Background Reports 2019 -- MEDICA - World Forum for Medicine

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Functional Imaging: The puls of modern oncology

17.06.2019

Medical imaging techniques have developed considerably in recent decades. In addition to morphological imaging techniques more and more functional imaging techniques are used in oncology that can continously record the functions of specific organs locally and regionally in real time. These are groundbreaking for diagnostics, therapies and preoperative preparations.
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Surgery devices: 'virtual biopsy' device detects skin tumor

14.06.2019

has developed a new "virtual biopsy" device that can quickly determine a skin lesion's depth and potential malignancy without using a scalpel.
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Image: doctor investigates skin of a patient; Copyright: panthermedia.net / belchonock

AI: diagnosis of skin lesions is superior to humans

13.06.2019

When it comes to the diagnosis of pigmented skin lesions, artificial intelligence is superior to humans. In a study conducted under the supervision of the MedUni Vienna human experts "competed" against computer algorithms. The algorithms achieved clearly better results, yet their current abilities cannot replace humans.
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Image: Woman undergoing a CT scan; Copyright: panthermedia.net/Tyler Olsonv

Machine learning: superior results for low-dose CT

12.06.2019

Machine learning has the potential to vastly advance medical imaging, particularly computerized tomography (CT) scanning, by reducing radiation exposure and improving image quality. Those new research findings were just published in Nature Machine Intelligence by engineers at Rensselaer Polytechnic Institute and radiologists at Massachusetts General Hospital and Harvard Medical School.
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Image: Woman investigates cell in a laboratory; Copyright: panthermedia.net/alexraths

Cell analysis: deep learning dive to cell division

10.06.2019

Combining tissue imaging and artificial intelligence, Hollings Cancer Center researchers at the Medical University of South Carolina probed deeper into how cell division cycles are regulated, in this study released online in the May 2019 issue of Cell Reports.
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Image: Laboratory tests to identify cancer cells; Copyright: panthermedia.net/Sven Hoppe

Biomarker: Which pancreatic cysts may become cancerous?

10.06.2019

Cysts in the pancreas sometimes develop into the invasive cancer, depending on the type of cyst, but such growths often are not cancerous, creating a quandary for physicians who spot them via CT and MRI scans. Surgery to remove pancreatic cysts is often complex, so there is a need for new tools to identify which such cysts are most likely to develop into cancer and which are not.
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Image: Man with prostate cancer at the doctor; Copyright: panthermedia.net / imagepointfr

Diagnostic tests: Better detection of prostate cancer

24.05.2019

Prostate cancer is the second-leading cause of male cancer deaths worldwide. Deaths from prostate cancer are primarily due to metastasized cancer, in which cancer cells have migrated through the body and begun to grow in other areas. Results reported in Biomicrofluidics, from AIP Publishing, promise a new way to detect this deadly disease through a simple, inexpensive device.
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Image: woman suffering from colon cancer; Copyright: panthermedia.net / Tharakorn

Diagnostic tests: Identifying cancer treatment in five days

23.05.2019

UNIGE researchers have developed a cell co-culture platform that can reproduce a patient's tumour in 3D and test the best treatment combinations for its specific case in just five days.
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Image: New deep-learning model for lung cancer; Copyright: panthermedia.net / belchonock

AI: System spots lung cancer before radiologists

22.05.2019

Deep learning - a form of artificial intelligence - was able to detect malignant lung nodules on low-dose chest computed tomography (LDCT) scans with a performance meeting or exceeding that of expert radiologists, reports a new study from Google and Northwestern Medicine.
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Image: Researcher with a microfluidic chip; Copyright: panthermedia.net / hquality

Microfluidic chip: New technology to capture tumor cells

20.05.2019

Instead of searching for a needle in a haystack, what if you were able to sweep the entire haystack to one side, leaving only the needle behind? That's the strategy researchers in the University of Georgia College of Engineering followed in developing a new microfluidic device that separates elusive circulating tumor cells (CTCs) from a sample of whole blood.
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Image: woman with breast cancer and child in her arms; Copyright: panthermedia.net / ArturVerkhovetskiy

