21/06/2018Researchers have developed an artificial tissue in which human blood stem cells remain functional for a prolonged period of time. Scientists from the University of Basel, University Hospital Basel, and ETH Zurich have reported their findings in the scientific journal PNAS.
21/06/2018New study from University Hospitals Connor Integrative Health Network published in the Journal of Music Therapy.
19/06/2018If immunoglobulin E (IgE) antibodies are directed against harmless antigens such as pollen, the result can be an allergic reaction. However the original purpose of these IgE antibodies is to repel harmful exogenous substances rather than to trigger allergies.
18/06/2018Serotonin keeps mice hanging on if they are sure of getting rewards, but not sure when.
18/06/2018Researchers at the Cells-in-Motion Cluster of Excellence have decoded a mechanism found at the beginning of almost every inflammatory response. Their study provides a new approach to develop novel treatment options for many inflammatory disorders with many fewer side effects compared to current drugs.
15/06/2018The so called "diabetic retinopathy" and the "diabetic macular edema" are two of the most frequent ocular diseases in patients with diabetes, and both feature pathologic changes of blood vessel functions in the retina. Experimental data and measurements in patients suggest that these changes in blood vessel functions may originate from a lack of vasoinhibin hormones in the retina.
15/06/2018The first antibiotic against tuberculosis that has been developed in Germany is now ready for clinical testing. BTZ043, as the newly developed drug substance is called, is also effective against multidrug-resistant pathogens which are increasingly challenging successful treatment worldwide.
14/06/2018An unexpectedtwo-step mechanism occurs when cells copy DNA.
13/06/2018A new Collaborative Research Center will start in July with a total funding of nearly 14 million euros, headed by the German Institute for Experimental Biomedicine in Würzburg. The aim is to decode the complex and insufficiently understood functions of platelets, the so-called thrombocytes.
13/06/2018The heart of a neonatal mouse is capable of self-repair after tissue damage. However, this ability disappears during the first week of life. Researchers at the University of Helsinki investigate the molecular mechanisms underlying myocardial regenerative ability.
12/06/2018Researchers at the Paul-Ehrlich-Institut have reproduced measles virus transmission in an animal model. They were able to show that an efficient interaction with two cellular receptors plays a decisive role in the efficient transmission of the virus.
12/06/2018For over a century, we have known that high altitude reduces the amount of blood the heart pumps around the body with each beat. New research published in The Journal of Physiology has unearthed why this is the case and the findings will be important for people who live, travel and exercise at high altitudes.
11/06/2018Research from the University of Illinois at Chicago has found that some of the genes affected by alcohol and inflammation are also implicated in processes that clear amyloid beta - the protein that forms globs of plaques in the brain and which contributes to neuronal damage and the cognitive impairment associated with Alzheimer's disease.
11/06/2018Women are more prone to the development of autoimmune diseases. The female hormone estrogen is likely to affect the immune system. A team of scientists from Turku Center for Biotechnology and University of Georgia reported new findings related to the involvement of estrogen hormone receptor in autoimmune diseases.
05/06/2018When cells become stressed, they activate specific response patterns. Würzburg researchers have identified new details of these responses, which can help to get a better understanding of neurodegenerative diseases.
05/06/2018Antimicrobial resistance is a major medical problem worldwide, impacting both human health and economic well-being. A new strategy for fighting bacteria has now been reported in the latest online issue of Nature by a research group headed by Prof. Dikic at the Goethe University Frankfurt. The scientists revealed the molecular action mechanism of a Legionella toxin and developed a first inhibitor.
01/06/2018A study of more than 7,000 low-income, urban mothers enrolled in the Boston Birth Cohort found that fewer than 5 percent of them started folic acid supplementation and used it almost daily before pregnancy, a widely recommended public health measure designed to prevent potentially crippling birth defects.
01/06/2018Research by physician-scientists at the University of Colorado Anschutz Medical Campus offers hope for improved quality of life for people who rely on intravenous nutrition due to intestinal damage.
31/05/2018Considering the size of red blood cells, a new model for blood flow sheds light on why blood sometimes prefers some vessels over others.
29/05/2018The more often a hospital can check its newborns for deadly MRSA germs, the more likely it will be that they are contained, according to a new study.
28/05/2018Proteins involved in metabolism, immunity disrupted after just one simulated night shift.
25/05/2018Macrophages are white blood cells involved in a variety of biological functions, from destroying infectious pathogens to repairing damaged tissue. To carry out their different roles, macrophages must first be activated and transformed into different subtypes. However, the mechanisms that lead to macrophage activation are not fully understood.
