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Image: Man with mouthguard and laboratory glasses holding Petri dish up; Copyright: panthermedia.net/kasto

Cardiac Tissue Engineering: a heart out of the Petri dish

23.09.2019

For patients waiting for donor organs, every day can mean the difference between life and death. Making things even more complicated is the fact that not every organ is a compatible match with the patient. It would mean enormous progress if we could grow organs from the patient's own cells in the lab. That's why patients with heart disease place big hope in tissue engineering.
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 Image: reasearcher in laboratory; Copyright: panthermedia.net/kasto

Islet-on-a-chip: miniature device for diabetes research

30.08.2019

In a study led by Harvard University's Kevin Kit Parker, microfluidics and human, insulin-producing beta cells have been integrated in an "Islet-on-a-Chip". The new device makes it easier for scientists to screen insulin-producing cells before transplanting them into a patient, test insulin-stimulating compounds, and study the fundamental biology of diabetes.
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Image:  bone tissue replicated with 3D technology; Copyright: panthermedia.net/eranicle

Regenerative medicine: 'Bone in a dish'

07.08.2019

Like real bone, the material developed at Oregon Health & Science University has a 3D mineral structure populated with living cells, providing a unique model to study bone function, diseases, regeneration.
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Image: Mouse cochlea with hair cells shown in green and auditory nerves shown in red.; Copyright: Doetzlhofer lab

Tissue engineering: restoring damaged cells in the ear

06.08.2019

Using genetic tools in mice, researchers at Johns Hopkins Medicine say they have identified a pair of proteins that precisely control when sound-detecting cells, known as hair cells, are born in the mammalian inner ear. The proteins, described in a report published June 12 in eLife, may hold a key to future therapies to restore hearing in people with irreversible deafness.
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Image: View over the shoulders of two doctors at a screen showing a model of a heart; Copyright: panthermedia.net/Wavebreakmedia ltd

Regenerative heart valves: from simulation to replacement

23.07.2018

Every year, more than 250,000 patients worldwide receive heart valve implants. Children require repeated replacement surgery because their bodies are still growing, the prosthetic heart valves are not. Regenerative heart valves solve this problem. Until now, we have only been able to monitor how these living implants develop in the body after the fact. Computer models now make this predictable.
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Image: two men in the laboratory next to the Organ Care System with a pig's lung inside; Copyright: Kaiser/MHH

Organ Care System: treatment under extreme conditions

08.05.2018

Multidrug-resistant organisms that are treated with a dosage that exceeds the regular dose a hundred times and at temperatures of over 40 degrees Celsius – the human organism is unable to handle it. Yet if the diseased organ is treated outside of the body, extreme conditions are an option. For the first time, physicians have succeeded in treating a severe case of pneumonia by using the OCS.
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"Spray-On" muscle fibers for biomimetic surfaces

08.01.2018

Few patients with heart failure are fortunate enough to receive a donor's heart. Ventricular assist devices (or heart pumps) have been around for several years and are designed to buy time as patients wait for a transplant. Unfortunately, the body doesn't always tolerate these devices.
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