AI: Novel method predicts future risk of breast cancer

14.05.2019

Researchers from two major institutions have developed a new tool with advanced artificial intelligence (AI) methods to predict a woman's future risk of breast cancer.
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Image: doctor points at an brain imaging; Copyright: panthermedia.net / sudok1

Imaging: New technique uses protein of scorpion venom

13.05.2019

A novel imaging technique that uses a synthesized form of scorpion venom to light up brain tumors has shown promise in a clinical trial. The imaging system enables neurosurgeons to better see malignant growths that often are difficult to fully eliminate.
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Image: man in the laboratory, in front of him a screen; Copyright: Joseph Xu, UM College of Engineering

Laboratory medicine: new method for liquid biopsies

07.05.2019

Advancing technology is allowing scientists increasingly to search for tiny signs of cancer and other health issues in samples of patients' blood and urine. These "liquid biopsies" are less invasive than a traditional biopsy, and can provide information about what's happening throughout the body instead of just at a single site.
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Image: Doctors investigating scans of lung imaging; Copyright: panthermedia.net / likstudio

Imaging: Deep-learning model for lung cancer

02.05.2019

A deep-learning model developed using serial image scans of tumors from patients with non-small cell lung cancer (NSCLC) predicted treatment response and survival outcomes better than standard clinical parameters.
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Image: Graphic of a spinglass of human gene interactions; Copyright: Graeme Benstead-Hume, University of Sussex

Computational system: Algorithms for cancer treatments

02.05.2019

While network algorithms are usually associated with finding friends on social media, researchers at the University of Sussex have shown how they could also be used improve the effectiveness of cancer treatment, by predicting the interactions between genes.
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Image: Stetoscope on a medical document about ovarian cancer; Copyright: panthermedia.net / Premium shots

Imaging: System helps to remove tiny ovarian tumors

01.05.2019

Ovarian cancer is usually diagnosed only after it has reached an advanced stage, with many tumors spread throughout the abdomen. Most patients undergo surgery to remove as many of these tumors as possible, but because some are so small and widespread, it is difficult to eradicate all of them.
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Image: laboratory devices; Copyright: panthermedia.net / Robert Przybysz

Diagnostics: Test for effective treatment of breast cancer

30.04.2019

A breast cancer test has been found that helps doctors make treatment decisions for some breast cancer patients, following research carried out at Queen Mary University of London and funded by Cancer Research UK.
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Image: Child suffering from cancer; Copyright: panthermedia.net / frantab

Software: Advanced radiation therapy for children

29.04.2019

Doctors at Children's Hospital Los Angeles continue to lead the field of radiation oncology by pushing the leading edge of technological advances. A new report by Arthur Olch, PhD, highlights use of specialized software that could advance treatment accuracy for pediatric cancer patients.
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Image: A large number of round microwells on a plate; Copyright: Tetsuhiro Harimoto/Columbia Engineering

Precision medicine: bacterial therapy in a dish

26.04.2019

Columbia engineers develop a new platform that recreates cancer in a dish to quickly determine the best bacterial therapy.
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Image: Laboratory device with a lot of glass vials; Copyright: panthermedia.net/kagemusha

World Laboratory Day 2019 – working behind the scenes of medicine

23.04.2019

They are working in the background, but the things they do often decide about the right therapy or can even be life savers: labs and laboratory technology are probably the most important part of today’s medicine. This is why World Laboratory Day aims to draw attention to this "hidden" part of medicine.
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Image: doctors in front of an MRI Copyright: panthermedia.net/ Arne Trautmann

AI performs as well as experienced radiologists

18.04.2019

UCLA researchers have developed a new artificial intelligence system to help radiologists improve their ability to diagnose prostate cancer. The
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Image: Cryo-EM structure of LA-PTH-bound human PTH1R in complex with Gs; Copyright: Zhao LH et al. 2019

