Public Health & Associations -- MEDICA Trade Fair

Image: Laboratory technician holds a Petri dish; Copyright: Fraunhofer ITEM

Fraunhofer launches a pioneering collaboration with iCAIR project

20/10/2017

Bacteria keep developing new resistances to antibiotics. There is a desperate need for new medications. The biggest hurdle in developing these new medications is getting them from the laboratory and into clinical trials. iCAIR will use selected lighthouse projects to establish and demonstrate its position as an expert preclinical development platform for new anti-infective drugs.
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Image: Clipboard with restless-legs-syndrome written over it; Copyright: panthermedia.net/Boris Zerwann

Restless legs syndrome study identifies 13 new genetic risk variants

18/10/2017

A new study into the genetics underlying restless legs syndrome has identified 13 previously-unknown genetic risk variants, while helping inform potential new treatment options for the condition.
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Image: A healthy liver cell and a HCV-infected liver cell in comparison; Copyright: Marianne Doré Hansen & Marit Anthonsen

How hepatitis C hides in the body

17/10/2017

The Hepatitis C (HCV) virus is a sly enemy to have in one’s body. Not only does it manage to make itself invisible to the immune system by breaking down communication between the immune cells, it also builds secret virus "factories" that quickly go into mass production.
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Image: A volunteer receives an injection in the PREVAIL Ebola vaccine clinical trial; Copyright: PREVAIL

Experimental Ebola vaccines elicit year-long immune response

16/10/2017

Results from a large randomized, placebo-controlled clinical trial in Liberia show that two candidate Ebola vaccines pose no major safety concerns and can elicit immune responses by one month after initial vaccination that last for at least one year.
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Image: tools for blood testing; Copyright: panthermedia.net/gisne

Blood samples may provide patient radiosensitivity answers

13/10/2017

How much radiation or chemotherapy can a certain person handle? With help from blood or tissue testing, it may be possible to answer this question in advance, which in turn could improve treatment, as research at Sahlgrenska Academy shows.
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Image: young woman sleeping; Copyright: panthermedia.net/pressmaster

New insights into how sleep helps the brain to reorganise itself

13/10/2017

A study has given new insights into how sleep contributes to brain plasticity – the ability for our brain to change and reorganise itself – and could pave the way for new ways to help people with learning and memory disorders.
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Image: illustration of a cancer cell; Copyright: panthermedia.net/Sebastian Kaulitzki

Stanford-led study uncovers mutation that supercharges tumor-suppressor

12/10/2017

Cancer researchers have long hailed p53, a tumor-suppressor protein, for its ability to keep unruly cells from forming tumors. But for such a highly studied protein, p53 has hidden its tactics well.
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Image: proteins that stand guard at transmembrane channels in the walls of nerve cells; Copyright: Rice University/UTHEALTH

Nerve cells' gatekeepers take many forms

11/10/2017

Rice, UTHealth researchers use light-sensitive molecules to track proteins critical to cell signaling.
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Image: woman holding a pink ribbon to her chest; Copyright: panthermedia.net/tomas_anderson

Genetic targets to chemo-resistant breast cancer identified

10/10/2017

Research led by Dr. Carlos Arteaga, Director of the Harold C. Simmons Comprehensive Cancer Center, has identified potential targets for treatment of triple negative breast cancer, the most aggressive form of breast cancer.
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Image: new born baby with pacifier on a pillow; Copyright: panthermredia.net/hansenn

How the lungs of premature babies can undergo damage

09/10/2017

Premature babies that need ventilation to support their breathing often suffer from a condition known as bronchopulmonary dysplasia. Researchers at the Helmholtz Zentrum München, partner in the German Center for Lung Research (DZL), have now discovered a molecular mechanism that plays a key role in the development of the disease.
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Image: microscope image of fluorescent cancer cells; Copyright: panthermedia.net/vshivkova

New approaches in targeted cancer therapy

06/10/2017

In a large-scale testing procedure, scientists from Cologne University Hospital have explored the effects of more than 1,500 substances on different kinds of cancer cells. The results from this study are a fundamental prerequisite for the development of new therapies for NMC, an aggressive cancer which is often lethal.
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Image: stacked pills; Copyright: panthermedia.net/Dieter Beselt

Even open-label placebos work – if they are explained

06/10/2017

For some medical complaints, open-label placebos work just as well as deceptive ones. As psychologists from the University of Basel and Harvard Medical School report in the journal 'Pain', the accompanying rationale plays an important role when administering a placebo.
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Photo: A hand with the Gripfroce Box; Copyright: TU München

