News from the Editors -- MEDICA - World Forum for Medicine

MEDICA Newsletter

Social Media

Image: model image of pathogens; Copyright: Sebastian Geibel

Pathogens: new insights in tuberculosis

10.10.2019

Researchers at the University of Würzburg and the Spanish Cancer Research Centre have gained new insights into the pathogen that causes tuberculosis. The work published in Nature provides the basis for a new approach in antibiotic therapy.
Read more
Image: blood vessel; Copyright: panthermedia.net/thelightwriter

Blood vessels: overly permeable

09.10.2019

In Germany alone there are around 400,000 patients who suffer from chronic inflammatory bowel diseases. For the first time, researchers have discovered that dysfunctions in blood vessels play a significant role in the development of such diseases. In experimental model systems, the progression of the disease slowed down significantly by eliminating these dysfunctions.
Read more
Image: Volker Bruns; Copyright: Fraunhofer ISS

AI software: "iSTIX opens your world to the possibilities of digital pathology"

08.10.2019

The healthcare market offers a multitude of microscopes that make cells visible to the human eye. The same applies to AI-based software for image analysis. After taking the microscopic images, scientist are faced with large volumes of scans with usually low resolution. Yet when all aspects merge together, they open up a the world of digital pathology.
Read more
Image: immunofluorescence of spleen sections of a mice; Copyright: IMP

Pathogens: a mechanism to control autoimmunity

08.10.2019

The immune system relies on B cells and their ability to make antibodies against an extremely broad range of pathogens. This broad responsiveness bears some risk, as B cells can also turn against healthy tissue - a phenomenon called autoimmunity.
Read more
Image: cells devouring tumor cells under a microscope; Copyright: Dr Fotini Vogiatzi

Immunotherapy: a promising antibody

07.10.2019

Acute lymphoblastic leukaemia (ALL) is the most common cancer in children. This form of blood cancer is caused by malignant abnormal precursor cells of certain white blood cells, and usually leads to a rapidly progressive reduction of bone marrow function, and thus impaired blood formation.
Read more
Image: Close up of synthetic multiepitope display scaffold; Copyright: University of Bristol

Vaccination: new synthetic vaccines to combat epidemics

26.09.2019

Infectious diseases continue to plague populations worldwide. Among the means at our disposal to counter this threat, vaccination has proven to be exceptionally powerful. A new type of vaccine that can be stored at warmer temperatures, removing the need for refrigeration, has been developed for mosquito-borne virus Chikungunya in a major advance in vaccine technology.
Read more
Image: bacterial syringe structure on a black background; Copyright: Shikuma Lab

Bacteriology: structures can be tapped to deliver drugs

19.09.2019

Not all bacteria spread diseases, many are beneficial and this strain has nanoscale syringes that deliver proteins which cause metamorphosis in marine animals, and could be modified as a novel drug delivery tool for future vaccines and cancer care.
Read more
Image: dna strings in yellow, blue and red; Copyright: panthermedia.net/khenghotoh

DNA: construction kit replaces expensive antibody medication

11.09.2019

Researchers at KU Leuven in Belgium have developed a technique to make sheep produce new antibodies simply by injecting the DNA building blocks. This approach is much cheaper and more efficient than producing antibodies industrially and administering them afterwards. The study in animals with a similar size as humans brings us a step closer to the clinical use of antibody gene therapy.
Read more
 Image: reasearcher in laboratory; Copyright: panthermedia.net/kasto

Islet-on-a-chip: miniature device for diabetes research

30.08.2019

In a study led by Harvard University's Kevin Kit Parker, microfluidics and human, insulin-producing beta cells have been integrated in an "Islet-on-a-Chip". The new device makes it easier for scientists to screen insulin-producing cells before transplanting them into a patient, test insulin-stimulating compounds, and study the fundamental biology of diabetes.
Read more
Image: new microneedle patch; Copyright: Celestine Hong and Yanpu He

Skin substitute: medication delivery in one minute

29.08.2019

Nearly 100,000 new cases of melanoma are diagnosed every year, according to the American Academy of Dermatology. Now, researchers have developed a fast-acting skin patch that efficiently delivers medication to attack melanoma cells. The device, tested in mice and human skin samples, is an advance toward developing a vaccine to treat melanoma and has widespread applications for other vaccines.
Read more
Image: DNA strand; Copyright: panthermedia.net/everythingposs

Analyzing systems: technique stores cellular 'memory' in DNA

29.08.2019

Engineers program human and bacterial cells to keep a record of complex molecular events. Using a technique that can precisely edit DNA bases, MIT researchers have created a way to store complex "memories" in the DNA of living cells, including human cells.
Read more
Image: A woman using an inhaler; Copyright: panthermedia.net/Andriy Popov

