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Image: gene structure; Copyright: PantherMedia / krishna creations

Analyses of genome data enables tracking of avian influenza viruses

10/08/2020

An international consortium succeeded in tracking the genesis and spread of new reassortants of avian influenza viruses by the use of mathematical analyses. This large-scale international study has now been published in the scientific journal PNAS (Proceedings of the National Academy of Sciences of the United States of America).
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Image: woman in the laboratory; Copyright: RUB, Marquard

Sars-Cov-2: rapid test for the determination of antibodies

31/07/2020

To determine immunity to Sars-Cov-2 and the effectiveness of potential vaccines, the amount of neutralising antibodies in the blood of recovered or vaccinated individuals must be determined. A traditional neutralisation test usually takes two to three days and must be carried out with infectious coronaviruses in a laboratory complying to biosafety level 3.
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Image: graphic of cell membrane on a chip; Copyright: Susan Daniel/Cornell University

Cell membrane on a chip to speed up screening of drug candidates for COVID-19

06/07/2020

Researchers have developed a human cell 'membrane on a chip' that allows continuous monitoring of how drugs and infectious agents interact with our cells, and may soon be used to test potential drug candidates for COVID-19.
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Image: graphic for heart cell observation; Copyright: Daria Sokol/MIPT Press Office

Gentle technique to study heart tissue functioning

03/07/2020

Biophysicists from the Moscow Institute of Physics and Technology and their colleagues have proposed a simple way to observe the heart tissue. Besides being relatively uncomplicated, the new method is cheaper and produces results that are more independent, compared with the analogues currently in use. The study came out in Annals of Biomedical Engineering.
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Image: Man working in a laboratory; Copyright: Cedars-Sinai

COVID-19: virus can infect heart cells in lab dish

03/07/2020

A new study shows that SARS-CoV-2, the virus that causes COVID-19, can infect heart cells in a lab dish, indicating it may be possible for heart cells in COVID-19 patients to be directly infected by the virus. The discovery, published today in the journal Cell Reports Medicine, was made using heart muscle cells that were produced by stem cell technology.
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Image: 'Mini-brain' bioengineered from human stem cells; Copyright: Center for Alternatives to Animal Testing (CAAT), Johns Hopkins Bloomberg School of Public Health

Organoids suggest COVID-19 virus can infect human brain cells

02/07/2020

A multidisciplinary team from two Johns Hopkins University institutions, including neurotoxicologists and virologists from the Bloomberg School of Public Health and infectious disease specialists from the school of medicine, has found that organoids known as "mini-brains" can be infected by the SARS-CoV-2 virus that causes COVID-19.
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Image: point-of-care diagnostic system; Copyright: NUS Institute for Health Innovation & Technology

Portable COVID-19 diagnostic system for rapid on-site testing

29/06/2020

COVID-19 screening can soon be conducted directly at various testing stations, and patients can get their test results in about an hour from the time they get a nasal swab. A team of researchers from the National University of Singapore (NUS) has developed a portable COVID-19 micro-PCR diagnostic system that enables rapid and accurate on-site screening of infectious diseases.
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Image: 3D-printed tissue; Copyright: University of Colorado Denver

3D-printable material that mimics biological tissues

12/06/2020

Biological tissues have evolved over millennia to be perfectly optimized for their specific functions. Take cartilage as an example. It's a compliant, elastic tissue that's soft enough to cushion joints, but strong enough to resist compression and withstand the substantial load bearing of our bodies: key for running, jumping, and our daily wear and tear.
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Image: Woman pointing at data on a monitor; Copyright: Nathan L. Galli, University of Utah

Pattern found in tumors predicts life expectancy

18/05/2020

For the past 70 years, the best indicator of life expectancy for a patient with glioblastoma (GBM) has simply been age at diagnosis. Now, an international team of scientists has experimentally validated a predictor that is not only more accurate but also more clinically relevant: a pattern of co-occurring changes in DNA abundance levels.
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Image: Tube being filled in a laboratory setting; Copyright: UEF/ Raija Törrönen

Boost cancer treatment with new LAT1 inhibitor

18/05/2020

Researchers at the University of Eastern Finland have developed a new and promising drug compound for the treatment of cancer that inhibits natural amino acids from entering cancer cells. Since amino acids are essential for the growth and division of cancer cells, the new LAT1 inhibitor makes it possible to inhibit their growth. The study was published in the journal Apoptosis.
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Image: Colorful cubes with heart symbols are floating over a smartphone; Copyright: panthermedia.net/thodonal

Cardiology: digital solutions support those coping with chronic illness

03/02/2020

According to the World Health Organization (WHO), cardiovascular diseases are the leading cause of death worldwide, taking an estimated 17.9 million lives each year. Acute events such as heart attacks and strokes stand out in this setting. Chronic heart diseases can also be a debilitating condition for many patients. If cardiology uses digital methods and tools, it can reach more affected people.
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Image: diagnostic test on a table; Copyright: beta web GmbH/Melanie Prüser

Single-use tests: sensitivity and easy use combined for diagnostics

12/12/2019

Diagnostic testing usually takes some time and a sterile environment to get the results. To cut down on the costs and effort spend on these tasks there are different diagnostic tests. One of them are single-use tests offered by SensDx S.A. The technology behind them not only makes the process faster and easier, but provides the opportunity to expand into home use in the future as well.
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Image: Wrist with smartwatch, which measures the pulse rate; Copyright: panthermedia.net / Lev Dolgachov

mHealth: Atrial fibrillation detection – App supports heart health

08/05/2019

Atrial fibrillation is the most common type of persistent cardiac arrhythmia (irregular heart rhythm). Researchers estimate that 1.8 million Germans are presently affected by this disease. The condition is difficult to diagnose, frequently goes undetected and may result in a stroke. A new smartwatch medical app is designed to help patients detect atrial fibrillation before it’s too late.
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Image: digital capture of an eye; Copyright: panthermedia.net / cosmin momir

A digital look inside the human eye – when algorithms diagnose Diabetes

02/01/2019

Diabetes mellitus or simply diabetes has become very common and is often described as a lifestyle disease. More and more people are suffering from this chronic metabolic disorder. Next to established diagnostic procedures, digital retinal screening has shown to be successful - a promising technique that will also play an important role in the diagnosis of other diseases in the future.
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Image: Radiology assistant presses a button at the front of a CT; Copyright: panthermedia.net/Arne Trautmann

Lung cancer: Screening with low-Dose CT scans

01/10/2018

Lung cancer is one of the most common and deadliest cancers. The symptoms tend to be non-specific, often causing its detection to be too late. Currently, there is no comprehensive screening. This could change with the use of low-dose CT scans. It should be noted that this is not just an issue of technical feasibility. A screening test must also make sense from a health policy perspective.
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Image: DermaFC developed by Magnosco; Copyright: Magnosco

A startup makes melanin glow: skin cancer diagnostics with Magnosco

09/04/2018

When a skin lesion is suspected to exhibit malignant changes, it is usually promptly removed. However, not all cases require an excision of the affected tissue. The startup company Magnosco has developed a procedure that uses a laser to support the diagnosis and early detection of malignant melanoma.
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