Public Health & Associations -- MEDICA Trade Fair

Image: image of how Taxanes induce tripolar instead of normal bipolar cell division; Copyright: Munich University Hospital

Cancer drug stimulates tripolar mode of mitosis


Taxanes inhibit cell division and make cancer cells sensitive to radiation therapy. A current study has investigated the underlying mechanisms of this action – and which biomarkers may be useful for predicting the success of therapy.
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"If silence is dangerous" – International Patient Safety Day 2017


In this year, the 3rd International Patient Safety Day takes place under the topic „If silence is dangerous“. On Sunday, 17th September 2017, and during the following week, all interested stakeholders in the health care system can inform themselves about the subject of patient safety and discuss it with others.
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Asthma drug from the garden center


The coralberry could offer new hope for asthmatics: researchers at the University of Bonn have extracted a new kind of active pharmaceutical ingredient from its leaves to combat this widespread respiratory disease.
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Thorough analysis reveals immune system dynamics after immunotherapy


By combining new system-biological analyses and advanced data analysis, researchers at Karolinska Institutet have been able to monitor the maturation process of the immune system of leukaemia patients who have undergone stem cell transplantation.
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New osteoporosis treatment uses traditional Chinese herb to prevent bone loss


An herb widely used in traditional Chinese medicine might hold the key to a new osteoporosis therapy that could prevent bone loss without causing side effects.
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How new blood vessels sprout


IBS biologists discovered a key regulator of normal as well as pathological formation of new blood vessels.
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Image: Diagram of the research results; Copyright: Osaka University

New drug targets for a rare kidney and liver disease


In a joint international study, researchers from Osaka University have partnered with research groups from the United States and Spain to uncover how mutations in a single gene called PKHD1 lead to symptoms associated with a rare kidney and liver disease, ARPKD (autosomal recessive polycystic kidney disease).
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Treating arthritis with algae


Researchers at ETH Zurich, Empa and the Norwegian research institute SINTEF are pursuing a new approach to treating arthritis. This is based on a polysaccharide, a long-chain sugar molecule, originating from brown algae.
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Recurrence of prostate cancer could be reduced thanks to exciting new discovery


Ground breaking research could reduce the recurrence of prostate cancer in males, a new study in the journal Nature Communications reports.
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Mayo Clinic researchers review the clinical potential of senolytic drugs on aging


Researchers are moving closer to realizing the clinical potential of drugs that have previously been shown to support healthy aging in animals.
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New insights into the world of trypanosomes


Such detailed images of the pathogen that causes sleeping sickness inside a host are unique so far: They illustrate the manifold ways in which the parasites move inside a tsetse fly. A research team from the University of Würzburg's Biocenter has presented the images.
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Understanding how omega-3 dampens inflammatory reactions


Omega-3 fatty acids, which we primarily get through eating fatty fish, have long been thought to be good for our health. Many dietary studies have suggested that high intake is associated with a reduced risk of various disorders. Clinical trials have also shown beneficial anti-inflammatory effects in patients taking omega-3 supplements.
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Study by Aston University and Birmingham Children's Hospital shows complex relationship between weight and asthma


Researchers at Aston University and clinicians at Birmingham Children's Hospital are exploring how children living with asthma can be supported to maintain a healthy weight.
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Inadequate recognition and treatment of infants with bacterial meningitis could lead to tragedies, warn experts


Research has shown that bacterial meningitis in infants may not be being diagnosed or acted on quickly enough by medical professionals.
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Image: many different pills lying on the table; Copyright: Swiss Institute of Bioinformatics

From cancer evolution to personalized therapies


Being able to predict the resistance or sensitivity of a tumour cell to a drug is a key success-factor of cancer precision therapy. But such a prediction is made difficult by the fact that genetic alterations in tumours change dynamically over time and are often interdependent, following a pattern that is poorly understood.
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Newly discovered pathway for pain processing could lead to new treatments


The discovery of a new biological pathway involved in pain processing offers hope of using existing cancer drugs to replace the use of opioids in chronic pain treatment, according to scientists at McGill University.
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Image: illustration of co‐expression networks; Copyright: KTH Royal Institute of Technology

Study offers new targets for drugs to treat fatty liver disease and liver cancer


There may be no silver bullet for treating liver cancer or fatty liver disease, but knowing the right targets will help science develop the most effective treatments. Researchers in Sweden have just identified a number of drug targets that can be used in the development of new efficient treatment strategies with minimum side effects.
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Immune system can be modulated by targeted manipulation of cell metabolism


In its attempt to fight a serious bacterial infection, caused by listeria, for example, the immune system can become so over-activated that the resulting inflammatory response and its consequences can quickly lead to death.
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Image: Empa’s multicellular model, which is mimicking the placental barrier: a core of connective tissue cells, surrounded by trophoblast cells; Copyright: Empa

Medication for the unborn baby


An Empa team has succeeded in developing a new three-dimensional cell model of the human placental barrier. The "model organ" can quickly and reliably deliver new information on the intake of substances, such as nano-particles, by the placental barrier and on any possible toxic effects for the unborn child.
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Image: transparent brain with a tumor, highlighted in orange; Copyright: Kaulitzki

Researchers map brain tumour cells’ adaptation to oxygen deprivation


The most aggressive variant of brain tumour – glioblastoma – has an average survival rate of 15 months. There is therefore an urgent need for new treatment strategies for this group of patients. A research team from Lund University in Sweden has now identified new factors which may affect the tumour cells’ ability to resist treatment.
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Image: chalk board with sketch of sugar molecule formula; Copyright: Zerwann