Microscopy: near-atomic map of parathyroid hormone complex

17.04.2019

An international team of scientists has mapped a molecular complex that could aid in the development of better medications with fewer side effects for osteoporosis and cancer.
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Image: hand holding the 3D ultrasound probe; Copyright: Schulich Medicine & Dentistry, Western University

3D ultrasound gives clearer picture to treat gynecological cancer

11.04.2019

New technology developed at Western University is providing an improved way for radiation oncologists to deliver treatment to women with gynaecological cancers, including vaginal, cervical and uterine cancer.
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Image: computational model for cancer treatment; Copyright: Kimberly Sabsay

Computational model for cancer treatment

05.04.2019

Researchers have developed a computational model for human MEK1, a protein with potential as a drug target for a variety of human cancers.
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Image: doctor with stetoscope examines child; Copyright: panthermedia.net / Wong Sze Fei

Imaging: Method to diagnose heart disease in children

04.04.2019

A new study by biomedical engineering researchers at the University of Arkansas could significantly improve methods for detecting and diagnosing congenital heart disease in infants and small children.
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Image: head graphic brain; Copyright: panthermedia.net/ Yuzach

AI for better assessment of brain tumor treatment

03.04.2019

A team from Heidelberg University Hospital and the German Cancer Research Centre has developed a new method for the automated image analysis of brain tumors. In their recent publication, the authors show that machine learning methods carefully trained on standard magnetic resonance imaging (MRI) are more reliable and precise than established radiological methods in the treatment of brain tumors.
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Image: a woman during a MRI; Copyright: panthermedia.net/SimplePhoto

Imaging: Contrast-enhanced MRI provides useful findings

02.04.2019

An essential part of breast intervention is the process of assessing concordance between imaging findings and core biopsy results. When pathology results are considered benign discordant, current standard of care is surgical excision, even though many of these lesions will ultimately be found benign.
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Image: the new wearable device; Copyright: Tae Hyun Kim

Biopsy alternative: 'Wearable' captures cancer cells from blood

02.04.2019

A prototype wearable device, tested in animal models, can continuously collect live cancer cells directly from a patient's blood. The device developed by a team of engineers and doctors at the University of Michigan could help doctors diagnose and treat cancer more effectively.
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Image: Radiolabeled protein lights up tumor implanted in the arm of a mouse under a PET scan; Copyright: Sridhar Nimmagadda

Imaging: Glowing tumors show cancer drugs

29.03.2019

Experimenting with mice, Johns Hopkins researchers report they have successfully used positron emission tomography (PET) scans to calculate in real time how much of an immunotherapy drug reaches a tumor and what parts of a cancer remain unaffected.
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Image: visitors at MEDICA; Copyright: Messe Düsseldorf

See, experience, learn: what's new at MEDICA 2018

02.11.2018

It's time: the world's largest medical trade fair opens its doors from 12 to 15 November. More than 5,000 international exhibitors will present their new innovative products and applications. Frums, conferences and special shows will feature exciting specialist lectures and discussions that will give you an insight into electromedicine, laboratory medicine, medical technology and diagnostics.
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Image: diagnosis of the lung; Copyright: panthermedia.net/Sergey Nivens

With modern imaging supplies: A look into the lung

01.10.2018

Thanks to various imaging supplies, it is possible to make the inside of the body accessible for diagnostics, research and treatment. The lung, one of the most important human organs for survival, is also examined in this way. In our Topic of the Month, we looked at how doctors are getting a closer look at the lung, how the procedures differ, and which ones will be available in the near future.
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Image: Small brown mole on the back of a hand; Copyright: panthermedia.net/Mario Hahn

Early detection: Tattoo signals cancer – and more

09.07.2018

People who are not ill and do not show any symptoms typically do not visit the doctor. And while most people know that preventive medical checkups for cancer, for example, are important, they still avoid them. They tend to be very hesitant because the doctor might detect a serious illness. In the future, a new type of implant could make it easier to go to a screening test.
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Personalized cancer medicine – Best possible treatment with TherapySelect

