20/10/2017Bacteria keep developing new resistances to antibiotics. There is a desperate need for new medications. The biggest hurdle in developing these new medications is getting them from the laboratory and into clinical trials. iCAIR will use selected lighthouse projects to establish and demonstrate its position as an expert preclinical development platform for new anti-infective drugs.
17/10/2017The Hepatitis C (HCV) virus is a sly enemy to have in one’s body. Not only does it manage to make itself invisible to the immune system by breaking down communication between the immune cells, it also builds secret virus "factories" that quickly go into mass production.
16/10/2017Results from a large randomized, placebo-controlled clinical trial in Liberia show that two candidate Ebola vaccines pose no major safety concerns and can elicit immune responses by one month after initial vaccination that last for at least one year.
02/10/2017mHealth has been slated to revolutionize the healthcare market for the past few years. Yet things are not quite as easy for apps and wearables as it may seem. A recently conducted study reveals that there are still many obstacles to overcome before manufacturers and health professionals can connect with patients and their mobile devices.
22/09/2017Respiratory diseases are major causes of disease burden and mortality. They are also the focus of the latest issue of the Journal of Health Monitoring, which features a Focus article that considers acute respiratory diseases such as influenza as well as chronic lung diseases including lung cancer, chronic obstructive pulmonary disease (COPD) and asthma.
20/09/2017The low uptake of flu vaccination among medical students and doctors is influenced by social attitudes say researchers. Despite a recommendation from the Chief Medical Officer for England that all healthcare workers are vaccinated annually, only 55 percent are protected against the spread of influenza, this could contribute to staff sickness and mortality among elderly patients.
08/09/2017Adenoviral infections have a mild disease progression in healthy people, but it can be dangerous for immunocompromised people. If a patient is infected with the virus and gets a bacterial infection on top of it, it can lead to an excessive inflammatory response known as a cytokine storm, an overreaction by the immune system leading to high concentrations of proteins that promote inflammation.
01/09/2017Scientists at IRB Barcelona identify a key component of the machinery that allows Staphylococcus aureus to transfer genes that confer antibiotic resistance.
01/09/2017There are many causes of myocarditis or inflammation of the heart muscle. Oftentimes, the culprits are viruses or bacteria and sometimes even an acute heart attack. Regardless of the cause, it creates a challenge for cardiologists: a diagnosis tends to be only nonspecific without a biopsy. A cardiac MRI and molecular imaging promise to provide assistance.
22/08/2017In its attempt to fight a serious bacterial infection, caused by listeria, for example, the immune system can become so over-activated that the resulting inflammatory response and its consequences can quickly lead to death.
17/08/2017Genetic differences in immune response demonstrate interaction of genetics and environment linked to disease risk.
17/08/2017For most of us, the flu is just the flu. We suffer through it for several days, and eventually bounce back. But for patients with multiple sclerosis (MS) and other neurological diseases, the flu can trigger a cascade of immune responses that result in a full-blown relapse of the disease.
11/08/2017The impact of climate change on the emergence and spread of infectious diseases could be greater than previously thought, according to new research by the University of Liverpool.
10/08/2017Salmonellae are particularly resistant to antibiotics since they possess not only one, but two membranes that protect them from harmful substances. This makes them members of the so-called Gram-negative bacteria. Since Salmonella infections are becoming increasingly difficult to treat with antibiotics, researchers are looking for alternative agents to control these pathogens.
03/08/2017Malaria was already widespread on Sardinia by the Roman period, long before the Middle Ages, as indicated by research at the Institute of Evolutionary Medicine of the University of Zurich with the help of a Roman who died 2,000 years ago.
01/08/2017An increasing percentage of the world population suffers from chronic inflammatory disorders of the respiratory system. Acute attacks often lead to a worsening of the disease and considerably reduce the patient’s lung volume. Nine institutes of a research alliance under the Leibniz Institute umbrella are working on technologies designed to predict and thus prevent exacerbations.
28/07/2017Vaccinations or at least an early diagnosis are vital to effectively eliminate viral hepatitis – the disease is still a global public health threat. The annual World Hepatitis Day aims to raise awareness for the disease and its prevention.
03/04/2017The laboratory is one of the most important and pivotal bastions in patient care. In the laboratory, acute, chronic and genetic diseases are diagnosed, the progression of diseases such as diabetes is regularly checked or specialists look for biomarkers to adapt cancer therapies.
