16/03/2018The accumulation of mutations in the human genome is at the origin of cancers, as well as the development of resistance to treatments. The Cyclin E and Myc genes are active in the control of cell division. When they are mutated, for example in response to a carcinogen, these genes induce cells to start replicating their DNA prematurely during the cell cycle.
16/03/2018Metabolic changes in cells can occur at the earliest stages of disease. In most cases, knowledge of those signals is limited, since we usually detect disease only after it has done significant damage.
15/03/2018Working with cells grown in the lab, Johns Hopkins researchers have identified a biochemical pathway that allows a structure within cells, called the Golgi apparatus, to combat stress caused by free radicals and oxidants. The research team showed that this pathway can be activated by a drug called monensin, which is commonly used as an antibiotic in animal feed.
15/03/2018A newly-discovered hereditary mutation is responsible for an increased production of erythropoietin (EPO) in the blood. This mutation causes a messenger RNA (mRNA) that is not normally involved in the formation of proteins to be reprogrammed so that it produces EPO, thus abnormally increasing the number of red blood cells.
14/03/2018Cardiovascular disease patients have lower levels of an important family of protective molecules in their blood in the morning, which could be increasing their risk of blood clots and heart attacks at those times, according to early research led by Queen Mary University of London.
14/03/2018Brown adipose tissue has played a key role in prevention research since its presence was first documented in adults. However, there was no non-invasive method of measuring its heat generation. A team at the Technical University Munich (TUM) and the Helmholtz Zentrum München has now succeeded in making the activity of brown adipose tissue visible without injecting substances.
13/03/2018A clinical study coordinated by the French National Research Institute for Sustainable Development and Chiang Mai University with their Thai, American, and French partners, strengthens the case for a new strategy to prevent mother-to-child transmission of the hepatitis B virus.
13/03/2018A discovery led by scientists at the University of Alberta and McGill University is providing hope of a new therapeutic target in Multiple Sclerosis (MS) patients, which could one day be used to prevent the symptoms and progression of the disease.
12/03/2018About 1 in 2,500 people have a degenerative nerve disease called Charcot-Marie-Tooth (CMT). The disease is typically diagnosed in children, who can lose their ability to walk and use their hands for fine motor skills. There is no cure – yet.
12/03/2018Scientists on the Norwich Research Park have discovered a key mechanism by which gut bacteria colonise and adhere to their specific hosts. The finding may lead to new, improved probiotics with optimised abilities to colonise our gut and battle infections by forming strong associations with the host as biofilms.
09/03/2018Scientists identify a natural brake on the allergic attack.
09/03/2018Victims are not necessarily on a path towards poor health in adulthood.
08/03/2018There are currently an estimated 1.8 million people in Germany who have atrial fibrillation but do not know it. Now a Dutch company has developed an app with which a smartphone can be used to detect this dangerous cardiac arrhythmia. Scientists at the TU Darmstadt are helping to ensure the recorded data is interpreted correctly and efficiently.
08/03/2018Researchers at the Emory Rollins School of Public Health and U.S. Centers for Disease Control and Prevention have found that high proportions of patients with prediabetes are at substantial risk for cardiovascular disease and chronic kidney disease. Their findings are published in "The Lancet Diabetes & Endocrinology".
08/03/2018Automation makes work life easier in many ways but is it also a solution for analyzing medical images? Is a computer actually reliable enough to assist in the medical decision making process? Researchers in Landshut examine how machine learning algorithms can work more reliably and support radiologists.
07/03/2018A research describes the anti-cancer effects of a natural alkaloid extracted from Daffodils. Led by Denis Lafontaine, affiliated with the Faculty of Sciences at the ULB, the researchers have discovered that this compound triggers the activation of an anti-tumoral surveillance pathway.
07/03/2018The study shows that blockade of the protease MT4-MMP increases the activity of blood-patrolling monocytes in the circulation.
06/03/2018By examining the cornea of the eye with a special microscope it may be possible within ten minutes to diagnose if a person with type 2 diabetes has nerve damage. This according to a study among diabetics in Skellefteå, north Sweden.
06/03/2018Physicists have devised a new method of investigating brain function, opening a new frontier in the diagnoses of neurodegenerative and ageing related diseases.
05/03/2018For seven years as a graduate student at Montana State University, Rebecca Hochstein hiked into the backcountry of Yellowstone National Park.
05/03/2018Prenatal exposure to male hormones influences which activities girls are interested and engage in, but the effects of those hormones don't extend to gender identity or who they socialize with, according to Penn State researchers.
02/03/2018A bone marrow transplant is often the only therapy available to save leukaemia patients, but the risk of complications is high. In spite of devoting considerable time and effort to finding a suitable donor, nearly half of all patients experience an unwanted reaction of their immune system, which often attacks their skin and liver and in up to 50% of cases the intestines.
02/03/2018UZH researchers have discovered a previously unknown way in which proteins interact with one another and cells organize themselves. This new mechanism involves two fully unstructured proteins forming an ultra-high-affinity complex due to their opposite net charge. Proteins usually bind one another as a result of perfectly matching shapes in their three-dimensional structures.
01/03/2018Academy Professor Riitta Lahesmaa’s research group from Turku Centre for Biotechnology of the University of Turku and Åbo Akademi University, Finland, has discovered a new regulator of the immune system, a key factor that controls development of regulatory T cells.
01/03/2018People suffering from major depressive disorder, MDD, have reduced arginine levels, a new study from the University of Eastern Finland shows. Arginine is an amino acid which the body uses to produce, e.g., nitric oxide. Nitric oxide, in turn, is a nervous system and immune defence mediator, and it also plays a role in vascular regulation.
01/03/2018Conventional cancer treatment selection typically depends on the location of the tumor. However, this approach ignores the distinct gene mutations in the tumor of the individual patient. New cancer research approaches increasingly emphasize the concept of personalized therapy.
