronomy ideas to mole identification

21/07/2022

Scientists are applying astronomical techniques to identify moles that may develop into the skin cancer melanoma. Astronomers regularly take images of the sky, producing software to map set targets over time. This technology is now being adapted to monitor the evolution of moles in high-risk patients.
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Image: An image composed of colorful dots that form an arc; Copyright: abberior Instruments

abberior Instruments

Neurology: molecular map of the synapse

19/07/2022

Scientists at the Institute for Auditory Neuroscience, UMG, the Max Planck Institute for Multidisciplinary Sciences and the abberior Instruments GmbH apply high-resolution 3D-MINFLUX technology for precise 3D representation of the molecular organization in the active zone of rod photoreceptor cells.
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Image: Scientist working in a laboratory; Copyright: twenty20photos

twenty20photos

New material paves the way for remote-controlled medication and electronic pills

23/06/2022

Biomedicines are produced by living cells and are used to treat cancer and autoimmune diseases among other things. One challenge is that the medicines are very expensive to produce, something that limits global access. Now researchers from Chalmers have invented a material that uses electrical signals to capture and release biomolecules.
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Image: A smiling man is sitting behind a laboratory device; Copyright: Universität Bielefeld/M.-D. Müller

Universität Bielefeld/M.-D. Müller

Making drug interactions in the liver visible

15/06/2022

Bielefeld University is coordinating a new EU-research project that seeks to produce microscopic liver tissue cultures that can survive for 14 days, while also using imaging methods to investigate how liver cells react to combinations of different medications.
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Image: A hand is holding an object tray with the word “coronavirus” on it in front of a microscope and a screen; Copyright: mstandret

mstandret

Identifying viruses more quickly

14/06/2022

The research project NanoXCAN involving Leibniz Universität Hannover aims to revolutionize virus imaging technology. The European Commission is funding the project with around 4 million euros. Every hospital could benefit, as a rapid and reliable identification of viral subtypes can save lives.
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Image: Drawing of a liver that is connected to a magnifying glass by colorful circles; Copyright: Lili Niu © Novo Nordisk Foundation, Center for Protein Research

Lili Niu © Novo Nordisk Foundation, Center for Protein Research

Early diagnosis of liver diseases by proteomics

06/06/2022

Two or three drinks every day could put your liver in danger. Using proteomics and machine learning, researchers now present a revolutionary tool to predict whether an individual has alcohol-related liver disease and if an individual patient is at risk of disease progression.
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Image: Drawn schematic of a work flow in a laboratory; Copyright: Juliet Percival/MPI für Biochemie

Juliet Percival/MPI für Biochemie

New method revolutionizes cancer diagnosis

24/05/2022

A German-Danish team led by Prof. Matthias Mann has developed a ground-breaking technology called 'Deep Visual Proteomics'. This method provides researchers and clinicians with a protein read-out to understand cancer at single cell-type resolution. The technology was published in the journal Nature Biotechnology and demonstrates its potential in a first application to cancer cells.
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Image: A three-dimensional view of cell activities of skin cancer squamous cell carcinoma.; Copyright: M. Schober/E. Fuchs, Rockefeller University

M. Schober/E. Fuchs, Rockefeller University

New method melds data to make a 3-D map of cells’ activities

20/05/2022

HZI researchers develop molecular probes to detect pathogens in clinical samples.
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Image: Electron micrograph of Staphylococcus aureus; Copyright: HZI/Manfred Rohde

HZI/Manfred Rohde

A bright spot for microbiological diagnostics

19/05/2022

HZI researchers develop molecular probes to detect pathogens in clinical samples.
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Image: A woman is pushed into an MRI; Copyright: Wavebreakmedia

Wavebreakmedia

Hyperpolarized nuclear MR: more precise diagnoses and personalized therapies

17/05/2022

Hyperpolarized nuclear magnetic resonance enables major medical advances in molecular diagnostics, for example for cardiovascular diseases or cancer therapy. Within the framework of the EU collaborative project "MetaboliQs", seven partners developed a microscopy method which enables the analysis of metabolic processes at the single cell level by means of diamond-based hyperpolarization.
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Image: Assembly of biochips with attached tubes; Copyright: Fraunhofer ILT, Aachen

Fraunhofer ILT, Aachen

Process chains for isolation and analysis: from single cells to organoids

17/05/2022

Researchers at the Fraunhofer Institute for Laser Technology ILT are working on new tools for the preparation and analysis of single cells and cell assemblies. The team developed the "Liftoscope", a system for cell sorting for subsequent cultivation that can analyze and transfer biomaterials precisely and in a way that is gentle on cells.
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Image: A man wearing VR glasses stands in front of a screen and looks at a protein structure; Copyright: The University of Texas at San Antonio