03/04/2017Instant treatment is absolute vital for patients developing sepsis. Providing a specific therapy early on is key. To manage this the pathogenic organisms need to be identified accurately. But a fungal sepsis can still be a hard nut to crack.
03/04/2017Many aspects are uniformly regulated in Europe, however, hospital hygiene and MRSA prevention, for example, are not. The Netherlands plays a pioneering role in the fight against hospital-acquired infections. The country is an often-cited role model. But can other countries simply adopt the same system? And what makes it so different? MEDICA asked expert Prof. Alexander W. Friedrich.
09/01/2017Hospitals apply many infection prevention and control measures. They all have one thing in common: they are individual parts of an overall concept that is aimed at preventing the spread of highly infectious and resistant pathogens in hospitals. Nevertheless, previous hygiene concepts ignore one aspect of hospitals: the architecture of the actual hospital facility itself.
21/12/2016Within the scope of the VIRUSCAN project that is funded by the Horizon 2020 Research and Innovation Program of the European Union, Dr. Charlotte Uetrecht from Hamburg/Germany investigates individual viruses to be able to later identify them on a nanospring structure. MEDICA.de wanted to know: how does this work?
01/06/2016Some hospitals have long banned the status symbol of physicians – the white coat. Research has shown that especially the sleeves were contaminated with various types of bacteria. But it’s not just lab coats that can spread germs in healthcare settings. This field uses a variety of different textiles. Wouldn’t it, therefore, make sense to apply antimicrobial finishes?
01/06/2016Every day, people are admitted to the hospital, discharged or they visit patients. This large number of people increases the risk of bacteria transmission. Preventative measures such as short-sleeved uniforms and copper surfaces can help by improving hospital hygiene but they cannot replace the legal requirements for hygiene measures.
22/02/2016Easy solutions that deliver results quickly are a great asset in medicine: patients receive their diagnosis faster and physicians have more time to treat them. Such tools also work without sophisticated resources and trained personal. A device currently developed in a project funded by the European Commission could bring all of this to point-of-care-testing for infectious diseases.
01/02/2016First grow tissue in the lab, then insert it into patients when they need it and you’re done! Unfortunately, things are not as easy as people hoped at the onset of “tissue engineering”. Although robust tissues for bone defects can be grown in a petri dish, for example, they unfortunately quickly die off again inside the body if there is no corresponding nutrient supply.
04/01/2016Infectious diseases are widespread in conflict areas. When basic medical care is lacking on location, people cannot be appropriately treated. Laboratory tests are limited in the field. Rapid diagnostic tests make it possible for medical personnel to quickly and accurately test patients for several infectious diseases, for instance for the presence of malaria or HIV infection.
04/01/2016Most Europeans think it was a long time ago, but the residents of West Africa clearly feel the consequences of the Ebola epidemic that broke out in December 2013 and still continues today. So far, approximately 11,300 people have died as a result of the outbreak; more than 28,000 contracted the disease.
04/01/2016When infectious diseases such as Ebola break out, a rapid diagnosis is important because the early detection of a virus along with the right hygiene measures can prevent its continued spread. However, laboratories and skilled personnel are not available everywhere. Low-cost and portable detection strips can bring relief.
01/08/2014If neither the immune system nor antibiotics are able to control an infection, a sepsis can arise out of it - an infection that attacks several organs at the same time and causes the immune system to overreact. This is a life-threatening condition.
01/08/2014Detecting infections quickly and reliably with the naked eye: This is what many doctors in hospitals and in the doctor's surgeries wish for. To make this dream come true, Prof. Holger Schönherr, a scientist from Siegen, is researching a sensor that should show an infection by a color change.
01/08/2014Bacteria lurk everywhere: on the skin, in the intestines and in every puddle. Most of them that are hanging out in the human body are good bacteria. But not all of them. Those pathogens that exhibit resistance and are thus very hard to combat are the most dangerous kind. Their spread threatens people all over the world.
22/01/2014It guards the body but can become its enemy: the immune system defends us from intruding pathogens; it is also able to cause severe diseases if it falsely recognizes the body itself as a threat. Molecular receptors in the whole body enable the immune system to “sense” what happens within.
08/01/2014Heart diseases can be triggered by special viruses that affect the cardiac muscle. Preventive drugs could definitely be developed – if the virus does not mutate.