01/03/2018Personalized medicine does not follow a "one-size-fits-all" treatment approach but emphasizes a "tailor-made" paradigm, meaning a treatment is customized to each individual person's case. For patients, this increases the chances of treatment success and means fewer side effects. While the approach originates in the field of oncology, it is now also increasingly applied to other disease patterns.
01/03/2018Everyone is different. This statement also applies to our health. Cancer, in particular, can look and progress differently depending on the individual person. That’s why every patient ideally also needs a customized treatment that is tailored to their individual needs. But how feasible is this idea?
28/02/2018The bacterium Streptomyces chartreusis is an antibiotic-producing bacterium that releases more metabolites into the surrounding medium than scientists assumed based on the analysis of the genome. Many of the substances are likely released to mediate interactions with its environment. They might also include molecules that are of interest as potential pharmaceutical agents.
27/02/2018The Women's Health Initiative found that hormone therapy (HT) use was associated with a reduction in vertebral fracture risk. A new study shows these same benefits may also guard against a woman's risk of developing hyperkyphosis, an exaggerated curvature of the spine that creates a forward stooped posture.
27/02/2018Key repeating moments in the film give viewers the information they need to understand the storyline. The scenes cause identical reactions in the viewer's brain. The results deepen our understanding of how the brain functions, how narratives work in film, and memory mechanisms impaired by conditions such as Alzheimer's disease.
26/02/2018Constrictions of the coronary blood vessels is a possible consequence of type 1 diabetes, and one that can eventually lead to myocardial infarction or heart failure. Generally speaking, women are afflicted by coronary artery disease later than men, but if a woman has type 2 diabetes, the advantage is negated.
26/02/2018Bacteria-killing viruses could be employed not just in health care, but also in the food industry, a study conducted at the University of Helsinki indicates. The researchers have been investigating the possibility of utilising phages in eradicating foodborne pathogens and preventing food poisoning.
23/02/2018Scientists at The Scripps Research Institute (TSRI) have achieved a major milestone toward designing a safe and effective vaccine to both treat heroin addiction and block lethal overdose of the drug. Their research, published today in the journal Molecular Pharmaceutics, shows how a new anti-heroin formulation that is safe in animal models remains stable at room temperature for at least 30 days.
23/02/2018Each year, influenza kills half a million people globally with the elderly and very young most often the victims. In fact, the Centers for Disease Control and Prevention reported 37 children have died in the United States during the current flu season.
22/02/2018Here on Earth, all experiments are bound by gravitation. Yet, freed from gravity's grip, tumor cells, for example, behave in an entirely different way. As part of the "Thyroid Cancer Cells in Space" project by the University of Magdeburg, smartphone-sized containers carrying poorly differentiated thyroid cancer cells are sent into space.
22/02/2018International team of scientists led by Roderic Guigó at the Centre for Genomic Regulation in Barcelona showed that changes in gene expression in different tissues triggered by death can be used to predict the time of death of an individual.
22/02/2018Fluctuations in female sex hormones could play a role in the development of allergies and asthma, a major review of evidence suggests.
21/02/2018More than 30 million Americans suffer from osteoarthritis making it one of the most common age-related diseases.
20/02/2018The brain mechanisms of basic emotions such as anger and happiness are fairly similar across people. Differences are greater in social emotions, such as gratitude and contempt.
20/02/2018The field of biomimetics offers an innovative approach to solving human problems by imitating strategies found in nature. Medical research could also benefit from biomimetics, as a group of international experts from various fields, including a wildlife veterinarian and wildlife ecologists from Vetmeduni Vienna, point out using the example of chronic kidney disease.
19/02/2018Amyloid beta pathology - protein deposits in the brain - might have been transmitted by contaminated neurosurgical instruments, suggests a new UCL-led study.
19/02/2018In a recent study, a research group at MedUni Vienna has published further details about the function of an enigmatic protein. The biological necessity of this protein, which can chemically alter certain building blocks of the genetic information, has been debated for quite a while.
16/02/2018Scientists from the University of Zurich have succeeded for the first time in tracking individual stem cells and their neuronal progeny over months within the intact adult brain. This study sheds light on how new neurons are produced throughout life.
16/02/2018Symptoms of alcoholism make it more difficult for some people to regularly take the prescription drug naltrexone, which could help treat their disease, a researcher at Oregon State University has found.
15/02/2018About 15 million Americans don't have a typical nine-to-five workday, and many of these - nurses, firefighters and flight attendants, among many other professions - may see their schedule change drastically one week to the next.
15/02/2018Every kind of cancer can spread to the spine, yet two physician-scientists who treat these patients describe a paucity of guidance for effectively providing care and minimizing pain. To resolve the confusion and address the continually changing landscape of spine oncology, a recent Michigan Medicine-led publication details a guide to explain the management of spinal metastases.
14/02/2018A diet rich in saturated fat and sugar not only leads to obesity, it creates inflammation in the nucleus accumbens, a part of the brain that controls mood and the feeling of reward. And this inflammation can lead to depressive, anxious and compulsive behaviour and disrupt metabolism, according to a new study by researchers at the University of Montreal Hospital Research Centre (CRCHUM).
14/02/2018Scientists at the University of Delaware and the University of Illinois at Chicago have found a new way to kill liver cancer cells and inhibit tumor growth. First, they silence a key cellular enzyme, and then they add a powerful drug. They describe their methods in a new paper published in Nature Communications.
13/02/2018The internal anatomy of our lungs is surprisingly variable, and some of those variations are associated with a greater risk of chronic obstructive pulmonary disease (COPD), a new study led by researchers at McGill University and the Columbia University Irving Medical Center has found.
