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Image: Two researchers working in a laboratory with bags of blood plasma; Copyright: Houston Methodist

Study takes us a step closer to a universal antibody test for COVID-19

18/09/2020

A new study released by Houston Methodist takes researchers a significant step closer to developing a uniform, universal COVID-19 antibody test. The multicenter collaboration tested alternative ways to measure COVID-19 antibody levels that is faster and easier.
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Image: antibody testing platform; Copyright: OIST

Low-cost chip for detecting COVID-19 antibodies

11/09/2020

Robust and widespread antibody testing has emerged as a key strategy in the fight against SARS-CoV-2, the virus responsible for the COVID-19 pandemic. However current testing methods are too inaccurate or too expensive to be feasible on a global scale. But now, scientists at the OIST have developed a rapid, reliable and low-cost antibody test.
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Image: three male researchers in the laboratory; Copyright: Siwen Long

Nanobody may prevent COVID-19 infection

09/09/2020

Researchers at Karolinska Institutet in Sweden have identified a small neutralizing antibody, a so-called nanobody, that has the capacity to block SARS-CoV-2 from entering human cells. The researchers believe this nanobody has the potential to be developed as an antiviral treatment against COVID-19. The results are published in the journal Nature Communications.
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Image: samples in a laboratory setting; Copyright: Amy Drexelius

Detecting small amounts of virus in early infections

02/09/2020

Diagnostic devices that are used at home or in doctors' offices are often not sensitive enough to detect small amounts of a virus that might be present in samples from asymptomatic patients, which can occur in early stage COVID-19.
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Image: Microscopy image of mouse neurons; Copyright: MPI f. Biology of Ageing/ E. Motori

Nerve cells with energy saving program

01/09/2020

Mitochondria are the power plants of our cells and play an important role in providing energy for normal function of the tissues in our body. Nerve cells are particularly dependent on mitochondria for their activity and decreased mitochondrial function is seen in both inherited and more common age-associated forms of degenerative diseases.
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Image: depiction of a cerebral organoid; Copyright: Madeline Lancaster/IMBA

Project "HCA|Organoid": toward a single-cell atlas of human organoids

31/08/2020

HCA|Organoid is a new EU research project that combines single-cell profiling and organoid technology to validate organoids as faithful models of human biology. By creating well-characterized in vitro models of human organs, this resource will enable future discovery-driven and translational research on rare genetic diseases, complex multifactorial diseases, and on cancer.
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Image: Two woman sitting down and talking; Copyright: ATS

COVID-19: asthma may not be a significant risk factor

31/08/2020

A new research letter published online in the Annals of the American Thoracic Society examines whether asthma is a significant risk factor for developing COVID-19 that is severe enough to warrant hospitalization and intubation. According to the Centers for Disease Control and Prevention, individuals with asthma are at higher risk for hospitalization and other severe effects from COVID-19.
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Image: premature baby in an incubator; Copyright: Sharon McCutcheon/Unsplash

Machine learning tool predicts intestinal disease in premature infants

11/08/2020

Researchers from Columbia Engineering and the University of Pittsburgh have developed a sensitive and specific early warning system for predicting NEC in premature infants before the disease occurs. The prototype predicts NEC accurately and early, using stool microbiome features combined with clinical and demographic information.
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Image: muscles in a human arm; Copyright: PantherMedia / Sebastian Kaulitzki

Characterizing regulators of tissue inflammation

11/08/2020

Although macrophages are classified as immune cells functioning in the activation and resolution of tissue inflammation, it is now clear that they are critically involved in a variety of disease processes, such as chronic inflammatory diseases, tumor growth and metastasis and tissue fibrosis.
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Image: gene structure; Copyright: PantherMedia / krishna creations

Analyses of genome data enables tracking of avian influenza viruses

10/08/2020

An international consortium succeeded in tracking the genesis and spread of new reassortants of avian influenza viruses by the use of mathematical analyses. This large-scale international study has now been published in the scientific journal PNAS (Proceedings of the National Academy of Sciences of the United States of America).
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Image: A child in the ICU next to a ventilator; Copyright: PantherMedia/beerkoff1

Lab profiles differentiate MIS-C from COVID-19 in children

06/08/2020

Findings show that MIS-C is a post-infectious syndrome distinct from Kawasaki disease and may help guide treatment decisions.
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Image: woman in the laboratory; Copyright: RUB, Marquard

Sars-Cov-2: rapid test for the determination of antibodies

31/07/2020

To determine immunity to Sars-Cov-2 and the effectiveness of potential vaccines, the amount of neutralising antibodies in the blood of recovered or vaccinated individuals must be determined. A traditional neutralisation test usually takes two to three days and must be carried out with infectious coronaviruses in a laboratory complying to biosafety level 3.
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Image: laboratoy testing of biomarkers; Copyright: PantherMedia / sven hoppe

Revealing lung disease with exhaled biomarkers

21/07/2020

Using specialized nanoparticles, MIT engineers have developed a way to monitor pneumonia or other lung diseases by analyzing the breath exhaled by the patient. In a study of mice, the researchers showed that they could use this system to monitor bacterial pneumonia, as well as a genetic disorder of the lungs called alpha-1 antitrypsin deficiency.
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Image: Images of macrophages; Copyright: Hala Al Khoury / Uni Halle