The University of Texas at San Antonio

Virtual reality to give UTSA students unique look at proteins

16/05/2022

Francis Yoshimoto, assistant professor in the UTSA College of Sciences’ Department of Chemistry, is introducing his Biochemistry II laboratory students to a new way of learning—using virtual reality headsets to observe and analyze protein structures.
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Image: Preview picture of video

What intensive care patients really need – Communication via eye-tracking systems

07/04/2022

Patients at the intensive care unit are not always able to communicate with their environment, even if they are conscious. The BG University Hospital Bergmannsheil in Bochum, Germany, now aims to enable them to communicate using an eye-tracking system. Learn in our video interview how this system works, how it was established and what obstacles still need to be overcome.
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Image: Two screens with picture of the circulatory system in a catheter laboratory; Copyright: panthermedia.net/sudok1

MEDICA TECH FORUM: light-based imaging technique OCT

04/11/2019

Since its inception, MEDICA TECH FORUM has focused on the implementation of innovations and new technologies into clinical practice. 2019 marks the tenth year of the Forum. In honor of its anniversary, we will brighten things up a bit, as one of the focal points will highlight how optical coherence tomography (OCT) uses light to produce images.
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Image: Volker Bruns; Copyright: Fraunhofer ISS

Fraunhofer ISS

AI software: "iSTIX opens your world to the possibilities of digital pathology"

08/10/2019

The healthcare market offers a multitude of microscopes that make cells visible to the human eye. The same applies to AI-based software for image analysis. After taking the microscopic images, scientist are faced with large volumes of scans with usually low resolution. Yet when all aspects merge together, they open up a the world of digital pathology.
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Image: DLIR image of the aorta; Copyright: GE Healthcare

Deep Learning Image Reconstruction – what AI looks like in clinical routine

02/09/2019

Artificial intelligence is no longer a dream of the future in medicine. Many studies and initial application examples show that it sometimes achieves better results than human physicians. At Jena University Hospital, the work with AI is already lived practice. It is the first institution in the world to use algorithms in radiological routine to reconstruct CT images.
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Image: Laboratory situation - Prof. Popp shows a young man a small object in his hand; Copyright: Leibniz-IPHT/Sven Döring

Leibniz-IPHT/Sven Döring

Tumor excision: triple imaging for unique diagnostics

08/08/2019

After their tumor has been removed, some patients have to return to the hospital to undergo surgery again. That's because the tumor was not precisely identified and was subsequently not completely removed. That's both an ethical and financial dilemma. A new surgery-adjacent procedure is designed to rapidly and accurately detect tumors.
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Image: A greenly lit laboratory device; Copyright: Sven Döring

Photonics: "We want a rapid and easy method to identify pathogens and antibiotic resistance"

01/08/2019

The medical devices value chain has gaps between academic research and industrial practice that slow down innovation processes. This also applies to time-sensitive and urgently needed products such as rapid diagnostic tests to identify resistant pathogens. At the InfectoGnostics Research Campus in Jena, partners from research and medicine team up to close these gaps.
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Image: Team Capsix with KUKA robot arm and body model; Copyright: Capsix Robotics, Lyon

Capsix Robotics, Lyon

Healthy Living thanks to robotics – KUKA Innovation Award 2019

24/06/2019

Improving technology transfer from research to industry and driving robotics development - that's the idea behind the KUKA Innovation Award. This year’s topic is "Healthy Living". Applicants from around the world were tasked with creating a robot application for healthcare settings. Now, the finalists, who will showcase their innovations at the MEDICA 2019 trade fair have been selected.
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Image: Screenshot of the VR app: a small penguin sitting on the treatment table of the MRI device; Copyright: Entertainment Computing Group, Uni DUE & LAVAlabs Moving Images

Entertainment Computing Group, Uni DUE & LAVAlabs Moving Images

Gamification: how penguins help children overcome their MRI fear

23/04/2019

It's noisy, tight and scary - that's how children feel about a magnetic resonance imaging (MRI) machine. Because they are scared, they are often too fidgety and anxious during the procedure, causing the images to blur or the scan to be stopped. Researchers have now developed a VR app called Pingunauten Trainer that’s designed to gently prepare the little patients for MRI scans.
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Image: Patient during an fMRI examination; Copyright: panthermedia.net/Chris De Silver

Functional imaging: what makes the brain tick?