13/02/2018As the fight against drug-resistant infections continues, University of Leeds scientists are looking back at previously discarded chemical compounds, to see if any could be developed for new antibiotics.
12/02/2018Aortic aneurysm – the dilation of the aorta – is a serious condition that lacks effective drug treatment. Researchers at Karolinska Institutet in Sweden report in the journal PNAS, however, that a common asthma drug can retard the development of aortic aneurysm in mice.
12/02/2018Infants can sometimes develop an allergy to cow's milk that usually subsides by adulthood but may increase the risk for developing other allergic diseases.
09/02/2018Researchers at the Institute of Industrial Science (IIS), the University of Tokyo, CNRS and INSERM, report a new organ-on-a-chip technology for the study of blood vessel formation and drugs targeting this event.
09/02/2018Researchers have identified a key process that enables the Ebola virus to infect host cells, providing a novel target for developing antiviral drugs.
08/02/2018Super-resolution microscopy reveals fine detail of cellular mesh underlying cell membrane.
08/02/2018Indiana University researchers have made an important step forward in the design of drugs that fight the hepatitis B virus, which can cause liver failure and liver cancer.
07/02/2018Human papilloma virus (HPV), the culprit behind cervical cancer and some forms of head and neck cancer may hide in small pockets on the surface of tonsils in people not known to carry the virus.
07/02/2018Scientists from the University of Zurich have redesigned an adenovirus for use in cancer therapy. To achieve this they developed a new protein shield that hides the virus and protects it from being eliminated. Adapters on the surface of the virus enable the reconstructed virus to specifically infect tumor cells.
06/02/2018A new study conducted by Ohio University scientists suggests that a little more sunlight might help restore damage to your cardiovascular system.
06/02/2018In the biennial mammography screening programme, the most frequent diagnosis of breast cancer in its preliminary stages is, biologically, the most aggressive form. High-grade ductal carcinoma in situ holds the greatest risk of developing into a so-called invasive carcinoma.
05/02/2018CHOP researchers find outcomes are similar, but broader-spectrum antibiotics have higher risk of adverse effects.
05/02/2018Screening for mutations influencing the migration of nerve cells in mice, scientists found a gene that plays a role in the transport of proteins within nerve cells. If less of the protein is present in the developing mouse, the scientists found that its brain showed severe defects.
02/02/2018In both cell cultures and mouse models, a drug used to treat Hepatitis C effectively protected and rescued neural cells infected by the Zika virus - and blocked transmission of the virus to mouse fetuses.
02/02/2018Diabetes patients have an increased risk of suffering serious infections or death compared to the general public, new research has shown. The study analysed the electronic GP and hospital records of more than 100,000 English adults aged 40 to 89 years with a diabetes diagnosis, and compared them to those without a diabetes diagnosis.
01/02/2018A study led by researchers at Keele University has found the risk of death in later life due to coronary heart disease doubles in women who give birth prematurely.
01/02/2018A person needs immune-suppressive drugs for organ transplants but not typically for transplants in the eye. How come? Like a few other parts of the body, some components of the eye, like the lens, don't have direct access to vessels that deliver immune cells. They were assumed to be places that immune cells couldn't go. They were immune privileged.
31/01/2018Screening a class of recently-developed drug compounds, so-called CDK inhibitors capable of blocking CDK7/12/13 proteins, against hundreds of different human cancer cell lines, researchers at Dana-Farber/Boston Children's Cancer and Blood Disorders Center have found that CDK12 inhibitors pack a particularly lethal punch to Ewing sarcoma, a rare cancer typically affecting children and young adults.
31/01/2018In a new study, published in Cell Reports, researchers from the William Harvey Research Institute at Queen Mary University of London used cells derived from urine to take the first step in generating an artificial adrenal gland.
30/01/2018The benefits of low-intensity physical activity, such as standing, walking or doing household chores, can be more health beneficial than once thought. According to a study from Karolinska Institutet published in the journal Clinical Epidemiology, replacing half an hour's sedentariness a day with everyday activity reduces the risk of fatal cardiovascular disease by 24 percent.
30/01/2018Achievement in the field of cancer research: Biologists and chemists at the University of Konstanz decipher a molecular mechanism of the cell with relevance for the development of cancer and the fight against that disease. Particularly important is the interaction between the tumour-suppressor protein p53, known as the guardian of the genome, and the enzyme PARP-1, the caretaker of the genome.
29/01/2018Researchers at the Université libre de Bruxelles and University of Cambridge identified the role of key gene Mesp1 in the earliest step of cardiovascular lineage segregation. This discovery may help to better understand congenital heart defects.
29/01/2018Nerve cells in the skin help wounds to heal. When an injury occurs, cells known as glial cells change into repair cells and disseminate into the wound, where they help the skin to regenerate, researchers from the University of Zurich have shown.
26/01/2018Researchers have developed a universal vaccine to combat influenza A viruses that produces long-lasting immunity in mice and protects them against the limitations of seasonal flu vaccines, according to a study led by Georgia State University.
26/01/2018Enhanced lifestyle counselling prevents cognitive decline even in people who are carriers of the APOE4 gene, a common risk factor of Alzheimer's disease, according to a new study published in JAMA Neurology.
25/01/2018Researchers have long wondered how our cells navigate inside the body. Two new studies, in which Lund University researcher Pontus Nordenfelt has participated, have now demonstrated that the cells use molecular force from within to steer themselves in a certain direction. This knowledge may be of great significance in the development of new drugs.
25/01/2018An international research team has conducted successful phase II clinical tests of a new anti-malaria medication. The treatment led to a cure in 83 cases. The new combination of drugs was developed by Professor Peter Kremsner of the Tübingen Institute of Tropical Medicine and the company DMG Deutschen Malaria GmbH.
