Atherosclerosis: Getting to the root of the problem with a turbo gene -- MEDICA - World Forum for Medicine

Atherosclerosis: Getting to the root of the problem with a turbo gene

Interview with Prof Daniela Wenzel, Institute for Physiology at the University of Bonn

Many people suffer from atherosclerosis, especially in developed countries – and sometimes with deadly consequences. The buildup of fatty deposits inside the arterial blood vessels leads to strokes and heart attacks. Now, a new method is designed to get to the root of the problem, and with the help of nanoparticles inject new turbo replacement cells into the blood vessels which are intended to exert their curative effect and control blood pressure once they are at their target destination.


Photo: Daniela Wenzel

JProf. Daniela Wenzel; © Rolf Müller/Uni Bonn

Photo: Prof. Wenzel (left) and Dr. Sarah Rieck (right)

Wenzel (left) and Dr. Sarah Rieck examine how pathologically altered blood vessels regenerate by replacement cells. The picture shows a perfusion model, with which the researchers have repopulated the blood vessels of mice with endothelial cells; © Katharina Wislsperger/Ukom UKB

Photo: green fluorescent endothelial cells

The left image shows a blood vessel that has been repopulated with fluorescent cells (green). On the right a detail of a vascular wall marking eNOS protein in red; © Rieck/Vosen/Uni Bonn

Photo: Melanie Günther; Copyright: B. Frommann

© B. Frommann