manjurulhaque
Analyzing disease progression and cell processes with TIGER: in vivo and non-invasively
18/01/2023
Researchers at the Helmholtz Institute for RNA-based Infection Research (HIRI) and the Julius-Maximilians-Universität (JMU) in Würzburg have developed a technology they call TIGER. It allows complex processes in individual cells to be deciphered in vivo by recording past RNA transcripts.
Amac Garbe/Fraunhofer IWS
Radioactive substances fight cancer in the mini-lab
13/01/2023
Two Dresden research institutes want to reduce the number of animal experiments in radiopharmaceutical research with a new idea.
Aalto University
Gaining unprecedented view of small molecules by machine learning
06/01/2023
A new tool to identify small molecules offers benefits for diagnostics, drug discovery and fundamental research. A new machine learning model will help scientists identify small molecules, with applications in medicine, drug discovery and environmental chemistry.
XiXinXing
Map of the brain's- and cerebrospinal fluid's immune cells
21/12/2022
Neuroscientists from the University of Münster have now generated an atlas that could change this: using it will allow to better understand disease mechanisms and to study the effects of therapies in a new way. This invaluable resource is provided as a freely available software for researchers all around the world.
westend61
Ground-breaking new method for multi-cancer early detection
16/12/2022
An international study led by researchers from Chalmers University of Technology, Sweden, shows that a new, previously untested method can easily find multiple types of newly formed cancers at the same time – including cancer types that are difficult to detect with comparable methods.
Fraunhofer ITEM
Designer immune cells for drug discovery, potency and safety testing
14/12/2022
Fraunhofer researchers have succeeded in scaling the production of customized immune cells from laboratory up to industrial level.
Völkner et al., Nat. Comm., 2022
Macular degeneration: new potential mechanism for vision loss discovered
09/12/2022
Thanks to laboratory produced human mini-retinas, researchers were able to observe complex changes in the retina as they occur in macular degeneration. This enabled them to discover the so-called cell extrusion as a potential mechanism for neurodegenerative diseases.
NUS Institute for Health Innovation & Technology
New cancer testing method makes regular monitoring affordable
09/12/2022
Scientists from the National University of Singapore (NUS) have discovered a novel low-cost method of testing for cancers. Called the Heatrich-BS assay, this new test sequences clinical samples that have been heated in order to isolate cancer-specific signatures found in a patient’s blood.
mstandret
Why are overweight people more susceptible to illness?
07/12/2022
If you gain weight, the fat cells in the body get bigger. So in the extremely obese, those fat cells are greatly enlarged. Now, researchers from the Technical University of Munich (TUM) were able to show how enlarged fat cells can cause metabolic diseases. They also developed non-invasive examination methods to determine the size of human fat cells.
Paul Schütz
How lymph nodes are supplied with blood
07/12/2022
3D images have been obtained that show the vascular system of the nodes with previously unattained resolution.
ktsimage
Sinonasal cancer: AI facilitates breakthrough in diagnostics
30/11/2022
Researchers at LMU and Charité hospital in Berlin have developed a method for classifying difficult-to-diagnose nasal cavity tumors.
Keisuke Ishihara
Measuring organ development
28/11/2022
Researchers from Dresden and Vienna reveal link between connectivity of three-dimensional structures in tissues and the emergence of their architecture to help scientists engineer self-organising tissues that mimic human organs.
Empa
Empa's Zukunftsfonds – Funding ambitious research: A chip to replace animal testing
24/11/2022
New drugs made from nanoparticles that can easily penetrate any interface within our bodies are a great hope in medicine. For such hopefuls to reach the market, their safety must be ensured. In this context, it must also be clarified what happens if a substance manages to penetrate the natural barrier between baby and mother, the placenta, in the body of pregnant women.
Tohoku University
Sensing platform for studying in vitro vascular systems
11/11/2022
The costliness of drug development and the limitations of studying physiological processes in the lab are two separate scientific issues that may share the same solution.
Fraunhofer IBMT/Markus Michel
MEDICA 2022: Biological laboratory to go
10/11/2022
Researchers from the Fraunhofer Institute for Biomedical Engineering IBMT have developed the “BioSensoLab“, a mobile biological laboratory with which they can demonstrate new developments to customers and test them together – on site at their companies.
Fraunhofer ISS
AI software: "iSTIX opens your world to the possibilities of digital pathology"
08/10/2019
The healthcare market offers a multitude of microscopes that make cells visible to the human eye. The same applies to AI-based software for image analysis. After taking the microscopic images, scientist are faced with large volumes of scans with usually low resolution. Yet when all aspects merge together, they open up a the world of digital pathology.
Multi-Organ Chips – The Patients of Tomorrow?
01/02/2019
The liver, nervous tissue or the intestines: all are important human organs that have in the past been tested for their function and compatibility using animal or in vitro test methods. In recent years, TissUse GmbH, a spin-off of the Technical University of Berlin (TU Berlin), has launched multi-organ chip platforms. But that’s not all.
Organ-on-a-chip – Organs in miniature format
01/02/2019
In vitro processes and animal tests are used to develop new medications and novel therapeutic approaches. However, animal testing raises important ethical concerns. Organ-on-a-chip models promise to be a feasible alternative. In a system the size of a smartphone, organs are connected using artificial circulation.
Organ-on-a-chip systems: limited validity?
01/02/2019
Organ-on-a-chip systems are technically a great enhancement of medical research because they facilitate testing of active ingredients on cell cultures in the chambers of a plastic chip. This replaces animal testing and improves patient safety. That being said, they are not a true-to-life replication of the human body and can only simulate a few functions and activities.