24/01/2018Down's syndrome – also known as trisomy 21 – is a genetic disorder caused by an additional third chromosome 21. Although this genetic abnormality is found in one out of 700 births, only 20% of foetuses with trisomy 21 reach full term. But how do they manage to survive the first trimester of pregnancy despite this heavy handicap?
24/01/2018Data collected during a long-term health study provides additional evidence for a link between increased risk of cancer in individuals with advanced gum disease.
23/01/2018For the first time, researchers have described atom-by-atom changes in a family of proteins linked to amyotrophic lateral sclerosis (ALS), a group of brain disorders known as frontotemporal dementia and degenerative diseases of muscle and bone. Their findings appear in the journal "Molecular Cell".
22/01/2018Research does not always occur in laboratory settings. As part of citizen science, citizens collect data and make it available for research projects. Now, this approach is also adopted in medicine by way of patient science: in a new project, patients take part in cystic fibrosis research. The goal is to improve the lives of those who are affected by this chronic disease.
19/01/2018Osaka University study identifies antibody that alleviates symptoms in neuromyelitis optica in rats.
19/01/2018Around 400 million people world-wide suffer in some form or other from a grass pollen allergy (rhinitis) – with the usual symptoms such as a runny nose, cough and severe breathing problems.
18/01/2018An analysis of several hundred DIPG and related tumors, including Chad Carr's, finds an overlooked key factor in determining prognosis for the aggressive childhood brain cancer.
18/01/2018A paper just published in "Nature Biotechnology" outlines a pioneering method of screening a person's diverse set of antibodies for rapid therapeutic discovery. Antibody proteins are an important part of the human immune system that specifically target foreign viruses and bacteria, and they have been the fastest-growing class of approved drugs in the past several decades.
17/01/2018A team of scientists led by Darío Acuña-Castroviejo, professor at the University of Granada (UGR), has published the results of a new breakthrough in molecular mechanisms of the anti-parkinsonian activity of melatonin.
15/01/2018A groundbreaking report, led by Professor Mark Lawler, Chair in Translational Cancer Genomics at Queen’s University Belfast highlights a plan to end bowel cancer, the second most common cause of cancer death in Europe.
15/01/2018COPD patients suffer from chronic inflammation of the respiratory tract. Certain enzymes, so-called protein kinases, regulate the inflammation process. They are indirectly over-activated due to smoking, due to pro-inflammatory factors characteristic of COPD, and due to respiratory infections.
12/01/2018Virus hides in plain sight by being less aggressive.
12/01/2018Psychologists reveal neural underpinnings of trypophobia.
11/01/2018Researchers have identified several new genes responsible for Alzheimer's disease (AD) including those leading to functional and structural changes in the brain and elevated levels of AD proteins in cerebrospinal fluid (CSF).
11/01/2018An old drug supercharged by University of Queensland researchers has emerged as a new antibiotic that could destroy some of the world's most dangerous superbugs.
10/01/2018A new method to test the likelihood of a drug turning into a potentially harmful version of itself when it enters the body has been developed by researchers at Cardiff University.
10/01/2018Newly described stretches of super-silenced DNA reveal a fresh approach to reprogram cell identity to use in regenerative medicine studies and one day in the clinic, according to a study in Molecular Cell last week by investigators from the Perelman School of Medicine at the University of Pennsylvania.
09/01/2018Bielefeld biochemists confirm cause of initially unclear symptoms.
08/01/2018Over the past couple of years, scientists at the University of Eastern Finland have shown that sauna bathing is associated with a variety of health benefits.
08/01/2018Researchers at Indiana University School of Medicine have successfully developed a method to grow hairy skin from mouse pluripotent stem cells-a discovery that could lead to new approaches to model disease and new therapies for the treatment of skin disorders and cancers.
08/01/2018Few patients with heart failure are fortunate enough to receive a donor's heart. Ventricular assist devices (or heart pumps) have been around for several years and are designed to buy time as patients wait for a transplant. Unfortunately, the body doesn't always tolerate these devices.
05/01/2018Scientists at Helmholtz Zentrum München have discovered a mechanism that amplifies the autoimmune reaction in an early stage of pancreatic islet autoimmunity prior to the progression to clinical type 1 diabetes. If the researchers blocked the corresponding molecules, the immune system was significantly less active.
05/01/2018A group of researchers at Osaka University developed a synthetic tissue using synovium-derived mesenchymal stem cells (MSCs) for treating damaged cartilage, which had previously been incurable and had no effective therapies.
04/01/2018Researchers from Centre for Plant Biotechnology and Genomics (CBGP), a joint research centre of UPM and INIA, ha found that certain compounds carried by allergic proteins would be collaborating agents needed in the processes that trigger immune responses with the appearance of allergic symptoms.
04/01/2018While it is commonplace for operating room staff to work together as a team, the collaboration of operating room systems does not always work so well – many devices are still separated from one another, causing the OR processes to be prone to mistakes. The same applies to surgical navigation technologies that represent the interface between imaging, the surgeon and therapeutic devices.
04/01/2018Hokkaido University researchers have uncovered a cellular protein that stabilizes a tumor promoting signaling pathway, suggesting a new target to treat prostate cancer.
22/12/2017The antidepressant clomipramine may also alleviate symptoms of multiple sclerosis (MS), specifically in its progressive form, i.e. when it occurs without relapses or remissions. As yet, drugs for this type of MS have been virtually non-existent.
22/12/2017Scientists at IST Austria and in Paris develop framework connecting and extending previous theories on how neurons in our sensory systems select and transmit information.
21/12/2017By attaching specialised molecules to the backbone of DNA, researchers have made it easier to detect rare molecules associated with early disease.
