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Diagnostics: Animal blood samples help predict human diseases
17.07.2019
Penguins, Asian elephants and many other animal species live in the zoos of Saarbrücken and Neunkirchen. As they come from different continents, blood is regularly taken from the animals to check their health.
Biomarker: test improves prostate cancer detection
03.07.2019
A team of researchers from UCLA and the University of Toronto have identified a new biomarker found in urine that can help detect aggressive prostate cancer, potentially saving hundreds of thousands of men each year from undergoing unnecessary surgeries and radiotherapy treatments.
Diagnostics: A rapid, easy-to-use DNA amplification method
19.06.2019
Scientists in Japan have developed a way of amplifying DNA on a scale suitable for use in the emerging fields of DNA-based computing and molecular robotics. By enabling highly sensitive nucleic acid detection, their method could improve disease diagnostics and accelerate the development of biosensors, for example, for food and environmental applications.
Microfluidic sensor: monitoring sickle cell disease
19.06.2019
Sickle cell disease is a hereditary disorder that affects red blood cells, distorting their natural disc shape into a crescent moon or "sickle" shape. Normal red blood cells move freely through small vessels throughout the body to deliver oxygen. With sickle cell disease, the misshapen red blood cells become hard and sticky, making it difficult for them to move through blood vessels.
Functional Imaging: The puls of modern oncology
17.06.2019
Medical imaging techniques have developed considerably in recent decades. In addition to morphological imaging techniques more and more functional imaging techniques are used in oncology that can continously record the functions of specific organs locally and regionally in real time. These are groundbreaking for diagnostics, therapies and preoperative preparations.
Biomarker: Which pancreatic cysts may become cancerous?
10.06.2019
Cysts in the pancreas sometimes develop into the invasive cancer, depending on the type of cyst, but such growths often are not cancerous, creating a quandary for physicians who spot them via CT and MRI scans. Surgery to remove pancreatic cysts is often complex, so there is a need for new tools to identify which such cysts are most likely to develop into cancer and which are not.
Advance in genome analysis: DNA tests for patients move closer
05.06.2019
Diseases caused by genetic changes could be detected more readily thanks to an advance in DNA analysis software. The development will make it easier to integrate genetic testing into health care systems such as the UK's National Health Service, which cares for around three million people affected by genetic diseases in the UK.
Organ-on-a-chip: Bioengineered human liver disease
04.06.2019
Scientists successfully bioengineered human liver organoids that faithfully mimic key features of fatal liver disease in the laboratory. This allowed them to uncover underlying disease biology in the organoids and test a potential therapy that in preclinical lab tests reversed an often-fatal childhood condition called Wolman disease.
Diagnostics: biomarkers help tailor diuretic use in acute heart failure patients
31.05.2019
Adrenomedullin activity predicts which acute heart failure patients are at the greatest risk of death without diuretic treatment post-discharge, according to late breaking research presented today at Heart Failure 2019, a scientific congress of the European Society of Cardiology (ESC).
Diagnostic test: simple test can tell if you're stressed out
29.05.2019
Stress is often called "the silent killer" because of its stealthy and mysterious effects on everything from heart disease to mental health. Now researchers at the University of Cincinnati have developed a new test that can easily and simply measure common stress hormones using sweat, blood, urine or saliva.
Diagnostic test: biomarker can diagnose Alzheimer's in its earliest stages
27.05.2019
Alzheimer's disease is the major cause of dementia and so far, no effective treatment can prevent, delay or stop its progression. We know that AD has an extensive prodromal stage (with initial symptoms preceding the disease) which lasts 15 to 20 years before clinical signs are evident. To envision an effective treatment for AD, we need to be able to accurately diagnose AD at its earliest stages.
Blood test: How effective is stem cell transplantation?
24.05.2019
University of Maryland School of Medicine study shows the potential of transplanted stem cell secretions as a liquid biopsy.
Assistance systems: AI radio for people with dementia
21.05.2019
Radio Me will address key causes of hospital admission for people with dementia, such as agitation and not taking medication correctly. As a result, it is hoped quality of life will improve, and people will be able to remain living independently at home for longer.
Nanotechnology: magnetic beads to treat preeclampsia
16.05.2019
Preliminary laboratory tests show that functionalized magnetic beads successfully reduced blood levels of a harmful molecule that is elevated during preeclampsia, according to new research in the American Heart Association's journal Hypertension.
Diagnostics: Novel device for Parkinson’s disease
13.05.2019
Presently there are no disease-modifying therapies for the treatment of Parkinson’s disease; however, one potential strategy for treatment is to prevent α-synuclein aggregation. As a first step, researchers at Osaka University have developed a device that can assess the degree of α-synuclein aggregation in the brain.
Laboratory medicine: new method for liquid biopsies
07.05.2019
Advancing technology is allowing scientists increasingly to search for tiny signs of cancer and other health issues in samples of patients' blood and urine. These "liquid biopsies" are less invasive than a traditional biopsy, and can provide information about what's happening throughout the body instead of just at a single site.
Analzing system: Breakthrough designation KidneyIntelX™
03.05.2019
Renalytix AI plc (AIM: RENX), a developer of artificial intelligence-enabled clinical diagnostics for kidney disease, announces that it has been granted Breakthrough Device designation by the U.S. Food and Drug Administration (FDA), for its lead diagnostic, KidneyIntelX™. This is the first such designation for an AI-enabled diagnostic for kidney disease publicly announced by any company.
Early detection: Tattoo signals cancer – and more
09.07.2018
People who are not ill and do not show any symptoms typically do not visit the doctor. And while most people know that preventive medical checkups for cancer, for example, are important, they still avoid them. They tend to be very hesitant because the doctor might detect a serious illness. In the future, a new type of implant could make it easier to go to a screening test.
Personalized cancer medicine – Best possible treatment with TherapySelect
30.04.2018
Medicine is getting more and more personalized. This is particularly interesting for oncology, since a cancer is as individual as the respective patient. When choosing a therapy, both the characteristics of the tumor and the personal characteristics of the patient must be considered. To see exactly what this looks like, we visited the diagnostics company TherapySelect, based in Heidelberg.
Personalized medicine: a paradigm shift is gaining momentum
01.03.2018
Personalized medicine does not follow a "one-size-fits-all" treatment approach but emphasizes a "tailor-made" paradigm, meaning a treatment is customized to each individual person's case. For patients, this increases the chances of treatment success and means fewer side effects. While the approach originates in the field of oncology, it is now also increasingly applied to other disease patterns.
Acute kidney injury: Early detection thanks to biomarker
08.11.2017
Major surgeries in the abdominal region often result in kidney injury in patients. Meanwhile, the clinical manifestations don't present until one or two days after the procedure. This causes physicians to lose valuable time to treat patients. The University Hospital Regensburg has researched a new concept for the treatment of kidney injuries for several years.
Prenatal diagnosis: genetic analysis using droplet PCR
24.07.2017
A new analysis method that uses fetal DNA extracted from the mother’s blood is designed to non-invasively reach a prenatal diagnosis of genetic disorders in a child. A task force of the Hahn Schickard Society for Applied Research is an active part of the "ANGELab" project and co-developed this diagnostic procedure.
Laboratory medicine: confronting infections with speed and foresight
03.04.2017
The laboratory is one of the most important and pivotal bastions in patient care. In the laboratory, acute, chronic and genetic diseases are diagnosed, the progression of diseases such as diabetes is regularly checked or specialists look for biomarkers to adapt cancer therapies.