Cancer detection with sugar molecules


Scientists from the University of Würzburg have synthesized a complex sugar molecule which specifically binds to the tumor protein Galectin-1. This could help to recognize tumors at an early stage and to combat them in a targeted manner
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Transforming skin cells to insulin


Researchers at the University of Bergen have transformed skin puncture cells from diabetes patients into insulin producing cells, using stem cell techniques. The researchers' aim is to transplant these cells under the skin of people with diabetes.
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Image: microscopic view of salmonella; Copyright: HZI/Manfred Rohde

Researchers discover Achilles' heel of bacteria


Salmonellae are particularly resistant to antibiotics since they possess not only one, but two membranes that protect them from harmful substances. This makes them members of the so-called Gram-negative bacteria. Since Salmonella infections are becoming increasingly difficult to treat with antibiotics, researchers are looking for alternative agents to control these pathogens.
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Image: x-ray of the kidneys; Copyright: Kaulitzki

Drug therapy from lethal bacteria could reduce kidney transplant rejection


An experimental treatment derived from a potentially deadly microorganism may provide lifesaving help for kidney transplant patients, according to an international study led by investigators at Cedars-Sinai.
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Image: Sample of lung fibrosis; Copyright: Helmholtz Zentrum München

Cell aging in lung epithelial cells


Pulmonary fibrosis can possibly be attributed to a kind of cellular aging process, which is called senescence. This has been shown by researchers from the Helmholtz Zentrum München, partner in the German Center for Lung Research (DZL). As they report in the European Respiratory Journal, they have already successfully counteracted this mechanism in the cell culture with the help of drugs.
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Image: Girl on a laptop with Google search on screen, holding a paper in the other hand; Copyright:

Researchers: Too much information can be a good thing


In the world of health care, the phrase "too much information" – or TMI – can be a serious problem. If you Google "How to prevent cancer," for example, you will find list after list of websites claiming to have the winning strategy, with some plans presenting 20-30 steps.
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Image: A network map of coloured dots; Copyright: Jeff Leinert, NHGRI

Social interaction affects cancer patients' response to treatment


How well cancer patients fared after chemotherapy was affected by their social interaction with other patients during treatment, according to a new study by researchers at the National Human Genome Research Institute (NHGRI), part of the National Institutes of Health, and the University of Oxford in the United Kingdom.
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Image: lower part of a human skeleton, hips emphasized by bright colour; copyright: POUS

Effective protection against hip fracture during cortisone treatment


There is effective protection against hip fracture for the many elderly people whose skeleton is declining in strength, as a side effect of cortisone treatment. If patients receive the osteoporosis medication alendronate, it reduces the risk of hip fracture by 65 percent, as a study published in The Journal of the American Medical Association (JAMA) reveals.
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Diabetes complications are a risk factor for repeat hospitalizations, study shows


People who were previously hospitalized for severe hypoglycemia or hyperglycemia are at highest risk for recurrent dysglycemic episodes in the short term (within 30 days of the prior episode) and over the long term.
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New gene therapy treatment routes for motor neurone disease uncovered in new study


Scientists investigating the genetic causes and altered functioning of nerve cells in motor neurone disease (MND) have discovered a new mechanism that could lead to fresh treatment approaches for one of the most common forms of the disease.
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Digital communication improves young patient engagement, according to new study


Using texts, emails, Skype and other digital communication methods can improve the health care experience of younger patients.That is the conclusion of new research, led by the University of Warwick and King's College London, which examined case studies from 20 NHS specialist clinical teams from across England and Wales.
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Photo: Anti gravity treadmill; Copyright: Karen Hambly

Anti-gravity treadmills get patients running again after knee surgery


Anti-gravity treadmills get patients running again after knee surgery. Patients recovering from knee operations are being helped back to sport and exercise through expert rehabilitation at the University of Kent.
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Image: Muscle biopsy; Copyright: Universität Basel, Biozentrum

Designed proteins to treat muscular dystrophy


A new study reports widespread agreement among physicians that maintaining electronic health records (EHRs) undermines their connection with patients. The analysis found, however, that hospital-based physicians most often decried how EHRs take time away from patient contact, while office-based physicians most often lamented that EHRs detract from the quality of their patient interactions.
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Extensive funding for research on chromatin, adrenal gland, and cancer therapy


At the end of May, the Joint Committee of the German Research Foundation (DFG) decided on the funding for Collaborative Research Centers (Sonderforschungsbereiche, SFBs). The Helmholtz Zentrum München is participating in three of the selected projects. A total of around 5.3 million euros will be distributed to the participating institutes over a period of four years starting on July 1.
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Graphic of how a key development regulator is regulated; Copyright: Joshua-Tor lab, CSHL

Freeze-frames of enzymes in action have implications for a new cancer treatment concept


Over millions of years of evolution, cells have developed myriad ways of regulating the processes that enable them to thrive. Especially useful tools have been saved, or "conserved," over the eons, so that today we can find them in a broad spectrum of life forms, from the very primitive to the most complex. New research sheds light on how one such conserved mechanism works.
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Image: Imaging of a brain. The different regions are marked in different colors; Copyright: Andreas Horn, Charité

Correct connections are crucial


Working with colleagues from Harvard Medical School and Würzburg, researchers from Charité - Universitätsmedizin Berlin have been examining the use of deep brain stimulation in the treatment of Parkison's disease in an attempt to optimize treatment effectiveness.
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