30.04.2018

Medicine is getting more and more personalized. This is particularly interesting for oncology, since a cancer is as individual as the respective patient. When choosing a therapy, both the characteristics of the tumor and the personal characteristics of the patient must be considered. To see exactly what this looks like, we visited the diagnostics company TherapySelect, based in Heidelberg.
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Image: DermaFC developed by Magnosco; Copyright: Magnosco

A startup makes melanin glow: skin cancer diagnostics with Magnosco

09.04.2018

When a skin lesion is suspected to exhibit malignant changes, it is usually promptly removed. However, not all cases require an excision of the affected tissue. The startup company Magnosco has developed a procedure that uses a laser to support the diagnosis and early detection of malignant melanoma.
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Image: Man with stethoscope and medical symbols; Copyright: panthermedia.net/everythingposs

Between austerity measures and growth pressure - Latin America's medical market

03.04.2018

A region whose states make up the world's third largest economy and which has few linguistic differences - Latin America is an attractive market for foreign companies at first glance. This also applies to the medical market. However, various factors are contributing to the fact that this market is growing only slowly in most countries.
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Image: A group of physicians is holding large colorful puzzle pieces in their hands and is putting them together; Copyright: panthermedia.net/Andriy Popov

Personalized medicine: a paradigm shift is gaining momentum

01.03.2018

Personalized medicine does not follow a "one-size-fits-all" treatment approach but emphasizes a "tailor-made" paradigm, meaning a treatment is customized to each individual person's case. For patients, this increases the chances of treatment success and means fewer side effects. While the approach originates in the field of oncology, it is now also increasingly applied to other disease patterns.
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Image: Three men in suits and a woman in a laboratory coat are standing in a laboratory; Copyright: Ministry of Economy of Mecklenburg-Hither Pomerania/Norbert Fellechner

On the trail of cancer: personalized cancer vaccine

01.03.2018

Conventional cancer treatment selection typically depends on the location of the tumor. However, this approach ignores the distinct gene mutations in the tumor of the individual patient. New cancer research approaches increasingly emphasize the concept of personalized therapy.
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Image: yellow tape measure with capsules in front of it; Copyright: panthermedia.net/Jiri Hera

Personalized cancer medicine: customized treatment

01.03.2018

Everyone is different. This statement also applies to our health. Cancer, in particular, can look and progress differently depending on the individual person. That’s why every patient ideally also needs a customized treatment that is tailored to their individual needs. But how feasible is this idea?
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Image: a container with the nutrient medium for cancer cells; Copyright: Dr. Markus Wehland

Cells in space – extraterrestrial approaches in cancer research

22.02.2018

Here on Earth, all experiments are bound by gravitation. Yet, freed from gravity's grip, tumor cells, for example, behave in an entirely different way. As part of the "Thyroid Cancer Cells in Space" project by the University of Magdeburg, smartphone-sized containers carrying poorly differentiated thyroid cancer cells are sent into space.
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MEDICA 2017: Cutting-edge, look into the future

13.11.2017

For exhibitors and visitors, MEDICA 2017 does not start until Monday. However, the trade press already gets a preview of some selected product highlights on the Sunday before the trade fair. We were there with the camera and met with some exhibitors. They gave us the opportunity to present cutting-edge products and to take a look at the medical technology of the future.
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Image: Vials in a rack; Copyright: Messe Düsseldorf

MEDICA 2017: all about laboratory medicine at the MEDICA LABMED FORUM

02.10.2017

If you are interested in laboratory medicine and come to the MEDICA 2017, you will quickly notice that Exhibition Halls 1 and 2 were demolished. A new state-of-the art hall is meant to take their place. Until then, exhibitors from the field of laboratory medicine will be showcased at their temporary new location in the lightweight hall structures 3a and 18 on the fairgrounds.
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Image: Colored sonographic image of the human heart from Doppler ultrasonography; Copyright: panthermedia.net/Belish

