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Image: group of elderly persons doing exercises; Copyright: Alonso Nichols/Tufts University

From the lab to the real world: Program for elderly mobility

18/07/2018

Immobility in old age can lead to lower independence and quality of life and increased risk for falls and chronic disease. In the Lifestyle Interventions and Independence for Elders (LIFE) study, a large multicenter clinical trial, researchers found that a regular program of structured physical activity performed in the clinical setting could reduce mobility loss in older adults.
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Image: abstract computer simulation of the signalling pathways of a human brain; Copyright: panthermedia.net/Andrew Ostrovsky

Launch of the neuroinformatics platform The Virtual Brain

16/07/2018

Charité - Universitätsmedizin Berlin and the Berlin Institute of Health (BIH) are pleased to announce that 'The Virtual Brain' neuroinformatics platform has joined the EU's Flagship 'Human Brain Project'. With financial support from the EU's Horizon 2020 research and innovation program, Charité's researchers are now integrating their open-source platform into the 'Human Brain Project'.
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Image: smiling man in a suit; Copyright: L. Brian Stauffer

New informatics tool makes the most of genomic data

16/07/2018

The rise of genomics, the shift from considering genes singly to collectively, is adding a new dimension to medical care; biomedical researchers hope to use the information contained in human genomes to make better predictions about individual health, including responses to therapeutic drugs.
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Image: three images of a brain; Copyright: Yasser Iturria Medina

Unique brain 'fingerprint' can predict drug effectiveness

13/07/2018

Personalized medicine - delivering therapies specially tailored to a patient's unique physiology - has been a goal of researchers and doctors for a long time. New research provides a way of delivering personalized treatments to patients with neurological disease.
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Image: woman working at a computer; Copyright: LA Cicero

Artificial intelligence helps predict drug combinations' side effects

13/07/2018

Last month alone, 23 percent of Americans took two or more prescription drugs, according to one CDC estimate, and 39 percent over age 65 take five or more, a number that's increased three-fold in the last several decades. And if that isn't surprising enough, try this one: in many cases, doctors have no idea what side effects might arise from adding another drug to a patient's personal pharmacy.
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Image: three brain scans of two different brains; Copyright: Lutz Jäncke, UZH

MRI reveals: Every person has a unique brain anatomy

12/07/2018

Like with fingerprints, no two people have the same brain anatomy, a study by researchers of the University of Zurich has shown. This uniqueness is the result of a combination of genetic factors and individual life experiences.
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Image: view out of an MRI at seven men looking into the camera; Copyright: Thor Balkhed

Blood flow in the heart revealed in a flash

12/07/2018

Researchers at Linköping University have for the first time been able to use information from computer tomography images to simulate the heart function of an individual patient. Some of the modelling methods they use have been developed in the motor industry.
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Image: look over the shoulder of a female researcher at a computer; Copyright: CRG

Big Data analysis identifies new cancer risk genes

11/07/2018

Researchers at the Centre for Genomic Regulation (CRG) in Barcelona developed a new method to systematically identify genes contributing to heritable cancer risk. Their work, which is published in Nature Communications, is a success story for data sharing and openness in science. Just three researchers identified new cancer genes only using publically available data.
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Image: left: test person with a kind of breathing mask on a training device, right: test person with electrode cap at the computer; Copyright: McGill University

Visualized: exercises creates optimal brain state

11/07/2018

If you want to learn to walk a tightrope, it's a good idea to go for a short run after each practice session. That’s because a recent study in NeuroImage demonstrates that exercise performed immediately after practicing a new motor skill improves its long-term retention.
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Image: four images of how the software works and identify potential spine locations; Copyright: Max Planck Florida Institute for Neuroscience

New software for rapid, automated identification of dendritic spines

10/07/2018

Is it possible for microscopes to learn a bit about the brain? Even be taught by neuroscientists to reliably recognize parts of brain cells - all on their own? Though it may seem like something straight out of The Jetsons, a neuroscientist and software engineer in the lab of MPFI's Scientific Director is developing new software with the goal of vastly improving the daily life of a microscope user.
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Image: CT and PET SUV images of both knees of an RA patient with clinical signs of synovitis, and a healthy control; Copyright: N Narayan et al. 2018, University of Oxford, Headington, Oxford, UK

Novel PET imaging to evaluate rheumatoid arthritis inflammation

10/07/2018

A new positron emission tomography (PET) imaging method more fully evaluates the extent of rheumatoid arthritis by targeting translocator protein (TSPO) expression in the synovium (joint lining tissue). The study is featured in the July issue of The Journal of Nuclear Medicine.
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Image: x-ray images; Copyright: Hojjat Salehinejad/MIMLab

Training artificial intelligence with artificial X-rays

09/07/2018

Artificial intelligence (AI) holds real potential for improving both the speed and accuracy of medical diagnostics. But before clinicians can harness the power of AI to identify conditions in images such as X-rays, they have to 'teach' the algorithms what to look for.
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Image: blurred doctor in the background uses keyboard in the foreground and writes something on a clipboard; Copyright: panthermedia.net/Ronalds Stikans

Model automates molecule design to speed drug development

09/07/2018

Designing new molecules for pharmaceuticals is primarily a manual, time-consuming process that's prone to error. But MIT researchers have now taken a step toward fully automating the design process, which could drastically speed things up - and produce better results.
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Image: Small brown mole on the back of a hand; Copyright: panthermedia.net/Mario Hahn

Early detection: Tattoo signals cancer – and more

09/07/2018

People who are not ill and do not show any symptoms typically do not visit the doctor. And while most people know that preventive medical checkups for cancer, for example, are important, they still avoid them. They tend to be very hesitant because the doctor might detect a serious illness. In the future, a new type of implant could make it easier to go to a screening test.
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Image: view inside the

A factory to go

06/07/2018

In the future, companies will be able to offer flexible production close to their customers. A fully automated production line can be housed inside a 20-foot ISO container, which a heavy truck can transport quickly to wherever it is needed. Medical products can be manufactured in close proximity to a hospital, for instance.
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Image: headset; Copyright: UTA

New headset scans the user's eye movements

06/07/2018

People with disabilities such as ALS, spinal injury or Lou Gehrig's disease, often lose use of their legs, arms or hands. Even at advanced stages of the disease, one may still retain movement in their eyes. Some technologies have incorporated eye-tracking to enable disabled persons to interact with a computer to communicate messages to a caregiver.
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Image: In vitro time course reflecting clinical evolution of cetuximab response and evolution of acquired resistance; Copyright: Johns Hopkins Kimmel Cancer Center

Computer algorithm maps cancer resistance to drugs

05/07/2018

New methods of studying the evolution of treatment resistance in head and neck cancer are being developed by researchers at the Johns Hopkins Kimmel Cancer Center. The scientists wanted to examine how cancers acquire resistance to treatment over time and whether those changes could be modeled computationally to determine patient-specific timelines of resistance.
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Image: girl with colorful scarf around her head; Copyright: panthermedia.net/frantab

New device may detect heart dysfunction in childhood cancer survivors

05/07/2018

A wireless device designed for detection of heart dysfunction in childhood cancer survivors treated with anthracycline chemotherapy was accurate and displayed a low false-negative rate as compared to cardiac magnetic resonance (CMR) imaging.
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Image: a kind of molecular map in pink and green made with the new technology; Copyright: Helmholtz Zentrum München

Innovative tissue analysis thanks to new imaging method

04/07/2018

A total of 200,000 euros has been granted to the spin-off project Theraselect. The Helmholtz Association and Helmholtz Zentrum München will each provide half the funding for the designated spin-off. The project centres around a mass spectrometry imaging method that makes thousands of molecules visible in tissue samples.
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Image: all-optical ultrasound imager; Copyright: Erwin J. Alles, University College London

Versatile ultrasound system could revolutionize medical imaging

04/07/2018

While ultrasound is one of the most common medical imaging tools, conventional electronic ultrasound devices tend to be bulky and cannot be used at the same time as some other imaging technologies. A new ultrasound system that uses optical, instead of electronic components, could improve performance while giving doctors significantly more flexibility in how they use ultrasound.
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Image: illustration of tiny walking

First-of-its-kind biofabrication research lab opens

03/07/2018

Enabled by a generous gift from the Roy J. Carver Charitable Trust, the BioMaker Lab at the Frederick Seitz Materials Research Lab (MRL) will be the first state-of-the-art interdisciplinary biofabrication hub in the world.
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Image: centrifuge with blood samples; Copyright: panthermedia.net/Kiyoshi Takahase Segundo

New $20 blood test to diagnose thousands of hepatitis B patients

03/07/2018

Researchers have developed an accurate diagnostic score that consists of inexpensive blood tests to identify patients who require immediate treatment against the deadly hepatitis B virus – which can lead to liver damage or cancer.
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Image: Signals from the electrically conductive hydrogel while someone is smiling or frowning; Copyright: KAUST

Electronic skin stretched to new limits

02/07/2018

A metal carbide within a hydrogel composite senses, stretches and heals like human skin for use in medicine and robotics.
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Image: open mouth with a plaster inside; Copyright: University of Sheffield

Biodegradable plaster will revolutionize treatment

02/07/2018

Scientists from the University of Sheffield's School of Clinical Dentistry, working in close collaboration with Dermtreat A/S from Copenhagen, have developed a unique patch using special polymers which are able to stick to moist surfaces.
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Photo: A HKU mechanical engineering team in front of their hydraulic-driven neurosurgical robotic system; Copyright: The University of Hong Kong

World's first intra-operative MRI-guided robot for bilateral stereotactic neurosurgery

29/06/2018

Stereotactic neurosurgery is one of the treatment to a variety of movement and neuropsychiatric disorders, s.a. Parkinson's disease, essential tremor and major depression. It involves a technique that can locate targets of surgical interest using an external positioning system, which is widely applied in brain biopsy, tumor ablation, drug delivery, as well as deep brain stimulation ("DBS").
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Photo: X-ray and MRI scan of a knee; Copyright: panthermedia.net/Bunyos30

Cell technology used to treat osteochondral knee defect

29/06/2018

A joint paper by Kazan Federal University and Tatarstan Republican Clinical Hospital appeared in Frontiers in Medicine. As the publication describes, autologous cells of stromal vascular fraction were transplanted to a 36-year-old man with the use of fibrin matrix. The patient, whose injury had been caused by a fall, then has been under supervision for 2 years.
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Graphic: Joint space in hip, knee and ankle joints as analyzed by the JSM algorithm; Copyright: Tom Turmezei

