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Image: vascular prosthesis for the aorta; Copyright: JOTEC GmbH

Prosthesis: new lease of life thanks to new aorta

20.09.2019

Patients with the rare Loeys-Dietz syndrome suffer from aortic enlargement which may result in sudden over-expansion and a fatal aortic tear. In order to prevent this from happening, an aortic prosthesis must be implanted.
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 Image: Research team of nonoparticle sensor; Copyright: Asociación RUVID

Optical sensor: detects very low glucose concentrations

17.09.2019

The Optical Research Group of the Universitat Jaume I has developed an optical nanoparticle sensor capable of detecting very low glucose concentrations, such as those present in a person's tear, by means of fluorescent carbon quantum dots, applying synthesis of nanomaterials based on irradiation with ultra-short lasers, which is an alternative, sustainable and non-polluting method.
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Image: purple microscope image of squamous cell carcinoma of the lung and squamous cell carcinoma of the head and neck; Copyright: Jurmeister/Charité

Machine Learning: improving the diagnosis of head and neck cancers

16.09.2019

Researchers from Charité - Universitätsmedizin Berlin and the German Cancer Consortium have successfully solved a longstanding problem in the diagnosis of head and neck cancers. Working alongside colleagues from TU Berlin, the researchers used artificial intelligence to develop a new classification method which identifies the primary origins of cancerous tissue based on chemical DNA changes.
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Image: dna strings in yellow, blue and red; Copyright: panthermedia.net/khenghotoh

DNA: construction kit replaces expensive antibody medication

11.09.2019

Researchers at KU Leuven in Belgium have developed a technique to make sheep produce new antibodies simply by injecting the DNA building blocks. This approach is much cheaper and more efficient than producing antibodies industrially and administering them afterwards. The study in animals with a similar size as humans brings us a step closer to the clinical use of antibody gene therapy.
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Image: a stent coated with titanium oxynitride; Copyright: Fraunhofer IKTS

Stents: better protection against occluded blood vessels

06.09.2019

Cardiovascular stents are special implants used to widen blood vessels that have become constricted as a result of calcium deposits. In some cases, the body's immune system can reject these implants in a process known as foreign-body reaction. In a joint project with partners, Fraunhofer researchers have now developed enhanced coatings that substantially improve the biocompatibility of stents.
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 Image: reasearcher in laboratory; Copyright: panthermedia.net/kasto

Islet-on-a-chip: miniature device for diabetes research

30.08.2019

In a study led by Harvard University's Kevin Kit Parker, microfluidics and human, insulin-producing beta cells have been integrated in an "Islet-on-a-Chip". The new device makes it easier for scientists to screen insulin-producing cells before transplanting them into a patient, test insulin-stimulating compounds, and study the fundamental biology of diabetes.
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Image: wearable placed on the forehead of a man; Copyright: Bizen Maskey, Sunchon National University

Wearables: sensors detect what's in your sweat

21.08.2019

New easy-to-make sensors can provide real-time measurements of sweat rate and electrolytes and metabolites in perspiration. Needle pricks not your thing? A team of scientists at the University of California, Berkeley, is developing wearable skin sensors that can detect what's in your sweat.
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Image: blood samples; Copyright: Max Planck Institute for Biology of Ageing

Biomarker: health indication in old age

21.08.2019

Researchers on ageing from the Max Planck Institute for Biology of Ageing and the Leiden University Medical Center (LUMC) collaborate to link basic insights from model organisms to the causes of ageing in humans. They can determine the disease vulnerability of older people using a defined set of substances in the blood.
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Image: nanoparticles in a close-up; Copyright: panthermedia.net/raimund14

Precision medicine: graphene nanoflakes as a new tool

20.08.2019

Chemists funded by the SNSF have created a new compound for flexible drug delivery that specifically targets prostate cancer cells. Incorporating four different molecules, the compound prevents tumour cells from multiplying, can be detected by medical imaging and has staying power in the bloodstream.
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Image: woman in a lab coat and disposable gloves choosing a sample from the brain bank; Copyright: UC Davis Health

AI: mapping the brain landscape for Alzheimer's disease

16.08.2019

A team of researchers lead by Brittany Dugger of UC Davis Health has been awarded a $3.8 million grant from the National Institute for Aging (NIA) to help define the neuropathology of Alzheimer's disease in Hispanic cohorts.
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Image: man - Muhammed Murtaza - in the laboratory; Copyright: Courtesy of TGen