21/12/2017Dementia affects millions of people worldwide, robbing them of their ability to think, remember and live as they once did. In the search for new ways to fight cognitive decline, scientists report in ACS' Journal of Agricultural and Food Chemistry that blueberry vinegar might offer some help.
20/12/2017A new study suggests that noise sensitivity can be seen in the grey matter volume of brain structures linked to emotional and interoceptive processing.
20/12/2017Sixty percent of newborns are affected by jaundice during their first days of life. In most cases, the condition is harmless. The ailment is more pronounced in premature babies, whose treatment involves irradiation with blue light in a special incubator – naked and alone.
19/12/2017A "cure" for haemophilia is one step closer, following results of a groundbreaking gene therapy trial led by the NHS in London.
19/12/2017A new study led by scientists at the University of Southampton has found that inherited variation in a particular gene may be to blame for the lower survival rate of patients diagnosed with early-onset breast cancer.
18/12/2017An antibiotic candidate compound shelved in the 1970s in favour of more worthwhile drugs could be worth a second look, new research has found.
18/12/2017Scientists of the Friedrich Schiller University Jena, Germany succeeded in developing an efficient method to treat Mucoviscidosis. Crucial are nanoparticles that transport the antibiotics more efficiently to their destination.
22/11/2017Human trafficking is a global crime that often preys on underage persons and forces them into prostitution and forced labor. In most cases, people are smuggled across borders with fake passports. Scientists at the Fraunhofer IBMT have now developed a non-invasive, handheld smartphone-compatible scanner that uses ultrasound to determine whether a person has reached full legal age.
08/11/2017Major surgeries in the abdominal region often result in kidney injury in patients. Meanwhile, the clinical manifestations don't present until one or two days after the procedure. This causes physicians to lose valuable time to treat patients. The University Hospital Regensburg has researched a new concept for the treatment of kidney injuries for several years.
23/10/2017According to the WHO, 300 million people throughout the world are affected by lymphedema. This condition occurs when fluid that flows between cells is no longer transported back into the blood circulation and accumulates in the skin. Triggers can be surgeries, injuries or genetic defects for example. A new microscopy technique could now also indicate the causes.
09/10/2017Whole-body electromyostimulation (WB-EMS) promises time-efficient muscle strength training that has positive effects after just a few sessions per week. Its objective is a fast increase in muscle mass and reduction of body fat. Can WB-EMS training replace conventional strength and endurance training? And can it help to prevent diseases or pain?
02/10/2017If you are interested in laboratory medicine and come to the MEDICA 2017, you will quickly notice that Exhibition Halls 1 and 2 were demolished. A new state-of-the art hall is meant to take their place. Until then, exhibitors from the field of laboratory medicine will be showcased at their temporary new location in the lightweight hall structures 3a and 18 on the fairgrounds.
22/09/2017Many people all over the world suffer from myopia, also known as nearsightedness. A severe elongation of the eyeball is the cause behind it. If it continues to progress, it ultimately leads to complete loss of vision. Now an innovative medical device intends to stop this progression in the future.
01/09/2017There are many causes of myocarditis or inflammation of the heart muscle. Oftentimes, the culprits are viruses or bacteria and sometimes even an acute heart attack. Regardless of the cause, it creates a challenge for cardiologists: a diagnosis tends to be only nonspecific without a biopsy. A cardiac MRI and molecular imaging promise to provide assistance.
22/08/2017Physics has always supported medical science, especially when it comes to practical implementation. Now physicists and health professionals join in collaborative research at an interdisciplinary Center in Erlangen and incorporate fundamental principles of theoretical physics in their studies of diseases.
08/08/2017For centuries, scientific research has succeeded by chronicling experiments with pinpoint accuracy. Yet despite all the progress in the actual laboratory, recording is often still done manually, in notebooks, logs or computer systems for instance. In the future, a gesture recognition system could perform this task for scientists.
01/08/2017An increasing percentage of the world population suffers from chronic inflammatory disorders of the respiratory system. Acute attacks often lead to a worsening of the disease and considerably reduce the patient’s lung volume. Nine institutes of a research alliance under the Leibniz Institute umbrella are working on technologies designed to predict and thus prevent exacerbations.
01/08/2017Many therapeutic drugs are very powerful, but they are also very toxic at the same time. Thus, they have to be measured regularly, again and again, so that an adjustment of the individual drug dosage can be made. Until now, the "normal" way was to take the blood sample, send it to a central laboratory and get the results after some days. A new point-of-care test can measure it in 15 minutes.
22/06/2017The doctor's profession is exhausting and involves many different activities. For a long time, there have been discussions about how doctors can be supported by other specialists. One solution: help from so-called physician assistants.
01/06/2017After a stroke or as a result of aging, there are many situations when people are impaired in their walking ability and rely on a personal assistant or auxiliary aids and services. The XoSoft Project offers a solution: a soft exoskeleton that can be worn like a pair of leggings and stiffens or softens, depending on the situation.
08/05/2017How can emergency room associates continue to educate themselves in a fast manner and without bureaucratic hurdles? The A.L.I.N.A Project, which gives associates new tools with special assistance services and learning environments, delivers the solution. We spoke with Prof. Sabine Blaschke at the University Hospital Göttingen about these tools and how they work.
02/05/2017India is a land of contradictions. On the one hand, it has densely populated cities with state of the art technology. On the other hand, two-thirds of the population still live under challenging hygienic and financial conditions in the rural areas. Despite these conditions or perhaps because of them, more and more medical technology companies from all over the world are interested in this market.
02/05/2017When it comes to the production and development of tech products, many people immediately think of Germany, Japan, the U.S. or Taiwan. What’s often unknown is that an emerging market like India also offers great potential. After all, the country has a large number of experts and just as much technical knowledge at its disposal.