New 3D imaging analysis technique could lead to improved arthritis treatment

27/06/2018

An algorithm to monitor the joints of patients with arthritis, which could change the way that the severity of the condition is assessed, has been developed by a team of engineers, physicians and radiologists led by the University of Cambridge.
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Photo: Newborn in a hospital post-delivery room; Copyright: panthermedia.net/Naypong

Genomics offers new treatment options for infants with range of soft tissue tumors

27/06/2018

The genetic causes of a group of related infant cancers have been discovered by scientists at the Wellcome Sanger Institute, the University of Wuerzburg and their collaborators. Whole genome sequencing of tumours revealed mutations which are targetable by existing drugs used to treat lung cancer and melanoma.
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Image: scientists in the laboratory; Copyright: panthermedia.net/pressmaster

Predicting heart disease risk with gene editing technology

26/06/2018

Scientists may now be able to predict whether carrying a specific genetic variant increases a person's risk for disease using gene editing and stem cell technologies, according to new research in the American Heart Association's journal Circulation.
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Image: illustration of drug encapsulation; Copyright: Zheng Lab/Penn State

Camouflaged nanoparticles deliver killer protein to cancer

25/06/2018

A biomimetic nanosystem can deliver therapeutic proteins to selectively target cancerous tumors, according to a team of Penn State researchers. Using a protein toxin called gelonin from a plant found in the Himalayan mountains, the researchers caged the proteins in self-assembled metal-organic framework (MOF) nanoparticles to protect them from the body's immune system.
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Image: two hands holding a blood sugar measuring device; Copyright: panthermedia.net/WavebreakmediaMicro

Diabetes added to high risks for people with severe mental illness

22/06/2018

People with severe mental illness are more than twice as likely to have Type 2 diabetes, with even higher risks among patients who are African American or Hispanic, according to a new study led by UCSF.
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Image: proteins in the nuclear pore complex; Copyright: California Institute of Technology

How 'gatekeepers' to a cell's nucleus let genetic instructions pass through

22/06/2018

New structural details emerge about one of the body's biggest protein assemblages, the nuclear pore complex.
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Image: AcCellerator research device at an exhibition stand; Copyright: Daniel Klaue, ZELLMECHANIK DRESDEN GmbH

Cells in the speed trap – diagnosis in a matter of seconds

22/06/2018

A drop of blood provides a lot of valuable information. However, it takes several hours to analyze the blood of a patient and make a diagnosis. This takes away a lot of time that's crucial for treatment. A new method intends to considerably speed up this process by testing the cells in the blood in terms of their deformability and immune response.
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Image: young woman listening to music via head phones; Copyright: panthermedia.net/stokkete

Study finds music therapy brings effective pain relief

21/06/2018

New study from University Hospitals Connor Integrative Health Network published in the Journal of Music Therapy.
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Image: electron microscopy images confirm the deposition of an extracellular matrix; Copyright: University of Basel

Blood formation: researchers engineer human bone marrow tissue

21/06/2018

Researchers have developed an artificial tissue in which human blood stem cells remain functional for a prolonged period of time. Scientists from the University of Basel, University Hospital Basel, and ETH Zurich have reported their findings in the scientific journal PNAS.
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Image: a woman standing on a scale saying

Study offers new hope for the fight against genetically determined obesity

20/06/2018

Around two to six per cent of all people with obesity develop obesity already in early childhood; it's in their genetic cards. Obesity-causal mutations in one of their "appetite genes" gives them a strong genetic predisposition for developing obesity, also called monogenic obesity. Their experience of hunger is overruling and their feeling of satiety limited.
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Image: young man sleeping, his head resting on the table; Copyright: panthermedia.net/MichalLudwiczak

UA study links sleep loss with nighttime snacking

20/06/2018

The study found poor sleep quality was associated with nighttime snacking and a high likelihood of craving junk food. The study also found that junk food cravings were associated with increased risk of obesity, diabetes and other health problems.
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Image: young woman in front of a laptop, looking tired; Copyright: panthermedia.net/SIphotography

Why do some sleep-deprived people experience worse cognitive functioning than others?

19/06/2018

Penn study reveals that microRNAs predict differences in cognitive impairment in memory and attention after sleep deprivation.
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Image: nurse holding a brown dog in her arms; Copyright: Michael Bernkopf/Vetmeduni Vienna

Immunoglobulin E as a promising new form of anti-cancer immunotherapy

19/06/2018

If immunoglobulin E (IgE) antibodies are directed against harmless antigens such as pollen, the result can be an allergic reaction. However the original purpose of these IgE antibodies is to repel harmful exogenous substances rather than to trigger allergies.
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Image: left: mouse waiting for a reward for a short time; right: mouse waiting for a long time ; Copyright: OIST

Wait for it: Serotonin and confidence at the root of patience

18/06/2018

Serotonin keeps mice hanging on if they are sure of getting rewards, but not sure when.
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Image: S100A8/S100A9 protein complex (grey/beige) binds to the TLR4 receptor (rainbow-coloured) and MD2 (red); Copyright: Vogl et al./ J. Clin. Invest.

Münster researchers have discovered a possible new treatment for regulating inflammation

18/06/2018

Researchers at the Cells-in-Motion Cluster of Excellence have decoded a mechanism found at the beginning of almost every inflammatory response. Their study provides a new approach to develop novel treatment options for many inflammatory disorders with many fewer side effects compared to current drugs.
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Image: illustration of an eye ball affected by diabetic retinopathy; Copyright: panthermedia.net/megija

New pharmacological treatment against diabetic eye diseases is tested

15/06/2018

The so called "diabetic retinopathy" and the "diabetic macular edema" are two of the most frequent ocular diseases in patients with diabetes, and both feature pathologic changes of blood vessel functions in the retina. Experimental data and measurements in patients suggest that these changes in blood vessel functions may originate from a lack of vasoinhibin hormones in the retina.
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Image: illustration of an eye ball affected by diabetic retinopathy; Copyright: panthermedia.net/megija

Tuberculosis: clinical trials on a newly developed drug initiated

15/06/2018

The first antibiotic against tuberculosis that has been developed in Germany is now ready for clinical testing. BTZ043, as the newly developed drug substance is called, is also effective against multidrug-resistant pathogens which are increasingly challenging successful treatment worldwide.
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Image: scientist in the laboratory; Copyright: 2018 KAUST

The long and the short of DNA replication

14/06/2018

An unexpectedtwo-step mechanism occurs when cells copy DNA.
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Image: Emerging platelets (white arrows) are buded off by their progenitor cells, the megakaryocytes; Copyright: Rudolf Virchow Center of the Julius-Maximilians-Universität Würzburg

Targeting platelets

13/06/2018

A new Collaborative Research Center will start in July with a total funding of nearly 14 million euros, headed by the German Institute for Experimental Biomedicine in Würzburg. The aim is to decode the complex and insufficiently understood functions of platelets, the so-called thrombocytes.
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Image: plastic heart with a stethoscope; Copyright: panthermedia.net/shidlovski

'Multiomics' and the mouse heart - New insights into the development of heart disease therapeutics

13/06/2018

The heart of a neonatal mouse is capable of self-repair after tissue damage. However, this ability disappears during the first week of life. Researchers at the University of Helsinki investigate the molecular mechanisms underlying myocardial regenerative ability.
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Image: measles virus under the microscope; Copyright: Cynthia S. Goldsmith; William Bellini / CDC

Transmission of measles virus: Interaction with two cell receptors is required

12/06/2018

Researchers at the Paul-Ehrlich-Institut have reproduced measles virus transmission in an animal model. They were able to show that an efficient interaction with two cellular receptors plays a decisive role in the efficient transmission of the virus.
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Image: mountain tops covered in snow; Copyright: Dr. Daniela Flueck, University of British Columbia Okanagan

Scientists discover why heart function is reduced at high altitude

12/06/2018

For over a century, we have known that high altitude reduces the amount of blood the heart pumps around the body with each beat. New research published in The Journal of Physiology has unearthed why this is the case and the findings will be important for people who live, travel and exercise at high altitudes.
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Image: middle-aged woman drinking alcohol; Copyright: panthermedia.net/Kzenon

How does alcohol influence the development of Alzheimer's disease?

11/06/2018

Research from the University of Illinois at Chicago has found that some of the genes affected by alcohol and inflammation are also implicated in processes that clear amyloid beta - the protein that forms globs of plaques in the brain and which contributes to neuronal damage and the cognitive impairment associated with Alzheimer's disease.
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Image: histological image of colon sections from mice that received T cells from CD4-creERafl/fl mice; Copyright: University of Turku

Estrogen and T cell immune response linked to autoimmune inflammation

11/06/2018

Women are more prone to the development of autoimmune diseases. The female hormone estrogen is likely to affect the immune system. A team of scientists from Turku Center for Biotechnology and University of Georgia reported new findings related to the involvement of estrogen hormone receptor in autoimmune diseases.
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Image: collagen from a healthy engineered lung tissue; Copyright: Ruogang Zhao

Lung-on-a-chip simulates pulmonary fibrosis

08/06/2018

Developing new medicines to treat pulmonary fibrosis, one of the most common and serious forms of lung disease, is not easy. One reason: it's difficult to mimic how the disease damages and scars lung tissue over time, often forcing scientists to employ a hodgepodge of time-consuming and costly techniques to assess the effectiveness of potential treatments.
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Image: a woman shows how to use the device by holding it in front of the eyes of a young woman; Copyright: Nick Romanenko / Rutgers University

Portable device promises faster, more accessible schizophrenia diagnosis

08/06/2018

A common in optometrists' offices may hold the key to faster diagnosis of schizophrenia, predicting relapse and symptom severity and assessing treatment effectiveness, a Rutgers University study finds.
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Image: Professor Dougu Nam and his research team in the School of Life Sciences at UNIST; Copyright: UNIST

New method for finding disease-susceptibility genes

07/06/2018

A new study, affiliated with UNIST has recently presented a novel statistical algorithm, capable of identifying potential disease genes in a more accurate and cost-effective way. This algorithm has also been considered as a new promising approach for the identification of candidate disease genes, as it works effectively with less genomic data and takes only a minute or two to get results.
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Image: two MRI scans of a heart; Copyright: Imperial College of London

New link found between alcohol, genes and heart failure

07/06/2018

The researchers investigated faulty versions of a gene called titin which are carried by one in 100 people or 600,000 people in the UK. Titin is crucial for maintaining the elasticity of the heart muscle, and faulty versions are linked to a type of heart failure called dilated cardiomyopathy.
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Image: renal denervation system; Copyright: ReCor Medical, Inc.

