08.07.2019Hesperos Inc., pioneers of the human-on-a-chip in vitro system has announced the use of its innovative multi-organ model to successfully measure the concentration and metabolism of two known cardiotoxic small molecules over time, to accurately describe the drug behavior and toxic effects in vivo. The findings support the potential of body-on-a-chip systems to transform the drug discovery process.
05.07.2019Researchers at Sandia National Laboratories identified the weakness and notified the software developers. The issue has also been fixed in the latest release of the software. While no attack from this vulnerability is known, the National Institutes of Standards and Technology recently described it in a note to software developers, genomics researchers and network administrators.
28.06.2019Click, swipe, listen to patients and follow the talk among the healthcare staff. Now, another step in the work towards a more person-centred care is being taken as the PCC Game app is being launched. A virtual journey for greater knowledge and with tricky questions along the way.
18.06.2019Researchers at Ben-Gurion University of the Negev (BGU) and Cedars-Sinai Medical Center in Los Angeles have, for the first time, duplicated a patient's blood-brain barrier (BBB), creating a human BBB chip with stem cells, which can be used to develop personalized medicine and new techniques to research brain disorders.
17.06.2019Medical imaging techniques have developed considerably in recent decades. In addition to morphological imaging techniques more and more functional imaging techniques are used in oncology that can continously record the functions of specific organs locally and regionally in real time. These are groundbreaking for diagnostics, therapies and preoperative preparations.
17.06.2019Like airport security barriers that either clear authorized travelers or block unauthorized travelers and their luggage from accessing central operation areas, the blood-brain-barrier (BBB) tightly controls the transport of essential nutrients and energy metabolites into the brain and staves off unwanted substances circulating in the blood stream.
12.06.2019Machine learning has the potential to vastly advance medical imaging, particularly computerized tomography (CT) scanning, by reducing radiation exposure and improving image quality. Those new research findings were just published in Nature Machine Intelligence by engineers at Rensselaer Polytechnic Institute and radiologists at Massachusetts General Hospital and Harvard Medical School.
04.06.2019Tendinitis, myofascial pain syndromes or fractures - shock wave therapy is a noninvasive method with no side effects that promises relief. The intensity of the shock waves can be customized to meet patients’ needs and yields fast positive results. In addition to advising doctor’s offices, clinical facilities, and universities, Kröner Medizintechnik GmbH also offers treatment, support, and care.
28.05.2019Researchers have shown that AI could potentially be used to customise training regimens for individuals to personalise learning and improve cognitive performance. Using performance data from a given person, CURATE.AI creates an individualised profile that enables cognitive training to be tailored to the individual's learning habits and competencies so as to enhance training effectiveness.
27.05.2019Researchers from the University of Copenhagen and Rigshospitalet have used data on more than 230,000 intensive care patients to develop a new algorithm. Among other things, it uses disease history from the past 23 years to predict patients' chances of survival in intensive care units.
23.05.2019UNIGE researchers have developed a cell co-culture platform that can reproduce a patient's tumour in 3D and test the best treatment combinations for its specific case in just five days.
23.05.2019An artificial portable kidney that patients who have suffered renal failure could wear is to be created by a research team at the University of Saskatchewan with federal funding.
22.05.2019Deep learning - a form of artificial intelligence - was able to detect malignant lung nodules on low-dose chest computed tomography (LDCT) scans with a performance meeting or exceeding that of expert radiologists, reports a new study from Google and Northwestern Medicine.
21.05.2019Radio Me will address key causes of hospital admission for people with dementia, such as agitation and not taking medication correctly. As a result, it is hoped quality of life will improve, and people will be able to remain living independently at home for longer.
21.05.2019An app that allows parents and doctors to monitor a child's asthma has a big impact on managing the disease. When families monitored symptoms with eAsthma Tracker and adjusted care accordingly, children had better asthma control and made fewer visits to the emergency department.