03/04/2017Instant treatment is absolute vital for patients developing sepsis. Providing a specific therapy early on is key. To manage this the pathogenic organisms need to be identified accurately. But a fungal sepsis can still be a hard nut to crack.
03/04/2017Many aspects are uniformly regulated in Europe, however, hospital hygiene and MRSA prevention, for example, are not. The Netherlands plays a pioneering role in the fight against hospital-acquired infections. The country is an often-cited role model. But can other countries simply adopt the same system? And what makes it so different? MEDICA asked expert Prof. Alexander W. Friedrich.
03/04/2017The laboratory is one of the most important and pivotal bastions in patient care. In the laboratory, acute, chronic and genetic diseases are diagnosed, the progression of diseases such as diabetes is regularly checked or specialists look for biomarkers to adapt cancer therapies.
01/03/2017In the "KDI – Clinical Data Intelligence Project", researchers are trying to consolidate various types of data to make them useable and useful to both medical professionals and scientists. This is a tremendous undertaking, considering the data volumes from different sources. In this conversation with MEDICA, Dr. Martin Sedlmayr explains the project setup.
01/02/2017Using stents to treat glaucoma is not a new procedure but they have not been implanted into patients on a regular basis until only recently. But this is about to change, which is why MEDICA.de asked what these glaucoma mini-stents are able to do and who may be a good candidate for them. Professor Norbert Pfeiffer answered our questions.
01/02/2017Achromatopsia is a rare hereditary visual disorder. Along with total color blindness, patients most notably suffer from reduced visual acuity and increased sensitivity to light and glare.
02/01/2017Treatments for children need to be different from treatment for adults – this also applies in oncology. Having said that, children do not just need new and different treatment concepts that still necessitate research. They also require the support from their families, who need to be nearby during treatment.
21/12/2016Within the scope of the VIRUSCAN project that is funded by the Horizon 2020 Research and Innovation Program of the European Union, Dr. Charlotte Uetrecht from Hamburg/Germany investigates individual viruses to be able to later identify them on a nanospring structure. MEDICA.de wanted to know: how does this work?
08/12/2016Watching millions of neurons in the brain interacting with each other – for a long time this was possible only to a limited extent. The current techniques can visualize only superficial layers or the imaging they use is too slow. But now, Prof Daniel Razansky and his team have found a new method to visualize the brain activity – by using optoacoustics.
22/11/2016It happens about 1,800 times per year: after a sporting or traffic-related accident, a person’s spinal cord is injured to where nerve tracts are severed and he/she becomes paralyzed. Researchers now want to develop software that measures the brain signals of paralyzed patients and sends out electrical impulses via a system to stimulate muscles, causing them to move again.
02/11/2016Call systems: every hospital patient is familiar with them, but hardly anyone gives any thought to how they work. And yet they fulfill an important function because in an emergency, they "call" for help. Just think what might happen if they didn’t work. That is why they are subject to stringent safety regulations. We spoke with D.Eng. Matthias Rychetsky, who is familiar with call systems.
04/10/2016So far, avatars could only be found in computer games. But if researchers of the EU-wide www.myhealthavatar.eu project have their way, this could soon change.
04/10/2016Chronic inflammatory bowel diseases like Crohn’s disease and ulcerative colitis increasingly develop at a younger age and affect patients for life. Regular check-ups need to occur every two to three months. Now, a specially designed app intends to provide relief.
01/09/2016Patients take center stage during surgery. Their treatment should be as gentle and effective as possible, which is why there is a trend towards minimally invasive surgery (MIS). But minimal procedures require better supporting technologies. The hybrid operating room combines surgery and imaging systems and increasingly replaces conventional open surgery approaches with MIS.
08/08/2016What happens when stem cells differentiate? What molecular characteristics do they have? Questions that can now be easier answered with the help of a new open-source software. We spoke with Prof. Fabian Theis at the Helmholtz Center Munich, who participated in the software development.
01/06/2016Some hospitals have long banned the status symbol of physicians – the white coat. Research has shown that especially the sleeves were contaminated with various types of bacteria. But it’s not just lab coats that can spread germs in healthcare settings. This field uses a variety of different textiles. Wouldn’t it, therefore, make sense to apply antimicrobial finishes?
02/05/2016Heart failure or cardiac insufficiency presents an extra strain on patients because it severally limits everyday performance and deprives them of energy. Due to their intense need for movement, children are particularly strongly affected. However, the disease is frequently not detected until the physical performance is already declining. An early diagnosis could prevent this.
22/04/2016How can you print ceramics, what purpose do they have and how benefits medical technology? Answers provides Dr. Tassilo Moritz from Fraunhofer Institute for Ceramic Technologies and Systems IKTS.
04/01/2016Most Europeans think it was a long time ago, but the residents of West Africa clearly feel the consequences of the Ebola epidemic that broke out in December 2013 and still continues today. So far, approximately 11,300 people have died as a result of the outbreak; more than 28,000 contracted the disease.
01/12/2015If you could stimulate brain cells to grow in a specific direction, you would probably be able to achieve a significant improvement in the health of patients suffering from Parkinson’s disease. This is why the MAGNEURON project focuses on this approach. The EU is funding the project with approximately 3.5 million Euros.
02/11/2015Minimally invasive surgeries are gentler on the patient but have one distinct disadvantage for the surgeon: he is not able to interact directly with the operating field. Sometimes he misses impressions that are very important to the success of the intervention. The MiroSurge robot for surgical applications which transmits feedback to the surgeon can help.
01/10/2015Semiconductor nanoparticles for biomedical applications have been researched for some time now. Not only are they millionths of a millimeter in size, they also offer great potential for cancer diagnostics and therapy, so-called theranostics. They enter cells, are activated by ultrasonic radiation and destroy the cells using the generated vibration.