Surgery involving ultrasound energy found to treat high blood pressure

06/06/2018

An operation that targets the nerves connected to the kidney has been found to significantly reduce blood pressure in patients with hypertension, according to the results of a clinical trial led in the UK by Queen Mary University of London and Barts Health NHS Trust, and supported by the National Institute for Health Research (NIHR).
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Image: Dr. Sonia Lippke; Copyright: Jonas Ginter / WFB

Sleep quality influences performance more than sleep quantity

06/06/2018

A healthy, low-fat diet and undisturbed sleep play an important role in remaining fit and full of energy during the day. Sleep quantity, on the other hand, is of less importance. This is the finding of a recently published study in the journal Health Behavior & Policy Review, which was conducted at Jacobs University Bremen.
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Image: Microscopic colour image showing cells with normal (green dots) and abnormal (yellow dots) stress granules; Copyright: Team Buchberger

The big clean up after stress

05/06/2018

When cells become stressed, they activate specific response patterns. Würzburg researchers have identified new details of these responses, which can help to get a better understanding of neurodegenerative diseases.
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Image: 3D structure of the enzymatic active part of SdeA toxin; Copyright: Nature/Kalayil et al

Complementing conventional antibiotics

05/06/2018

Antimicrobial resistance is a major medical problem worldwide, impacting both human health and economic well-being. A new strategy for fighting bacteria has now been reported in the latest online issue of Nature by a research group headed by Prof. Dikic at the Goethe University Frankfurt. The scientists revealed the molecular action mechanism of a Legionella toxin and developed a first inhibitor.
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Image: illustration of two mice, one with a walking stick; Copyright: Kerstin Wagner / FLI

Less is more? Gene switch for healthy aging found

04/06/2018

Aging is associated with an increase in frailty and age related-diseases. A calorie-restricted diet is known to alleviate these age-related conditions. Researchers from the ERIBA in Groningen, Netherlands, and the FLI in Jena, Germany, now demonstrate in a mouse model that the C/EBPß-LIP gene regulator is involved in the aging process.
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Image: needle, urine sample and blood sample; Copyright: Christian Urban, Kiel University

Cancer diagnosis: no more needles?

04/06/2018

Urine is an everyday liquid which most people pay little attention to and regard as rather unpleasant. It’s quite the opposite for a group of clinical researchers from Kiel University, the University Medical Center Schleswig-Holstein (UKSH) and the Lithuanian University of Health Sciences in Kaunas, who are convinced of the diagnostic potential of this yellowish liquid.
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Image: pregnant woman wearing a light pink shirt; Copyright: panthermedia.net/EugeneGensyurovksy

Vast majority of poor, urban women don't use prenatal vitamins

01/06/2018

A study of more than 7,000 low-income, urban mothers enrolled in the Boston Birth Cohort found that fewer than 5 percent of them started folic acid supplementation and used it almost daily before pregnancy, a widely recommended public health measure designed to prevent potentially crippling birth defects.
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Image: transparent human torso, kidney highlighted in red; Copyright: panthermedia.net/sciencepics

CU researchers offer insights into liver disease caused by intravenous nutrition

01/06/2018

Research by physician-scientists at the University of Colorado Anschutz Medical Campus offers hope for improved quality of life for people who rely on intravenous nutrition due to intestinal damage.
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Image: illustration showing the temperatures in a car parked in the sun; Copyright: Safwat Saleem/ASU

Hot cars can hit deadly temperatures in as little as one hour

31/05/2018

A lot can happen at 160 degrees Fahrenheit: Eggs fry, salmonella bacteria dies, and human skin will suffer third-degree burns.
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Image: blood vessel and red blood cells; Copyright: panthermedia.net/the_lightwriter

The vessel not taken: understanding disproportionate blood flow

31/05/2018

Considering the size of red blood cells, a new model for blood flow sheds light on why blood sometimes prefers some vessels over others.
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Image: a group of young people next to social media symbols and icons; Copyright: panthermedia.net/WavebreakmediaMicro

Social media usage linked to underage drinking

30/05/2018

Penn Medicine research explores adolescent and young adult social media use and drinking patterns.
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Image: skeletal myoblast cells in rats; Copyright: Yuge Lab

Space-like gravity weakens biochemical signals in muscle formation

30/05/2018

Microgravity conditions affect DNA methylation of muscle cells, slowing their differentiation.
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Image: Yune Lee; Copyright: The Ohio State University

Subtle hearing loss while young changes brain function, study finds

29/05/2018

Early damage could open door to dementia, lead author says.
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Image: Worldwide expansion of the two invasive mosquito species a) Asian tiger mosquito (Aedes albopictus) and b) yellow fever mosquito (Aedes aegypti); Copyright: Dorian D. Dörge (Goethe University)

Asian tiger mosquito on the move

28/05/2018

Invasion has a long tradition and is being accelerated by globalisation, trade and tourism.
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Image: chemical structure of furanosteroids-Structures of wortmannin and viridin; Copyright: The University of Tokyo

Identification of biosynthetic pathway for the steroids with phosphatidylinositol 3-kinase inhibition activity

25/05/2018

A group of researchers from Graduate School of Pharmaceutical Sciences at The University of Tokyo and Institute of Traditional Chinese Medicine and Natural Products at Jinan University, identified the biosynthetic gene cluster for the furanosteroid demethoxyviridin, and deciphered its biosynthetic pathway.
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Image: semaphorin 6D reverse signaling controls lipid metabolism and anti-inflammatory polarization; Copyright: Osaka University

Neuron guidance factor found to play a key role in immune cell function

25/05/2018

Macrophages are white blood cells involved in a variety of biological functions, from destroying infectious pathogens to repairing damaged tissue. To carry out their different roles, macrophages must first be activated and transformed into different subtypes. However, the mechanisms that lead to macrophage activation are not fully understood.
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Image: illustration of DNA strings; Copyright: pixabay.com

The dark side of our genes – healthy ageing in modern times

24/05/2018

The transition to modernity – largely driven by the Industrial Revolution – provided us with easier access to food and clean water, with antibiotics, vaccines, and modern medicine. Yet modernity did not just bring fewer infectious diseases and longer life: it also created an environment radically different from the one we evolved in.
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Image: network of protein fibrills; Copyright: Claessens

Parkinson-related protein is 'tunable'

24/05/2018

Fibrils of the protein alpha-synuclein, that plays a role in Parkinson's disease, form a stiffer and stronger network in water, when temperature is increased. Researchers of the University of Twente show that this has to do with the water-repellent part of the fibres coming to the surface and interacting.
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Image: man holding his stomach; Copyright: panthermedia.net/ByLove

The cure is in the capsule: carbon monoxide to treat chronic inflammation

22/05/2018

This unusual ally can be extremely valuable in the fight against inflammation in the body: CO (carbon monoxide). As a therapeutic gas, it also promises relief for inflammatory gastrointestinal diseases. Having said that, it is difficult to transport the active ingredient to the exact desired location.
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Image: Image from a confocal microscope showing so-called pin-wheel structure of the lateral wall of the lateral ventricle; Copyright: Helmholtz Zentrum München

Everything flows: cerebrospinal fluid regulates neural stem cell division

22/05/2018

Stem cells in the brain can divide and mature into neurons participating in various brain functions, including memory. In a paper published in the journal Cell Stem Cell, scientists at Helmholtz Zentrum München and Ludwig-Maximilians-Universität München have shown how this works. They found that ion channels play a key role in mediating force signals to the neural stem cells to activate them.
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Image: pair of legs during walking; Copyright: IStock

You walk talks

22/05/2018

The way you walk can reveal current and future health problems. New research from Halmstad University suggests the use of wearable sensors for analysing your movement. This can potentially result in early detection of for example Parkinson's disease, dementia, multiple sclerosis and other neuro-physiological disorders.
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Image: Illustration of lung structure from CT scan data; Copyright: University of Southampton

How the power of mathematics can help assess lung function

21/05/2018

Researchers at the University of Southampton have developed a new computational way of analysing X-ray images of lungs, which could herald a breakthrough in the diagnosis and assessment of Chronic Obstructive Pulmonary Disease (COPD) and other lung diseases.
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Image: A simple protocol developed for insulin preparation; Copyright: Michio Iwaoka

High efficiency synthesis of insulin by self-assembly based organic chemistry

21/05/2018

Researchers at Tokai, Osaka, Tohoku and Fukuoka Universities report in the journal Communications Chemistry on the synthesis of insulin based on the self-assembly of polypeptide chains at about 40% efficiency.
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Image: PET scan showing clumping proteins in rat hearts (top). The enlarged heart (right) is one with heart failure. Other PET scans showing blood flow; Copyright: Circulation Research, May 11, 2018

Heart failure: The Alzheimer's disease of the heart?