Imaging techniques: ultrasound, MRI, CT, catheters and other procedures to keep a healthy heart

01.09.2017

Many people are affected by heart disease today because - among other reasons- our modern unhealthy lifestyle is taking a toll on our hearts. A reliable diagnosis and treatment are crucial for patients with heart disease since all other organs depend on the pumping of our vital organ. Modern imaging techniques are a key to understanding the heart.
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Image: interferometric detection of scattered light, iSCAT; Copyright: MPL

Interface between Physics and Medicine: new interdisciplinary center

22.08.2017

Physics has always supported medical science, especially when it comes to practical implementation. Now physicists and health professionals join in collaborative research at an interdisciplinary Center in Erlangen and incorporate fundamental principles of theoretical physics in their studies of diseases.
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Image: A large medical device with a treatment couch and four movable boxes; Copyright: panthermedia.net/Thomas Hecker

Cancer: refined treatment with proton minibeams

10.07.2017

Radiation therapies are an essential component of today’s oncology because they enable the treatment of localized tumors. Yet they have one major drawback: radiation damages not just tumor cells but also healthy tissue. One solution to solve this problem could be proton minibeam therapy, which uses finely focused beams.
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Image: A flat device with a touch screen; Copyright: biolitec AG

Surgical lasers: the quest to be compact, mobile, and user-friendly

03.07.2017

Not all lasers are the same – especially in the surgical field, it all depends on what’s inside: the different operational wavelengths of laser light also affect human tissue in different ways. This is why a single laser for a variety of applications drastically simplifies the job of physicians.
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Image: A dermatology laser is used to remove a mole; Copyright: panthermedia.net/Michael Krause

Laser surgery: usability, flexibility, treatment quality

03.07.2017

The scalpel is considered the classic surgical instrument and as such, has remained unchanged for quite some time. However, today’s technology opens up a world of new possibilities for cutting tissue. Next to high-frequency electrosurgical scalpels that work with electric power, surgeons also use a variety of different lasers. They promise great usability and better treatment.
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Photochemical internalization – A new hope against bile duct cancer?

03.07.2017

Advanced bile duct tumors cannot always be removed surgically. Then, patients receive chemotherapy and a stent that corrects the narrowing of the bile duct that is caused by the tumor. Another, local therapy option is tested at the University Hospital Frankfurt: laser light is used to transport drugs into the tumor during photochemical internalization.
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Image: A women with a bald head and a headscarf, smiling, sitting on a sofa talking ot another woman; Copyright:Katharina Bia asiewic

Irreversible Electroporation – Last hope for liver cancer patients

24.04.2017

Liver cancer is the fifth most common malignant tumor in the world. The tumor can be removed through surgery or by utilizing thermal ablation techniques. If a treatment with conservative methods is no longer possible, there is an alternative: irreversible electroporation (IRE). The effectiveness of this method was now confirmed by a clinical study.
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Image: A young girl is lying in the hospital bed, behind her a nurse is adjusting a monitor; Copyright: panthermedia.net / Monkeybusiness Images

Working with children with cancer – More than just a job

02.01.2017

Our topic title "pediatric (children’s) oncology" evoked strong emotional reactions from several mothers and fathers of our staff. "This hits too close to home for me, I couldn’t write about it", or "How do people manage to deal with this?". And we are only on the sidelines; physicians, caregivers and nurses at the hospital, hospice or families at home are the ones that have the real tough job.
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Image: Three physicians during a meeting; Copyright: KiTZ/Philipp Benjamin

Children's Tumor Center: consolidated treatment under one roof

02.01.2017

Treatments for children need to be different from treatment for adults – this also applies in oncology. Having said that, children do not just need new and different treatment concepts that still necessitate research. They also require the support from their families, who need to be nearby during treatment.
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