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Image: illustration with colored circles to illustrate the immune system's defences; Copyright: Michele Kellett and James Anderson/University of Washington

Michele Kellett and James Anderson/University of Washington

Model finds COVID-19 deaths among elderly may be due to genetic limit on cell division

13/05/2022

Your immune system’s ability to combat COVID-19, like any infection, largely depends on its ability to replicate the immune cells effective at destroying the SARS-CoV-2 virus that causes the disease. These cloned immune cells cannot be infinitely created, and a key hypothesis of a new study is that the body’s ability to create these cloned cells falls off significantly in old age.
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Image: Female nurse looks at results on computer; Copyright: engagestock

engagestock

New computational tool to interpret clinical significance of cancer mutations

12/05/2022

The software, called CancerVar, standardizes procedures to help researchers assess the clinical impacts of over 13 million somatic cancer mutations.
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Image: Mikael Benson, professor at Linköping University ; Copyright: Thor Balkhed/Linköping University

Thor Balkhed/Linköping University

"Digital twins" aid to give individual patients the right treatment

11/05/2022

An international team of researchers have developed advanced computer models, or "digital twins", of diseases, with the goal of improving diagnosis and treatment.
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Image: Shaopeng Wang poses for the camera; Copyright: The Biodesign Institute at Arizona State University

The Biodesign Institute at Arizona State University

A sharper image for proteins

05/05/2022

To fully understand proteins and their myriad functions, researchers have developed sophisticated means to see and study them using advanced microscopy, enhanced light detection, imaging software and the integration of advanced hardware systems. A new study from Arizona State University describes a new technique that promises to revolutionize the imaging of proteins and other vital biomolecules.
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Image: Three men and one woman in an OR - Bernd Auber, Alexander von Gise, Michael Sasse, Bettina Bohnhorst; Copyright: Karin Kaiser/MHH

Karin Kaiser/MHH

Rare diseases: rapid diagnosis instead of a long odyssey

26/04/2022

Can the treatment of seriously ill children with rare diseases be improved by rapid genetic diagnosis? This question is being investigated by a team from Pediatrics and Human Genetics at Hannover Medical School (MHH) in the "Baby Lion" study. The focus is on decoding the genome, i.e. the entire genetic information of a human being, in just a few days.
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Image: View over the shoulder of a female laboratory technician who is filling a sample into a vial; Copyright: friends_stock

friends_stock

World Laboratory Day 2022: Celebrate your lab!

22/04/2022

Drugs, vaccines, pathogen vulnerabilities, information about genetics and genetic material - the cornerstones of modern medicine are laid in research laboratories. And without efficient laboratory diagnostics, we would not be able to detect and treat a wide range of diseases. Two reasons to celebrate laboratories and the people who work there.
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Image: The motherboard of a COVID-19 rapid testing device; Copyright: Photo courtesy of Houndstoothe Analytics.

Photo courtesy of Houndstoothe Analytics

Highly accurate, 30-second coronavirus test

15/04/2022

Researchers at the University of Florida, however, have helped developed a COVID-19 testing device that can detect coronavirus infection in as little as 30 seconds as sensitively and accurately as a PCR, or polymerase chain reaction test, the gold standard of testing.
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Image: Device for single particle combinatorial lipidic nanocontainer fusion dots; Copyright: Nikos Hatzakis, University of Copenhagen

Nikos Hatzakis, University of Copenhagen

Revolutionary tool will meet future pandemics with accelerated response

07/04/2022

A new tool speeds up development of vaccines and other pharmaceutical products by more than one million times while minimizing costs.
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Image: Scientist examining cells under a microscope; Copyright: PantherMedia / Anamaria Mejia

PantherMedia / Anamaria Mejia

Brain organoids provide insight into malformations of cortical development

23/03/2022

A study at the Hector Institute for Translational Brain Research (HITBR) at the Central Institute of Mental Health (CIMH) in Mannheim shows that cerebral organoids open up new insights into the development of the human brain and associated disorders.
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Image: Nurse Emily Wheeler poses for the camera. ; Copyright: Yasmine Phillips

Yasmine Phillips

New agreement uses 3D technology to help treat rare genetic disorder

21/03/2022

Researchers will use 3D facial analysis technology to help understand and eventually guide the treatment of a rare genetic disorder that affects one in 50,000 people as the result of a new agreement.
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Image: A young smiling male researcher in a lab - Dr. Kishore Kumar; Copyright: Garvan Institute of Medical Research

Garvan Institute of Medical Research

Single test for over 50 genetic diseases

08/03/2022

A new DNA test, developed by researchers at the Garvan Institute of Medical Research in Sydney and collaborators from Australia, UK and Israel, has been shown to identify a range of hard-to-diagnose neurological and neuromuscular genetic diseases quicker and more-accurately than existing tests.
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Image: A swab is lying across a sample vial; Copyright: PantherMedia/fotoquique

Point-of-care tests: rapid diagnosis in emergency situations

01/06/2021

In emergency medicine, a faster diagnosis leads to a faster treatment of the patient. Point-of-care test solutions can provide immediate on-site insights into the patient’s condition. COVID-19 adds another dimension: the devices can provide a level of security and safety – one that goes beyond intensive care.
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Image: A half-transparent red piece of tissue in a glass filled with a yellow fluid; Copyright: United Therapeutics

rhCollagen: genetically engineered building block for regenerative medicine

03/02/2020

Collagen is the stuff that holds our bodies together and that houses our cells. In regenerative medicine, it is also the stuff that can be applied to wounds to support healing. However, collagen from animal or human sources has some drawbacks for today’s medicine. This is where rhCollagen from the Israeli company CollPlant comes into play.
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Image: A lab technician is using a pipette to fill a solution into a petri dish; Copyright: panthermedia.net/Arne Trautmann

Last-resort antibiotics: "We can identify carbapenemases within half an hour"

01/08/2019

Antibiotic resistance is modern medicine's greatest challenge. Some bacteria only respond to a handful of antibiotics, prompting hospitals to spend a lot of time finding an effective drug. That’s why it is critical for physicians to rapidly identify antibiotic resistance to avoid ineffective treatments.
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