18/05/2018

Protein clumping may contribute to heart failure development and could be used as a diagnostic tool for testing therapies or disease progression.
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Image: Clusters of MAIT cells in human blood and colon biopsies; Copyright: Department of Biomedicine, Tobias Rutishauser; Copyright: University of Basel

Human MAIT cells sense the metabolic state of enteric bacteria

18/05/2018

A little-explored group of immune cells plays an important role in the regulation of intestinal bacteria. Changing metabolic states of the microbes have an effect on defense cells at different stages of alert or rest, as researchers from the Department of Biomedicine at the University and University Hospital of Basel report in the journal Mucosal Immunology.
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Image: smiling young woman - Laura Volpicelli-Daley; Copyright: UAB

Untangling brain neuron dysfunction in Parkinson's disease and dementia with Lewy bodies

17/05/2018

A neuron model of Parkinson's disease and Lewy body dementias shows defects that could suggest treatments to halt or reverse cognitive impairments before the neurons die.
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Image: wooden spoon with fish oil pills; Copyright: panthermedia.net/sommaill

Symptoms of osteoarthritis lessened with simple changes to the diet

17/05/2018

One gram of fish oil a day could help reduce the pain of patients with osteoarthritis, a new study in Rheumatology reports.
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Image: blood vessel with red and white blood cells; Copyright: panthermedia.net/vampy1

New insights into blood vessel growth

16/05/2018

Scientists at the Goethe University have discovered that single cells in the innermost layer of blood vessels proliferate after injury and in so doing make a significant contribution to the formation of new vessels.
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Image: woman who has fallen asleep in front of a computer during her night shift; Copyright: panthermedia.net/sakkmesterke

The effect of night shifts: gene expression fails to adapt to new sleep patterns

16/05/2018

Have you ever considered that working night shifts may, in the long run, have an impact on your health? A team of researchers from the McGill University affiliated Douglas Mental Health University Institute (DMHUI) has discovered that genes regulating important biological processes are incapable of adapting to new sleeping and eating patterns.
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Image: smiling young woman - Megha Padi, Ph.D., director of the UA Cancer Center Bioinformatics Shared Resource; Copyright: University of Arizona Health Sciences/BioCommunications

Unlocking cancer's secrets using the 'social networks' of cells

14/05/2018

Megha Padi, Ph.D., of the UA Cancer Center has developed a method for probing the genetic underpinnings of cancer and other diseases, which could lead to better treatments.
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Image: scientist holding up a test tube containing a pink liquid; Copyright: Medical University of Vienna

Combating cancer and infectious diseases with natural milk protein

14/05/2018

Researchers from the Institute for Hygiene and Applied Immunology of the Center for Pathophysiology, Infectology and Immunology at MedUni Vienna, led by Hannes Stockinger, have discovered a hitherto unknown function of the protein lactoferrin, which is primarily found in breast milk.
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Image: Tahir Hussain in the laboratory; Copyright: Kris Kehe/UH College of Pharmacy

Protecting kidneys from obesity

11/05/2018

UH professor of pharmacology Tahir Hussain has received $1.6M from the National Institutes of Health to examine a kidney cell that could prevent damage from inflammation caused by obesity. The targeted cells express a protein called the angiotensin type 2 receptor (AT2R), which recently has been indicated to have anti-inflammatory and reno protective actions.
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Image: information on prescribing patterns within peer distribution; Copyright: Kirsty Challen, Lancashire Teaching Hospitals, UK

Providing clinicians feedback on their opioid prescribing data alters future prescribing

11/05/2018

Asking emergency department (ED) providers to self-identify their opioid prescribing practices and then providing them with timely, clinically relevant, individualized, and actionable feedback on their actual opioid prescribing data, significantly decreases future opioid prescribing among providers who underestimate their baseline prescribing.
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Image: chemical structure in shape of an octopus; Copyright: Georgia Tech / Wu / Xiao & NYPL Digital Commons / Brumfield

Chemical octopus catches sneaky cancer clues, trace glycoproteins

10/05/2018

Cancer drops sparse chemical hints of its presence early on, but unfortunately, many of them are in a class of biochemicals that could not be detected thoroughly, until now. Researchers at the Georgia Institute of Technology have engineered a chemical trap that exhaustively catches what are called glycoproteins, including minuscule traces that have previously escaped detection.
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Image: Khodayar Rais-Bahrami with a text about the press release; Copyright: Children's National Health System

COstatus monitor provides direct measure of neonates' cardiac output

10/05/2018

Clinicians caring for vulnerable babies in the neonatal intensive care unit (NICU) need to closely monitor their vital signs, but precisely gauging the function of their tiny hearts has remained elusive.
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Image: two walnuts, one of it half open; Copyright: panthermedia.net/Dionisvera

Walnuts impact gut microbiome and improve health

09/05/2018

Diets rich in nuts, such as walnuts, have been shown to play a role in heart health and in reducing colorectal cancer. According to a new study from the University of Illinois, the way walnuts impact the gut microbiome – the collection of trillions of microbes or bacteria in the gastrointestinal tract – may be behind some of those health benefits.
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Image: Karen Fratantoni with a text about the press release; Copyright: Children's National Health System

Depression among parents of newborns can persist after NICU discharge

09/05/2018

Young parents who have less education and care for more than one child are more likely to have persistent symptoms of depression that linger six months after their newborn is discharged from the neonatal intensive care unit (NICU), according to a Children's National Health System research presentation during the Pediatric Academic Societies 2018 annual meeting.
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Image: binding of nNOS to the protein NOS1AP; Copyright: University of Turku

New approach for treating neuropathic pain

08/05/2018

Neuropathic pain is the chronic, pathological pain that continues even when the cause of pain is removed. Causes include damage to nerve cells and medicines used to treat cancer. A collaboration between research groups from USA and Finland has discovered a novel therapeutic that appears to interrupt the signaling cascades in the body required for multiple forms of neuropathic pain.
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Image: Drs. Babak Baban (from left), Jack Yu and Jatinder Bhatia in the Children's Hospital of Georgia's NICU; Copyright: Phil Jones, Senior Photographer, Augusta University

SWAT team of immune cells found in mother's milk

08/05/2018

Immune cells that are ready to take action against invaders like bacteria have been found in women's breast milk, researchers say. They say the presence of this SWAT team of immune cells called innate lymphoid cells, or ILCs, in human breast milk is more evidence of the benefits of breastfeeding.
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Image: two men in the laboratory next to the Organ Care System with a pig's lung inside; Copyright: Kaiser/MHH

Organ Care System: treatment under extreme conditions

08/05/2018

Multidrug-resistant organisms that are treated with a dosage that exceeds the regular dose a hundred times and at temperatures of over 40 degrees Celsius – the human organism is unable to handle it. Yet if the diseased organ is treated outside of the body, extreme conditions are an option. For the first time, physicians have succeeded in treating a severe case of pneumonia by using the OCS.
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Image: map of the US showing varying rates of identification, including underrepresentation, of autism for minority groups in 2014; Copyright: Jason Travers, Exceptional Children

Study shows minorities widely underrepresented in autism diagnoses

07/05/2018

In education circles, it is widely accepted that minorities are overrepresented in special education. New research from the University of Kansas has found, in terms of autism, minorities are widely underrepresented in special education.
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Image: chemical diagram representing the new compound JVW-1034; Copyright: James Sahn/University of Texas at Austin

Anti-alcoholism drug shows promise

07/05/2018

Scientists at The University of Texas at Austin have successfully tested in animals a drug that, they say, may one day help block the withdrawal symptoms and cravings that incessantly coax people with alcoholism to drink. If eventually brought to market, it could help the more than 15 million Americans, and many more around the world who suffer from alcoholism stay sober.
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Image: young woman holding her head, with a sad expression on her face and black lines emerging from her head; Copyright: panthermedia.net/SIphotography

Understanding fear of guilt key in better treating OCD

04/05/2018

Advances in our understanding of the development and persistence of Obsessive-Compulsive Disorder (OCD) have the potential to improve treatment according to a new study by the University of Waterloo.
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Image: smiling man in an office - Subhrangsu Mandal, UTA associate professor of chemistry; Copyright: UTA

UTA researchers investigate link between ovarian hormones and blood cholesterol levels

04/05/2018

Results may open new avenues for treating cardiovascular disease.
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Image: Three-dimensional structures of nicotinic acetylcholine receptor; Copyright: Hibbs Lab, UT Southwestern Medical Center

Cryo-EM structures of the nicotine receptor may lead to new therapies for addiction

03/05/2018

UT Southwestern researchers today published in Nature atomic-scale blueprints of the most abundant class of brain nicotinic acetylcholine receptors. A structural understanding of the protein, found in neurons, could lead to new ways to treat nicotine addiction from smoking and vaping.
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Image: vessels of the retina; Copyright: Michael Chiang/OHSU

AI better than most human experts at detecting cause of preemie blindness

03/05/2018

New algorithm could help overcome shortage of physicians trained in disease diagnosis.
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Image: Woman is standing on a 3D scanner that measures her feet; Copyright: panthermedia.net/roman023

Biomechanical measuring systems: Versatile tools for many disciplines

02/05/2018

When human movements are no longer as smooth as they should be – due to misalignments or as the result of an injury for example – biomechanical measuring systems spring into action. Thanks to different types of sensors and optical technologies, physicians, therapists, and sports scientists embark on a search for possible causes and corrective options.
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Image: Hepatocyte-like cells (HLCs) differentiated from the stem cells of patients with hemophilia B show very low levels of clotting factor IX, or FIX, shown in white; Copyright: Salk Institute

Single injection treats hemophilia B for life, in proof-of-concept study

02/05/2018

For most people with hemophilia B, whose bodies can't properly form blood clots, constant injections to replenish their clotting factors are a way of life.
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Image: human eye, focus on the retina; Copyright: panthermedia.net/hquality

Strategy prevents blindness in mice with retinal degeneration

02/05/2018

More than 2 million people worldwide live with inherited and untreatable retinal conditions, including retinitis pigmentosa, which slowly erodes vision.
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Image: ocean view; Copyright: Sarah Bird/Michigan Tech

Meditation could help anxiety and cardiovascular health

27/04/2018

It sounds like a late-night commercial: In just one hour you can reduce your anxiety levels and some heart health risk factors. But a recent study with 14 participants shows preliminary data that even a single session of meditation can have cardiovascular and psychological benefits for adults with mild to moderate anxiety.
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Image: image of a retina; Copyright: Centre for Vision Research, the Westmead Institute for Medical Research

Eyes of adolescents could reveal risk of cardiovascular disease

27/04/2018

New research has found that poorer well-being or 'health-related quality of life' (HRQoL) in adolescence could be an indicator of future cardiovascular disease risk.
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Image: woman with scarf around her head and a girl sitting smiling on a sofa; Copyright: panthermedia.net/photographee.eu

Novel discoveries on aggressive NK-cell leukemia

26/04/2018

International research consortium led by researchers from the University of Helsinki, Finland, discovered new information related to a rare form of leukemia called aggressive NK-cell leukemia. Potential new treatment options were found which are highly warranted as currently this disease usually leads to rapid death of patients. The study was published in Nature Communications.
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Image: Florescent cells in the prelimbic prefrontal cortex brain regions, with inset; Copyright: Andrew Moberly, Perelman School of Medicine, University of Pennsylvania

