Public Health & Associations -- MEDICA Trade Fair

Image: image of how Taxanes induce tripolar instead of normal bipolar cell division; Copyright: Munich University Hospital

Cancer drug stimulates tripolar mode of mitosis

21/09/2017

Taxanes inhibit cell division and make cancer cells sensitive to radiation therapy. A current study has investigated the underlying mechanisms of this action – and which biomarkers may be useful for predicting the success of therapy.
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Image: Doctor is holding a patient's hand; Copyright: panthermedia.net/luckybusiness

"If silence is dangerous" – International Patient Safety Day 2017

15/09/2017

In this year, the 3rd International Patient Safety Day takes place under the topic „If silence is dangerous“. On Sunday, 17th September 2017, and during the following week, all interested stakeholders in the health care system can inform themselves about the subject of patient safety and discuss it with others.
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Image: yellow warning sign with the word

Asthma drug from the garden center

15/09/2017

The coralberry could offer new hope for asthmatics: researchers at the University of Bonn have extracted a new kind of active pharmaceutical ingredient from its leaves to combat this widespread respiratory disease.
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Image: human body surrounded by immune cells and blood cells; Copyright: panthermedia.net/lightsource

Thorough analysis reveals immune system dynamics after immunotherapy

13/09/2017

By combining new system-biological analyses and advanced data analysis, researchers at Karolinska Institutet have been able to monitor the maturation process of the immune system of leukaemia patients who have undergone stem cell transplantation.
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Image: a human skeleton, several joints highlighted red; Copyright: panthermedia.net/eraxion

New osteoporosis treatment uses traditional Chinese herb to prevent bone loss

12/09/2017

An herb widely used in traditional Chinese medicine might hold the key to a new osteoporosis therapy that could prevent bone loss without causing side effects.
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Image: venes and arteries; Copyright: panthermedia.net/Spectral

How new blood vessels sprout

11/09/2017

IBS biologists discovered a key regulator of normal as well as pathological formation of new blood vessels.
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Image: Diagram of the research results; Copyright: Osaka University

New drug targets for a rare kidney and liver disease

07/09/2017

In a joint international study, researchers from Osaka University have partnered with research groups from the United States and Spain to uncover how mutations in a single gene called PKHD1 lead to symptoms associated with a rare kidney and liver disease, ARPKD (autosomal recessive polycystic kidney disease).
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Image: different brown algae; Copyright: panthermedia.net/photographieundmehr

Treating arthritis with algae

06/09/2017

Researchers at ETH Zurich, Empa and the Norwegian research institute SINTEF are pursuing a new approach to treating arthritis. This is based on a polysaccharide, a long-chain sugar molecule, originating from brown algae.
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Image: female doctor talks with a man about his research results displayed on a computer screen; Copyright: panthermedia.net/imagepointfr

Recurrence of prostate cancer could be reduced thanks to exciting new discovery

06/09/2017

Ground breaking research could reduce the recurrence of prostate cancer in males, a new study in the journal Nature Communications reports.
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Image: three pill boxes with different coloured pills; Copyright: panthermedia.net/garyphoto

Mayo Clinic researchers review the clinical potential of senolytic drugs on aging

05/09/2017

Researchers are moving closer to realizing the clinical potential of drugs that have previously been shown to support healthy aging in animals.
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Image: red and white blood cells; Copyright: panthermedia.net/ezumeimages

New insights into the world of trypanosomes

29/08/2017

Such detailed images of the pathogen that causes sleeping sickness inside a host are unique so far: They illustrate the manifold ways in which the parasites move inside a tsetse fly. A research team from the University of Würzburg's Biocenter has presented the images.
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Image: fish oil pills; Copyright: panthermedia.net/outline2015

Understanding how omega-3 dampens inflammatory reactions

29/08/2017

Omega-3 fatty acids, which we primarily get through eating fatty fish, have long been thought to be good for our health. Many dietary studies have suggested that high intake is associated with a reduced risk of various disorders. Clinical trials have also shown beneficial anti-inflammatory effects in patients taking omega-3 supplements.
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Image: boy holding up a asthma inhaler; Copyright: panthermedia.net/wavebreakmedia

Study by Aston University and Birmingham Children's Hospital shows complex relationship between weight and asthma

28/08/2017

Researchers at Aston University and clinicians at Birmingham Children's Hospital are exploring how children living with asthma can be supported to maintain a healthy weight.
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Image: tablet with the diagnosis