24/05/2018Fibrils of the protein alpha-synuclein, that plays a role in Parkinson's disease, form a stiffer and stronger network in water, when temperature is increased. Researchers of the University of Twente show that this has to do with the water-repellent part of the fibres coming to the surface and interacting.
18/05/2018A little-explored group of immune cells plays an important role in the regulation of intestinal bacteria. Changing metabolic states of the microbes have an effect on defense cells at different stages of alert or rest, as researchers from the Department of Biomedicine at the University and University Hospital of Basel report in the journal Mucosal Immunology.
17/05/2018One gram of fish oil a day could help reduce the pain of patients with osteoarthritis, a new study in Rheumatology reports.
17/05/2018A neuron model of Parkinson's disease and Lewy body dementias shows defects that could suggest treatments to halt or reverse cognitive impairments before the neurons die.
16/05/2018Scientists at the Goethe University have discovered that single cells in the innermost layer of blood vessels proliferate after injury and in so doing make a significant contribution to the formation of new vessels.
15/05/2018Patients with low platelet count and high homocysteine levels reduced first stroke risk by 73 percent with the B vitamin.
14/05/2018Megha Padi, Ph.D., of the UA Cancer Center has developed a method for probing the genetic underpinnings of cancer and other diseases, which could lead to better treatments.
14/05/2018Researchers from the Institute for Hygiene and Applied Immunology of the Center for Pathophysiology, Infectology and Immunology at MedUni Vienna, led by Hannes Stockinger, have discovered a hitherto unknown function of the protein lactoferrin, which is primarily found in breast milk.
10/05/2018Cancer drops sparse chemical hints of its presence early on, but unfortunately, many of them are in a class of biochemicals that could not be detected thoroughly, until now. Researchers at the Georgia Institute of Technology have engineered a chemical trap that exhaustively catches what are called glycoproteins, including minuscule traces that have previously escaped detection.
08/05/2018Immune cells that are ready to take action against invaders like bacteria have been found in women's breast milk, researchers say. They say the presence of this SWAT team of immune cells called innate lymphoid cells, or ILCs, in human breast milk is more evidence of the benefits of breastfeeding.
03/05/2018New algorithm could help overcome shortage of physicians trained in disease diagnosis.
03/05/2018UT Southwestern researchers today published in Nature atomic-scale blueprints of the most abundant class of brain nicotinic acetylcholine receptors. A structural understanding of the protein, found in neurons, could lead to new ways to treat nicotine addiction from smoking and vaping.
02/05/2018For most people with hemophilia B, whose bodies can't properly form blood clots, constant injections to replenish their clotting factors are a way of life.
01/05/2018New study presented at American Academy of Neurology Annual Meeting.
01/05/2018Healthy older people who exercise regularly are less inclined to struggle to find words to express themselves, research led by the University of Birmingham has discovered.
26/04/2018International research consortium led by researchers from the University of Helsinki, Finland, discovered new information related to a rare form of leukemia called aggressive NK-cell leukemia. Potential new treatment options were found which are highly warranted as currently this disease usually leads to rapid death of patients. The study was published in Nature Communications.
26/04/2018"Take a deep breath" is the mantra of every anxiety-reducing advice list ever written. And for good reason. There's increasing physiological evidence connecting breathing patterns with the brain regions that control mood and emotion.
25/04/2018A new study from Chalmers University of Technology, Sweden, shines more light on the link between consumption of fish and better long-term neurological health. Parvalbumin, a protein found in great quantities in several different fish species, has been shown to help prevent the formation of certain protein structures closely associated with Parkinson's disease.
24/04/2018Whether or not you develop an allergy is largely dependent upon genetic factors. This is the main finding of a study recently published in EBioMedicine, just in time for World Allergy Week (22-28. April 2018). The study was supervision of Winfried F. Pickl from MedUni Vienna's Institute of Immunology.
24/04/2018Tumor heterogeneity describes the differences between different cells within a given tumor. These differences have major implications for the diagnosis, prognosis, and therapy of cancer patients. Different mechanisms have been proposed to account for tumor heterogeneity such as epithelial to mesenchymal transition (EMT).
23/04/2018Using a Raman microscope, researchers at Ruhr-Universität Bochum have studied at which targets the cancer drug Neratinib binds in cells and how its chemical structure changes. Compared with other techniques, this method offers a considerable advantage, as it is not necessary to apply a label to the drug that would indicate its distribution indirectly; rather, the drug itself can be monitored.
23/04/2018A bypass is a complicated structure. It is either made of synthetic materials that can cause blood clots and infections or created by using the patient’s veins. However, the latter often does not yield adequate material. A newly developed bioreactor could solve this problem in the future. It is designed to tissue engineer vascular grafts by using the body’s own material.