Fight, flight, or freeze

26/04/2018

"Take a deep breath" is the mantra of every anxiety-reducing advice list ever written. And for good reason. There's increasing physiological evidence connecting breathing patterns with the brain regions that control mood and emotion.
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Image: illustration of equal and unequal crossovers during meiosis; Copyright: University of Rochester illustration / Michael Osadciw

Gene controlling genetic recombination rates

25/04/2018

Genetics is a crapshoot. During sexual reproduction, genes from both the mother and the father mix and mingle to produce a genetic combination unique to each offspring. In most cases, the chromosomes line up properly and crossover. In some unlucky cases, "selfish DNA" enters the mix, causing abnormal crossovers with deletions or insertions in chromosomes, which can manifest as birth defects.
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Image: fish counter; Copyright: Chalmers University of Technology

Eating more fish could prevent Parkinson's disease

25/04/2018

A new study from Chalmers University of Technology, Sweden, shines more light on the link between consumption of fish and better long-term neurological health. Parvalbumin, a protein found in great quantities in several different fish species, has been shown to help prevent the formation of certain protein structures closely associated with Parkinson's disease.
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Image: woman who cleans her nose among flowers; Copyright: Fotolia

Our genes dictate who develops an allergy

24/04/2018

Whether or not you develop an allergy is largely dependent upon genetic factors. This is the main finding of a study recently published in EBioMedicine, just in time for World Allergy Week (22-28. April 2018). The study was supervision of Winfried F. Pickl from MedUni Vienna's Institute of Immunology.
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Image: bright colours that flow into each other: illustration of EMT; Copyright: Université libre de Bruxelles

Cancer: Tumor transition states

24/04/2018

Tumor heterogeneity describes the differences between different cells within a given tumor. These differences have major implications for the diagnosis, prognosis, and therapy of cancer patients. Different mechanisms have been proposed to account for tumor heterogeneity such as epithelial to mesenchymal transition (EMT).
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Image: Two hands are holding a tubular frame that is carrying a glistening wet, white tube; Copyright: Leibniz University of Hanover/Institute of Technical Chemistry

Tissue engineering: how to grow a bypass

23/04/2018

A bypass is a complicated structure. It is either made of synthetic materials that can cause blood clots and infections or created by using the patient’s veins. However, the latter often does not yield adequate material. A newly developed bioreactor could solve this problem in the future. It is designed to tissue engineer vascular grafts by using the body’s own material.
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Image: toddler who gets vaccinated in the arms of a nurse; Copyright: panthermedia.net/evgenyataman

European Immunization Week 2018 – the right to be protected or the duty to protect?

23/04/2018

The European Immunization Week's general slogan "Prevent. Protect. Immunize" is more relevant than ever in times of globalization and migration. It is a political and structural challenge to give as many people as possible access to vaccination. But even the best care is of no use if the individual does not recognize his or her duty to society.
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Image: two men in the laboratory, one sitting at a microscope or similar, another standing behind him; Copyright: RUB, Kramer

Cancer drug observed at work

23/04/2018

Using a Raman microscope, researchers at Ruhr-Universität Bochum have studied at which targets the cancer drug Neratinib binds in cells and how its chemical structure changes. Compared with other techniques, this method offers a considerable advantage, as it is not necessary to apply a label to the drug that would indicate its distribution indirectly; rather, the drug itself can be monitored.
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Image: Mouse cells with (left) or without (right) DOR protein in green and blue ob black ground; Copyright: M. Romero, IRB Barcelona

DOR protein deficiency favours the development of obesity

23/04/2018

Obesity is a world health problem since excessive accumulation of fat tissue (or adipose tissue) increases the risk of cardiovascular disease, hypertension, diabetes and some types of cancer. However, some obese individuals are less susceptible to these conditions.
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Image: Abnormally activated astrocytes were accumulated in the lesion of ALS mouse without TRIF signaling; Copyright: Koji Yamanaka

Innate immune adaptor TRIF confers neuroprotection in ALS mice by eliminating abnormal glial cells

20/04/2018

Researchers led by Nagoya University revealed that deficiency of the innate immune adaptor TRIF significantly shortened survival time of ALS mice.
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Image: photo of photosensitizer conjugate; Copyright: Lobachevsky University

New highly selective antitumor photodynamic therapy agents synthesized

20/04/2018

This project is a result of collaboration of the Organic Chemistry Department and the Biophysics Department at the Lobachevsky University with the Research Institute of Macroheterocyclic Compounds.
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Image: DermaFC developed by Magnosco; Copyright: Magnosco

A startup makes melanin glow: skin cancer diagnostics with Magnosco

09/04/2018

When a skin lesion is suspected to exhibit malignant changes, it is usually promptly removed. However, not all cases require an excision of the affected tissue. The startup company Magnosco has developed a procedure that uses a laser to support the diagnosis and early detection of malignant melanoma.
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Image: young woman with VR-glasses in the VR-Lab, in front of it a young man at a computer, on which a virtual heart can be seen; Copyright: Kompetenzzentrum eLearning in der Medizin Baden-Württemberg

VR Lab for medical students: linking theory and practice

22/03/2018

Virtual reality and medicine are increasingly mentioned in the same context. In addition to the development of applications that support the treatment of patients suffering from chronic pain and anxiety, this technology also benefits medical staff. Two months ago, the Ulm University Hospital has opened the VR Lab, where medical students can train and learn with the help of 3D organs.
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Image: Young female radiologist is looking at pictures of the head and takes some notes; Copyright: panthermedia.net/mark@rocketclips.com

Radiology: machine learning to support medical diagnostics

08/03/2018

Automation makes work life easier in many ways but is it also a solution for analyzing medical images? Is a computer actually reliable enough to assist in the medical decision making process? Researchers in Landshut examine how machine learning algorithms can work more reliably and support radiologists.
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Image: Three men in suits and a woman in a laboratory coat are standing in a laboratory; Copyright: Ministry of Economy of Mecklenburg-Hither Pomerania/Norbert Fellechner

On the trail of cancer: personalized cancer vaccine

01/03/2018

Conventional cancer treatment selection typically depends on the location of the tumor. However, this approach ignores the distinct gene mutations in the tumor of the individual patient. New cancer research approaches increasingly emphasize the concept of personalized therapy.
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Image: A group of physicians is holding large colorful puzzle pieces in their hands and is putting them together; Copyright: panthermedia.net/Andriy Popov

Personalized medicine: a paradigm shift is gaining momentum

01/03/2018

Personalized medicine does not follow a "one-size-fits-all" treatment approach but emphasizes a "tailor-made" paradigm, meaning a treatment is customized to each individual person's case. For patients, this increases the chances of treatment success and means fewer side effects. While the approach originates in the field of oncology, it is now also increasingly applied to other disease patterns.
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Image: yellow tape measure with capsules in front of it; Copyright: panthermedia.net/Jiri Hera

Personalized cancer medicine: customized treatment

01/03/2018

Everyone is different. This statement also applies to our health. Cancer, in particular, can look and progress differently depending on the individual person. That’s why every patient ideally also needs a customized treatment that is tailored to their individual needs. But how feasible is this idea?
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Image: a container with the nutrient medium for cancer cells; Copyright: Dr. Markus Wehland

Cells in space – extraterrestrial approaches in cancer research

22/02/2018

Here on Earth, all experiments are bound by gravitation. Yet, freed from gravity's grip, tumor cells, for example, behave in an entirely different way. As part of the "Thyroid Cancer Cells in Space" project by the University of Magdeburg, smartphone-sized containers carrying poorly differentiated thyroid cancer cells are sent into space.
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Image: Photograph of hands with hyperspectral imaging; Copyright: Diaspective Vision GmbH

Precision surgery thanks to informative hyperspectral imaging

08/02/2018

When body tissue is reconnected during a tumor operation in the gastrointestinal tract, surgeons need information about the current state of these so-called anastomoses. The new, non-invasive hyperspectral imaging technology now makes it possible to measure the crucial parameters during surgery and thereby increase surgical precision.
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Image: Young female student is sitting between shelves on the floor of a library and reads; Copyright: panthermedia.net/Brock Jones

Patient science: patients research cystic fibrosis

22/01/2018

Research does not always occur in laboratory settings. As part of citizen science, citizens collect data and make it available for research projects. Now, this approach is also adopted in medicine by way of patient science: in a new project, patients take part in cystic fibrosis research. The goal is to improve the lives of those who are affected by this chronic disease.
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"Spray-On" muscle fibers for biomimetic surfaces

08/01/2018

Few patients with heart failure are fortunate enough to receive a donor's heart. Ventricular assist devices (or heart pumps) have been around for several years and are designed to buy time as patients wait for a transplant. Unfortunately, the body doesn't always tolerate these devices.
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Image: OR with very modern equipment; Copyright; Swen Reichhold

OR of the future: Surgical navigation systems and integrated devices

04/01/2018

While it is commonplace for operating room staff to work together as a team, the collaboration of operating room systems does not always work so well – many devices are still separated from one another, causing the OR processes to be prone to mistakes. The same applies to surgical navigation technologies that represent the interface between imaging, the surgeon and therapeutic devices.
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Image: Woman holding a doll in a glowing pyjamas; Copyright: Empa

Illuminated pyjamas treat jaundice in mommy's arms

20/12/2017

Sixty percent of newborns are affected by jaundice during their first days of life. In most cases, the condition is harmless. The ailment is more pronounced in premature babies, whose treatment involves irradiation with blue light in a special incubator – naked and alone.
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Image: forearm bone which is scanned in the ultrasound hand scanner; Copyright: Fraunhofer IBMT

Using ultrasound for verification: proof of legal age via handheld scanner

22/11/2017

Human trafficking is a global crime that often preys on underage persons and forces them into prostitution and forced labor. In most cases, people are smuggled across borders with fake passports. Scientists at the Fraunhofer IBMT have now developed a non-invasive, handheld smartphone-compatible scanner that uses ultrasound to determine whether a person has reached full legal age.
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Image: Surgeons during surgery; Copyright: UKR

Acute kidney injury: Early detection thanks to biomarker

08/11/2017

Major surgeries in the abdominal region often result in kidney injury in patients. Meanwhile, the clinical manifestations don't present until one or two days after the procedure. This causes physicians to lose valuable time to treat patients. The University Hospital Regensburg has researched a new concept for the treatment of kidney injuries for several years.
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Image: Three-dimensional image of a colored vessel structure; Copyright: René Hägerling

Pathology: detecting lymphedema with 3D microscopy

23/10/2017

According to the WHO, 300 million people throughout the world are affected by lymphedema. This condition occurs when fluid that flows between cells is no longer transported back into the blood circulation and accumulates in the skin. Triggers can be surgeries, injuries or genetic defects for example. A new microscopy technique could now also indicate the causes.
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Picture: two women perform exercises and are wired with electrodes; Copyright: University of Erlangen/Wolfgang Kemmler

Whole-body electromyostimulation training: fitness or prevention?