01/10/2015It is a portmanteau, a mixture of two words. This way it saves us time and trouble while speaking because the human speech apparatus is lazy. And it describes a mixture of procedures: the combination of two procedures that would normally be separate in medicine. We are talking about theranostics.
01/09/2015They can be seen everywhere: at the wrists, in the ear, clipped to the belt. Wearables are small technical assistants who are built to collect and partially also to analyze data. Some of them collect measurable health data, others "only" count their user’s steps or measure the surrounding UV radiation. The fact is, however, that wearables are en vogue and are used for many different cases.
24/08/2015The term big data is complex. On one hand, it describes the amount of data itself while characterizing the technology required to collect and analyze the data on the other. The fact is big data is essential in medicine. Data-supported models not only assist in promoting medical research, they also make it easier to reach treatment decisions.
03/08/2015Malignant tumors can be fought with X-rays – usually with radiation therapy from outside the body. Nuclear medicine physicians can also accomplish this inside the body with radioactive materials, called radiopharmaceuticals. They also offer big benefits for clinical diagnostics as long as a specific target can be assigned to them.
08/07/2015Electronic health records, telemedicine, cloud computing and big data: questions about data protection appear everywhere in digitized health care. Yet what do things look like far away from application at the foundations of medicine? Can patient data and personal rights in research be protected when several centers and numerous researchers participate in studies?
01/07/2015When measuring myocardial activity, it is important for the skin to always stay moist under the electrodes of the ECG. Only then can data be consistently transferred. Athletes have an easier time with this: they are used to sweating. This is a lot harder for older patients.
08/06/2015Replicating the human organism in a mini format – researchers at the Fraunhofer IWS braved this challenge. They developed a compact system where different physical processes can be imitated on a chip. It is also possible to copy cardiac and pulmonary functions.
01/06/2015When cancer is diagnosed, the terms tumor markers or biomarkers keep popping up. They describe characteristics that are not found in healthy persons. The classic tumor markers can be easily detected in blood samples or other body fluids. Other analysis methods require more effort. Yet they all share one thing in common: biomarkers indicate a potential tumor.
01/06/2015A tumor is as unique as the person who is affected by it. For a long time, it was assumed this would make treatment more difficult since cancer drugs are not able to be one hundred percent effective in targeting the affected cells. In this interview with MEDICA.de, Professor Ugur Sahin explains why it is precisely these individual mutations that make him hopeful for a new type of therapy.
04/05/2015Since the end of April 2015, the long-awaited evaluation report on the skin cancer screening programs offered by German health insurance providers is now finally available. We spoke with Dr. Ralph von Kiedrowski, Board Member of the German Dermatologist Association (German: Berufsverband Deutscher Dermatologen) on what the screening can accomplish and his take on the G-BA report.
23/03/2015Does a patient benefit from treatment or not? How many patients are being treated as a result of damaged cartilage in the knee joint? What intervention is performed most frequently? These and other questions are meant to be answered in the future with the help of a new Cartilage Registry, which was created by the German Society for Orthopedics and Trauma Surgery.
02/03/2015How should a hospital best respond to an emergency and which types of crises should it be prepared for? We spoke with Professor Ronald Glasberg at the SRH Hochschule Berlin on this subject.
23/02/2015An 80-year-old female patient needs a new aortic valve replacement. Since the old one is severally calcified, the leaflets no longer open properly. Due to various factors, the patient is considered inoperable. Nevertheless, to make surgery possible for her, specialists at the Heart and Diabetes Center NRW in Germany have prepared the intervention based on an exact 3D heart replica.
02/02/2015Only projects with a solid foundation are successful in the long run. This is also true for science. Biobanks are the most important component of this foundation when it comes to fundamental biomedical research: Only high quality tissue samples that are stored there make conclusive research possible - for example in search of the causes of tumorigenesis.
05/01/2015T-cells are the guardians of our immune system. When they show changes, it can lead to severe inflammatory responses in the body. It is believed that the T-cells in persons who are affected by inflammatory bowel disease don’t work properly. Two proteins that can be found on activated T-cells and that interact with each other are now being analyzed.
08/12/2014Comparative research models are indispensable in wound healing research to evaluate new treatments of chronic wounds. Consequently, studies need to exhibit equivalent basic prerequisites and be conducted on similar wounds. This is why a team of researchers is working on an automated process to place standardized wounds in skin models.
01/12/2014How does a physician handle a patient, who wants to die and what rights do I actually have as a patient? Legal practitioners do not automatically answer these and other questions. We talked about this subject with MD-PhD Ralf Jox from the Institute of Ethics, History and Theory of Medicine at the Ludwig Maximilians University of Munich, Germany.
24/11/2014How do diseases of civilization develop and can they be prevented when you know triggering factors? A new National Cohort should deliver answers in the coming years. The Leipzig Research Center for Civilization Diseases is involved in this study. We spoke with Dr. Kerstin Wirkner, who is going to co-supervise the study in Leipzig.
03/11/2014As an imaging procedure, magnetic resonance tomography has become essential in clinical practice, since it can easily make organs and tissue visible. However, until now abnormal cancer cells or small centers of inflammation remained almost invisible. Now cell biologists from Berlin, Germany, have succeeded in fixing this problem with xenon magnetic resonance imaging.
03/11/2014The treatment of chronic wounds is extremely problematic. Chronic wounds can take months or years to heal and some even never heal resulting in over 100.000 amputations taking place annually in the US alone. A new technology from Iceland, that is based on fish skin and is already used clinically, allows for improved healing of chronic and burn wounds.
