18/01/2023Researchers at the Helmholtz Institute for RNA-based Infection Research (HIRI) and the Julius-Maximilians-Universität (JMU) in Würzburg have developed a technology they call TIGER. It allows complex processes in individual cells to be deciphered in vivo by recording past RNA transcripts.
13/01/2023Two Dresden research institutes want to reduce the number of animal experiments in radiopharmaceutical research with a new idea.
06/01/2023A new tool to identify small molecules offers benefits for diagnostics, drug discovery and fundamental research. A new machine learning model will help scientists identify small molecules, with applications in medicine, drug discovery and environmental chemistry.
21/12/2022Neuroscientists from the University of Münster have now generated an atlas that could change this: using it will allow to better understand disease mechanisms and to study the effects of therapies in a new way. This invaluable resource is provided as a freely available software for researchers all around the world.
16/12/2022An international study led by researchers from Chalmers University of Technology, Sweden, shows that a new, previously untested method can easily find multiple types of newly formed cancers at the same time – including cancer types that are difficult to detect with comparable methods.
14/12/2022Fraunhofer researchers have succeeded in scaling the production of customized immune cells from laboratory up to industrial level.
09/12/2022Thanks to laboratory produced human mini-retinas, researchers were able to observe complex changes in the retina as they occur in macular degeneration. This enabled them to discover the so-called cell extrusion as a potential mechanism for neurodegenerative diseases.
09/12/2022Scientists from the National University of Singapore (NUS) have discovered a novel low-cost method of testing for cancers. Called the Heatrich-BS assay, this new test sequences clinical samples that have been heated in order to isolate cancer-specific signatures found in a patient’s blood.
07/12/2022If you gain weight, the fat cells in the body get bigger. So in the extremely obese, those fat cells are greatly enlarged. Now, researchers from the Technical University of Munich (TUM) were able to show how enlarged fat cells can cause metabolic diseases. They also developed non-invasive examination methods to determine the size of human fat cells.
07/12/20223D images have been obtained that show the vascular system of the nodes with previously unattained resolution.
30/11/2022Researchers at LMU and Charité hospital in Berlin have developed a method for classifying difficult-to-diagnose nasal cavity tumors.
28/11/2022Researchers from Dresden and Vienna reveal link between connectivity of three-dimensional structures in tissues and the emergence of their architecture to help scientists engineer self-organising tissues that mimic human organs.
24/11/2022New drugs made from nanoparticles that can easily penetrate any interface within our bodies are a great hope in medicine. For such hopefuls to reach the market, their safety must be ensured. In this context, it must also be clarified what happens if a substance manages to penetrate the natural barrier between baby and mother, the placenta, in the body of pregnant women.
11/11/2022The costliness of drug development and the limitations of studying physiological processes in the lab are two separate scientific issues that may share the same solution.
10/11/2022Researchers from the Fraunhofer Institute for Biomedical Engineering IBMT have developed the “BioSensoLab“, a mobile biological laboratory with which they can demonstrate new developments to customers and test them together – on site at their companies.
08/10/2019The healthcare market offers a multitude of microscopes that make cells visible to the human eye. The same applies to AI-based software for image analysis. After taking the microscopic images, scientist are faced with large volumes of scans with usually low resolution. Yet when all aspects merge together, they open up a the world of digital pathology.
01/02/2019The liver, nervous tissue or the intestines: all are important human organs that have in the past been tested for their function and compatibility using animal or in vitro test methods. In recent years, TissUse GmbH, a spin-off of the Technical University of Berlin (TU Berlin), has launched multi-organ chip platforms. But that’s not all.
01/02/2019In vitro processes and animal tests are used to develop new medications and novel therapeutic approaches. However, animal testing raises important ethical concerns. Organ-on-a-chip models promise to be a feasible alternative. In a system the size of a smartphone, organs are connected using artificial circulation.
01/02/2019Organ-on-a-chip systems are technically a great enhancement of medical research because they facilitate testing of active ingredients on cell cultures in the chambers of a plastic chip. This replaces animal testing and improves patient safety. That being said, they are not a true-to-life replication of the human body and can only simulate a few functions and activities.