09/10/2017

Whole-body electromyostimulation (WB-EMS) promises time-efficient muscle strength training that has positive effects after just a few sessions per week. Its objective is a fast increase in muscle mass and reduction of body fat. Can WB-EMS training replace conventional strength and endurance training? And can it help to prevent diseases or pain?
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Image: Vials in a rack; Copyright: Messe Düsseldorf

MEDICA 2017: all about laboratory medicine at the MEDICA LABMED FORUM

02/10/2017

If you are interested in laboratory medicine and come to the MEDICA 2017, you will quickly notice that Exhibition Halls 1 and 2 were demolished. A new state-of-the art hall is meant to take their place. Until then, exhibitors from the field of laboratory medicine will be showcased at their temporary new location in the lightweight hall structures 3a and 18 on the fairgrounds.
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Image: Illustration of the Leipzig spoon, which is pushed to the back of the eye; Copyright: University of Leipzig/M. Francke

The "Leipzig Spoon" to cure pathological myopia

22/09/2017

Many people all over the world suffer from myopia, also known as nearsightedness. A severe elongation of the eyeball is the cause behind it. If it continues to progress, it ultimately leads to complete loss of vision. Now an innovative medical device intends to stop this progression in the future.
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Image: Collage of several MRI images of the heart, in which different locations are marked with red arrows; Copyright: University Hospital Münster/Ali Yilmaz

Myocarditis: more specific diagnosis thanks to molecular imaging

01/09/2017

There are many causes of myocarditis or inflammation of the heart muscle. Oftentimes, the culprits are viruses or bacteria and sometimes even an acute heart attack. Regardless of the cause, it creates a challenge for cardiologists: a diagnosis tends to be only nonspecific without a biopsy. A cardiac MRI and molecular imaging promise to provide assistance.
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Image: interferometric detection of scattered light, iSCAT; Copyright: MPL

Interface between Physics and Medicine: new interdisciplinary center

22/08/2017

Physics has always supported medical science, especially when it comes to practical implementation. Now physicists and health professionals join in collaborative research at an interdisciplinary Center in Erlangen and incorporate fundamental principles of theoretical physics in their studies of diseases.
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Image: A man is working at a laboratory bench, his screen is showing a program that recognizes his gestures; Copyright: Fraunhofer IPA/Heike Quosdorf

Laboratory automation: from note book to gesture recognition

08/08/2017

For centuries, scientific research has succeeded by chronicling experiments with pinpoint accuracy. Yet despite all the progress in the actual laboratory, recording is often still done manually, in notebooks, logs or computer systems for instance. In the future, a gesture recognition system could perform this task for scientists.
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Image: woman holding a sketch of a human lung; Copyright: panthermedia.net/Monkeybusiness

Molecular Microsystems: Preventing Exacerbations of Asthma and COPD

01/08/2017

An increasing percentage of the world population suffers from chronic inflammatory disorders of the respiratory system. Acute attacks often lead to a worsening of the disease and considerably reduce the patient’s lung volume. Nine institutes of a research alliance under the Leibniz Institute umbrella are working on technologies designed to predict and thus prevent exacerbations.
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Image: blood is taken from a finger and analysed by a blood testing device; Copyright:hes_so_valais_wallis

Without any delay: drug dose adjustment at the point of care

01/08/2017

Many therapeutic drugs are very powerful, but they are also very toxic at the same time. Thus, they have to be measured regularly, again and again, so that an adjustment of the individual drug dosage can be made. Until now, the "normal" way was to take the blood sample, send it to a central laboratory and get the results after some days. A new point-of-care test can measure it in 15 minutes.
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Image: Collage made of two images, one show a round, transparent plastic disc with micro channels, one shows a plastic chip; Copyright: Hahn-Schickard, Image Bernd Müller

Prenatal diagnosis: genetic analysis using droplet PCR

24/07/2017

A new analysis method that uses fetal DNA extracted from the mother’s blood is designed to non-invasively reach a prenatal diagnosis of genetic disorders in a child. A task force of the Hahn Schickard Society for Applied Research is an active part of the "ANGELab" project and co-developed this diagnostic procedure.
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Image: A large medical device with a treatment couch and four movable boxes; Copyright: panthermedia.net/Thomas Hecker

Cancer: refined treatment with proton minibeams

10/07/2017

Radiation therapies are an essential component of today’s oncology because they enable the treatment of localized tumors. Yet they have one major drawback: radiation damages not just tumor cells but also healthy tissue. One solution to solve this problem could be proton minibeam therapy, which uses finely focused beams.
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Image: A young woman takes another young woman's blood sample; Copyright: panthermedia.net/Arne Trautmann

Physician Assistant - profession with perspective

22/06/2017

The doctor's profession is exhausting and involves many different activities. For a long time, there have been discussions about how doctors can be supported by other specialists. One solution: help from so-called physician assistants.
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Image: A physician is holding a globe in his hands; Copyright: panthermedia.net/everythingposs

Modular Emergency Hospitals – Quick disaster response

08/06/2017

After earthquakes or other types of disasters, infrastructures are often damaged and local hospitals destroyed. A modular hospital, developed under the direction of the European Commission’s Humanitarian Aid and Civil Protection Department is designed to be ready for these types of disaster situations and support the emergency response.
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Image: In a movement laboratory, a man is wearing sensors on his legs and armst, while walking. During this he is being recorded and observed; Copyright: DAS BILD für ZHAW Gesundheit

"XoSoft" Project – Wearable Intelligent Exoskeleton

01/06/2017

After a stroke or as a result of aging, there are many situations when people are impaired in their walking ability and rely on a personal assistant or auxiliary aids and services. The XoSoft Project offers a solution: a soft exoskeleton that can be worn like a pair of leggings and stiffens or softens, depending on the situation.
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Image: Black-and-white picture, with some structures of the human body highlighted in color; Copyright: ARTORG Center for Biomedical Engineering Research, University of Bern

Cochlear implants: safe procedure thanks to surgical robots

22/05/2017

For many years, cochlear implants have restored a sense of hearing in people with certain types of hearing loss. For surgeons, the implantation requires a precise attention to detail under the microscope. The results for the patients improve significantly with a more precise placement of the electrode array. The use of a surgical robot can increase the accuracy of the procedure.
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Image: A hand tips on a lying tablet; Copyright: panthermedia.net / Koson Rattanaphan

Project A.L.I.N.A: Training in the interdisciplinary emergency room

08/05/2017

How can emergency room associates continue to educate themselves in a fast manner and without bureaucratic hurdles? The A.L.I.N.A Project, which gives associates new tools with special assistance services and learning environments, delivers the solution. We spoke with Prof. Sabine Blaschke at the University Hospital Göttingen about these tools and how they work.
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Image: Young Indian woman in yellow sari talking on mobile phone; Copyright: panthermedia.net / iphemant

Medical Technology for India – Market of the Future?

02/05/2017

India is a land of contradictions. On the one hand, it has densely populated cities with state of the art technology. On the other hand, two-thirds of the population still live under challenging hygienic and financial conditions in the rural areas. Despite these conditions or perhaps because of them, more and more medical technology companies from all over the world are interested in this market.
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Image: Compass pointing towards the word creativity. In the compass’s center is a ball that shows the Indian flag; Copyright: panthermedia.net/eabff

Technology: India offers potential for research and development

02/05/2017

When it comes to the production and development of tech products, many people immediately think of Germany, Japan, the U.S. or Taiwan. What’s often unknown is that an emerging market like India also offers great potential. After all, the country has a large number of experts and just as much technical knowledge at its disposal.
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Image: A women with a bald head and a headscarf, smiling, sitting on a sofa talking ot another woman; Copyright:Katharina Bia asiewic

Irreversible Electroporation – Last hope for liver cancer patients

24/04/2017

Liver cancer is the fifth most common malignant tumor in the world. The tumor can be removed through surgery or by utilizing thermal ablation techniques. If a treatment with conservative methods is no longer possible, there is an alternative: irreversible electroporation (IRE). The effectiveness of this method was now confirmed by a clinical study.
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Image: Computer-generated graphic showing two hip balls next to each other. Implantation of a sleeve is demonstrated on them; Copyright: revomotion GmbH Köln

Hip joint: sleeve versus endoprosthesis

10/04/2017

People with hip osteoarthritis often suffer from severe pain and only an endoprosthesis implantation can provide relief. This involves a major intervention and long-term rehabilitation because the implant requires the removal of a section of the thigh bone. The "MioHIP" research project looks for an elastic alternative.
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Image: Demonstrator; Copyright: Leibniz-IPHT

Medical imaging is onto septic fungi

03/04/2017

Instant treatment is absolute vital for patients developing sepsis. Providing a specific therapy early on is key. To manage this the pathogenic organisms need to be identified accurately. But a fungal sepsis can still be a hard nut to crack.
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Image: Graphic representation of Europe with small figures depicting the population; Copyright: panthermedia.net/Takahase Segundo

Hospital-acquired infections: pathogens know no borders

03/04/2017

Many aspects are uniformly regulated in Europe, however, hospital hygiene and MRSA prevention, for example, are not. The Netherlands plays a pioneering role in the fight against hospital-acquired infections. The country is an often-cited role model. But can other countries simply adopt the same system? And what makes it so different? MEDICA asked expert Prof. Alexander W. Friedrich.
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Image: A petri dish with yellow bacterial cultures on a black ground; Copyright: panthermedia.net/kwanchaichaiudom

Laboratory medicine: confronting infections with speed and foresight

03/04/2017

The laboratory is one of the most important and pivotal bastions in patient care. In the laboratory, acute, chronic and genetic diseases are diagnosed, the progression of diseases such as diabetes is regularly checked or specialists look for biomarkers to adapt cancer therapies.
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Image: Graphic of the generic architectur of the clinical data intelligence;  FAU Erlangen-Nürnberg Medizinische Fakultät

