Noninvasive Brain Tumor Treatment Is Possible -- MEDICA - World Forum for Medicine

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UA study links sleep loss with nighttime snacking

20/06/2018

The study found poor sleep quality was associated with nighttime snacking and a high likelihood of craving junk food. The study also found that junk food cravings were associated with increased risk of obesity, diabetes and other health problems.
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Why do some sleep-deprived people experience worse cognitive functioning than others?

19/06/2018

Penn study reveals that microRNAs predict differences in cognitive impairment in memory and attention after sleep deprivation.
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Image: left: mouse waiting for a reward for a short time; right: mouse waiting for a long time ; Copyright: OIST

Wait for it: Serotonin and confidence at the root of patience

18/06/2018

Serotonin keeps mice hanging on if they are sure of getting rewards, but not sure when.
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How does alcohol influence the development of Alzheimer's disease?

11/06/2018

Research from the University of Illinois at Chicago has found that some of the genes affected by alcohol and inflammation are also implicated in processes that clear amyloid beta - the protein that forms globs of plaques in the brain and which contributes to neuronal damage and the cognitive impairment associated with Alzheimer's disease.
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Space-like gravity weakens biochemical signals in muscle formation

30/05/2018

Microgravity conditions affect DNA methylation of muscle cells, slowing their differentiation.
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Subtle hearing loss while young changes brain function, study finds

29/05/2018

Early damage could open door to dementia, lead author says.
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Image: Image from a confocal microscope showing so-called pin-wheel structure of the lateral wall of the lateral ventricle; Copyright: Helmholtz Zentrum München

Everything flows: cerebrospinal fluid regulates neural stem cell division

22/05/2018

Stem cells in the brain can divide and mature into neurons participating in various brain functions, including memory. In a paper published in the journal Cell Stem Cell, scientists at Helmholtz Zentrum München and Ludwig-Maximilians-Universität München have shown how this works. They found that ion channels play a key role in mediating force signals to the neural stem cells to activate them.
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Image: PET scan showing clumping proteins in rat hearts (top). The enlarged heart (right) is one with heart failure. Other PET scans showing blood flow; Copyright: Circulation Research, May 11, 2018

Heart failure: The Alzheimer's disease of the heart?

18/05/2018

Protein clumping may contribute to heart failure development and could be used as a diagnostic tool for testing therapies or disease progression.
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Untangling brain neuron dysfunction in Parkinson's disease and dementia with Lewy bodies

17/05/2018

A neuron model of Parkinson's disease and Lewy body dementias shows defects that could suggest treatments to halt or reverse cognitive impairments before the neurons die.
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Brain cholesterol associated with increased risk of Alzheimer's disease

15/05/2018

Researchers have shown how cholesterol – a molecule normally linked with cardiovascular diseases – may also play an important role in the onset and progression of Alzheimer's disease.
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Image: binding of nNOS to the protein NOS1AP; Copyright: University of Turku

New approach for treating neuropathic pain

08/05/2018

Neuropathic pain is the chronic, pathological pain that continues even when the cause of pain is removed. Causes include damage to nerve cells and medicines used to treat cancer. A collaboration between research groups from USA and Finland has discovered a novel therapeutic that appears to interrupt the signaling cascades in the body required for multiple forms of neuropathic pain.
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Higher aerobic fitness levels are associated with better word production skills in healthy older adults

01/05/2018

Healthy older people who exercise regularly are less inclined to struggle to find words to express themselves, research led by the University of Birmingham has discovered.
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Penn Medicine-led study reveals potential for more precise diagnosis and treatment of TBI

01/05/2018

New study presented at American Academy of Neurology Annual Meeting.
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Meditation could help anxiety and cardiovascular health

27/04/2018

It sounds like a late-night commercial: In just one hour you can reduce your anxiety levels and some heart health risk factors. But a recent study with 14 participants shows preliminary data that even a single session of meditation can have cardiovascular and psychological benefits for adults with mild to moderate anxiety.
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Image: Florescent cells in the prelimbic prefrontal cortex brain regions, with inset; Copyright: Andrew Moberly, Perelman School of Medicine, University of Pennsylvania

Fight, flight, or freeze

26/04/2018

"Take a deep breath" is the mantra of every anxiety-reducing advice list ever written. And for good reason. There's increasing physiological evidence connecting breathing patterns with the brain regions that control mood and emotion.
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Eating more fish could prevent Parkinson's disease

25/04/2018

A new study from Chalmers University of Technology, Sweden, shines more light on the link between consumption of fish and better long-term neurological health. Parvalbumin, a protein found in great quantities in several different fish species, has been shown to help prevent the formation of certain protein structures closely associated with Parkinson's disease.
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Image: Abnormally activated astrocytes were accumulated in the lesion of ALS mouse without TRIF signaling; Copyright: Koji Yamanaka

Innate immune adaptor TRIF confers neuroprotection in ALS mice by eliminating abnormal glial cells

20/04/2018

Researchers led by Nagoya University revealed that deficiency of the innate immune adaptor TRIF significantly shortened survival time of ALS mice.
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Image: two scientists in the laboratory - Drs. Kumar Vaibhav Krishnan Dhandapani; Copyright: Phil Jones, Senior Photographer, Augusta University

Receptor that feels the heat of a red chili pepper may be target for TBI recovery

16/04/2018

A receptor on our immune cells that can detect both the heat of a red chili pepper and the extreme physical heat of a pizza oven may help protect the brain following a traumatic brain injury, scientists say.
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The brain combats dementia by shifting resources

