Magazine overview -- MEDICA - World Forum for Medicine

Image: Close-up of a brain MRI scan result; Copyright: Rawpixel

Rawpixel

Brain tumor cells invade the brain as neuronal free riders

08/08/2022

Scientists at Heidelberg University Hospital, Heidelberg University and the German Cancer Research Center have discovered an elementary new spreading strategy in gioblastomas, the most aggressive of all brain tumors.
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Image: A woman waits for an EEG measurement while researcher Dr. Vukelic prepares the electrodes with gel, Copyright: Audi

Audi

Technology that responds sensitively to people

05/08/2022

How does work affect our daily lives and how does it affect our mental and physical health? How do technical solutions change people and how can devices be made more human-centric? A five-person team at the Fraunhofer Institute for Industrial Engineering IAO is investigating these issues.
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Image: Two smiling men sitting in an inner courtyard - Klaus Gerwert and Léon Beyer; Copyright: RUB/Marquard

RUB/Marquard

Sensor: early Alzheimer’s detection up to 17 years in advance

01/08/2022

The dementia disorder Alzheimer’s disease has a symptom-free course of 15 to 20 years before the first clinical symptoms emerge. Using an immuno-infrared sensor developed in Bochum, a research team is able to identify signs of Alzheimer’s disease in the blood up to 17 years before the first clinical symptoms appear.
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Image: Illustration showing how an AI-based test method works; Copyright: Ryuji Kato

Ryuji Kato

AI detects whether drugs are effective for neurodegenerative diseases

01/08/2022

A research group from Nagoya University in Japan has developed an artificial intelligence for analyzing cell images that uses machine learning to predict the therapeutic effect of drugs. Called in silico FOCUS, this new technology may aid in the discovery of therapeutic agents for neurodegenerative disorders such as Kennedy disease.
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Image: Micrograph of drying patterns of peptide solutions; Copyright: Karlsruhe Institute of Technology

Karlsruhe Institute of Technology

Peptide "fingerprint" enables earlier diagnosis of alzheimer’s disease

28/07/2022

Neurodegenerative diseases like Alzheimer’s disease or Parkinson’s disease are caused by folding errors (misfolding) in proteins or peptides, i.e. by changes in their spatial structure.
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Image: Two smiling men are standing in front of a large, box-shaped device with a glass front – Prof. Niels Voigt, Dr. Thomas Mager; Copyright: mbexc

mbexc

Unique technology platform for cellular electrophysiology and optogenetics

26/07/2022

Electrical activity is one of the most important common features of the heart and the brain. The goal of the Göttingen Cluster of Excellence "Multiscale Bioimaging: From Molecular Machines to Networks of Excitable Cells (MBExC)" is to understand the functional properties of cardiomyocytes and neurons, which form the smallest electrically active units of both organs.
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Image: Illustration of a human head an the Transcranial Magnetic Stimulation; Copyright: Alexandre Azinheira, Champalimaud Foundation.

Alexandre Azinheira, Champalimaud Foundation.

Brain stimulation as an antidepressant treatment for older adults

25/07/2022

New study from the Champalimaud Foundation’s Neuropsychiatry Unit casts doubt on long-held but controversial belief that repetitive transcranial magnetic stimulation (rTMS) may not be suitable treatment for depression in older adults.
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Image: iHandUApp on a smartphone shows medical statistical data; Copyright: INESC Brussels HUB

INESC Brussels HUB

Wearable system tracks Parkinson’s Disease symptoms remotely

22/07/2022

Parkinson’s Disease affects 10 million people worldwide and its symptoms include tremors in the fingers and hands, small handwriting, loss of smell, walking difficulties, dizziness, and others. As these symptoms worsen over time, monitoring and treating PD is crucial to preserve the patients’ autonomy and enhance their quality of life.
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Image: A virtual reality scenario in a subway: Copyright: neomento

neomento

Start-up "neomento": virtual therapy against real anxieties

21/07/2022

Berlin-based "neomento GmbH" is a developer of virtual reality scenarios for the treatment of social phobias – an umbrella term for psychiatric disorders that occur when people meet and interact with each other.
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Image: A woman works on a chip with electronic tools: Copyright: Ingebjørg Hestvik

Ingebjørg Hestvik

Getting a wireless network under the skin to talk to the brain

19/07/2022

Researchers at the Norwegian University of Science and Technology (NTNU) are working to develop solutions where the brain will be able to capture sensory impressions from a prosthesis, process them and use them to control movements, almost as if it were a normal hand — without having to imbed batteries and wires.
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Image: Doctor shows elderly patient with dementia geometric shape game; Copyright: davidpereiras

davidpereiras

Could a computer diagnose Alzheimer’s disease and dementia?