15.05.2019New active substances that are suitable for drugs are initially tested in animal experiments. However, the results cannot always be transferred to the human organism. At the Karlsruhe Institute of Technology, Prof. Ute Schepers from vasQlab explains how active substances can be tested in human tissue without endangering human health.
14.05.2019Researchers from two major institutions have developed a new tool with advanced artificial intelligence (AI) methods to predict a woman's future risk of breast cancer.
10.05.2019A simple innovation the size of a grain of sand means we can now analyse cells and tiny particles as if they were inside the human body. The new micro-device for fluid analysis will enable more tailored experiments in drug development and disease research via new 'organ-on-chip' systems.
06.05.2019To model human health and disease, organ-on-a-chip technology mimics the human body's organ structure, functionality and physiology in a controlled environment. These miniature systems, which serve as accurate models of various organs from the heart and lungs to the gut and the kidneys, can use a patient's own cells to test drugs and understand disease processes.
06.05.2019A faculty-researcher at Rochester Institute of technology has developed a prototype micro device with bio-sensors that can detect the deadly Ebola virus. With this type of device, those infected can be treated earlier, and the early detection process can potentially decrease the spread of infections.
03.05.2019Renalytix AI plc (AIM: RENX), a developer of artificial intelligence-enabled clinical diagnostics for kidney disease, announces that it has been granted Breakthrough Device designation by the U.S. Food and Drug Administration (FDA), for its lead diagnostic, KidneyIntelX™. This is the first such designation for an AI-enabled diagnostic for kidney disease publicly announced by any company.
30.04.2019Researchers of Kaunas University of Technology (KTU), the Lithuanian University of Health Sciences (LSMU) and Italian high-tech company Gruppo Fos Lithuania are developing a technology for the personalised care of the patients who have experienced a stroke. After collecting data of physiological parameters, the multimodal system will choose personalised rehabilitation solutions for each patient.
30.04.2019A breast cancer test has been found that helps doctors make treatment decisions for some breast cancer patients, following research carried out at Queen Mary University of London and funded by Cancer Research UK.
26.04.2019Columbia engineers develop a new platform that recreates cancer in a dish to quickly determine the best bacterial therapy.
23.04.2019They are working in the background, but the things they do often decide about the right therapy or can even be life savers: labs and laboratory technology are probably the most important part of today’s medicine. This is why World Laboratory Day aims to draw attention to this "hidden" part of medicine.
01.04.2019A surgery already begins before the patient is lying on the operating table – namely with the planning. For example, if brain surgery is imminent, the brain must first be mapped. This makes the activity level of certain brain areas visible. Functional magnetic resonance imaging makes this possible.
01.04.2019Our brain is the command center of our body. This is where all information and impressions are collected and converted into responses and movements. Modern imaging techniques offer physicians and researchers unique insights into the actions of the human central nervous system. The functional imaging technique allows them to watch our brain in action.
01.03.2019COPD affects more than 200 million people in the world. Those affected by this chronic pulmonary disease are often slow to notice the symptoms and get a medical diagnosis. This results in secondary complications and high medical costs. That's why an early diagnosis, comprehensive treatment, and frequent monitoring are very important. Various devices and tools support this all-round care.
01.03.2019Coughing, airway obstruction, difficulty breathing: Chronic obstructive pulmonary disease (COPD) is an umbrella term used to describe progressive and currently incurable lung diseases. The innovative solutions of Philips Respironics help patients to manage each stage of the disease and their medication intake, train the respiratory system and provide respiratory support.
01.02.2019In vitro processes and animal tests are used to develop new medications and novel therapeutic approaches. However, animal testing raises important ethical concerns. Organ-on-a-chip models promise to be a feasible alternative. In a system the size of a smartphone, organs are connected using artificial circulation.
01.02.2019The liver, nervous tissue or the intestines: all are important human organs that have in the past been tested for their function and compatibility using animal or in vitro test methods. In recent years, TissUse GmbH, a spin-off of the Technical University of Berlin (TU Berlin), has launched multi-organ chip platforms. But that’s not all.