Medical Databases: One for All, All for One

01/03/2017

In the "KDI – Clinical Data Intelligence Project", researchers are trying to consolidate various types of data to make them useable and useful to both medical professionals and scientists. This is a tremendous undertaking, considering the data volumes from different sources. In this conversation with MEDICA, Dr. Martin Sedlmayr explains the project setup.
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Image: Surgeon is working at a simulator of the human back with two instruments; Copyright: HTWK Leipzig/Rebecca Schweier

RealSpine: realistic surgical simulation

22/02/2017

Surgeons need a great sense of touch. They first have to acquire this skill in simulation training before they can perform surgery on actual patients. Having said that, simulators are not just meant to teach the right movements; ideally, they should also provide a true-to-life experience of the surgical field – as is the case in RealSpine surgical training.
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Image: Detail of the app on a mobile phone; Copyright: Sonormed GmbH

Medical Device that fits in your pocket: music for Tinnitus relief

08/02/2017

Listening to your favorite music for at least 90 minutes a day and treating your tinnitus with it? Almost sounds too good to be true. Yet more and more German statutory health insurance providers pay for this treatment. We wanted to know more about it and spoke with Jörg Land, the CEO of Sonormed GmbH, about Tinnitracks.
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Image: Different eye stents lying beside a coin; Copyright: I.Chen

Stents versus Eye Drops: a new approach to aid glaucoma patients

01/02/2017

Using stents to treat glaucoma is not a new procedure but they have not been implanted into patients on a regular basis until only recently. But this is about to change, which is why MEDICA.de asked what these glaucoma mini-stents are able to do and who may be a good candidate for them. Professor Norbert Pfeiffer answered our questions.
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Image: Image of a bird in greyscale and blurred; Copyright: Universitätsklinikum Tübingen

Gene therapy for the treatment of achromatopsia

01/02/2017

Achromatopsia is a rare hereditary visual disorder. Along with total color blindness, patients most notably suffer from reduced visual acuity and increased sensitivity to light and glare.
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Image: Three physicians during a meeting; Copyright: KiTZ/Philipp Benjamin

Children's Tumor Center: consolidated treatment under one roof

02/01/2017

Treatments for children need to be different from treatment for adults – this also applies in oncology. Having said that, children do not just need new and different treatment concepts that still necessitate research. They also require the support from their families, who need to be nearby during treatment.
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Image: Graphic of an ebola virus against a blue background; Copyright: panthermedia.net/krishna creations

Who am I? Viruses on Nanosprings

21/12/2016

Within the scope of the VIRUSCAN project that is funded by the Horizon 2020 Research and Innovation Program of the European Union, Dr. Charlotte Uetrecht from Hamburg/Germany investigates individual viruses to be able to later identify them on a nanospring structure. MEDICA.de wanted to know: how does this work?
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Image: Zebrafish brain, fluorescence image (left) and 3D image (right); Copyright: private

"A 3D movie of the brain in action"

08/12/2016

Watching millions of neurons in the brain interacting with each other – for a long time this was possible only to a limited extent. The current techniques can visualize only superficial layers or the imaging they use is too slow. But now, Prof Daniel Razansky and his team have found a new method to visualize the brain activity – by using optoacoustics.
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Image: Eileen Stark prepares Dominik Wetzel for a measurement; Copyright: WHZ/Helge Gerischer

Paraplegia: moving muscles using electrical impulses

22/11/2016

It happens about 1,800 times per year: after a sporting or traffic-related accident, a person’s spinal cord is injured to where nerve tracts are severed and he/she becomes paralyzed. Researchers now want to develop software that measures the brain signals of paralyzed patients and sends out electrical impulses via a system to stimulate muscles, causing them to move again.
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Image: Hand of a person in the hospital bed, next to the call button; Copyright: panthermedia.net/bignai

Being safe: electronic call systems for hospitals

02/11/2016

Call systems: every hospital patient is familiar with them, but hardly anyone gives any thought to how they work. And yet they fulfill an important function because in an emergency, they "call" for help. Just think what might happen if they didn’t work. That is why they are subject to stringent safety regulations. We spoke with D.Eng. Matthias Rychetsky, who is familiar with call systems.
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Image: Graphic of a head within a computer network - many lines and bright colors; Copyright: panthermedia.net/Andrew Ostrovsky

My Avatar and Me – the digitization of healthcare records

04/10/2016

So far, avatars could only be found in computer games. But if researchers of the EU-wide www.myhealthavatar.eu project have their way, this could soon change.
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Image: Dark haired, smiling woman in a hospital; Copyright: UKR

Inflammatory bowel diseases: More patient comfort and autonomy thanks to an app

04/10/2016

Chronic inflammatory bowel diseases like Crohn’s disease and ulcerative colitis increasingly develop at a younger age and affect patients for life. Regular check-ups need to occur every two to three months. Now, a specially designed app intends to provide relief.
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Image: Open surgery at the forearm of a patient; Copyright: panthermedia.net/Chanawit Sitthisombat

Hemodialysis: Creating the AV fistula using catheters

08/09/2016

For many patients, the start of hemodialysis marks the lifelong dependency on needing their blood purified. But before they can actually begin treatments, a blood vessel in the patient's arm needs to be enlarged to where it can move enough blood and withstand being connected to the dialysis machine several times per week.
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Image: Hybrid OR; Copyright: Philips GmbH

Hybrid Operating Room: The OR of the Future Today?

01/09/2016

Patients take center stage during surgery. Their treatment should be as gentle and effective as possible, which is why there is a trend towards minimally invasive surgery (MIS). But minimal procedures require better supporting technologies. The hybrid operating room combines surgery and imaging systems and increasingly replaces conventional open surgery approaches with MIS.
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Image: girl in the MRI, physican besides; Copyright: Klinikum Dortmund/Dr. Lindel

MRI scan: Video projections help children overcome their fear

22/08/2016

A beautiful field of flowers, a trip to the beach or a visit to the zoo. Children can experience all of these at the Clinical Center Dortmund in a 270- degree projection on the wall. The Center created a space that is designed to help its little patients overcome their fear of MRI scans.
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Image: User interface of a software; Copyright: Helmholtz Zentrum München

Cell under observation: "The software lets us study the development on video"

08/08/2016

What happens when stem cells differentiate? What molecular characteristics do they have? Questions that can now be easier answered with the help of a new open-source software. We spoke with Prof. Fabian Theis at the Helmholtz Center Munich, who participated in the software development.
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Image: Closed eyes of a patient. Electrodes are attached above the eyebrows; Copyright: savir-center.com

Electrical Stimulation: Using Electrical Pulses to Combat Blindness

22/07/2016

Millions of people all over the world suffer from partial blindness – caused by glaucoma, a stroke or traumatic brain injury. For years, the loss of vision was deemed irreversible. But now a new treatment makes it possible to improve eyesight and vision.
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Graphic: Hand holds a smartphone, four pictures in the background with rescue situations

Emergency: app alerts first responders

08/06/2016

Just a few minutes can make the difference between life and death when a person loses consciousness or goes into sudden cardiac arrest. Unfortunately, emergency medical services cannot always be on location as fast as needed. To ensure immediate life-sustaining measures, the "mobile rescue" app was developed, which alerts emergency medical responders in the immediate vicinity of an emergency.
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Photo: Hospital  bed

Textiles used in hospitals and medical offices – germs don’t stand a chance

01/06/2016

Some hospitals have long banned the status symbol of physicians – the white coat. Research has shown that especially the sleeves were contaminated with various types of bacteria. But it’s not just lab coats that can spread germs in healthcare settings. This field uses a variety of different textiles. Wouldn’t it, therefore, make sense to apply antimicrobial finishes?
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Photo: Devices and products patients need to treat their diabetes; Copyright: panthermedia.net/ MihaPstock

Artificial pancreas: an (almost) automated diabetes treatment?

22/05/2016

The treatment for diabetes is very time-consuming for patients: they need to regularly monitor blood sugar levels, take medication and inject insulin. Poor self-management may result in a dangerous lapse in blood glucose levels. Yet external factors can also contribute to diabetes being out of control. An artificial pancreas system could offer relief.
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Photo: Three men pose during an award ceremony

Cardiac insufficiency: early diagnosis with ultrasound

02/05/2016

Heart failure or cardiac insufficiency presents an extra strain on patients because it severally limits everyday performance and deprives them of energy. Due to their intense need for movement, children are particularly strongly affected. However, the disease is frequently not detected until the physical performance is already declining. An early diagnosis could prevent this.
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Photo: ceramic joints

Knee at your fingertips

22/04/2016

How can you print ceramics, what purpose do they have and how benefits medical technology? Answers provides Dr. Tassilo Moritz from Fraunhofer Institute for Ceramic Technologies and Systems IKTS.
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Photo: Old woman with a smartphone

Health Apps: "Mobile Applications for smartphones have strengths and weaknesses"

22/03/2016

Medical apps like diabetes or high blood pressure diaries are becoming increasingly popular with smartphone users. There are many available choices out there but they are not always clear. Added to this is the question of how the data collected by the apps can be sensibly incorporated into treatment.
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Graphic: The pancreas and the surrounding organs

Pancreatic cancer: diagnosis via signature analysis

08/03/2016

Pancreatic cancer is one of the deadliest forms of cancer because it is difficult to diagnose and only presents with symptoms in the later stages. In the future, a laboratory test developed at the Greifswald University Medicine could make an early detection of this type of cancer and consequently a faster and better treatment possible.
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Photo: Researcher is looking at a microfluidic LabDisc

Point-of-care-testing: from disc to diagnosis

22/02/2016

Easy solutions that deliver results quickly are a great asset in medicine: patients receive their diagnosis faster and physicians have more time to treat them. Such tools also work without sophisticated resources and trained personal. A device currently developed in a project funded by the European Commission could bring all of this to point-of-care-testing for infectious diseases.
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Photo: two physicians working at a test set-up

Atherosclerosis: Getting to the root of the problem with a turbo gene

09/02/2016

Many people suffer from atherosclerosis, especially in developed countries. The buildup of fatty deposits inside the arterial blood vessels leads to strokes and heart attacks. Now, a new method is designed to get to the root of the problem, and with the help of nanoparticles inject new turbo replacement cells into the blood vessels which are intended to exert their curative effect.
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Photo: Knee implant

Customized Implants cover bones optimally

22/01/2016

It may fits, but somewhere it still tweaks. Although a suit off the rack serves its purpose, it is still far from being an ideal solution. With a custom made heart it is different. It is similar with implants. Often patients complain about the fact that those implants feel strange. 3D printing is on the best way to change this. Here, the implants are adapted to the carrier.
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Photo: artificial heart valve

Artificial heart valve: "The structure is meant to be broken down again by the body at a later point."