15/07/2022

Boston University researchers develop an artificial intelligence program that detects cognitive impairment accurately and efficiently from voice recordings.
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Image: A laboratory worker performs a blood test; Copyright: seventyfourimages

seventyfourimages

Dementia: Blood levels could point to early loss of neuronal connections

01/07/2022

Researchers from DZNE and Ulm University Hospital have identified a protein in the blood that may indicate the degradation of neural connections years before the onset of dementia symptoms.
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Image: A man undergoes an X-ray examination, a doctor looks at the result of the bone density scan; Copyright: Getty

Getty

Quick, easy scan can reveal late-life dementia risk

30/06/2022

A long-term study has shown a common bone density scan can also show calcified plaque build-up in the abdominal aorta - revealing if someone is at increased risk of developing dementia.
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Image: A girl in a denim overall blows soap bubbles in a field in the summer: Copyright: Simol1407

Simol1407

Smart jumpsuit tracks infants’ motor development

24/06/2022

New wearable technology creates new possibilities for assessing the neurological development of young children. Early motor assessment is essential for supporting the early detection of neurodevelopmental problems and their therapeutic interventions.
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Image: A nurse takes care of a person with parkinson; Copyright: bialasiewicz

bialasiewicz

Prospect of blood test for Parkinson’s disease for the first time

24/06/2022

A research team at the Faculty of Medicine at Kiel University has developed a method that reliably detects protein changes in blood that are typical of Parkinson's disease.
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Image: Man during a neurological examination ; Copyright: engagestock

engagestock

Protein changes in the liquor indicate inflammatory processes in the brain

23/06/2022

Alzheimer's, Parkinson's and other neurodegenerative diseases are associated with inflammatory processes in the brain. German researchers have succeeded in identifying a group of proteins in the cerebrospinal fluid that could provide information about such inflammatory processes.
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Image: Radiologists look at brain scans ; Copyright: imagesourcecurated

imagesourcecurated

Single brain scan can diagnose Alzheimer’s disease

22/06/2022

A single MRI scan of the brain could be enough to diagnose Alzheimer’s disease, according to new research by Imperial College London.
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Image: Blue-and-violet image of a blood clot; Copyright: Empa

Empa

Personalized medicine: Treatment of acute stroke

14/06/2022

A blood clot in the brain that blocks the supply of oxygen can cause an acute stroke. In this case, every minute counts. A team from Empa, the University Hospital in Geneva and the Hirslanden Clinic is currently developing a diagnostic procedure that can be used to start a tailored therapy in a timely manner, as they write in Scientific Reports.
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Image: Neurologist doctor analyzing nervous system with EEG headset scanning in a woman; Copyright: DC_Studio

DC_Studio

Nerve stimulation promotes resolution of inflammation

10/06/2022

The nervous system is known to communicate with the immune system and regulate inflammation in the body. Researchers at Karolinska Institutet in Sweden now show how electrical activation of a specific nerve can promote healing in acute inflammation. The finding, which is published in the journal PNAS, opens new ways to accelerate resolution of inflammation.
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Image: Close-up of a newborn baby; Copyright: twenty20photos

twenty20photos

Genetic testing for neonatal epilepsy allows babies to go home sooner

09/06/2022

Genetic testing results in lower length of stay in the neonatal intensive care unit (NICU) for infants with epilepsy, according to a study published in the journal Pediatric Neurology.
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Image: Side view of a child's head with a cohclea implant ; Copyright: Shutterstock

Shutterstock

Deaf children with learning delays benefit from cochlear implants more than hearing aids

30/05/2022

Keck Medicine of USC study demonstrates the need for early cochlear implant use for deaf children, regardless of developmental impairments.
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Image: A man is given general anesthesia; Copyright: nd3000

nd3000

Anesthesia: rhythmical deep sleep

26/05/2022

Researchers at the German Primate Center study influence of anesthetics on brain functions.
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Image: Locus coeruleus as observed in a 7T MRI scanner ; Copyright: University of Cambridge

University of Cambridge

Brain scanners: Hope for treating cognitive symptoms in Parkinson’s

23/05/2022

Ultra-powerful 7T MRI scanners could be used to help identify those patients with Parkinson’s disease and similar conditions most likely to benefit from new treatments for previously-untreatable symptoms, say scientists.
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Image: A woman with glasses and white hair is solving some tasks on a sheet of paper; Copyright: PantherMedia/microgen

PantherMedia/happysuthida

Dementia: "We want to achieve earlier diagnosis for more people"