23/04/2018Obesity is a world health problem since excessive accumulation of fat tissue (or adipose tissue) increases the risk of cardiovascular disease, hypertension, diabetes and some types of cancer. However, some obese individuals are less susceptible to these conditions.
23/04/2018The European Immunization Week's general slogan "Prevent. Protect. Immunize" is more relevant than ever in times of globalization and migration. It is a political and structural challenge to give as many people as possible access to vaccination. But even the best care is of no use if the individual does not recognize his or her duty to society.
20/04/2018Researchers led by Nagoya University revealed that deficiency of the innate immune adaptor TRIF significantly shortened survival time of ALS mice.
19/04/2018The high estrogen levels that typically afford younger women protection from cardiovascular disease appear to instead multiply their risk if they have type 1 diabetes, researchers say.
19/04/2018Research sheds light on initial phase of infectious disease and potential for prevention of pneumococcal septicaemia.
16/04/2018A receptor on our immune cells that can detect both the heat of a red chili pepper and the extreme physical heat of a pizza oven may help protect the brain following a traumatic brain injury, scientists say.
12/04/2018Long-term memory of specific places is stored in the brain in so-called place cells. A team of neuroscientists headed by Dr Andrea Burgalossi of the University of Tübingen's Werner Reichardt Centre for Integrative Neuroscience (CIN) have now 'reprogrammed' such place cells in free-roaming mice, by sending electrical impulses directly to individual neurons.
11/04/2018A new method enables genes in living T-cells in mice to be modified quickly and efficiently. It makes use of plasmids, a tried-and-tested method of genetic engineering. Researchers from the Department of Biomedicine at the University of Basel and University Hospital Basel reported these findings in the Journal of Immunology.
09/04/2018MPI-P group leader Sapun Parekh and Brown University Professor Nick Fawzi have received $750,000 from the Human Frontier in Science Program (HFSP) over the next 3 years to study the "Structure and biophysics of disordered domains mediating RNP granules: from atoms to cells".
06/04/2018A study coordinated by the Institute of Neuroscience of the Universitat Autònoma de Barcelona (Inc-UAB) and in collaboration with the Karolinska Institutet (KI) in Sweden provides evidence that a long-term consumption of caffeine has negative effects for Alzheimer's disease.
04/04/2018By modifying a muscle transplant operation, Johns Hopkins surgeons report they are able to restore authentic facial expressions of joy -- wide and even smiles - to selected patients with one-sided facial muscle paralysis due to birth defects, stroke, tumors or Bell's palsy.
03/04/2018Findings have major implications for tick-borne diseases like Lyme disease.
03/04/2018In patients with haemophilia A, the missing blood coagulation factor VIII is administered, and thus replaced, intravenously. A part of the patients, however, develops antibodies (inhibitors) against factor VIII, which, in the worst case scenario, can cause uncontrolled bleeding.
01/03/2018Everyone is different. This statement also applies to our health. Cancer, in particular, can look and progress differently depending on the individual person. That’s why every patient ideally also needs a customized treatment that is tailored to their individual needs. But how feasible is this idea?
22/02/2018Here on Earth, all experiments are bound by gravitation. Yet, freed from gravity's grip, tumor cells, for example, behave in an entirely different way. As part of the "Thyroid Cancer Cells in Space" project by the University of Magdeburg, smartphone-sized containers carrying poorly differentiated thyroid cancer cells are sent into space.
08/01/2018Few patients with heart failure are fortunate enough to receive a donor's heart. Ventricular assist devices (or heart pumps) have been around for several years and are designed to buy time as patients wait for a transplant. Unfortunately, the body doesn't always tolerate these devices.
22/08/2017Physics has always supported medical science, especially when it comes to practical implementation. Now physicists and health professionals join in collaborative research at an interdisciplinary Center in Erlangen and incorporate fundamental principles of theoretical physics in their studies of diseases.
01/08/2017Many therapeutic drugs are very powerful, but they are also very toxic at the same time. Thus, they have to be measured regularly, again and again, so that an adjustment of the individual drug dosage can be made. Until now, the "normal" way was to take the blood sample, send it to a central laboratory and get the results after some days. A new point-of-care test can measure it in 15 minutes.
03/07/2017Precision work is absolutely essential in eye surgery since the surgical site is very minute and sensitive. This is why eye surgeons have been using lasers for years. Femtosecond lasers are especially well suited to serve this purpose because they are able to cut tissue with great precision and little energy, which prevents unwanted side effects of surgery.