01/04/2019

Our brain is the command center of our body. This is where all information and impressions are collected and converted into responses and movements. Modern imaging techniques offer physicians and researchers unique insights into the actions of the human central nervous system. The functional imaging technique allows them to watch our brain in action.
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Image: close-up of a woman lying in an MRI device; Copyright: panthermedia.net/Craig Robinson

Brain mapping: preoperative planning with functional MRI

01/04/2019

A surgery already begins before the patient is lying on the operating table – namely with the planning. For example, if brain surgery is imminent, the brain must first be mapped. This makes the activity level of certain brain areas visible. Functional magnetic resonance imaging makes this possible.
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Image: Man during CT examination; Copyright: panthermedia.nt/Romaset

Stroke: 4D brain perfusion accelerates treatment

01/04/2019

In an ischaemic stroke, rapid treatment is essential. In this moment good imaging data is particularly important to enable doctors to make the best possible decision for therapy. Modern CT scanners are increasingly being used to assess stroke patients because they can show the blood flow to the brain over time.
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Image: CT scan open; Copyright: panthermedia.net/SimpleFoto

Functional imaging: a look at the command center

01/04/2019

All information from our body and the environment converges in our brain and is transformed into reactions in milliseconds. It is essential for medicine and research to know what our switching centre looks like. Functional methods are used to observe it more closely during work.
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Picture: Woman sleeping sideways in bed with a breathing mask; Copyright: Philips GmbH

Comprehensive Treatment: It’s All About Breathing

01/03/2019

Coughing, airway obstruction, difficulty breathing: Chronic obstructive pulmonary disease (COPD) is an umbrella term used to describe progressive and currently incurable lung diseases. The innovative solutions of Philips Respironics help patients to manage each stage of the disease and their medication intake, train the respiratory system and provide respiratory support.
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Image: Dosage inhaler and stethoscope in front of a shelf; Copyright: panthermedia.net/liudmilachernetska@gmail.com

React early, breathe free – comprehensive COPD management

01/03/2019

COPD is considered the third most common cause of death worldwide and mainly affects smokers. It is not curable, but with the right combination of early diagnosis, therapy and self-management, a significant part of the quality of life can be regained. The comprehensive care is supported by various devices and technical tools. Learn more about the all-round care of COPD in our Topic of the Month.
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Image: Lung monitoring of a patient with PulmoVista 500 by Draeger; Copyright: Drägerwerk AG & Co. KGaA

Restoring Pulmonary Function

01/03/2019

People suffering from lung disease temporarily need ventilator support because they are unable to breathe naturally. Mechanical ventilation is designed to ensure the survival of these patients. The goal is to adapt the ventilator settings and tailor them the patient's specific needs and prevent lung tissue damage.
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Image: Man and woman in a laboratory presenting a multi-organ chip; Copyright: TissUse GmbH

Multi-Organ Chips – The Patients of Tomorrow?

01/02/2019

The liver, nervous tissue or the intestines: all are important human organs that have in the past been tested for their function and compatibility using animal or in vitro test methods. In recent years, TissUse GmbH, a spin-off of the Technical University of Berlin (TU Berlin), has launched multi-organ chip platforms. But that’s not all.
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Image: Cells in a Petri dish; Copyright: panthermedia.net / devserenco

Organ-on-a-chip - the mini organs of the future?

01/02/2019

So far in vitro methods and animal experiments have been used to determine the causes of diseases, research therapeutic approaches and predict the effect of drugs. Organ-on-a-chip models now offer a more accurate and ethically justifiable alternative. Find out more about the models, their advantages and future developments in our Topic of the Month.
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Image: digital capture of an eye; Copyright: panthermedia.net / cosmin momir

A digital look inside the human eye – when algorithms diagnose Diabetes

02/01/2019

Diabetes mellitus or simply diabetes has become very common and is often described as a lifestyle disease. More and more people are suffering from this chronic metabolic disorder. Next to established diagnostic procedures, digital retinal screening has shown to be successful - a promising technique that will also play an important role in the diagnosis of other diseases in the future.
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Image: Woman with diabetes and a sensor; Copyright: panthermedia.net / Click and Photo

Blood glucose monitoring of tomorrow - modern diabetes therapies

02/01/2019

There are 425 million people with diabetes in the world. Heart problems, kidney failure or blindness - these can all be consequences of the metabolic disease. Diabetes patients now have the possibility of being treated digitally.
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