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Image:  bone tissue replicated with 3D technology; Copyright: panthermedia.net/eranicle

Regenerative medicine: 'Bone in a dish'

07.08.2019

Like real bone, the material developed at Oregon Health & Science University has a 3D mineral structure populated with living cells, providing a unique model to study bone function, diseases, regeneration.
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Image: Mouse cochlea with hair cells shown in green and auditory nerves shown in red.; Copyright: Doetzlhofer lab

Tissue engineering: restoring damaged cells in the ear

06.08.2019

Using genetic tools in mice, researchers at Johns Hopkins Medicine say they have identified a pair of proteins that precisely control when sound-detecting cells, known as hair cells, are born in the mammalian inner ear. The proteins, described in a report published June 12 in eLife, may hold a key to future therapies to restore hearing in people with irreversible deafness.
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Image: A researcher displays the pliability of a trileaf heart valve bioprinted in collagen.; Copyright: Carnegie Mellon University College of Engineering

Tissue engineering: 3D printing the human heart

05.08.2019

A team of researchers from Carnegie Mellon University has published a paper in Science that details a new technique allowing anyone to 3D bioprint tissue scaffolds out of collagen, the major structural protein in the human body. This first-of-its-kind method brings the field of tissue engineering one step closer to being able to 3D print a full-sized, adult human heart.
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Image: sensor; Copyright: Purdue University

Diagnostics: 3D mapping technology to monitor and track cells and tissues

11.07.2019

Medical advancements can come at a physical cost. Often following diagnosis and treatment for cancer and other diseases, patients' organs and cells can remain healed but damaged from the medical condition. In fact, one of the fastest growing medical markets is healing and/or replacing organs and cells already treated, yet remain damaged by cancer, cardiovascular disease and other medical issues.
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Image: Two physicians are talking to a wheelchair user; Copyright: Kessler Foundation

Orthopedics: Grant to treat shoulder injuries in wheelchair users

03.06.2019

The New Jersey Commission on Spinal Cord Research awarded a $549,000 grant to Trevor Dyson-Hudson, MD, of Kessler Foundation; the grant is one of three awarded to Foundation scientists for spinal cord injury research, totaling $1.74 million.
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Image: illustration of the production of tissues and organs with lithography; Copyright: F. Pampaloni, BRIGHTER, 2019

Tissue Engineering: producing tissue and organs through lithography

28.05.2019

The production of artificial organs is a hot research topic. In the near future, artificial organs will compensate for the lack of organ donations and replace animal experiments. Although there are already promising experiments with 3D printers that use a "bio-ink" containing living cells, a functional organ has never been created in this way.
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Image: View over the shoulders of two doctors at a screen showing a model of a heart; Copyright: panthermedia.net/Wavebreakmedia ltd

Regenerative heart valves: from simulation to replacement

23.07.2018

Every year, more than 250,000 patients worldwide receive heart valve implants. Children require repeated replacement surgery because their bodies are still growing, the prosthetic heart valves are not. Regenerative heart valves solve this problem. Until now, we have only been able to monitor how these living implants develop in the body after the fact. Computer models now make this predictable.
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Image: Two hands are holding a tubular frame that is carrying a glistening wet, white tube; Copyright: Leibniz University of Hanover/Institute of Technical Chemistry

Tissue engineering: how to grow a bypass

23.04.2018

A bypass is a complicated structure. It is either made of synthetic materials that can cause blood clots and infections or created by using the patient’s veins. However, the latter often does not yield adequate material. A newly developed bioreactor could solve this problem in the future. It is designed to tissue engineer vascular grafts by using the body’s own material.
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"Spray-On" muscle fibers for biomimetic surfaces

08.01.2018

Few patients with heart failure are fortunate enough to receive a donor's heart. Ventricular assist devices (or heart pumps) have been around for several years and are designed to buy time as patients wait for a transplant. Unfortunately, the body doesn't always tolerate these devices.
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