Inadequate recognition and treatment of infants with bacterial meningitis could lead to tragedies, warn experts

28/08/2017

Research has shown that bacterial meningitis in infants may not be being diagnosed or acted on quickly enough by medical professionals.
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Image: many different pills lying on the table; Copyright: Swiss Institute of Bioinformatics

From cancer evolution to personalized therapies

24/08/2017

Being able to predict the resistance or sensitivity of a tumour cell to a drug is a key success-factor of cancer precision therapy. But such a prediction is made difficult by the fact that genetic alterations in tumours change dynamically over time and are often interdependent, following a pattern that is poorly understood.
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Image: a box with different pills; Copyright: panthermedia.net/duskbabe

Newly discovered pathway for pain processing could lead to new treatments

24/08/2017

The discovery of a new biological pathway involved in pain processing offers hope of using existing cancer drugs to replace the use of opioids in chronic pain treatment, according to scientists at McGill University.
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Image: illustration of co‐expression networks; Copyright: KTH Royal Institute of Technology

Study offers new targets for drugs to treat fatty liver disease and liver cancer

23/08/2017

There may be no silver bullet for treating liver cancer or fatty liver disease, but knowing the right targets will help science develop the most effective treatments. Researchers in Sweden have just identified a number of drug targets that can be used in the development of new efficient treatment strategies with minimum side effects.
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Image: model of a man holding a shield and fighting against illustrated pathogens; Copyright: panthermedia.net/Andreus

Immune system can be modulated by targeted manipulation of cell metabolism

22/08/2017

In its attempt to fight a serious bacterial infection, caused by listeria, for example, the immune system can become so over-activated that the resulting inflammatory response and its consequences can quickly lead to death.
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Image: Empa’s multicellular model, which is mimicking the placental barrier: a core of connective tissue cells, surrounded by trophoblast cells; Copyright: Empa

Medication for the unborn baby

21/08/2017

An Empa team has succeeded in developing a new three-dimensional cell model of the human placental barrier. The "model organ" can quickly and reliably deliver new information on the intake of substances, such as nano-particles, by the placental barrier and on any possible toxic effects for the unborn child.
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Image: transparent brain with a tumor, highlighted in orange; Copyright: panthermedia.net/Sebastian Kaulitzki

Researchers map brain tumour cells’ adaptation to oxygen deprivation

18/08/2017

The most aggressive variant of brain tumour – glioblastoma – has an average survival rate of 15 months. There is therefore an urgent need for new treatment strategies for this group of patients. A research team from Lund University in Sweden has now identified new factors which may affect the tumour cells’ ability to resist treatment.
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Image: chalk board with sketch of sugar molecule formula; Copyright: panthermedia.net/Boris Zerwann

Cancer detection with sugar molecules

16/08/2017

Scientists from the University of Würzburg have synthesized a complex sugar molecule which specifically binds to the tumor protein Galectin-1. This could help to recognize tumors at an early stage and to combat them in a targeted manner
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Image: hand and blood sugar measuring device; Copyright: panthermedia.net/gisne

Transforming skin cells to insulin

14/08/2017

Researchers at the University of Bergen have transformed skin puncture cells from diabetes patients into insulin producing cells, using stem cell techniques. The researchers' aim is to transplant these cells under the skin of people with diabetes.
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Image: microscopic view of salmonella; Copyright: HZI/Manfred Rohde

Researchers discover Achilles' heel of bacteria

10/08/2017

Salmonellae are particularly resistant to antibiotics since they possess not only one, but two membranes that protect them from harmful substances. This makes them members of the so-called Gram-negative bacteria. Since Salmonella infections are becoming increasingly difficult to treat with antibiotics, researchers are looking for alternative agents to control these pathogens.
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Image: x-ray of the kidneys; Copyright: panthermedia.net/Sebastian Kaulitzki

Drug therapy from lethal bacteria could reduce kidney transplant rejection

09/08/2017

An experimental treatment derived from a potentially deadly microorganism may provide lifesaving help for kidney transplant patients, according to an international study led by investigators at Cedars-Sinai.
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Image: Sample of lung fibrosis; Copyright: Helmholtz Zentrum München

Cell aging in lung epithelial cells

08/08/2017

Pulmonary fibrosis can possibly be attributed to a kind of cellular aging process, which is called senescence. This has been shown by researchers from the Helmholtz Zentrum München, partner in the German Center for Lung Research (DZL). As they report in the European Respiratory Journal, they have already successfully counteracted this mechanism in the cell culture with the help of drugs.
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Image: Girl on a laptop with Google search on screen, holding a paper in the other hand; Copyright: panthermedia.net/diego.cervo

