20/10/2017Bacteria keep developing new resistances to antibiotics. There is a desperate need for new medications. The biggest hurdle in developing these new medications is getting them from the laboratory and into clinical trials. iCAIR will use selected lighthouse projects to establish and demonstrate its position as an expert preclinical development platform for new anti-infective drugs.
18/10/2017A new study into the genetics underlying restless legs syndrome has identified 13 previously-unknown genetic risk variants, while helping inform potential new treatment options for the condition.
17/10/2017The Hepatitis C (HCV) virus is a sly enemy to have in one’s body. Not only does it manage to make itself invisible to the immune system by breaking down communication between the immune cells, it also builds secret virus "factories" that quickly go into mass production.
16/10/2017Results from a large randomized, placebo-controlled clinical trial in Liberia show that two candidate Ebola vaccines pose no major safety concerns and can elicit immune responses by one month after initial vaccination that last for at least one year.
13/10/2017How much radiation or chemotherapy can a certain person handle? With help from blood or tissue testing, it may be possible to answer this question in advance, which in turn could improve treatment, as research at Sahlgrenska Academy shows.
13/10/2017A study has given new insights into how sleep contributes to brain plasticity – the ability for our brain to change and reorganise itself – and could pave the way for new ways to help people with learning and memory disorders.
12/10/2017Cancer researchers have long hailed p53, a tumor-suppressor protein, for its ability to keep unruly cells from forming tumors. But for such a highly studied protein, p53 has hidden its tactics well.
11/10/2017Rice, UTHealth researchers use light-sensitive molecules to track proteins critical to cell signaling.
10/10/2017Research led by Dr. Carlos Arteaga, Director of the Harold C. Simmons Comprehensive Cancer Center, has identified potential targets for treatment of triple negative breast cancer, the most aggressive form of breast cancer.
09/10/2017Premature babies that need ventilation to support their breathing often suffer from a condition known as bronchopulmonary dysplasia. Researchers at the Helmholtz Zentrum München, partner in the German Center for Lung Research (DZL), have now discovered a molecular mechanism that plays a key role in the development of the disease.
06/10/2017In a large-scale testing procedure, scientists from Cologne University Hospital have explored the effects of more than 1,500 substances on different kinds of cancer cells. The results from this study are a fundamental prerequisite for the development of new therapies for NMC, an aggressive cancer which is often lethal.
06/10/2017For some medical complaints, open-label placebos work just as well as deceptive ones. As psychologists from the University of Basel and Harvard Medical School report in the journal 'Pain', the accompanying rationale plays an important role when administering a placebo.
03/10/2017After a stroke, many people are unable to successfully perform basic hand movements in everyday life. The reason are symptoms of hemiparesis resulting from damage to the brain. These very frequently affect fine motor skills. A team from the Technical University of Munich (TUM) is now paving the way to better diagnosis and more targeted therapy.
03/10/2017The University of Twente carried out the first study worldwide that shows patients with COPD (lung disease caused by smoking) and other illnesses (heart disease, diabetes, anxiety and depression) have better outcomes if they follow a self-management programme with a customised action plan. Anke Lenferink of UT recently obtained a doctoral degree on this subject.
29/09/2017Biomaterial-mediated delivery of blood vessel growth factors could be used as a therapeutic strategy to treat peripheral vascular disease.
29/09/2017An international team of scientists led by Dr. Carlo Vittorio Cannistraci, Junior Group Leader of the Biomedical Cybernetics lab at the BIOTEChnology Center TU Dresden, has developed a powerful computational method that can exploit the principles of brain-network self-organization.
28/09/2017Different surface topographies and materials provide interesting ways to study cell behaviour and potentially provide novel solutions for treating joint defects. Tissue engineering methods that simulate native cartilage could prove useful to create cartilage implants in the laboratory, according to a doctoral dissertation from Umeå University.
28/09/2017A Norwegian study shows that the taking of diabetes medicine reduces the risk of getting Parkinson's disease.
27/09/2017Living lactic acid bacteria, probiotics, can change the intestinal flora of patients with cancer of the colon. These are the findings of a study published in the journal BMJ Open Gastroenterology.
26/09/2017Chronic throat irritation, a permanent globus sensation, a sore or dry sensation in the throat are common symptoms, which are often trivialised and wrongly attributed to gastro-oesophageal reflux disease. However, these are also the characteristic symptoms of patients suffering from displaced gastric mucosa in the oesophagus (ectopic mucosa).
25/09/2017This knowledge can provide targets in the search for novel bone-loss therapeutics to treat osteoporosis.
22/09/2017The treatment of brain diseases is on the verge of a breakthrough. Researchers from Aalborg University are developing a new method that 'smuggles' medicine past the brain's defense systems, giving hope that diseases such as Alzheimer's can one day be cured.
21/09/2017Taxanes inhibit cell division and make cancer cells sensitive to radiation therapy. A current study has investigated the underlying mechanisms of this action – and which biomarkers may be useful for predicting the success of therapy.
15/09/2017In this year, the 3rd International Patient Safety Day takes place under the topic „If silence is dangerous“. On Sunday, 17th September 2017, and during the following week, all interested stakeholders in the health care system can inform themselves about the subject of patient safety and discuss it with others.