Blood test: liquid biopsy improves breast cancer diagnostics

14.08.2019

A new type of blood test for breast cancer could help avoid thousands of unnecessary surgeries and otherwise precisely monitor disease progression, according to a study led by the Translational Genomics Research Institute (TGen) and Mayo Clinic in Arizona.
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Image: blood samples on a sheet of paper; Copyright: panthermedia.net/belchonock

mHealth: blood pressure monitoring like taking a video selfie

07.08.2019

Blood pressure monitoring might one day become as easy as taking a video selfie, according to new research in Circulation: Cardiovascular Imaging, an American Heart Association journal. Transdermal optical imaging measures blood pressure by detecting blood flow changes in smartphone-captured facial videos.
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Image: Multi-Electrode Layout for Parallel Analysis of Multiple Cell Samples in Microfluic-Chips.; Copyright: Fraunhofer EMFT, Bernd Müller

Cell observation: new approach in the fight against viruses

06.08.2019

In the ViroSens project, researchers from the Fraunhofer-Gesellschaft in Sulzbach and Regensburg are working together with industrial partners on a novel analytical method to make the potency testing of vaccines more efficient and cost-effective.
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Image: Man who had a stroke might be treated with thrombectomy; Copyright: panthermedia.net/olegdudko

Thrombectomy: potential treatment for larger strokes

31.07.2019

Building on research results published today in JAMA Neurology showing patients with larger ischemic strokes could benefit from endovascular thrombectomy, an international, multicenter Phase III clinical trial will be starting at The University of Texas Health Science Center at Houston (UTHealth).
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Image: blood test; Copyright: panthermedia.net/belchonock

Blood test: may also identify people at most TB risk

23.07.2019

A new study conducted by researchers in Leicester and Nottingham has shown the potential for a new blood test to not only diagnose human tuberculosis (TB) but also identify those at most risk of developing the disease.
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Image: Two men in the zoo holding turtles in their hands; Copyright: Oliver Dietze

Diagnostics: Animal blood samples help predict human diseases

17.07.2019

Penguins, Asian elephants and many other animal species live in the zoos of Saarbrücken and Neunkirchen. As they come from different continents, blood is regularly taken from the animals to check their health.
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Image: fingers with disposable gloves holding a blood sample; Copyright: panthermedia.net/alexraths

Diagnostics: new blood test for detecting Alzheimer's disease

10.07.2019

Researchers from Lund University have used a method to develop a new blood marker capable of detecting whether or not a person has Alzheimer’s disease. If the method is approved for clinical use, the researchers hope eventually to see it used as a diagnostic tool in primary healthcare. This autumn, they will start a trial in primary healthcare to test the technique.
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Image: elderly man in the lab injecting a liquid into a chip; Copyright: panthermedia.net/matej kastelic

Human-on-a-chip: prediction of in vivo results based on in vitro model

08.07.2019

Hesperos Inc., pioneers of the human-on-a-chip in vitro system has announced the use of its innovative multi-organ model to successfully measure the concentration and metabolism of two known cardiotoxic small molecules over time, to accurately describe the drug behavior and toxic effects in vivo. The findings support the potential of body-on-a-chip systems to transform the drug discovery process.
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Image: Sports shoes of an athlete; Copyright: panthermedia.net/ Daxiao_Productions

Sports medicine - performance values in best health

01.07.2019

Those who integrate physical activities into their own lifestyle live healthier and more balanced. But where are the physical limits? Can health status measurements also be carried out on the road? Discover more about how sports medical examinations contribute to maintain performance and minimize health risks in our Topic of the Month.
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Image: Marathon runner; Copyright: panthermedia.net/adamgregor

Sports medicine – keep moving to stay healthy

01.07.2019

Physical activity plays a big role in today's society. Whether you are an amateur or professional athlete – incorporating exercise into your life positively impacts your mental and physical health. Ideally, sport should be fun, pressure-free and not overburden you. But can you measure individual performance and align it with sports?
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Image: The BlooDe device; Copyright: Université de Franche-Comté

Haematology: problems of anti-bleeding detected in 60 mins

01.07.2019

Researchers from the Universities of Geneva and Franche-Comté have developed an innovative device that investigates a patient's platelet capacity in near real-life conditions so that bleeding can be stopped (haemostasis).
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Image: CT scan open; Copyright: panthermedia.net/SimpleFoto

Functional imaging: a look at the command center

01.04.2019

All information from our body and the environment converges in our brain and is transformed into reactions in milliseconds. It is essential for medicine and research to know what our switching centre looks like. Functional methods are used to observe it more closely during work.
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Image: Patient during an fMRI examination; Copyright: panthermedia.net/Chris De Silver

Functional imaging: what makes the brain tick?