01/10/2014On November 10, 2014, astronaut Alexander Gerst will return to Earth from the International Space Station (ISS). He is not just anxiously expected by his family, but also by Dr. Anna-Maria Liphardt from the Institute of Biomechanics and Orthopedics at the German Sport University Cologne
22/09/2014They are not just “a girl's best friend“, but are also important helpers in medicine: diamonds. Yet the latter are so tiny that they are not visible to the naked eye. Dr. Patrick Happel at the Ruhr University Bochum in Germany studies so-called nanodiamonds. Someday soon, they are supposed to help in significantly improving medical imaging.
01/09/2014The public only notices diseases when celebrities become patients: in the spring of 2014, Formula One driver Michael Schumacher fell into a coma for several months as the result of a head injury caused by a skiing accident. These types of accidents show how delicate the brain responds to injuries. Brain stimulation could possibly support the rehabilitation of vegetative patients.
01/09/2014When very young children already need to be in the operating room, it’s not just the parents that are concerned. This type of situation is a special challenge for the entire operating team, because children are always very special patients - especially since they are not just simply small grown-ups!
08/08/2014A magnesium implant will soon be available to help patients, who exhibit damage in the high-pressure area of the heart. The implant protects a tissue matrix where new cells that replace the affected tissue are meant to grow. The implant itself is supposed to completely dissolve after several months. MEDICA.de spoke with D. Eng. Thomas Hassel about this exciting project.
01/07/2014In patients with Parkinson's, neural cells in the brain die off that produce the neurotransmitter dopamine. Certain physical symptoms that can indicate the disease follow years later. But a reliable diagnosis can only be made through examination of the brain after the patient's death, and not during his lifetime.
01/07/2014The not so popular “love handles“ could revolutionize medicine in the near future. In cooperation with the University of Rostock (Professor Hermann Seitz), the human med AG Company currently seeks to develop a device that is able to gently remove adipose tissue during surgery and subsequently isolate stem cells.
10/06/2014The German Technician Health Insurance (German: Techniker Krankenkasse) conducted a study on the Topic “Phone coaching helps seriously ill patients and saves money“. We spoke with Günter van Aalst about the interesting findings.
02/06/2014When are sports healthy, how often should you engage in sports and what effect do sports have on the body – over the past few decades, there were always different answers to these questions. Many studies that were conducted in the past however confirm the assumption that sports and exercise always support health, even if someone is already sick.
02/05/2014Staying active and mobile when you are old – who doesn’t want that? People suffering from dementia can often only dream about that. The fear of not finding your way back home or not getting any help in an emergency severally restricts many affected people in the way they live their lives. Yet there are many people, who could still independently participate in life despite mild dementia.
22/04/2014The International Space Station ISS is not only the largest artificial object in space. It is also a laboratory for physicists, chemists, biologists and physicians and orbits earth at 28.000 kilometers per hour at an altitude of 400 kilometers. Thanks to this location, the ISS could one day make an important contribution to regenerative medicine.
08/04/2014Dr. Walter Kromm, Master of Public Health, is not just a general practitioner, but also a health advisor for management professionals. During his many years of practical experience, he kept realizing how important employee health is for the health of an entire company.
24/03/2014He is kind of a "Bones" McCoy, since he keeps astronauts fit: Dr. Simon Evetts leads the Medical Projects and Technology team within the Medical Support Office of the European Astronauts Centre in Cologne, Germany. MEDICA.de talked to him about sports in universe, space technology and the benefits for us earthlings.
10/03/2014Children are not just small adults and they cannot be treated as such. Physicians have recognized this but manufacturers of medical devices have a hard time here: the market for pediatric medical devices is very small and researchers have difficulties to turn their ideas into commercially successful products.
04/03/2014Continuing education is an integral part of the medical profession, because research continuously delivers new findings that sooner or later make their way into patient treatments. How does an event need to be organized to provide the highest level of benefit for the participants? MEDICA.de spoke with Eva Ningel, Managing Director for beta seminare bonn berlin GmbH (bsbb).
24/02/2014Magnetic resonance imaging (MRI) is a well-established procedure in clinical diagnostics. It creates a signal with millions of nuclear spins, which in turn is converted into images. Very large magnets are being used to align the nuclear spins. Researchers at the University Medical Center Freiburg study a new method that can do without expensive magnets.
10/02/2014Prof. Joachim Heberle from the Free University of Berlin wants to make the smallest protein structures visible under the microscope. He wants to accomplish this with an infrared microscope, originating in the field of physics. He told MEDICA.de which technology is behind all this and what he also wants to examine with it in the future.
03/02/2014Radiologists usually do their work after oncologists when it comes to cancer treatment. Yet modern radiology also provides treatments at this point. MEDICA.de spoke with Professor Stefan Schönberg, Director of the Institute of Clinical Radiology and Nuclear Medicine at the University Medical Center Mannheim, Germany, about the use of a new computer tomograph and its benefits for patients.
22/01/2014It guards the body but can become its enemy: the immune system defends us from intruding pathogens; it is also able to cause severe diseases if it falsely recognizes the body itself as a threat. Molecular receptors in the whole body enable the immune system to “sense” what happens within.
15/01/2014In Western civilization, equality of women and men has been a topic for many years and is already being successfully implemented in many areas, even if many obstacles still need to be overcome – the introduction of quotas for women in boardrooms, just to mention one of them.
08/01/2014Heart diseases can be triggered by special viruses that affect the cardiac muscle. Preventive drugs could definitely be developed – if the virus does not mutate.
06/01/2014Whether a surgical suture is better applied manually or with a surgical stapler can be determined through trial and error. Determining which method guarantees patient safety best should also not just be based on a surgeon’s experience. Controlled studies are the method of choice to assess both well-proven and new techniques in the operating room.
06/01/2014Even medical risk products are not always tested as thoroughly as would be necessary – be it because of criminal energy, lack of know-how or financial reasons. A revision of clinical trial procedures could not only fix loop holes and methodological flaws. Products and methods could also be brought into general medical care more quickly under new rules.