15/09/2017The coralberry could offer new hope for asthmatics: researchers at the University of Bonn have extracted a new kind of active pharmaceutical ingredient from its leaves to combat this widespread respiratory disease.
13/09/2017By combining new system-biological analyses and advanced data analysis, researchers at Karolinska Institutet have been able to monitor the maturation process of the immune system of leukaemia patients who have undergone stem cell transplantation.
12/09/2017An herb widely used in traditional Chinese medicine might hold the key to a new osteoporosis therapy that could prevent bone loss without causing side effects.
11/09/2017IBS biologists discovered a key regulator of normal as well as pathological formation of new blood vessels.
07/09/2017In a joint international study, researchers from Osaka University have partnered with research groups from the United States and Spain to uncover how mutations in a single gene called PKHD1 lead to symptoms associated with a rare kidney and liver disease, ARPKD (autosomal recessive polycystic kidney disease).
06/09/2017Researchers at ETH Zurich, Empa and the Norwegian research institute SINTEF are pursuing a new approach to treating arthritis. This is based on a polysaccharide, a long-chain sugar molecule, originating from brown algae.
06/09/2017Ground breaking research could reduce the recurrence of prostate cancer in males, a new study in the journal Nature Communications reports.
05/09/2017Researchers are moving closer to realizing the clinical potential of drugs that have previously been shown to support healthy aging in animals.
29/08/2017Such detailed images of the pathogen that causes sleeping sickness inside a host are unique so far: They illustrate the manifold ways in which the parasites move inside a tsetse fly. A research team from the University of Würzburg's Biocenter has presented the images.
29/08/2017Omega-3 fatty acids, which we primarily get through eating fatty fish, have long been thought to be good for our health. Many dietary studies have suggested that high intake is associated with a reduced risk of various disorders. Clinical trials have also shown beneficial anti-inflammatory effects in patients taking omega-3 supplements.
28/08/2017Researchers at Aston University and clinicians at Birmingham Children's Hospital are exploring how children living with asthma can be supported to maintain a healthy weight.
28/08/2017Research has shown that bacterial meningitis in infants may not be being diagnosed or acted on quickly enough by medical professionals.
24/08/2017Being able to predict the resistance or sensitivity of a tumour cell to a drug is a key success-factor of cancer precision therapy. But such a prediction is made difficult by the fact that genetic alterations in tumours change dynamically over time and are often interdependent, following a pattern that is poorly understood.
24/08/2017The discovery of a new biological pathway involved in pain processing offers hope of using existing cancer drugs to replace the use of opioids in chronic pain treatment, according to scientists at McGill University.
23/08/2017There may be no silver bullet for treating liver cancer or fatty liver disease, but knowing the right targets will help science develop the most effective treatments. Researchers in Sweden have just identified a number of drug targets that can be used in the development of new efficient treatment strategies with minimum side effects.
22/08/2017In its attempt to fight a serious bacterial infection, caused by listeria, for example, the immune system can become so over-activated that the resulting inflammatory response and its consequences can quickly lead to death.
21/08/2017An Empa team has succeeded in developing a new three-dimensional cell model of the human placental barrier. The "model organ" can quickly and reliably deliver new information on the intake of substances, such as nano-particles, by the placental barrier and on any possible toxic effects for the unborn child.
18/08/2017The most aggressive variant of brain tumour – glioblastoma – has an average survival rate of 15 months. There is therefore an urgent need for new treatment strategies for this group of patients. A research team from Lund University in Sweden has now identified new factors which may affect the tumour cells’ ability to resist treatment.
16/08/2017Scientists from the University of Würzburg have synthesized a complex sugar molecule which specifically binds to the tumor protein Galectin-1. This could help to recognize tumors at an early stage and to combat them in a targeted manner
14/08/2017Researchers at the University of Bergen have transformed skin puncture cells from diabetes patients into insulin producing cells, using stem cell techniques. The researchers' aim is to transplant these cells under the skin of people with diabetes.
10/08/2017Salmonellae are particularly resistant to antibiotics since they possess not only one, but two membranes that protect them from harmful substances. This makes them members of the so-called Gram-negative bacteria. Since Salmonella infections are becoming increasingly difficult to treat with antibiotics, researchers are looking for alternative agents to control these pathogens.
09/08/2017An experimental treatment derived from a potentially deadly microorganism may provide lifesaving help for kidney transplant patients, according to an international study led by investigators at Cedars-Sinai.
08/08/2017Pulmonary fibrosis can possibly be attributed to a kind of cellular aging process, which is called senescence. This has been shown by researchers from the Helmholtz Zentrum München, partner in the German Center for Lung Research (DZL). As they report in the European Respiratory Journal, they have already successfully counteracted this mechanism in the cell culture with the help of drugs.
08/08/2017In the world of health care, the phrase "too much information" – or TMI – can be a serious problem. If you Google "How to prevent cancer," for example, you will find list after list of websites claiming to have the winning strategy, with some plans presenting 20-30 steps.
27/07/2017How well cancer patients fared after chemotherapy was affected by their social interaction with other patients during treatment, according to a new study by researchers at the National Human Genome Research Institute (NHGRI), part of the National Institutes of Health, and the University of Oxford in the United Kingdom.