Determining motor deficits more precisely following a stroke

03/10/2017

After a stroke, many people are unable to successfully perform basic hand movements in everyday life. The reason are symptoms of hemiparesis resulting from damage to the brain. These very frequently affect fine motor skills. A team from the Technical University of Munich (TUM) is now paving the way to better diagnosis and more targeted therapy.
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Image: image of a transparent human upper body with blue lungs; Copyright: panthermedia.net/iLexx

COPD action plan shortens duration of flare-ups and reduces hospital admissions

03/10/2017

The University of Twente carried out the first study worldwide that shows patients with COPD (lung disease caused by smoking) and other illnesses (heart disease, diabetes, anxiety and depression) have better outcomes if they follow a self-management programme with a customised action plan. Anke Lenferink of UT recently obtained a doctoral degree on this subject.
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Image: blood cells in a blood vessel; Copyright: panthermedia.net/Eraxion

Fresh blood for damaged tissues via alginate hydrogels

29/09/2017

Biomaterial-mediated delivery of blood vessel growth factors could be used as a therapeutic strategy to treat peripheral vascular disease.
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Image: transparent human head, showing the brain and firing synapses; Copyright: panthermedia.net/the_lightwriter

Researchers of TU Dresden have pioneered a brain-network bio-inspired algorithm to predict new therapeutic targets of approved drugs

29/09/2017

An international team of scientists led by Dr. Carlo Vittorio Cannistraci, Junior Group Leader of the Biomedical Cybernetics lab at the BIOTEChnology Center TU Dresden, has developed a powerful computational method that can exploit the principles of brain-network self-organization.
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Image: shaking hands of an elderly woman holding a glass of water; Copyright: panthermedia.net/Astrid08

Researchers hopeful they can improve techniques for joint defect treatment

28/09/2017

Different surface topographies and materials provide interesting ways to study cell behaviour and potentially provide novel solutions for treating joint defects. Tissue engineering methods that simulate native cartilage could prove useful to create cartilage implants in the laboratory, according to a doctoral dissertation from Umeå University.
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Image: shaking hands of an elderly woman holding a glass of water; Copyright: panthermedia.net/Astrid08

Diabetes medicine reduces Parkinson's risk

28/09/2017

A Norwegian study shows that the taking of diabetes medicine reduces the risk of getting Parkinson's disease.
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Image: transparent human body with intestinal system highlighted in orange; Copyright: panthermedia.net/sciencepics

Promising modification of the intestinal flora in colon cancer

27/09/2017

Living lactic acid bacteria, probiotics, can change the intestinal flora of patients with cancer of the colon. These are the findings of a study published in the journal BMJ Open Gastroenterology.
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Image: woman holding a hand to her throat, which is marked red; Copyright: panthermedia.net/vonschonertagen

New treatment for chronic throat irritation and globus sensation in the gullet

26/09/2017

Chronic throat irritation, a permanent globus sensation, a sore or dry sensation in the throat are common symptoms, which are often trivialised and wrongly attributed to gastro-oesophageal reflux disease. However, these are also the characteristic symptoms of patients suffering from displaced gastric mucosa in the oesophagus (ectopic mucosa).
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Image: cross section through a healthy bone above cross section of a bone with osteoporosis ; Copyright: panthermedia.net/Roberto_Biasini

Researchers describe mechanism that underlies age-associated bone loss

25/09/2017

This knowledge can provide targets in the search for novel bone-loss therapeutics to treat osteoporosis.
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Image: model of a human brain with luminous areas; Copyright: panthermedia.net/pixologic

Drugs in disguise heal the brain

22/09/2017

The treatment of brain diseases is on the verge of a breakthrough. Researchers from Aalborg University are developing a new method that 'smuggles' medicine past the brain's defense systems, giving hope that diseases such as Alzheimer's can one day be cured.
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Image: image of how Taxanes induce tripolar instead of normal bipolar cell division; Copyright: Munich University Hospital

Cancer drug stimulates tripolar mode of mitosis

21/09/2017

Taxanes inhibit cell division and make cancer cells sensitive to radiation therapy. A current study has investigated the underlying mechanisms of this action – and which biomarkers may be useful for predicting the success of therapy.
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Image: Doctor is holding a patient's hand; Copyright: panthermedia.net/luckybusiness

"If silence is dangerous" – International Patient Safety Day 2017

15/09/2017

In this year, the 3rd International Patient Safety Day takes place under the topic „If silence is dangerous“. On Sunday, 17th September 2017, and during the following week, all interested stakeholders in the health care system can inform themselves about the subject of patient safety and discuss it with others.
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Image: yellow warning sign with the word