Researchers: Too much information can be a good thing

08/08/2017

In the world of health care, the phrase "too much information" – or TMI – can be a serious problem. If you Google "How to prevent cancer," for example, you will find list after list of websites claiming to have the winning strategy, with some plans presenting 20-30 steps.
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Image: A network map of coloured dots; Copyright: Jeff Leinert, NHGRI

Social interaction affects cancer patients' response to treatment

27/07/2017

How well cancer patients fared after chemotherapy was affected by their social interaction with other patients during treatment, according to a new study by researchers at the National Human Genome Research Institute (NHGRI), part of the National Institutes of Health, and the University of Oxford in the United Kingdom.
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Image: lower part of a human skeleton, hips emphasized by bright colour; copyright: panthermedia.net/Xavier POUS

Effective protection against hip fracture during cortisone treatment

20/07/2017

There is effective protection against hip fracture for the many elderly people whose skeleton is declining in strength, as a side effect of cortisone treatment. If patients receive the osteoporosis medication alendronate, it reduces the risk of hip fracture by 65 percent, as a study published in The Journal of the American Medical Association (JAMA) reveals.
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image: blood sugar monitoring device; copyright: panthermedia.net/hdcphoto

Diabetes complications are a risk factor for repeat hospitalizations, study shows

18/07/2017

People who were previously hospitalized for severe hypoglycemia or hyperglycemia are at highest risk for recurrent dysglycemic episodes in the short term (within 30 days of the prior episode) and over the long term.
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image: human genes; copyright: panthermedia.net/krishna creations

New gene therapy treatment routes for motor neurone disease uncovered in new study

18/07/2017

Scientists investigating the genetic causes and altered functioning of nerve cells in motor neurone disease (MND) have discovered a new mechanism that could lead to fresh treatment approaches for one of the most common forms of the disease.
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image: people using laptops; copyright: panthermedia.net/danr13

Digital communication improves young patient engagement, according to new study

17/07/2017

Using texts, emails, Skype and other digital communication methods can improve the health care experience of younger patients.That is the conclusion of new research, led by the University of Warwick and King's College London, which examined case studies from 20 NHS specialist clinical teams from across England and Wales.
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Photo: Anti gravity treadmill; Copyright: Karen Hambly

Anti-gravity treadmills get patients running again after knee surgery

13/07/2017

Anti-gravity treadmills get patients running again after knee surgery. Patients recovering from knee operations are being helped back to sport and exercise through expert rehabilitation at the University of Kent.
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Image: Muscle biopsy; Copyright: Universität Basel, Biozentrum

Designed proteins to treat muscular dystrophy

12/07/2017

A new study reports widespread agreement among physicians that maintaining electronic health records (EHRs) undermines their connection with patients. The analysis found, however, that hospital-based physicians most often decried how EHRs take time away from patient contact, while office-based physicians most often lamented that EHRs detract from the quality of their patient interactions.
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Graphic: DNA; Copyright: panthermedia.net/twindesigner

Extensive funding for research on chromatin, adrenal gland, and cancer therapy

07/07/2017

At the end of May, the Joint Committee of the German Research Foundation (DFG) decided on the funding for Collaborative Research Centers (Sonderforschungsbereiche, SFBs). The Helmholtz Zentrum München is participating in three of the selected projects. A total of around 5.3 million euros will be distributed to the participating institutes over a period of four years starting on July 1.
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Graphic of how a key development regulator is regulated; Copyright: Joshua-Tor lab, CSHL

Freeze-frames of enzymes in action have implications for a new cancer treatment concept

05/07/2017

Over millions of years of evolution, cells have developed myriad ways of regulating the processes that enable them to thrive. Especially useful tools have been saved, or "conserved," over the eons, so that today we can find them in a broad spectrum of life forms, from the very primitive to the most complex. New research sheds light on how one such conserved mechanism works.
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Image: Imaging of a brain. The different regions are marked in different colors; Copyright: Andreas Horn, Charité

Correct connections are crucial

30/06/2017

Working with colleagues from Harvard Medical School and Würzburg, researchers from Charité - Universitätsmedizin Berlin have been examining the use of deep brain stimulation in the treatment of Parkison's disease in an attempt to optimize treatment effectiveness.
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