01.04.2019

Our brain is the command center of our body. This is where all information and impressions are collected and converted into responses and movements. Modern imaging techniques offer physicians and researchers unique insights into the actions of the human central nervous system. The functional imaging technique allows them to watch our brain in action.
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Image: Ellipsoid of revolution with a gold coating to detect backscattered photons from the skin tissue; Copyright: Sven Delbeck/Fachhochschule Südwestfalen

Blood Sugar Monitoring: Using Infrared Instead of Invasive Techniques

22.03.2019

Over six million people in Germany have diabetes. It is estimated that almost 400 million people are affected by this disease worldwide. Diabetes sufferers must prick their fingers several times a day to monitor their blood sugar.
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Photo: Preview picture of video

From algorithm to rapid test – Artificial Intelligence classifies blood cells

21.11.2018

Our blood reveals a lot about our physical health. The shape of our blood cells sheds light on several hereditary diseases for example. For a diagnosis, the cells must first be examined under the microscope and categorized into a specific cell class. We met with Dr. Stephan Quint and Alexander Kihm of the Institute of Physics at the Saarland University, who explained how this classification works.
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Image: several leg pairs during a run; Copyright: panthermedia.net/lzf

Diagnostics at record speeds – POCT in high-performance sports

02.11.2018

This is what diagnostic investigation normally looks like: a patient sample is collected, sent to the laboratory and analyzed. Once that's completed, the patient is told of the lab test result. But if the patient is a high-performance athlete and has to follow and stick to a rigid training schedule, he or she needs these results immediately. What makes this possible? Point-of-care testing!
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Image: AcCellerator research device at an exhibition stand; Copyright: Daniel Klaue, ZELLMECHANIK DRESDEN GmbH

Cells in the speed trap – diagnosis in a matter of seconds

22.06.2018

A drop of blood provides a lot of valuable information. However, it takes several hours to analyze the blood of a patient and make a diagnosis. This takes away a lot of time that's crucial for treatment. A new method intends to considerably speed up this process by testing the cells in the blood in terms of their deformability and immune response.
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Image: Woman holding a doll in a glowing pyjamas; Copyright: Empa

Illuminated pyjamas treat jaundice in mommy's arms

20.12.2017

Sixty percent of newborns are affected by jaundice during their first days of life. In most cases, the condition is harmless. The ailment is more pronounced in premature babies, whose treatment involves irradiation with blue light in a special incubator – naked and alone.
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Image: POCT-device and patient files; Copyright: panthermedia.net/gabriella

Point-of-care testing: helpful when things need to happen quickly?

01.08.2017

Advances in technology and analysis techniques, as well as the increasing miniaturization of laboratory equipment and processes, make it possible: patient-side laboratory testing, better known as point-of-care testing or POCT. There are many POCT projects and all of them promise a rapid diagnosis as well as economic advantages. But are these tests also suited for everyday medical testing?
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Image: blood is taken from a finger and analysed by a blood testing device; Copyright:hes_so_valais_wallis

Without any delay: drug dose adjustment at the point of care

01.08.2017

Many therapeutic drugs are very powerful, but they are also very toxic at the same time. Thus, they have to be measured regularly, again and again, so that an adjustment of the individual drug dosage can be made. Until now, the "normal" way was to take the blood sample, send it to a central laboratory and get the results after some days. A new point-of-care test can measure it in 15 minutes.
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Image: Collage made of two images, one show a round, transparent plastic disc with micro channels, one shows a plastic chip; Copyright: Hahn-Schickard, Image Bernd Müller

Prenatal diagnosis: genetic analysis using droplet PCR

24.07.2017

A new analysis method that uses fetal DNA extracted from the mother’s blood is designed to non-invasively reach a prenatal diagnosis of genetic disorders in a child. A task force of the Hahn Schickard Society for Applied Research is an active part of the "ANGELab" project and co-developed this diagnostic procedure.
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