08.01.2019Parkinson's disease is a progressive nervous system disorder that primarily affects movement of patients and makes their everyday lives very challenging. It also makes regular doctor appointments and treatment sessions necessary. "TelePark" - a project that collects different movement-related parameters using sensors and apps is designed to improve the quality of life for Parkinson’s patients.
02.01.2019Diabetes mellitus or simply diabetes has become very common and is often described as a lifestyle disease. More and more people are suffering from this chronic metabolic disorder. Next to established diagnostic procedures, digital retinal screening has shown to be successful - a promising technique that will also play an important role in the diagnosis of other diseases in the future.
19.12.2018Continuous monitoring is an essential process with every disease. In the case of eye disorders, frequent retina measurements can facilitate early detection of deterioration to quickly initiate intervention. This calls for comprehensive care settings, easy ways to take measurements and prompt results. However, in reality, this is rarely the case.
03.12.2018Strengthening and healing thanks to the power of electrical pulses - is that really possible? When mobility is restricted or muscles are no longer as strong as they used to be, electrical treatment options can lead to improvement or even cure of diseases. But why are more and more people turning to these alternatives, what are the advantages and what are their limitations and drawbacks?
22.11.2018Every year between 250.000 and 500.000 people suffer a spinal cord injury, MoreGrasp is intended to make their lives easier. The project aims to restore the lost gripping function in people with high paraplegia. Researchers at Graz University of Technology have developed a neuroprosthesis that is currently undergoing a feasibility study.
08.11.2018Not enough exercise, an unhealthy diet: Kidney stones develop when urine contains too many insoluble compounds and are now one of the most common diseases worldwide. The ailment annually affects 1.2 million people in Germany alone. The stones are broken up and taken out via endoscopic surgery. Now it’s possible to remove even the tiniest residual fragments. The solution: a biocompatible adhesive.
02.11.2018It’s safe to say that patients and their prompt medical care take center stage at any hospital. Digitization of the healthcare sector is quickly advancing to make this a reality: data is stored in a digital medium, devices are linked together. But how safe are hospitals in the age of innovation?
02.11.2018This is what diagnostic investigation normally looks like: a patient sample is collected, sent to the laboratory and analyzed. Once that's completed, the patient is told of the lab test result. But if the patient is a high-performance athlete and has to follow and stick to a rigid training schedule, he or she needs these results immediately. What makes this possible? Point-of-care testing!
22.10.2018Today’s society is faced with an aging population. The past has seen the development of many methods for measuring body composition in older adults. However, some of these techniques are not available to medical practices and hospital facilities or are in dire need of optimization.
08.10.2018Did you know that we can influence up to 50 percent of our health ourselves? If we eat a balanced diet and exercise regularly, this not only ensures longer independence in old age. Diseases can also be treated with exercise. But in many cases, physicians and patients still rely more on medication than on exercise.
05.10.2018Many people have damaged or suboptimally functioning lungs. An accurate diagnosis and subsequent treatment are vital to protect this life-sustaining organ. Modern imaging solutions help physicians and patients understand what happens inside the lungs.
10.09.2018About eight in ten Germans suffer from back pain during their lifetime. Too much or the wrong movements can also cause problems. "Ran Rücken", the interdisciplinary research project aims to determine the right minimum dose of exercise that proves effective. (Explanatory note: "Ran Rücken" can be loosely translated as "Target the Back")
03.09.2018Artificial intelligence makes the diagnosis, robots perform the surgery and physicians manage all processes via touchscreen – is that what hospitals of the future will look like? And how far away are we actually from this future? Many hospital facilities are already on their way to becoming Smart Hospitals with the latest technology and where everything and everyone is linked and connected.