13/04/2018

The brain continues to put up a fight even as neurodegenerative diseases like dementia damage certain areas and functions. In fact, recent findings in a Baycrest-University of Arizona study suggest that one method the brain uses to counter these diseases is the reassigning of tasks to different regions.
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How to reprogram memory cells in the brain

12/04/2018

Long-term memory of specific places is stored in the brain in so-called place cells. A team of neuroscientists headed by Dr Andrea Burgalossi of the University of Tübingen's Werner Reichardt Centre for Integrative Neuroscience (CIN) have now 'reprogrammed' such place cells in free-roaming mice, by sending electrical impulses directly to individual neurons.
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Stressing out about granule proteins

09/04/2018

MPI-P group leader Sapun Parekh and Brown University Professor Nick Fawzi have received $750,000 from the Human Frontier in Science Program (HFSP) over the next 3 years to study the "Structure and biophysics of disordered domains mediating RNP granules: from atoms to cells".
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Image: Professor Sharma wearing a lower-limb exoskeleton in his neuromuscular control and robotics laboratory; Copyright: Sharma Lab/University of Pittsburgh

Using ultrasound to help people walk again

06/04/2018

Pitt engineer wins NSF CAREER award to develop ultrasound technology that measures muscle movement in incomplete spinal cord injuries.
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Long-term caffeine worsens anxiety symptoms and fear of the new associated with Alzheimer's disease

06/04/2018

A study coordinated by the Institute of Neuroscience of the Universitat Autònoma de Barcelona (Inc-UAB) and in collaboration with the Karolinska Institutet (KI) in Sweden provides evidence that a long-term consumption of caffeine has negative effects for Alzheimer's disease.
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Alzheimer's disease: patients exhibit changes in certain blood lipids that are typical of premature ageing

28/03/2018

The neurodegenerative condition known as Alzheimer's disease is the commonest cause of dementia. A research group led by molecular biologists Fabian Dorninger and Johannes Berger at MedUni Vienna's Centre for Brain Research investigated changes in certain lipids (choline phospholipids) in the plasma of elderly people who were healthy and those suffering from Alzheimer's disease.
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Image: Tau proteins accumulated in the brain of a patient with PSP-like symptoms; Copyright: Yabe I. et al., Scientific Reports

The bassoon causing new brain disorder

26/03/2018

Mutations have been found in the bassoon (BSN) gene, which is involved with the central nervous system, in patients with symptoms similar to, but different from, a rare brain disorder called progressive supranuclear palsy (PSP).
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Radiology: machine learning to support medical diagnostics

08/03/2018

Automation makes work life easier in many ways but is it also a solution for analyzing medical images? Is a computer actually reliable enough to assist in the medical decision making process? Researchers in Landshut examine how machine learning algorithms can work more reliably and support radiologists.
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Image: Zebrafish brain, fluorescence image (left) and 3D image (right); Copyright: private

"A 3D movie of the brain in action"

08/12/2016

Watching millions of neurons in the brain interacting with each other – for a long time this was possible only to a limited extent. The current techniques can visualize only superficial layers or the imaging they use is too slow. But now, Prof Daniel Razansky and his team have found a new method to visualize the brain activity – by using optoacoustics.
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Image: Eileen Stark prepares Dominik Wetzel for a measurement; Copyright: WHZ/Helge Gerischer

Paraplegia: moving muscles using electrical impulses

22/11/2016

It happens about 1,800 times per year: after a sporting or traffic-related accident, a person’s spinal cord is injured to where nerve tracts are severed and he/she becomes paralyzed. Researchers now want to develop software that measures the brain signals of paralyzed patients and sends out electrical impulses via a system to stimulate muscles, causing them to move again.
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Image: Closed eyes of a patient. Electrodes are attached above the eyebrows; Copyright: savir-center.com

Electrical Stimulation: Using Electrical Pulses to Combat Blindness

22/07/2016

Millions of people all over the world suffer from partial blindness – caused by glaucoma, a stroke or traumatic brain injury. For years, the loss of vision was deemed irreversible. But now a new treatment makes it possible to improve eyesight and vision.
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Multiple Sclerosis: does the colon affect the immune system?

01/12/2015

Multiple sclerosis apparently can strike anyone - regardless of age, family history, lifestyle or gender. Yet why then does it not strike everyone? Genetic and environmental factors appear not to be the only reason whether it develops or not. The countless microorganisms that colonize our intestinal tract could also be involved in this.
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ECG measurements: "Our chest strap moistens itself"

01/07/2015

When measuring myocardial activity, it is important for the skin to always stay moist under the electrodes of the ECG. Only then can data be consistently transferred. Athletes have an easier time with this: they are used to sweating. This is a lot harder for older patients.
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Making Your Own End-of-Life Decisions: “All options of palliative care, pain management and continued life need to have been explained to the patient“

01/12/2014

How does a physician handle a patient, who wants to die and what rights do I actually have as a patient? Legal practitioners do not automatically answer these and other questions. We talked about this subject with MD-PhD Ralf Jox from the Institute of Ethics, History and Theory of Medicine at the Ludwig Maximilians University of Munich, Germany.
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Persistent vegetative state: brain stimulation with laser beams

01/09/2014

The public only notices diseases when celebrities become patients: in the spring of 2014, Formula One driver Michael Schumacher fell into a coma for several months as the result of a head injury caused by a skiing accident. These types of accidents show how delicate the brain responds to injuries. Brain stimulation could possibly support the rehabilitation of vegetative patients.
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Diagnosing Parkinson's: the skin is revealing

01/07/2014

In patients with Parkinson's, neural cells in the brain die off that produce the neurotransmitter dopamine. Certain physical symptoms that can indicate the disease follow years later. But a reliable diagnosis can only be made through examination of the brain after the patient's death, and not during his lifetime.
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