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Image: immunofluorescence of spleen sections of a mice; Copyright: IMP

Pathogens: a mechanism to control autoimmunity

08.10.2019

The immune system relies on B cells and their ability to make antibodies against an extremely broad range of pathogens. This broad responsiveness bears some risk, as B cells can also turn against healthy tissue - a phenomenon called autoimmunity.
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Image: detail of the microneedle biosensor; Copyright: Imperial College London

Biosensor: detecting patient's antibiotic levels with microneedles

02.10.2019

Small, non-invasive patches worn on the skin can accurately detect the levels of medication in a patient's system, matching the accuracy of current clinical methods. In a small-scale clinical evaluation, researchers at Imperial College London have shown for the first time how microneedle biosensors can be used to monitor the changing concentration of antibiotics.
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Image: bacterial syringe structure on a black background; Copyright: Shikuma Lab

Bacteriology: structures can be tapped to deliver drugs

19.09.2019

Not all bacteria spread diseases, many are beneficial and this strain has nanoscale syringes that deliver proteins which cause metamorphosis in marine animals, and could be modified as a novel drug delivery tool for future vaccines and cancer care.
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Image: purple microscope image of squamous cell carcinoma of the lung and squamous cell carcinoma of the head and neck; Copyright: Jurmeister/Charité

Machine Learning: improving the diagnosis of head and neck cancers

16.09.2019

Researchers from Charité - Universitätsmedizin Berlin and the German Cancer Consortium have successfully solved a longstanding problem in the diagnosis of head and neck cancers. Working alongside colleagues from TU Berlin, the researchers used artificial intelligence to develop a new classification method which identifies the primary origins of cancerous tissue based on chemical DNA changes.
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Image: DNA strand; Copyright: panthermedia.net/everythingposs

Analyzing systems: technique stores cellular 'memory' in DNA

29.08.2019

Engineers program human and bacterial cells to keep a record of complex molecular events. Using a technique that can precisely edit DNA bases, MIT researchers have created a way to store complex "memories" in the DNA of living cells, including human cells.
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Image: woman in a lab coat and disposable gloves choosing a sample from the brain bank; Copyright: UC Davis Health

AI: mapping the brain landscape for Alzheimer's disease

16.08.2019

A team of researchers lead by Brittany Dugger of UC Davis Health has been awarded a $3.8 million grant from the National Institute for Aging (NIA) to help define the neuropathology of Alzheimer's disease in Hispanic cohorts.
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Image: Laboratory situation - Prof. Popp shows a young man a small object in his hand; Copyright: Leibniz-IPHT/Sven Döring

Tumor excision: triple imaging for unique diagnostics

08.08.2019

After their tumor has been removed, some patients have to return to the hospital to undergo surgery again. That's because the tumor was not precisely identified and was subsequently not completely removed. That's both an ethical and financial dilemma. A new surgery-adjacent procedure is designed to rapidly and accurately detect tumors.
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Image: A greenly lit laboratory device; Copyright: Sven Döring

Photonics: "We want a rapid and easy method to identify pathogens and antibiotic resistance"

01.08.2019

The medical devices value chain has gaps between academic research and industrial practice that slow down innovation processes. This also applies to time-sensitive and urgently needed products such as rapid diagnostic tests to identify resistant pathogens. At the InfectoGnostics Research Campus in Jena, partners from research and medicine team up to close these gaps.
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Image: bacteria-killing gel; Copyrigh: JD Howell, McMaster University

Desinfection: gel heals itself while healing you

26.07.2019

McMaster researchers have developed a novel new gel made entirely from bacteria-killing viruses.
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Image: Graphic rendering of several cells in a petri dish; Copyright: panthermedia.net/dani3315

Organ-on-a-chip systems: limited validity?

01.02.2019

Organ-on-a-chip systems are technically a great enhancement of medical research because they facilitate testing of active ingredients on cell cultures in the chambers of a plastic chip. This replaces animal testing and improves patient safety. That being said, they are not a true-to-life replication of the human body and can only simulate a few functions and activities.
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Image: Maria Driesel and her colleagues from inveox next to the new device; Copyright: Astrid Eckert

Pathology 4.0 – inveox automates laboratory processes

22.08.2018

Mix-ups, contamination and sample loss – most errors in pathology happen when specimen are received. Countless samples arrive daily at the laboratory, while the sample entry process is very monotonous. As a result, the work is inefficient. The start-up company inveox has now developed a system that automates the processes in the pathology laboratory, thus making them more efficient.
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Image: Three-dimensional image of a colored vessel structure; Copyright: René Hägerling

Pathology: detecting lymphedema with 3D microscopy

23.10.2017

According to the WHO, 300 million people throughout the world are affected by lymphedema. This condition occurs when fluid that flows between cells is no longer transported back into the blood circulation and accumulates in the skin. Triggers can be surgeries, injuries or genetic defects for example. A new microscopy technique could now also indicate the causes.
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