29/03/2022

As we get older, we tend to become more forgetful, sometimes strange or even confused and overwhelmed by everyday life. But is it always just the age? With an increasing lifespan, the possibility to suffer from a cognitive disease at one point is also increasing. The majority of cognitive diseases is never diagnosed.
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Image: Cartoon for the Konectom App; Copyright: Phil Hubbe/ZKN

Phil Hubbe/ZKN

Konectom: App supports self-management of Multiple Sclerosis

08/02/2022

Multiple sclerosis (MS) is a disease of the central nervous systems that requires regular checkups with the neurologist every three months. However, an exacerbation of MS, also known as a flare-up, can occur between these appointments. The Konectom smartphone app aims to close this diagnostic gap.
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Image: A signal receiver and a transmitter of a Cochlear implant on the palm of a person; Copyright: PantherMedia/npudov

PantherMedia/npudov

Implants: When technology makes sense – quite literally

01/12/2021

Disease, injury, or a condition you were born with – reasons why some people must live without one or several of their five senses. Fortunately, there are many modern sensory aids that help replace one sense with another, which is especially the case when it comes to vision and hearing. Given technology's advancements, can artificial or biological implants someday soon be a viable alternative?
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Image: Illustration of the way an optical Cochlear implant functions; Copyright: UMG

UMG

Cochlear implants: Using light to improve hearing

01/12/2021

Cochlear implants are devices that partially restore hearing in wearers. Unfortunately, the signal transmission from the implant to the auditory nerve is still rather basic, thus limiting the sound quality. Future implants could be more accurate in this setting by using light versus electrical pulses to stimulate nerve cells in the ear.
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Image: A female physiotherapist is helping a woman during an exercise with a therapeutic rubber band; Copyright: PantherMedia/photographee.eu

PantherMedia/photographee.eu

Stroke rehabilitation: regaining arm movement with nerve stimulation

09/08/2021

Stroke rehabilitation exercises are essential to regain mobility and strength in the body. Each patient recovers lost skills and function differently. A recent study has now examined how vagus nerve stimulation with electrical impulses during stroke rehab could improve arm mobility.
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Image: A woman sitting in front of a device for an eye examination; Copyright: PantherMedia/Med_Photo_Studio

PantherMedia/Med_Photo_Studio

Alzheimer's disease: early detection using an eye exam

22/03/2021

Alzheimer's disease is still incurable, but if detected early enough, countermeasures can improve treatment and slow the progression. Unfortunately, there is still no reliable early detection test at this juncture. This might soon change thanks to a non-invasive spectroscopy of the retina.
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Image: a woman wearing a wearable EEG that looks like a headband; Copyright: Evercot AI GmbH

Evercot AI GmbH

Good connection: AI and EEG work hand in hand

17/02/2021

Artificial intelligences (AI) are able to help medical professionals detect diseases. This is based on medical data records from which the AI can draw conclusions about diseases. These conclusions are most accurate when the extraction of the data sets is directly linked to the processing.
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Image: A young woman is wearing a flat device made from printed electronics on her forehead; Copyright: Universität Oldenburg/Abteilung Neuropsychologie

Universität Oldenburg/Abteilung Neuropsychologie

Wearable EEG: A comfortable way to record brain activity

09/11/2020

An electroencephalogram (EEG) is a test that is used in cognitive research or to diagnose conditions such as epilepsy and sleep disorders. EEG electrode caps are somewhat difficult to wear, which is why they are only used in laboratories. One viable alternative are measuring devices made of printed electronics. They are more comfortable to wear and allow users to continue their daily activities.
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Image: Physician checks function of an arm prosthesis; Copyright: PantherMedia/belahoche

PantherMedia/belahoche

Bionic prosthesis: easy to put on, intuitive to use

22/09/2020

Patients who receive a prosthesis after the amputation of a limb often have to train for weeks or months until they can control the technology and use it in everyday life without problems. At the Medical University of Vienna, the world's first bionic prosthesis has now been developed that has a closed control loop and enables immediate, intuitive use.
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Image: Nurse checking surveillance monitor at the bedside and writing down patient data on a clipboard; Copyright: PantherMedia/Kzenon

PantherMedia/Kzenon

Big Data: early warning system for the ICU

03/08/2020

Patient monitoring systems in the ICU sound up to 700 alarms on average per patient per day, which boils down to one alarm every two minutes. An excessive number of them are false alarms. This generates vast amounts of data, which can make it difficult for doctors and nurses to identify the most critical alarms to manage. It also has a negative effect on the treatment of intensive care patients.
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Image: Female physician is looking a CT images of the brain next to a patient in an ICU bed; Copyright: PantherMedia/sudok1

