News from the Editors -- MEDICA - World Forum for Medicine

MEDICA Newsletter

Social Media

Image: Man with a green glove is holding a circuit implant in front of the camera; Copyright: EPFL 2019/ Murielle Gerber

Circuit implant: releasing painkillers inside the body

09.08.2019

Researchers in EPFL's Microsystems Laboratory are now working on a biodegradable implant that would release a local anesthetic on-demand over several days. Not only would this implant reduce patients' post-op discomfort, but there would be no need for further surgery to remove it.
Read more
Image: fingers holding the flexible sensor; Copyright: John Toon, Georgia Tech

Health monitoring: soft wearable uses stretchable electronics

01.08.2019

A wireless, wearable monitor built with stretchable electronics could allow comfortable, long-term health monitoring of adults, babies and small children without concern for skin injury or allergic reactions caused by conventional adhesive sensors with conductive gels.
Read more
Image: elderly man in the lab injecting a liquid into a chip; Copyright: panthermedia.net/matej kastelic

Human-on-a-chip: prediction of in vivo results based on in vitro model

08.07.2019

Hesperos Inc., pioneers of the human-on-a-chip in vitro system has announced the use of its innovative multi-organ model to successfully measure the concentration and metabolism of two known cardiotoxic small molecules over time, to accurately describe the drug behavior and toxic effects in vivo. The findings support the potential of body-on-a-chip systems to transform the drug discovery process.
Read more
Image: cells are placed on a microfluidic organ-chip; Copyright: Dr. Gad Vatine/BGU

Blood-brain barrier chip: using stem cells for the first time

18.06.2019

Researchers at Ben-Gurion University of the Negev (BGU) and Cedars-Sinai Medical Center in Los Angeles have, for the first time, duplicated a patient's blood-brain barrier (BBB), creating a human BBB chip with stem cells, which can be used to develop personalized medicine and new techniques to research brain disorders.
Read more
Image: microscope images of the human Blood-Brain Barrier-on-Chip; Copyright: Wyss Institute at Harvard University

Blood-Brain Barrier Chip: in vivo-like drug and antibody transport

17.06.2019

Like airport security barriers that either clear authorized travelers or block unauthorized travelers and their luggage from accessing central operation areas, the blood-brain-barrier (BBB) tightly controls the transport of essential nutrients and energy metabolites into the brain and staves off unwanted substances circulating in the blood stream.
Read more
Image: Cell cultivation in a Petri dish; Copyright: panthermedia.net / matej kastelic

Organ-on-a-chip – Organs in miniature format

01.02.2019

In vitro processes and animal tests are used to develop new medications and novel therapeutic approaches. However, animal testing raises important ethical concerns. Organ-on-a-chip models promise to be a feasible alternative. In a system the size of a smartphone, organs are connected using artificial circulation.
Read more
Image: Graphic rendering of several cells in a petri dish; Copyright: panthermedia.net/dani3315

Organ-on-a-chip systems: limited validity?

01.02.2019

Organ-on-a-chip systems are technically a great enhancement of medical research because they facilitate testing of active ingredients on cell cultures in the chambers of a plastic chip. This replaces animal testing and improves patient safety. That being said, they are not a true-to-life replication of the human body and can only simulate a few functions and activities.
Read more
Image: Collage made of two images, one show a round, transparent plastic disc with micro channels, one shows a plastic chip; Copyright: Hahn-Schickard, Image Bernd Müller

Prenatal diagnosis: genetic analysis using droplet PCR

24.07.2017

A new analysis method that uses fetal DNA extracted from the mother’s blood is designed to non-invasively reach a prenatal diagnosis of genetic disorders in a child. A task force of the Hahn Schickard Society for Applied Research is an active part of the "ANGELab" project and co-developed this diagnostic procedure.
Read more
Photo: Preview picture of video

Light instead of darkness – Seeing with the Argus II Implant

29.03.2017

Retinitis pigmentosa is a hereditary eye disorder, which can lead to night blindness, restriction of the peripheral visual field and ultimately to blindness. The University Hospital Aachen, Germany, implants the Argus II retinal prosthesis system made by the Second Sight Company. It allows people with retinitis pigmentosa to perceive light and improve orientation.
Read more