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Image: illustration of nanodestructive characterization of stem cell differentiation through exosomal miRNA detection; Copyright: Jin-Ho Lee/Rutgers University-New Brunswick

Nanotechnology: better stem cell transplantation research

15.08.2019

Nanotechnology developed at Rutgers University-New Brunswick could boost research on stem cell transplantation, which may help people with Alzheimer's disease, Parkinson's disease, other neurodegenerative diseases and central nervous system injuries.
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Image:  bone tissue replicated with 3D technology; Copyright: panthermedia.net/eranicle

Regenerative medicine: 'Bone in a dish'

07.08.2019

Like real bone, the material developed at Oregon Health & Science University has a 3D mineral structure populated with living cells, providing a unique model to study bone function, diseases, regeneration.
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Image: sensor; Copyright: Purdue University

Diagnostics: 3D mapping technology to monitor and track cells and tissues

11.07.2019

Medical advancements can come at a physical cost. Often following diagnosis and treatment for cancer and other diseases, patients' organs and cells can remain healed but damaged from the medical condition. In fact, one of the fastest growing medical markets is healing and/or replacing organs and cells already treated, yet remain damaged by cancer, cardiovascular disease and other medical issues.
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Image: elderly man in the lab injecting a liquid into a chip; Copyright: panthermedia.net/matej kastelic

Human-on-a-chip: prediction of in vivo results based on in vitro model

08.07.2019

Hesperos Inc., pioneers of the human-on-a-chip in vitro system has announced the use of its innovative multi-organ model to successfully measure the concentration and metabolism of two known cardiotoxic small molecules over time, to accurately describe the drug behavior and toxic effects in vivo. The findings support the potential of body-on-a-chip systems to transform the drug discovery process.
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Image: schematic of stem cells; Copyright: panthermedia.net/ktsdesign

Cell therapies: homing instinct shows cells "home"

04.07.2019

In a world first, scientists have found a new way to direct stem cells to heart tissue. The findings, led by researchers at the University of Bristol and published in Chemical Science, could radically improve the treatment for cardiovascular disease.
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Image: cells are placed on a microfluidic organ-chip; Copyright: Dr. Gad Vatine/BGU

Blood-brain barrier chip: using stem cells for the first time

18.06.2019

Researchers at Ben-Gurion University of the Negev (BGU) and Cedars-Sinai Medical Center in Los Angeles have, for the first time, duplicated a patient's blood-brain barrier (BBB), creating a human BBB chip with stem cells, which can be used to develop personalized medicine and new techniques to research brain disorders.
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Image: microscope images of the human Blood-Brain Barrier-on-Chip; Copyright: Wyss Institute at Harvard University

Blood-Brain Barrier Chip: in vivo-like drug and antibody transport

17.06.2019

Like airport security barriers that either clear authorized travelers or block unauthorized travelers and their luggage from accessing central operation areas, the blood-brain-barrier (BBB) tightly controls the transport of essential nutrients and energy metabolites into the brain and staves off unwanted substances circulating in the blood stream.
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Image: Hydrogel for wound healing; Copyright: Jeff Fitlow/Rice University

Wound healing: Molecular bait for hydrogels

12.06.2019

The team led by Brown School of Engineering bioengineer Antonios Mikos and graduate student Jason Guo have developed modular, injectable hydrogels enhanced by bioactive molecules anchored in the chemical crosslinkers that give the gels structure.
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Image: A coloured microscopic image of an organoid; Copyright: Cincinnati Children's

Organ-on-a-chip: Bioengineered human liver disease

04.06.2019

Scientists successfully bioengineered human liver organoids that faithfully mimic key features of fatal liver disease in the laboratory. This allowed them to uncover underlying disease biology in the organoids and test a potential therapy that in preclinical lab tests reversed an often-fatal childhood condition called Wolman disease.
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Image: blood sample tubes; Copyright: panthermedia.net / scanrail

Blood test: How effective is stem cell transplantation?

24.05.2019

University of Maryland School of Medicine study shows the potential of transplanted stem cell secretions as a liquid biopsy.
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Image: Graphic rendering of several cells in a petri dish; Copyright: panthermedia.net/dani3315

Organ-on-a-chip systems: limited validity?

01.02.2019

Organ-on-a-chip systems are technically a great enhancement of medical research because they facilitate testing of active ingredients on cell cultures in the chambers of a plastic chip. This replaces animal testing and improves patient safety. That being said, they are not a true-to-life replication of the human body and can only simulate a few functions and activities.
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