Comprehensive stroke care: faster, closer, better

02/06/2020

"Time is brain!" – a fundamental rule in stroke care because time is of the essence when brain regions are undersupplied with oxygen and glucose. If circulation is not restored quickly, brain damage can be permanent. However, the key point here is not just to "be fast", but also to "use the time to treat stroke effectively".
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Image: An older man lies on the ground and presses a hand to his head, his wife kneels next to him and calls an ambulance; Copyright: PantherMedia/AndrewLozovyi

PantherMedia/AndrewLozovyi

Stroke care: When every minute counts

02/06/2020

Stroke can affect anyone – older as well as younger people. The minutes after the stroke determine whether disability or death is the result. Only if acute care, inpatient treatment and rehabilitation are carried out in a targeted and effective manner, the chances are greater that only minor damage remains or that impairments even recede.
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Image: Man sitting next to an older woman wearing vr glasses on a couch; Copyright: panthermedia.net/draoscondreaw

panthermedia.net/draoscondreaw

Sensor-Based Smart Glove Enables Parkinson's Diagnosis

25/02/2020

Neurological disorders like Parkinson's are often diagnosed once the disease has already progressed to a later stage. The VAFES project was initiated to facilitate an early detection. Sensor technology and VR are used in the creation of a playful test system.
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Image: Wojcech Radomski; Copyright: StethoMe

Telemedicine: easy breathing with AI for respiratory tract

01/10/2019

Pneumonia, COPD or cystic fibrosis – people with such lung diseases have to consult their doctor regularly. Little children have to undergo certain measurements by the doctor, too. In order to save people`s need to visit a doctor, telemedicine offers many ways to do examinations at home.
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Image: DLIR image of the aorta; Copyright: GE Healthcare

Deep Learning Image Reconstruction – what AI looks like in clinical routine

02/09/2019

Artificial intelligence is no longer a dream of the future in medicine. Many studies and initial application examples show that it sometimes achieves better results than human physicians. At Jena University Hospital, the work with AI is already lived practice. It is the first institution in the world to use algorithms in radiological routine to reconstruct CT images.
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Image: CT image of the lungs with AI-supported automatic highlighting, quantification and measurement of anatomy and deviations; Copyright: Klinikum Nürnberg

AI in radiology: reliable partner for diagnosing CT images

02/09/2019

More patients, more examinations, more CT images – in radiology there is too much work for too few physicians. CT scans are evaluated in the shortest possible time, which leads to anomalies being overlooked. Artificial intelligence, on the other hand, works with constant speed and performance, which is why radiological routine increasingly relies on its support.
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Image: Robot points with his finger at CT images of the brain, in the background a CT device; Copyright: panthermedia.net/phonlamai

Man vs. machine – the benefits of AI in imaging

02/09/2019

Radiology is a field that produces large volumes of data, which can no longer be managed without the help of intelligent systems. This is especially true when it comes to the interpretation of medical images. While this takes physicians years of training and experience, several hours of work and the highest level of concentration, AI only requires a few seconds to accomplish the same task.
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Image: Robot looks at huge amount of CT images of the brain; Copyright: panthermedia.net/phonlamai

AI in imaging: how machines manage our Big Data

02/09/2019

In modern medicine, especially in the field of imaging, huge amounts of data are produced – so much that radiologists can hardly keep up with diagnosing the images. Artificial Intelligence could be the solution to this problem. But how exactly can it help in this task? How can man and machine work together? And what else will be possible in the future with the support of intelligent systems?
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Image: Marathon runner; Copyright: panthermedia.net/adamgregor

Sports medicine – keep moving to stay healthy

01/07/2019

Physical activity plays a big role in today's society. Whether you are an amateur or professional athlete – incorporating exercise into your life positively impacts your mental and physical health. Ideally, sport should be fun, pressure-free and not overburden you. But can you measure individual performance and align it with sports?
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Image: High jump of an athlete; Copyright: panthermedia.net/Moodbaord

Training and rehabilitation: fit thanks to hover technology

01/07/2019

Amateur and professional athletes are susceptible to sports injuries, balance disorders or deficits in motor function and posture. Prevention and the right training can help avoid these incidents, while targeted therapy can support a return to sports after an injury.
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Image: Team Capsix with KUKA robot arm and body model; Copyright: Capsix Robotics, Lyon