08/12/2016Watching millions of neurons in the brain interacting with each other – for a long time this was possible only to a limited extent. The current techniques can visualize only superficial layers or the imaging they use is too slow. But now, Prof Daniel Razansky and his team have found a new method to visualize the brain activity – by using optoacoustics.
08/08/2016What happens when stem cells differentiate? What molecular characteristics do they have? Questions that can now be easier answered with the help of a new open-source software. We spoke with Prof. Fabian Theis at the Helmholtz Center Munich, who participated in the software development.
22/07/2016Millions of people all over the world suffer from partial blindness – caused by glaucoma, a stroke or traumatic brain injury. For years, the loss of vision was deemed irreversible. But now a new treatment makes it possible to improve eyesight and vision.
09/02/2016Many people suffer from atherosclerosis, especially in developed countries. The buildup of fatty deposits inside the arterial blood vessels leads to strokes and heart attacks. Now, a new method is designed to get to the root of the problem, and with the help of nanoparticles inject new turbo replacement cells into the blood vessels which are intended to exert their curative effect.
01/02/2016Self-healing powers like a superhero on the big screen? That’s the aim of regenerative medicine; at least in a very broad sense. This promising field of biomedicine is currently highly dynamic with innovative technologies and development. New methods are designed to help propel medicine into a whole new sphere.
01/02/2016Children, especially newborns, are generally no longer simply considered to be small adults whose treatment just needs to be "reduced". This is why a pediatrician’s education includes several specialties because ultimately everything in terms of care comes together here.
01/10/2015Semiconductor nanoparticles for biomedical applications have been researched for some time now. Not only are they millionths of a millimeter in size, they also offer great potential for cancer diagnostics and therapy, so-called theranostics. They enter cells, are activated by ultrasonic radiation and destroy the cells using the generated vibration.
02/03/2015Crises come in many shapes and sizes. Whether it’s poor hygiene, thefts or treatment errors – once the crisis has arrived, things need to move quickly. For hospitals in particular, the right crisis communication is key. Yet many medical facilities still neglect the fact that crisis communication starts before the actual crisis takes place.
02/02/2015The digitization of medicine moves on. Researchers, physicians and patients equally benefit from this development – thanks to improved diagnostics with highly sensitive devices, today findings can be comprehensively analyzed and treatment decisions made on a broadened basis. Digitization also offers the area of pathology interesting fields of application.
05/01/2015T-cells are the guardians of our immune system. When they show changes, it can lead to severe inflammatory responses in the body. It is believed that the T-cells in persons who are affected by inflammatory bowel disease don’t work properly. Two proteins that can be found on activated T-cells and that interact with each other are now being analyzed.
03/11/2014The treatment of chronic wounds is extremely problematic. Chronic wounds can take months or years to heal and some even never heal resulting in over 100.000 amputations taking place annually in the US alone. A new technology from Iceland, that is based on fish skin and is already used clinically, allows for improved healing of chronic and burn wounds.
03/11/2014As an imaging procedure, magnetic resonance tomography has become essential in clinical practice, since it can easily make organs and tissue visible. However, until now abnormal cancer cells or small centers of inflammation remained almost invisible. Now cell biologists from Berlin, Germany, have succeeded in fixing this problem with xenon magnetic resonance imaging.
01/10/2014On November 10, 2014, astronaut Alexander Gerst will return to Earth from the International Space Station (ISS). He is not just anxiously expected by his family, but also by Dr. Anna-Maria Liphardt from the Institute of Biomechanics and Orthopedics at the German Sport University Cologne
01/07/2014Large burns require skin grafting. Surgeons remove split-thickness skin grafts and apply them to the injured areas. Now skin that has been made in a laboratory is meant to help in covering burns as well as chronic wounds and thus promote the healing process. Researchers in Zurich have been working on this for more than 13 years.
01/07/2014In patients with Parkinson's, neural cells in the brain die off that produce the neurotransmitter dopamine. Certain physical symptoms that can indicate the disease follow years later. But a reliable diagnosis can only be made through examination of the brain after the patient's death, and not during his lifetime.
01/07/2014The not so popular “love handles“ could revolutionize medicine in the near future. In cooperation with the University of Rostock (Professor Hermann Seitz), the human med AG Company currently seeks to develop a device that is able to gently remove adipose tissue during surgery and subsequently isolate stem cells.
03/02/2014Differentiating tumor tissue from healthy tissue isn’t always easy for surgeons. Scattered cancer cells and early cancer are often hard to detect with the naked eye. A special camera now makes even the tiniest remainder of a tumor visible during surgery.