08/01/2016

There are various artificial heart valves available for children, but they have one essential drawback: they need to be replaced because the children are still growing. The artificial valve, on the other hand, remains the same size – and subsequently becomes too small. This is why an artificial heart valve that grows over time would be ideal.
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Photo: Pregnancy test

Disaster medicine or disastrous medicine?

04/01/2016

Most Europeans think it was a long time ago, but the residents of West Africa clearly feel the consequences of the Ebola epidemic that broke out in December 2013 and still continues today. So far, approximately 11,300 people have died as a result of the outbreak; more than 28,000 contracted the disease.
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Photo: Magnet draws zigzag lines

Magnetogenetics: how neural stem cells grow in a certain direction

01/12/2015

If you could stimulate brain cells to grow in a specific direction, you would probably be able to achieve a significant improvement in the health of patients suffering from Parkinson’s disease. This is why the MAGNEURON project focuses on this approach. The EU is funding the project with approximately 3.5 million Euros.
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Photo: Surgeon uses command devices for a robot

Robotics: surgery with feeling

02/11/2015

Minimally invasive surgeries are gentler on the patient but have one distinct disadvantage for the surgeon: he is not able to interact directly with the operating field. Sometimes he misses impressions that are very important to the success of the intervention. The MiroSurge robot for surgical applications which transmits feedback to the surgeon can help.
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From the periodic table of elements into medicine: silicon for theranostics

01/10/2015

Semiconductor nanoparticles for biomedical applications have been researched for some time now. Not only are they millionths of a millimeter in size, they also offer great potential for cancer diagnostics and therapy, so-called theranostics. They enter cells, are activated by ultrasonic radiation and destroy the cells using the generated vibration.
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Theranostics: Complex particles for tomorrow's medicine

01/10/2015

It is a portmanteau, a mixture of two words. This way it saves us time and trouble while speaking because the human speech apparatus is lazy. And it describes a mixture of procedures: the combination of two procedures that would normally be separate in medicine. We are talking about theranostics.
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Small companions: How wearables change our lives

01/09/2015

They can be seen everywhere: at the wrists, in the ear, clipped to the belt. Wearables are small technical assistants who are built to collect and partially also to analyze data. Some of them collect measurable health data, others "only" count their user’s steps or measure the surrounding UV radiation. The fact is, however, that wearables are en vogue and are used for many different cases.
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Radiopharmaceuticals: Individualized diagnostics and therapy

03/08/2015

Malignant tumors can be fought with X-rays – usually with radiation therapy from outside the body. Nuclear medicine physicians can also accomplish this inside the body with radioactive materials, called radiopharmaceuticals. They also offer big benefits for clinical diagnostics as long as a specific target can be assigned to them.
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ECG measurements: "Our chest strap moistens itself"

01/07/2015

When measuring myocardial activity, it is important for the skin to always stay moist under the electrodes of the ECG. Only then can data be consistently transferred. Athletes have an easier time with this: they are used to sweating. This is a lot harder for older patients.
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Tumor markers: State-of-the-art diagnostics for personalized medicine

01/06/2015

When cancer is diagnosed, the terms tumor markers or biomarkers keep popping up. They describe characteristics that are not found in healthy persons. The classic tumor markers can be easily detected in blood samples or other body fluids. Other analysis methods require more effort. Yet they all share one thing in common: biomarkers indicate a potential tumor.
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Cancer Immunotherapy: Individual mutations as new target structures

01/06/2015

A tumor is as unique as the person who is affected by it. For a long time, it was assumed this would make treatment more difficult since cancer drugs are not able to be one hundred percent effective in targeting the affected cells. In this interview with MEDICA.de, Professor Ugur Sahin explains why it is precisely these individual mutations that make him hopeful for a new type of therapy.
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Statutory Skin Cancer Screening: "This is not just about mortality rates"

04/05/2015

Since the end of April 2015, the long-awaited evaluation report on the skin cancer screening programs offered by German health insurance providers is now finally available. We spoke with Dr. Ralph von Kiedrowski, Board Member of the German Dermatologist Association (German: Berufsverband Deutscher Dermatologen) on what the screening can accomplish and his take on the G-BA report.
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Crisis Management: Keeping the big picture in mind

02/03/2015

How should a hospital best respond to an emergency and which types of crises should it be prepared for? We spoke with Professor Ronald Glasberg at the SRH Hochschule Berlin on this subject.
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Photo: Object slides

Tissue storage: "Our top biobanks are internationally leading the charge"

02/02/2015

Only projects with a solid foundation are successful in the long run. This is also true for science. Biobanks are the most important component of this foundation when it comes to fundamental biomedical research: Only high quality tissue samples that are stored there make conclusive research possible - for example in search of the causes of tumorigenesis.
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Photo: interaction between the proteins

IBD: When genetics and environment interact

05/01/2015

T-cells are the guardians of our immune system. When they show changes, it can lead to severe inflammatory responses in the body. It is believed that the T-cells in persons who are affected by inflammatory bowel disease don’t work properly. Two proteins that can be found on activated T-cells and that interact with each other are now being analyzed.
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Making Your Own End-of-Life Decisions: “All options of palliative care, pain management and continued life need to have been explained to the patient“

01/12/2014

How does a physician handle a patient, who wants to die and what rights do I actually have as a patient? Legal practitioners do not automatically answer these and other questions. We talked about this subject with MD-PhD Ralf Jox from the Institute of Ethics, History and Theory of Medicine at the Ludwig Maximilians University of Munich, Germany.
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Xenon magnetic resonance imaging: making pathological changes in the body visible

03/11/2014

As an imaging procedure, magnetic resonance tomography has become essential in clinical practice, since it can easily make organs and tissue visible. However, until now abnormal cancer cells or small centers of inflammation remained almost invisible. Now cell biologists from Berlin, Germany, have succeeded in fixing this problem with xenon magnetic resonance imaging.
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Wound treatment with fish skin

03/11/2014

The treatment of chronic wounds is extremely problematic. Chronic wounds can take months or years to heal and some even never heal resulting in over 100.000 amputations taking place annually in the US alone. A new technology from Iceland, that is based on fish skin and is already used clinically, allows for improved healing of chronic and burn wounds.
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Photo: Dr. Anna-Maria Liphardt

Laboratory in Space: Hot on the Trails of Cartilage Degradation

01/10/2014

On November 10, 2014, astronaut Alexander Gerst will return to Earth from the International Space Station (ISS). He is not just anxiously expected by his family, but also by Dr. Anna-Maria Liphardt from the Institute of Biomechanics and Orthopedics at the German Sport University Cologne
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Persistent vegetative state: brain stimulation with laser beams

01/09/2014

The public only notices diseases when celebrities become patients: in the spring of 2014, Formula One driver Michael Schumacher fell into a coma for several months as the result of a head injury caused by a skiing accident. These types of accidents show how delicate the brain responds to injuries. Brain stimulation could possibly support the rehabilitation of vegetative patients.
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Pediatric anesthesia: "I would object to a specialty medical training"

01/09/2014

When very young children already need to be in the operating room, it’s not just the parents that are concerned. This type of situation is a special challenge for the entire operating team, because children are always very special patients - especially since they are not just simply small grown-ups!
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Diagnosing Parkinson's: the skin is revealing

01/07/2014

In patients with Parkinson's, neural cells in the brain die off that produce the neurotransmitter dopamine. Certain physical symptoms that can indicate the disease follow years later. But a reliable diagnosis can only be made through examination of the brain after the patient's death, and not during his lifetime.
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Fat is the best medicine: "Adipose tissue contains many multipotent stem cells, approximately 500 times more than bone marrow"

01/07/2014

The not so popular “love handles“ could revolutionize medicine in the near future. In cooperation with the University of Rostock (Professor Hermann Seitz), the human med AG Company currently seeks to develop a device that is able to gently remove adipose tissue during surgery and subsequently isolate stem cells.
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Sports and cancer: no panacea, but a necessary aid

02/06/2014

When are sports healthy, how often should you engage in sports and what effect do sports have on the body – over the past few decades, there were always different answers to these questions. Many studies that were conducted in the past however confirm the assumption that sports and exercise always support health, even if someone is already sick.
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Mobile assistance systems: "The device automatically notifies if something is not right"

02/05/2014

Staying active and mobile when you are old – who doesn’t want that? People suffering from dementia can often only dream about that. The fear of not finding your way back home or not getting any help in an emergency severally restricts many affected people in the way they live their lives. Yet there are many people, who could still independently participate in life despite mild dementia.
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Seminars for physicians: "Physicians are obligated to continue their education for the safety of their patients"

04/03/2014

Continuing education is an integral part of the medical profession, because research continuously delivers new findings that sooner or later make their way into patient treatments. How does an event need to be organized to provide the highest level of benefit for the participants? MEDICA.de spoke with Eva Ningel, Managing Director for beta seminare bonn berlin GmbH (bsbb).
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Radiology and technology: "Numerous phantom studies have been conducted that prove the advantages of this new CT system"

03/02/2014

Radiologists usually do their work after oncologists when it comes to cancer treatment. Yet modern radiology also provides treatments at this point. MEDICA.de spoke with Professor Stefan Schönberg, Director of the Institute of Clinical Radiology and Nuclear Medicine at the University Medical Center Mannheim, Germany, about the use of a new computer tomograph and its benefits for patients.
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Study approach: surgical trials mean more safety in the operating room

06/01/2014

Whether a surgical suture is better applied manually or with a surgical stapler can be determined through trial and error. Determining which method guarantees patient safety best should also not just be based on a surgeon’s experience. Controlled studies are the method of choice to assess both well-proven and new techniques in the operating room.
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Clinical trials: "Registry-embedded clinical trials are the way of the future"

06/01/2014

Even medical risk products are not always tested as thoroughly as would be necessary – be it because of criminal energy, lack of know-how or financial reasons. A revision of clinical trial procedures could not only fix loop holes and methodological flaws. Products and methods could also be brought into general medical care more quickly under new rules.
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