01.08.2018All of us generate data every day without even realizing it – sometimes it happens unconsciously and unintentionally. At this point, we are made of data and not just in the eyes of tech companies but also from a healthcare system perspective. Our electronic health records are a smorgasbord of data for example.
30.04.2018Medicine is getting more and more personalized. This is particularly interesting for oncology, since a cancer is as individual as the respective patient. When choosing a therapy, both the characteristics of the tumor and the personal characteristics of the patient must be considered. To see exactly what this looks like, we visited the diagnostics company TherapySelect, based in Heidelberg.
23.04.2018A bypass is a complicated structure. It is either made of synthetic materials that can cause blood clots and infections or created by using the patient’s veins. However, the latter often does not yield adequate material. A newly developed bioreactor could solve this problem in the future. It is designed to tissue engineer vascular grafts by using the body’s own material.
01.03.2018Personalized medicine does not follow a "one-size-fits-all" treatment approach but emphasizes a "tailor-made" paradigm, meaning a treatment is customized to each individual person's case. For patients, this increases the chances of treatment success and means fewer side effects. While the approach originates in the field of oncology, it is now also increasingly applied to other disease patterns.
01.03.2018Conventional cancer treatment selection typically depends on the location of the tumor. However, this approach ignores the distinct gene mutations in the tumor of the individual patient. New cancer research approaches increasingly emphasize the concept of personalized therapy.
01.03.2018Everyone is different. This statement also applies to our health. Cancer, in particular, can look and progress differently depending on the individual person. That’s why every patient ideally also needs a customized treatment that is tailored to their individual needs. But how feasible is this idea?
01.08.2017Many therapeutic drugs are very powerful, but they are also very toxic at the same time. Thus, they have to be measured regularly, again and again, so that an adjustment of the individual drug dosage can be made. Until now, the "normal" way was to take the blood sample, send it to a central laboratory and get the results after some days. A new point-of-care test can measure it in 15 minutes.
01.06.2017A stroke, an accident or just because you are aging – there are many reasons to take advantage of physiotherapeutic or rehabilitative measures. More and more new technologies are designed to support patients in this process. They run the gamut from sensor technology and robotics to exergames and virtual reality.
01.06.2017Movement is good for health, but people do it less and less as they age. The Dutch company SilverFit wants to counteract this. Their devices that combine sport and game are primarily aimed at elderly people. Their goal: to give people joy, fun and motivation to move – both in rehabilitation and in daily life.
02.05.2017There are recurring questions that companies are seeking to invest or produce in India. Here are some questions and their answers.
03.04.2017Many aspects are uniformly regulated in Europe, however, hospital hygiene and MRSA prevention, for example, are not. The Netherlands plays a pioneering role in the fight against hospital-acquired infections. The country is an often-cited role model. But can other countries simply adopt the same system? And what makes it so different? MEDICA asked expert Prof. Alexander W. Friedrich.
01.03.2017Genome data, MRI images, and blood test results – data collected in the medical sector is not only very heterogeneous but also extremely extensive. However, it is important to not only collect this data but to also utilize it. After all, processed, linked and analyzed data provides many opportunities in research, hospital management and ultimately also for the individual patient.
01.03.2017In the "KDI – Clinical Data Intelligence Project", researchers are trying to consolidate various types of data to make them useable and useful to both medical professionals and scientists. This is a tremendous undertaking, considering the data volumes from different sources. In this conversation with MEDICA, Dr. Martin Sedlmayr explains the project setup.
12.01.2017Long waiting times in medical practices are not a rarity. The telemedicine can provide remedy. The program of the Institute for Applied Telemedicine at the Heart and Diabetes Center NRW in Bad Oeynhausen is aimed primarily at chronically ill people. Daily, they send their body values via telecommunication to the institute.
02.01.2017Treatments for children need to be different from treatment for adults – this also applies in oncology. Having said that, children do not just need new and different treatment concepts that still necessitate research. They also require the support from their families, who need to be nearby during treatment.