Capsix Robotics, Lyon

Healthy Living thanks to robotics – KUKA Innovation Award 2019

24/06/2019

Improving technology transfer from research to industry and driving robotics development - that's the idea behind the KUKA Innovation Award. This year’s topic is "Healthy Living". Applicants from around the world were tasked with creating a robot application for healthcare settings. Now, the finalists, who will showcase their innovations at the MEDICA 2019 trade fair have been selected.
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Image: Female surgeon in scrubs is standing in an MRI control room and looks at screens; Copyright: Medtronic

Medtronic

VISUALASE: epilepsy surgery with the laser catheter

11/06/2019

Epilepsy patients are currently treated with either medication or surgical options. The aim is to remove the distinct regions of the brain that cause epileptic seizures. Laser ablation for epilepsy is a new, catheter-based surgical procedure that is now also available in Europe, preventing patients from having to undergo open brain surgery.
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Image: Boy uses robot arm in front of a monitor with computer game, next to it stands the therapist; Copyright: Helios Klinik Hattingen

Rehab with a robot – robot-assisted therapy in neurology

03/06/2019

It takes consistent repetitions if rehab patients want to relearn skills after surviving a stroke. This requires extreme effort. The industrial sector uses robots to perform repetitive tasks or handle jobs that require strength. What has been a fixture in factories for decades is now also making its way into rehabilitation facilities.
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Image: Woman uses robot arm to grab something on the table; Copyright: RWTH Aachen/RPE & inRehaRob

Of exoskeletons and service robots – the future of rehabilitation

03/06/2019

For most people, enjoying a good quality of life means having the ability to move freely, safely and independently. Intensive and costly rehabilitation is needed if this is no longer an option after a stroke for example. We are introducing some projects that deliver innovative robotic solutions.
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Image: triangular table at which three patients do various robotic rehabilitation exercises; Copyright: Hocoma, Switzerland

Walking is an issue of mind over matter – how robots assist rehabilitation

03/06/2019

Humans are living longer than ever but still want to continue to live independently as they age. Meanwhile, our motor and cognitive abilities decline as we age, sometimes as the effects of a stroke. The number of people in need of long-term care is growing at breakneck speed. At the same time, fewer and fewer young people choose stressful careers as caregivers.
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Image: Boy with robotic gait trainer on treadmill; Copyright: panthermedia.net/olesiabilkei

Robotics – rehab with motors and sensors

03/06/2019

They work with power, precision and tirelessly. This makes robots an ideal instrument for rehabilitation. In gait or motor training, movement sequences must be repeated thousands of times so that they can be learnt anew. What tires the patient and costs the therapist's time can easily be managed by robot-assisted systems. Learn more about the possibilities of robotics in rehabilitation.
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Image: Man on a treatment table under a radiation therapy device; Copyright: panthermedia.net/adriaticphoto

panthermedia.net/adriaticphoto

Cardiac arrhythmia: treatment in the linear accelerator

08/04/2019

Cardiac arrhythmia is a group of conditions where nerve cells trigger uncontrolled contractions of the heart muscle. They are treated with either medicine or catheter ablation of the tissue. In an interdisciplinary collaboration, cardiologists and radiotherapists took a different approach and used high-precision radiation therapy to treat a patient for whom the other options proved unfeasible.
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Image: close-up of a woman lying in an MRI device; Copyright: panthermedia.net/Craig Robinson

Brain mapping: preoperative planning with functional MRI

01/04/2019

A surgery already begins before the patient is lying on the operating table – namely with the planning. For example, if brain surgery is imminent, the brain must first be mapped. This makes the activity level of certain brain areas visible. Functional magnetic resonance imaging makes this possible.
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Image: Patient during an fMRI examination; Copyright: panthermedia.net/Chris De Silver

Functional imaging: what makes the brain tick?

01/04/2019

Our brain is the command center of our body. This is where all information and impressions are collected and converted into responses and movements. Modern imaging techniques offer physicians and researchers unique insights into the actions of the human central nervous system. The functional imaging technique allows them to watch our brain in action.
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Image: CT scan open; Copyright: panthermedia.net/SimpleFoto

Functional imaging: a look at the command center

01/04/2019

All information from our body and the environment converges in our brain and is transformed into reactions in milliseconds. It is essential for medicine and research to know what our switching centre looks like. Functional methods are used to observe it more closely during work.
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Image: Man during CT examination; Copyright: panthermedia.nt/Romaset

Stroke: 4D brain perfusion accelerates treatment

01/04/2019

In an ischaemic stroke, rapid treatment is essential. In this moment good imaging data is particularly important to enable doctors to make the best possible decision for therapy. Modern CT scanners are increasingly being used to assess stroke patients because they can show the blood flow to the brain over time.
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