Asthma drug from the garden center

15/09/2017

The coralberry could offer new hope for asthmatics: researchers at the University of Bonn have extracted a new kind of active pharmaceutical ingredient from its leaves to combat this widespread respiratory disease.
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Image: human body surrounded by immune cells and blood cells; Copyright: panthermedia.net/lightsource

Thorough analysis reveals immune system dynamics after immunotherapy

13/09/2017

By combining new system-biological analyses and advanced data analysis, researchers at Karolinska Institutet have been able to monitor the maturation process of the immune system of leukaemia patients who have undergone stem cell transplantation.
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Image: a human skeleton, several joints highlighted red; Copyright: panthermedia.net/eraxion

New osteoporosis treatment uses traditional Chinese herb to prevent bone loss

12/09/2017

An herb widely used in traditional Chinese medicine might hold the key to a new osteoporosis therapy that could prevent bone loss without causing side effects.
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Image: venes and arteries; Copyright: panthermedia.net/Spectral

How new blood vessels sprout

11/09/2017

IBS biologists discovered a key regulator of normal as well as pathological formation of new blood vessels.
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Image: Diagram of the research results; Copyright: Osaka University

New drug targets for a rare kidney and liver disease

07/09/2017

In a joint international study, researchers from Osaka University have partnered with research groups from the United States and Spain to uncover how mutations in a single gene called PKHD1 lead to symptoms associated with a rare kidney and liver disease, ARPKD (autosomal recessive polycystic kidney disease).
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Image: female doctor talks with a man about his research results displayed on a computer screen; Copyright: panthermedia.net/imagepointfr

Recurrence of prostate cancer could be reduced thanks to exciting new discovery

06/09/2017

Ground breaking research could reduce the recurrence of prostate cancer in males, a new study in the journal Nature Communications reports.
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Image: different brown algae; Copyright: panthermedia.net/photographieundmehr

Treating arthritis with algae

06/09/2017

Researchers at ETH Zurich, Empa and the Norwegian research institute SINTEF are pursuing a new approach to treating arthritis. This is based on a polysaccharide, a long-chain sugar molecule, originating from brown algae.
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Image: three pill boxes with different coloured pills; Copyright: panthermedia.net/garyphoto

Mayo Clinic researchers review the clinical potential of senolytic drugs on aging

05/09/2017

Researchers are moving closer to realizing the clinical potential of drugs that have previously been shown to support healthy aging in animals.
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Image: red and white blood cells; Copyright: panthermedia.net/ezumeimages

New insights into the world of trypanosomes

29/08/2017

Such detailed images of the pathogen that causes sleeping sickness inside a host are unique so far: They illustrate the manifold ways in which the parasites move inside a tsetse fly. A research team from the University of Würzburg's Biocenter has presented the images.
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Image: fish oil pills; Copyright: panthermedia.net/outline2015

Understanding how omega-3 dampens inflammatory reactions

29/08/2017

Omega-3 fatty acids, which we primarily get through eating fatty fish, have long been thought to be good for our health. Many dietary studies have suggested that high intake is associated with a reduced risk of various disorders. Clinical trials have also shown beneficial anti-inflammatory effects in patients taking omega-3 supplements.
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Image: tablet with the diagnosis

Inadequate recognition and treatment of infants with bacterial meningitis could lead to tragedies, warn experts

28/08/2017

Research has shown that bacterial meningitis in infants may not be being diagnosed or acted on quickly enough by medical professionals.
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Image: boy holding up a asthma inhaler; Copyright: panthermedia.net/wavebreakmedia

Study by Aston University and Birmingham Children's Hospital shows complex relationship between weight and asthma

28/08/2017

Researchers at Aston University and clinicians at Birmingham Children's Hospital are exploring how children living with asthma can be supported to maintain a healthy weight.
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Image: many different pills lying on the table; Copyright: Swiss Institute of Bioinformatics

From cancer evolution to personalized therapies

24/08/2017

Being able to predict the resistance or sensitivity of a tumour cell to a drug is a key success-factor of cancer precision therapy. But such a prediction is made difficult by the fact that genetic alterations in tumours change dynamically over time and are often interdependent, following a pattern that is poorly understood.
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Image: a box with different pills; Copyright: panthermedia.net/duskbabe

