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Image: Laboratory tests to identify cancer cells; Copyright: panthermedia.net/Sven Hoppe

Biomarker: Which pancreatic cysts may become cancerous?

10.06.2019

Cysts in the pancreas sometimes develop into the invasive cancer, depending on the type of cyst, but such growths often are not cancerous, creating a quandary for physicians who spot them via CT and MRI scans. Surgery to remove pancreatic cysts is often complex, so there is a need for new tools to identify which such cysts are most likely to develop into cancer and which are not.
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Image: A coloured microscopic image of an organoid; Copyright: Cincinnati Children's

Organ-on-a-chip: Bioengineered human liver disease

04.06.2019

Scientists successfully bioengineered human liver organoids that faithfully mimic key features of fatal liver disease in the laboratory. This allowed them to uncover underlying disease biology in the organoids and test a potential therapy that in preclinical lab tests reversed an often-fatal childhood condition called Wolman disease.
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Image: two men in the laboratory next to the Organ Care System with a pig's lung inside; Copyright: Kaiser/MHH

Organ Care System: treatment under extreme conditions

08.05.2018

Multidrug-resistant organisms that are treated with a dosage that exceeds the regular dose a hundred times and at temperatures of over 40 degrees Celsius – the human organism is unable to handle it. Yet if the diseased organ is treated outside of the body, extreme conditions are an option. For the first time, physicians have succeeded in treating a severe case of pneumonia by using the OCS.
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Image: Preview picture of video

Photochemical internalization – A new hope against bile duct cancer?

03.07.2017

Advanced bile duct tumors cannot always be removed surgically. Then, patients receive chemotherapy and a stent that corrects the narrowing of the bile duct that is caused by the tumor. Another, local therapy option is tested at the University Hospital Frankfurt: laser light is used to transport drugs into the tumor during photochemical internalization.
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Image: A women with a bald head and a headscarf, smiling, sitting on a sofa talking ot another woman; Copyright:Katharina Bia asiewic

Irreversible Electroporation – Last hope for liver cancer patients

24.04.2017

Liver cancer is the fifth most common malignant tumor in the world. The tumor can be removed through surgery or by utilizing thermal ablation techniques. If a treatment with conservative methods is no longer possible, there is an alternative: irreversible electroporation (IRE). The effectiveness of this method was now confirmed by a clinical study.
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