New biomarker may uncover uncontrolled asthma

22.08.2019

Cytokines are a type of proteins that are important to the signaling between cells in the body’s immune system, for example in the case of an infection or injury. A new study which is being published in the Journal of Allergy and Clinical Immunology is now indicating that the cytokine interleukin(IL)-26 could be used as a biological marker (biomarker) for uncontrolled asthma.
Read more
Image: Woman wearing a blue shirt uses smart textiles; Copyright: Ramses Martinez/Purdue University

Wearables: turning away bacteria with your clothes

08.08.2019

New rainproof, stainproof technology turns clothing into self-powered remotes. A new addition to your wardrobe may soon help you turn on the lights and music - while also keeping you fresh, dry, fashionable, clean and safe from the latest virus that's going around.
Read more
Image: Multi-Electrode Layout for Parallel Analysis of Multiple Cell Samples in Microfluic-Chips.; Copyright: Fraunhofer EMFT, Bernd Müller

Cell observation: new approach in the fight against viruses

06.08.2019

In the ViroSens project, researchers from the Fraunhofer-Gesellschaft in Sulzbach and Regensburg are working together with industrial partners on a novel analytical method to make the potency testing of vaccines more efficient and cost-effective.
Read more
Image: Two petri dishes with different kinds of agar plates on which bacterial cultures are growing; Copyright: panthermedia.net/photographee.eu

Antibiotic resistance: technical tricks against pathogens

01.08.2019

An untreatable infection is a nightmare for physicians and potentially life-threatening to the patient. Unfortunately, more and more pathogens emerge that are resistant to drugs, especially antibiotics. We need to use our drugs smartly and come up with technical solutions as well to prevent our weapons from blunting in the future.
Read more
Image: Bacteria in the gut are pulled into the helical channels by an osmotic 'pump' in the pill.; Copyright: Nano Lab, Tufts University

Diagnostics: 3D-printed pill samples aid diagnosis and treatment

29.07.2019

The pill is the first known working device capable of non-invasively and accurately assessing the profile of bacterial species inhabiting any stage of the gastrointestinal tract. The ability to profile bacterial species inhabiting the gut could have important implications for conditions that affect and are affected by the intestinal microbiome.
Read more
Image: blood test; Copyright: panthermedia.net/belchonock

Blood test: may also identify people at most TB risk

23.07.2019

A new study conducted by researchers in Leicester and Nottingham has shown the potential for a new blood test to not only diagnose human tuberculosis (TB) but also identify those at most risk of developing the disease.
Read more
Image: doctor with pills in hands; Copyright: panthermedia.net/leolintang

Two new algorithms identify patients at risk of HIV

22.07.2019

Two new studies developed algorithms that can identify patients who are at risk of acquiring HIV and may benefit from preventive care.
Read more
Image: Sports shoes of an athlete; Copyright: panthermedia.net/ Daxiao_Productions

Sports medicine - performance values in best health

01.07.2019

Those who integrate physical activities into their own lifestyle live healthier and more balanced. But where are the physical limits? Can health status measurements also be carried out on the road? Discover more about how sports medical examinations contribute to maintain performance and minimize health risks in our Topic of the Month.
Read more
Image: Marathon runner; Copyright: panthermedia.net/adamgregor

Sports medicine – keep moving to stay healthy

01.07.2019

Physical activity plays a big role in today's society. Whether you are an amateur or professional athlete – incorporating exercise into your life positively impacts your mental and physical health. Ideally, sport should be fun, pressure-free and not overburden you. But can you measure individual performance and align it with sports?
Read more
Image: Three men in suits and a woman in a laboratory coat are standing in a laboratory; Copyright: Ministry of Economy of Mecklenburg-Hither Pomerania/Norbert Fellechner

On the trail of cancer: personalized cancer vaccine

01.03.2018

Conventional cancer treatment selection typically depends on the location of the tumor. However, this approach ignores the distinct gene mutations in the tumor of the individual patient. New cancer research approaches increasingly emphasize the concept of personalized therapy.
Read more
Image: Collage of several MRI images of the heart, in which different locations are marked with red arrows; Copyright: University Hospital Münster/Ali Yilmaz

Myocarditis: more specific diagnosis thanks to molecular imaging

01.09.2017

There are many causes of myocarditis or inflammation of the heart muscle. Oftentimes, the culprits are viruses or bacteria and sometimes even an acute heart attack. Regardless of the cause, it creates a challenge for cardiologists: a diagnosis tends to be only nonspecific without a biopsy. A cardiac MRI and molecular imaging promise to provide assistance.
Read more
Image: A petri dish with yellow bacterial cultures on a black ground; Copyright: panthermedia.net/kwanchaichaiudom

Laboratory medicine: confronting infections with speed and foresight

03.04.2017

The laboratory is one of the most important and pivotal bastions in patient care. In the laboratory, acute, chronic and genetic diseases are diagnosed, the progression of diseases such as diabetes is regularly checked or specialists look for biomarkers to adapt cancer therapies.
Read more