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Image: Colorful computer-generated rendering of damaged cartilage tissue; Copyright: Brian Bay, Oregon State University

Imaging study paves way to better understanding of arthritis

03.12.2019

Oregon State University research has provided the first complete, cellular-level look at what is going on in joints afflicted by osteoarthritis, a debilitating and costly condition that affects nearly one-quarter of adults in the United States.
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Image: Diascopic's iON platform next to a laptop; Diascopic, LLC

AI: startup developing tool for tuberculosis detection

27.11.2019

Diascopic LLC, a Cleveland-based medical research company that develops diagnostic technology, will use a highly competitive federal grant to develop and apply new artificial intelligence (AI) and digital pathology tools for detecting tuberculosis (TB).
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Image: Two screens with picture of the circulatory system in a catheter laboratory; Copyright: panthermedia.net/sudok1

MEDICA TECH FORUM: light-based imaging technique OCT

04.11.2019

Since its inception, MEDICA TECH FORUM has focused on the implementation of innovations and new technologies into clinical practice. 2019 marks the tenth year of the Forum. In honor of its anniversary, we will brighten things up a bit, as one of the focal points will highlight how optical coherence tomography (OCT) uses light to produce images.
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Image: malaria infected blood cells under a microscope; Copyright: S. Kapishnikov

Microscope: malaria pathogen under X-ray

31.10.2019

Around 40 percent of humanity lives in regions affected by malaria, around 200 million people contract the disease every year, and an estimated 600,000 people die as a result. These pathogens are unicellular organisms that settle inside the red blood cells of their hosts and metabolize hemoglobin there to grow and multiply.
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Image: immunofluorescence of spleen sections of a mice; Copyright: IMP

Pathogens: a mechanism to control autoimmunity

08.10.2019

The immune system relies on B cells and their ability to make antibodies against an extremely broad range of pathogens. This broad responsiveness bears some risk, as B cells can also turn against healthy tissue - a phenomenon called autoimmunity.
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Image: detail of the microneedle biosensor; Copyright: Imperial College London

Biosensor: detecting patient's antibiotic levels with microneedles

02.10.2019

Small, non-invasive patches worn on the skin can accurately detect the levels of medication in a patient's system, matching the accuracy of current clinical methods. In a small-scale clinical evaluation, researchers at Imperial College London have shown for the first time how microneedle biosensors can be used to monitor the changing concentration of antibiotics.
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Image: bacterial syringe structure on a black background; Copyright: Shikuma Lab

Bacteriology: structures can be tapped to deliver drugs

19.09.2019

Not all bacteria spread diseases, many are beneficial and this strain has nanoscale syringes that deliver proteins which cause metamorphosis in marine animals, and could be modified as a novel drug delivery tool for future vaccines and cancer care.
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Image: purple microscope image of squamous cell carcinoma of the lung and squamous cell carcinoma of the head and neck; Copyright: Jurmeister/Charité

Machine Learning: improving the diagnosis of head and neck cancers

16.09.2019

Researchers from Charité - Universitätsmedizin Berlin and the German Cancer Consortium have successfully solved a longstanding problem in the diagnosis of head and neck cancers. Working alongside colleagues from TU Berlin, the researchers used artificial intelligence to develop a new classification method which identifies the primary origins of cancerous tissue based on chemical DNA changes.
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Image: Laboratory situation - Prof. Popp shows a young man a small object in his hand; Copyright: Leibniz-IPHT/Sven Döring

Tumor excision: triple imaging for unique diagnostics

08.08.2019

After their tumor has been removed, some patients have to return to the hospital to undergo surgery again. That's because the tumor was not precisely identified and was subsequently not completely removed. That's both an ethical and financial dilemma. A new surgery-adjacent procedure is designed to rapidly and accurately detect tumors.
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Image: A greenly lit laboratory device; Copyright: Sven Döring

Photonics: "We want a rapid and easy method to identify pathogens and antibiotic resistance"

01.08.2019

The medical devices value chain has gaps between academic research and industrial practice that slow down innovation processes. This also applies to time-sensitive and urgently needed products such as rapid diagnostic tests to identify resistant pathogens. At the InfectoGnostics Research Campus in Jena, partners from research and medicine team up to close these gaps.
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Image: Graphic rendering of several cells in a petri dish; Copyright: panthermedia.net/dani3315

Organ-on-a-chip systems: limited validity?

01.02.2019

Organ-on-a-chip systems are technically a great enhancement of medical research because they facilitate testing of active ingredients on cell cultures in the chambers of a plastic chip. This replaces animal testing and improves patient safety. That being said, they are not a true-to-life replication of the human body and can only simulate a few functions and activities.
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Image: Maria Driesel and her colleagues from inveox next to the new device; Copyright: Astrid Eckert

Pathology 4.0 – inveox automates laboratory processes

22.08.2018

Mix-ups, contamination and sample loss – most errors in pathology happen when specimen are received. Countless samples arrive daily at the laboratory, while the sample entry process is very monotonous. As a result, the work is inefficient. The start-up company inveox has now developed a system that automates the processes in the pathology laboratory, thus making them more efficient.
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Image: Three-dimensional image of a colored vessel structure; Copyright: René Hägerling

Pathology: detecting lymphedema with 3D microscopy

23.10.2017

According to the WHO, 300 million people throughout the world are affected by lymphedema. This condition occurs when fluid that flows between cells is no longer transported back into the blood circulation and accumulates in the skin. Triggers can be surgeries, injuries or genetic defects for example. A new microscopy technique could now also indicate the causes.
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