Special coatings to reduce complications after implant surgery

01/07/2020

New coatings on implants could help make them more compatible. Researchers at the Martin Luther University Halle-Wittenberg (MLU) have developed a new method of applying anti-inflammatory substances to implants in order to inhibit undesirable inflammatory reactions in the body. Their study was recently published in the International Journal of Molecular Sciences.
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Image: point-of-care diagnostic system; Copyright: NUS Institute for Health Innovation & Technology

Portable COVID-19 diagnostic system for rapid on-site testing

29/06/2020

COVID-19 screening can soon be conducted directly at various testing stations, and patients can get their test results in about an hour from the time they get a nasal swab. A team of researchers from the National University of Singapore (NUS) has developed a portable COVID-19 micro-PCR diagnostic system that enables rapid and accurate on-site screening of infectious diseases.
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Image: UV Visual Lift; Copyright: by UVentions

Hygiene: Smart protection against pathogens like the coronavirus

23/03/2020

Germs such as bacteria, viruses or pathogenic fungi can spread from one person to another through direct contact when we shake hands or touch objects. People touch door handles and push elevator buttons in public places and constantly move in and out of spaces. Regular manual high-level disinfection is practically impossible. UVentions GmbH has found an intelligent solution for this problem.
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Image: A half-transparent red piece of tissue in a glass filled with a yellow fluid; Copyright: United Therapeutics

rhCollagen: genetically engineered building block for regenerative medicine

03/02/2020

Collagen is the stuff that holds our bodies together and that houses our cells. In regenerative medicine, it is also the stuff that can be applied to wounds to support healing. However, collagen from animal or human sources has some drawbacks for today’s medicine. This is where rhCollagen from the Israeli company CollPlant comes into play.
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Image: Athlete with knee pain; Copyright: panthermedia.net/Wavebreakmedia Itd

Endoprotheses: between possibility and reality

01/01/2020

When natural joints lose their ability to function, they can be completely or partially replaced by artificial joints, also called endoprotheses. Endoprotheses must be of a certain quality, as they should remain in the body as long as possible. In addition to some risks, endoprotheses can also contribute to a mobile and carefree life for young and old.
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Image: cemented artificial hip endoprostheses; Copyright: panthermedia.net/coddie

Endoprotheses: regaining independence and mobility

01/01/2020

Joints can suddenly or gradually deteriorate and lose their natural strength, whether it’s due to accidents, diseases or simple wear and tear. In some of these cases, implants of artificial joints – endoprostheses - can help. As a joint replacement, they are designed to stay in the body for as long as needed and as such improve the patient’s quality of life and mobility.
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Image: doctor consoles patients before surgery; Copyright: panthermedia.net/luckybusiness

Endoprosthetic surgery: modern and traditional approaches

01/01/2020

Surgery is required if you need an artificial joint. Patients and doctors must select the type of surgery that’s best suited and choose between robot-assisted, traditional or minimally invasive surgical approaches. Post-operative risks should be kept to a minimum, while benefits should outweigh any possible complications.
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Image: Flags are blowing in the wind to the backdrop of a dark evening sky; Copyright: Messe Düsseldorf/ctillmann

Medicine at the pulse of time: Innovations and trends at MEDICA 2019

04/11/2019

Soon, the world's largest trade fair for medical technology will open its doors again: More than 5.000 exhibitors will present their newest products and ideas at MEDICA from 18 to 21 November. You will not only meet well-known companies here, but also lots of young start-ups. Or, you can visit the MEDICA forums and conferences to experience a rich program of lectures and discussions.
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Image: Volker Bruns; Copyright: Fraunhofer ISS

AI software: "iSTIX opens your world to the possibilities of digital pathology"

08/10/2019

The healthcare market offers a multitude of microscopes that make cells visible to the human eye. The same applies to AI-based software for image analysis. After taking the microscopic images, scientist are faced with large volumes of scans with usually low resolution. Yet when all aspects merge together, they open up a the world of digital pathology.
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Image: Two petri dishes with different kinds of agar plates on which bacterial cultures are growing; Copyright: panthermedia.net/photographee.eu

Antibiotic resistance: technical tricks against pathogens

01/08/2019

An untreatable infection is a nightmare for physicians and potentially life-threatening to the patient. Unfortunately, more and more pathogens emerge that are resistant to drugs, especially antibiotics. We need to use our drugs smartly and come up with technical solutions as well to prevent our weapons from blunting in the future.
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Image: Sports shoes of an athlete; Copyright: panthermedia.net/ Daxiao_Productions

Sports medicine - performance values in best health

01/07/2019

Those who integrate physical activities into their own lifestyle live healthier and more balanced. But where are the physical limits? Can health status measurements also be carried out on the road? Discover more about how sports medical examinations contribute to maintain performance and minimize health risks in our Topic of the Month.
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Image: Marathon runner; Copyright: panthermedia.net/adamgregor

Sports medicine – keep moving to stay healthy

01/07/2019

Physical activity plays a big role in today's society. Whether you are an amateur or professional athlete – incorporating exercise into your life positively impacts your mental and physical health. Ideally, sport should be fun, pressure-free and not overburden you. But can you measure individual performance and align it with sports?
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Image: Three men in suits and a woman in a laboratory coat are standing in a laboratory; Copyright: Ministry of Economy of Mecklenburg-Hither Pomerania/Norbert Fellechner

On the trail of cancer: personalized cancer vaccine

01/03/2018

Conventional cancer treatment selection typically depends on the location of the tumor. However, this approach ignores the distinct gene mutations in the tumor of the individual patient. New cancer research approaches increasingly emphasize the concept of personalized therapy.
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