Organ-on-a-chip - the mini organs of the future? -- MEDICA - World Forum for Medicine

Image: A man with gray hair and a beard smiles at the camera; Copyright: University of the Basque Country

University of the Basque Country

Micrometric blood plasma separator using high-resolution 3D fabrication

16/12/2022

Researchers at the UPV/EHU-University of the Basque Country have developed a microfluidic plasma separator to optically detect blood biomarkers.
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Image: A man with brown hair in a white coat, Ángel Serrano Aroca, smiles at the camera; Copyright: Asociación RUVID

Asociación RUVID

Biomaterial capable of regenerating bones and preventing infections

15/12/2022

Researchers from the Bioengineering and Biomaterials Laboratory of Universidad Católica de Valencia (UCV) have developed a new porous material capable of regenerating bones and preventing infections at the same time.
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Image: Prof. Lachmann uses different scalable systems to continuously produce specific mature human immune cells from induced pluripotent stem cells.; Copyright: Fraunhofer ITEM

Fraunhofer ITEM

Designer immune cells for drug discovery, potency and safety testing

14/12/2022

Fraunhofer researchers have succeeded in scaling the production of customized immune cells from laboratory up to industrial level.
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Image: Close-up: The complex architecture of the neuroepithelial organoids with cell membranes; Copyright: Keisuke Ishihara

Keisuke Ishihara

Measuring organ development

28/11/2022

Researchers from Dresden and Vienna reveal link between connectivity of three-dimensional structures in tissues and the emergence of their architecture to help scientists engineer self-organising tissues that mimic human organs.
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Image: A woman in the lab, Tina Bürki from Empa's Particles-Biology Interactions lab in St. Gallen, inspects a set of biochips; Copyright: Empa

Empa

Empa's Zukunftsfonds – Funding ambitious research: A chip to replace animal testing

24/11/2022

New drugs made from nanoparticles that can easily penetrate any interface within our bodies are a great hope in medicine. For such hopefuls to reach the market, their safety must be ensured. In this context, it must also be clarified what happens if a substance manages to penetrate the natural barrier between baby and mother, the placenta, in the body of pregnant women.
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Image: A small square apparatus, an electrochemical sensing platform for studying in vitro vascular systems. The channels and reservoirs were visualized using blue ink.; Copyright: Tohoku University

Tohoku University

Sensing platform for studying in vitro vascular systems

11/11/2022

The costliness of drug development and the limitations of studying physiological processes in the lab are two separate scientific issues that may share the same solution.
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Image: Close-up of hands in blue gloves holding left and right petri dishes; Copyright: RossHelen

RossHelen

Inspired by nature: Silencing bacteria

07/11/2022

Cerium dioxide nanoparticles work in biological processes like natural enzymes and change signaling molecules, thereby preventing the formation of biofilms.
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Image: Maria Pau Ginebra in the laboratory smiles at the camera; Copyright: BarcelonaTech (UPC)

BarcelonaTech (UPC)

Maria Pau Ginebra awarded Advanced Grant by ERC

01/11/2022

The European Research Council (ERC) has awarded UPC researcher Maria Pau Ginebra an Advanced Grant to study the mechanisms of biomaterial and bacteria interaction and to develop surfaces that can fight infections and promote bone regeneration.
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Image: Graphic rendering of several cells in a petri dish; Copyright: panthermedia.net/dani3315

Organ-on-a-chip systems: limited validity?

01/02/2019

Organ-on-a-chip systems are technically a great enhancement of medical research because they facilitate testing of active ingredients on cell cultures in the chambers of a plastic chip. This replaces animal testing and improves patient safety. That being said, they are not a true-to-life replication of the human body and can only simulate a few functions and activities.
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