The accumulation of mutations in the human genome is at the origin of cancers, as well as the development of resistance to treatments. The Cyclin E and Myc genes are active in the control of cell division. When they are mutated, for example in response to a carcinogen, these genes induce cells to start replicating their DNA prematurely during the cell cycle.
A newly-discovered hereditary mutation is responsible for an increased production of erythropoietin (EPO) in the blood. This mutation causes a messenger RNA (mRNA) that is not normally involved in the formation of proteins to be reprogrammed so that it produces EPO, thus abnormally increasing the number of red blood cells.
Working with cells grown in the lab, Johns Hopkins researchers have identified a biochemical pathway that allows a structure within cells, called the Golgi apparatus, to combat stress caused by free radicals and oxidants. The research team showed that this pathway can be activated by a drug called monensin, which is commonly used as an antibiotic in animal feed.
Cardiovascular disease patients have lower levels of an important family of protective molecules in their blood in the morning, which could be increasing their risk of blood clots and heart attacks at those times, according to early research led by Queen Mary University of London.
Brown adipose tissue has played a key role in prevention research since its presence was first documented in adults. However, there was no non-invasive method of measuring its heat generation. A team at the Technical University Munich (TUM) and the Helmholtz Zentrum München has now succeeded in making the activity of brown adipose tissue visible without injecting substances.
A clinical study coordinated by the French National Research Institute for Sustainable Development and Chiang Mai University with their Thai, American, and French partners, strengthens the case for a new strategy to prevent mother-to-child transmission of the hepatitis B virus.
A discovery led by scientists at the University of Alberta and McGill University is providing hope of a new therapeutic target in Multiple Sclerosis (MS) patients, which could one day be used to prevent the symptoms and progression of the disease.
About 1 in 2,500 people have a degenerative nerve disease called Charcot-Marie-Tooth (CMT). The disease is typically diagnosed in children, who can lose their ability to walk and use their hands for fine motor skills. There is no cure – yet.
Scientists on the Norwich Research Park have discovered a key mechanism by which gut bacteria colonise and adhere to their specific hosts. The finding may lead to new, improved probiotics with optimised abilities to colonise our gut and battle infections by forming strong associations with the host as biofilms.
FocalSpec, the Finnish expert in high-precision quality control devices, will launch their first 3D imaging and metrology system UULA at MEDICA Trade Fair in Düsseldorf, Germany. UULA can be used both...
Ginolis, a global supplier of production automation and dispensing solutions, today announced a distributor agreement with Darwin Microfluidics, an online supplier of microfluidic kits, products and...
IMMS demonstrates prototype at MEDICA, Nov 13th – 16th, Hall 3/G60 13th November 2017. At the MEDCIA trade fair in Düsseldorf, Germany, IMMS presents via live-demo a passive RFID microelectronic chip...
Jena, November 13, 2017 - The success of FiLaC® therapy for the particularly painless and sphincter-friendly removal of anal fistulas from biolitec®, the technology leader in minimally invasive laser...
EFORE Plc, an international company which designs and manufactures custom and standard AC/DC power supplies and power systems, is pleased to announce it will showcase several new Medical Grade Power...
Image: A large stone is blocking a path that leads through a green meadow; Copyright: panthermedia.net/Brigitte Götz
These days, many groups make various demands of medical device developers: manufacturers, users, patients and government agencies. Given all of these interests and concerns, the developers face many challenges. In this interview, we put some of them under the microscope and examine how they can be sidestepped or entirely avoided.
Image: Young female radiologist is looking at pictures of the head and takes some notes; Copyright: firstname.lastname@example.org
Automation makes work life easier in many ways but is it also a solution for analyzing medical images? Is a computer actually reliable enough to assist in the medical decision making process? Researchers in Landshut examine how machine learning algorithms can work more reliably and support radiologists.
Image: Young female student is sitting between shelves on the floor of a library and reads; Copyright: panthermedia.net/Brock Jones
Research does not always occur in laboratory settings. As part of citizen science, citizens collect data and make it available for research projects. Now, this approach is also adopted in medicine by way of patient science: in a new project, patients take part in cystic fibrosis research. The goal is to improve the lives of those who are affected by this chronic disease.