Newly discovered pathway for pain processing could lead to new treatments

24/08/2017

The discovery of a new biological pathway involved in pain processing offers hope of using existing cancer drugs to replace the use of opioids in chronic pain treatment, according to scientists at McGill University.
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Image: illustration of co‐expression networks; Copyright: KTH Royal Institute of Technology

Study offers new targets for drugs to treat fatty liver disease and liver cancer

23/08/2017

There may be no silver bullet for treating liver cancer or fatty liver disease, but knowing the right targets will help science develop the most effective treatments. Researchers in Sweden have just identified a number of drug targets that can be used in the development of new efficient treatment strategies with minimum side effects.
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Image: model of a man holding a shield and fighting against illustrated pathogens; Copyright: panthermedia.net/Andreus

Immune system can be modulated by targeted manipulation of cell metabolism

22/08/2017

In its attempt to fight a serious bacterial infection, caused by listeria, for example, the immune system can become so over-activated that the resulting inflammatory response and its consequences can quickly lead to death.
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Image: Empa’s multicellular model, which is mimicking the placental barrier: a core of connective tissue cells, surrounded by trophoblast cells; Copyright: Empa

Medication for the unborn baby

21/08/2017

An Empa team has succeeded in developing a new three-dimensional cell model of the human placental barrier. The "model organ" can quickly and reliably deliver new information on the intake of substances, such as nano-particles, by the placental barrier and on any possible toxic effects for the unborn child.
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Image: transparent brain with a tumor, highlighted in orange; Copyright: panthermedia.net/Sebastian Kaulitzki

Researchers map brain tumour cells’ adaptation to oxygen deprivation

18/08/2017

The most aggressive variant of brain tumour – glioblastoma – has an average survival rate of 15 months. There is therefore an urgent need for new treatment strategies for this group of patients. A research team from Lund University in Sweden has now identified new factors which may affect the tumour cells’ ability to resist treatment.
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Image: chalk board with sketch of sugar molecule formula; Copyright: panthermedia.net/Boris Zerwann

Cancer detection with sugar molecules

16/08/2017

Scientists from the University of Würzburg have synthesized a complex sugar molecule which specifically binds to the tumor protein Galectin-1. This could help to recognize tumors at an early stage and to combat them in a targeted manner
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Image: hand and blood sugar measuring device; Copyright: panthermedia.net/gisne

Transforming skin cells to insulin

14/08/2017

Researchers at the University of Bergen have transformed skin puncture cells from diabetes patients into insulin producing cells, using stem cell techniques. The researchers' aim is to transplant these cells under the skin of people with diabetes.
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Image: microscopic view of salmonella; Copyright: HZI/Manfred Rohde

Researchers discover Achilles' heel of bacteria

10/08/2017

Salmonellae are particularly resistant to antibiotics since they possess not only one, but two membranes that protect them from harmful substances. This makes them members of the so-called Gram-negative bacteria. Since Salmonella infections are becoming increasingly difficult to treat with antibiotics, researchers are looking for alternative agents to control these pathogens.
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Image: x-ray of the kidneys; Copyright: panthermedia.net/Sebastian Kaulitzki

Drug therapy from lethal bacteria could reduce kidney transplant rejection

09/08/2017

An experimental treatment derived from a potentially deadly microorganism may provide lifesaving help for kidney transplant patients, according to an international study led by investigators at Cedars-Sinai.
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Image: Girl on a laptop with Google search on screen, holding a paper in the other hand; Copyright: panthermedia.net/diego.cervo

Researchers: Too much information can be a good thing

08/08/2017

In the world of health care, the phrase "too much information" – or TMI – can be a serious problem. If you Google "How to prevent cancer," for example, you will find list after list of websites claiming to have the winning strategy, with some plans presenting 20-30 steps.
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Image: Sample of lung fibrosis; Copyright: Helmholtz Zentrum München

Cell aging in lung epithelial cells

08/08/2017

Pulmonary fibrosis can possibly be attributed to a kind of cellular aging process, which is called senescence. This has been shown by researchers from the Helmholtz Zentrum München, partner in the German Center for Lung Research (DZL). As they report in the European Respiratory Journal, they have already successfully counteracted this mechanism in the cell culture with the help of drugs.
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Image: A network map of coloured dots; Copyright: Jeff Leinert, NHGRI

Social interaction affects cancer patients' response to treatment

27/07/2017

How well cancer patients fared after chemotherapy was affected by their social interaction with other patients during treatment, according to a new study by researchers at the National Human Genome Research Institute (NHGRI), part of the National Institutes of Health, and the University of Oxford in the United Kingdom.
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