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Biosensor: technology created for stem cells
12.11.2019
A Rutgers-led team has created better biosensor technology that may help lead to safe stem cell therapies for treating Alzheimer's and Parkinson's diseases and other neurological disorders.
Genetic data: a method to standardize analysis
12.11.2019
MIPT researchers have collaborated with Atlas Biomedical Holding and developed a new bioinformatics data analysis method. The developed program, EphaGen, can be used for quality control when diagnosing genetic diseases. The team published the article in Nucleic Acid Research.
Immunology: why beta-blockers cause skin inflammation
08.11.2019
Beta-blockers are often used to treat high blood pressure and other cardiovascular diseases. However, in some patients they can trigger or exacerbate psoriasis, an inflammatory skin disease. Scientists at the University of Bonn and Freie Universität Berlin have now found a possible cause for this. Their results have been published in the renowned journal "Autophagy".
Regenerative medicine: material for cell immune response
04.11.2019
Scientists of Tomsk Polytechnic University jointly with the University of Montana (USA) proposed a new promising material for regenerative medicine for recovery of damaged tissues and blood vessels.
Cancer treatment: attacking with sound
30.10.2019
Drugs can be safely delivered to cancerous lymph nodes via the lymphatic system and then released inside the nodes using sound waves. Tohoku University researchers tested the treatment on mice with metastatic breast cancer and published their findings in the journal Scientific Reports.
Brain mapping: unraveling the dense networks
29.10.2019
The methods to analyze neuronal networks sparsely have been available for decades, the dense mapping of neuronal circuits is a major scientific challenge. Researchers from the MPI for Brain Research have now succeeded in the dense connectomic mapping of brain tissue from the cerebral cortex, and quantify the possible imprint of learning in the circuit.
3D-printing: finds cancer cells
29.10.2019
Finding a handful of cancer cells hiding among billions of blood cells in a patient sample can be like finding a needle in a haystack. In a new approach enabled by 3D-printed cell traps, researchers are removing the hay to expose the cancer cells.
Cells: toxin, trauma, therapy?
28.10.2019
The department of Prof. Tanja Weil at the Max Planck Institute for Polymer Research has, in cooperation with the group of Prof. Holger Barth from the Institute of Pharmacology and Toxicology at the Ulm University, shown in initial laboratory tests that they are able to specifically modulate processes in human white blood cells in vitro.
Cells: gut health influences brain health
25.10.2019
Over the last two decades, scientists have observed a clear link between autoimmune disorders and a variety of psychiatric conditions. For example, people with autoimmune disorders such as inflammatory bowel disease (IBD), psoriasis and multiple sclerosis may also have depleted gut microbiota and experience anxiety, depression and mood disorders.
Radiotherapy: breaking the stroma barrier
22.10.2019
Pancreatic cancer is one of the leading causes of cancer related deaths worldwide. Patients with pancreatic cancer often receive chemotherapy or radiation therapy, which are not always effective and can have toxic side effects. The method may offer an effective treatment for pancreatic cancer with fewer side effects in surrounding organs.
Bioprinting: living cells in a 3D printer
22.10.2019
Tissue growth and the behavior of cells can be controlled and investigated particularly well by embedding the cells in a delicate 3D framework. This is achieved using additive 3D printing methods - so called "bioprinting" techniques. However, some methods are very imprecise or only allow a very short time window in which the cells can be processed without being damaged.
Cells: potential liver cancer treatment
10.10.2019
Liver cancer is the second leading cause of cancer-related deaths worldwide. The most common primary liver cancer in adults is known as hepatocellular carcinoma (HCC), and accounts for approximately 780.000 deaths every year. Even with advanced surgical treatments or transplantation, the 5-year survival rate for HCC patients remains poor due to frequent recurrence.
Pathogens: new insights in tuberculosis
10.10.2019
Researchers at the University of Würzburg and the Spanish Cancer Research Centre have gained new insights into the pathogen that causes tuberculosis. The work published in Nature provides the basis for a new approach in antibiotic therapy.
Blood vessels: overly permeable
09.10.2019
In Germany alone there are around 400,000 patients who suffer from chronic inflammatory bowel diseases. For the first time, researchers have discovered that dysfunctions in blood vessels play a significant role in the development of such diseases. In experimental model systems, the progression of the disease slowed down significantly by eliminating these dysfunctions.
Pathogens: a mechanism to control autoimmunity
08.10.2019
The immune system relies on B cells and their ability to make antibodies against an extremely broad range of pathogens. This broad responsiveness bears some risk, as B cells can also turn against healthy tissue - a phenomenon called autoimmunity.
Immunotherapy: a promising antibody
07.10.2019
Acute lymphoblastic leukaemia (ALL) is the most common cancer in children. This form of blood cancer is caused by malignant abnormal precursor cells of certain white blood cells, and usually leads to a rapidly progressive reduction of bone marrow function, and thus impaired blood formation.
Cells: mechanism for the formation of new blood vessels
24.09.2019
Researchers from Uppsala University have revealed for the first time a mechanism for how new blood vessels are formed and have shown the importance of this mechanism for embryo survival and organ function. The results could be developed to control the formation of new blood vessels in different diseases. The new study is published in the journal EMBO Reports.
DNA: held together by hydrophobic forces
23.09.2019
Researchers at Chalmers University of Technology, Sweden, disprove the prevailing theory of how DNA binds itself. It is not, as is generally believed, hydrogen bonds which bind together the two sides of the DNA structure. Instead, water is the key. The discovery opens doors for new understanding in research in medicine and life sciences. The researchers' findings are presented in the journal PNAS.
Organ-on-a-chip systems: limited validity?
01.02.2019
Organ-on-a-chip systems are technically a great enhancement of medical research because they facilitate testing of active ingredients on cell cultures in the chambers of a plastic chip. This replaces animal testing and improves patient safety. That being said, they are not a true-to-life replication of the human body and can only simulate a few functions and activities.