29/09/2016A multi-institutional academic and industry research team led by investigators from Massachusetts General Hospital (MGH) and the Harvard Stem Cell Institute has identified a promising new approach to the treatment of acute myeloid leukemia (AML).
16/09/2016Researchers at the National Cancer Institute in the USA and the Babraham Institute, UK, have discovered how a mineral ion leaked from tumour tissue as it dies acts to stop the work of anti-tumour immune cells. This discovery provides a new approach in the development of treatments to engage the immune system in the fight against cancer.
16/09/2016The following factors facilitate the formation of putatively toxic structures in the neuronal nuclei of Alzheimer's patients. Spherical structures in the nucleus of nerve cells, so-called nuclear spheres, are suspected to trigger Alzheimer's disease.
15/09/2016Researchers at VIB and Ghent University have discovered an important mechanism of sepsis, an overreaction of the body’s immune system to an infection. In this condition, the brain is unable to curb an inflammatory response, causing organ failure or ‘septic shock’.
15/09/2016Cells in the immune system of patients with multiple sclerosis behave differently from those of healthy individuals. Researchers at Linköping University in Sweden have exploited this difference to develop a method that can predict disease activity in multiple sclerosis.
14/09/2016Researchers in Singapore have developed a new protein that can alter DNA in living cells with much higher precision than current methods.
12/09/2016Individual cells within a tumor are not all the same. This may sound like a modern medical truism, but it wasn't very long ago that oncologists assumed that taking a single biopsy from a patient's tumor would be an accurate reflection of the physiological and genetic make-up of the entire mass.
09/09/2016Researchers at the University of Adelaide have shown how a complex mix of plant compounds derived from ancient clinical practice in China – a Traditional Chinese Medicine – works to kill cancer cells.
08/09/2016Researchers discover a signalling pathway that enables cells to reach their destinations through repulsion.
31/08/2016In adults with a house dust mite allergy, a cascade of inflammatory signals on the surface of the airways leads to airway remodeling. This process cannot be influenced by standard cortisone therapy. Researchers at Helmholtz Zentrum München and the Technical University of Munich have reported these findings.
29/08/2016Cytocompatibility studies of organic light-emitting diodes (OLEDs) have been carried out on cell cultures for the first time at the Fraunhofer Institute for Organic Electronics, Electron Beam and Plasma Technology FEP to test how well OLEDs are tolerated by cells.
26/08/2016Boosting levels of a specific protein in the brain alleviates hallmark features of Alzheimer's disease in a mouse model of the disorder, according to new research published online in "Scientific Reports".
25/08/2016Especially in late summer, apprehension about wasp stings increases amongst allergy sufferers. So-called hyposensibilisation therapy can help, but it is linked to a heavy burden on patients and health insurers. Researchers at the Helmholtz Zentrum München and the Technical University Munich have now presented a method in the journal "Allergy", which facilitates a personalised procedure.
24/08/2016A discovery in the field of biomaterials may open new frontiers in stem and cancer cell manipulation and associated advanced therapy development. Novel scaffolds are shown enabling cells to behave in a different but controlled way in vitro due to the presence of aligned, self-assembled ceramic nanofibers of an ultra-high anisotropy ratio augmented into graphene shells.
23/08/2016Combining ultrasound energy and microbubbles to poke holes in cells may prove to be a new tool in the fight against cardiovascular disease and cancer, according to researchers from the University of Pittsburgh and UPMC. A study on this gene therapy approach, called sonoporation, is published in the Proceedings of the National Academy of Sciences (PNAS).
22/08/2016Genetically analysing lesions in the food pipe could provide an early and accurate test for oesophageal cancer, according to research led by Queen Mary University of London (QMUL), Academic Medical Center in Amsterdam and Arizona State University.
09/08/2016Advanced economy nations led by Ireland, Singapore, Australia, Germany, Italy, Japan, and the United States have the highest per capita number of clinics engaging in direct-to-consumer marketing of stem cell therapies, according to the world's largest-ever study of such clinics.
05/08/2016Researchers has developed a computer model that will aid in the design of nanocarriers, microscopic structures used to guide drugs to their targets in the body. The model better accounts for how the surfaces of different types of cells undulate due to thermal fluctuations, informing features of the nanocarriers that will help them stick to cells long enough to deliver their payloads.
02/08/2016It may be clammy and inconvenient, but human sweat has at least one positive characteristic - it can give insight to what is happening inside your body.
22/07/2016Using a robust model for Parkinson's disease, University of Alabama at Birmingham researchers and colleagues have discovered an interaction in neurons that contributes to Parkinson's disease, and they have shown that drugs now under development may block the process.
22/07/2016A study led by researchers at Universitat Jaume I de Castellón has identified one of the genetic causes underlying the higher rate of melanoma in men. The results have been published in Biology of Sex Differences.
22/07/2016The study, led by IRB Barcelona and published in Nature Communications will help research into regenerative medicine and potentially also help understand neurodegenerative diseases such as Alzheimer’s.
21/07/2016Johns Hopkins University biologists have found that a protein that plays a key role in the lives of stem cells can bolster the growth of damaged muscle tissue, a step that could potentially contribute to treatments for muscle degeneration caused by old age and diseases such as muscular dystrophy.
21/07/2016The World Federation of Neurology (WFN) invites the people to observe the World Brain Day for the third time in 2016. This year’s motto is “The ageing brain”. The focus lies on prevention of and dealing with the neurological diseases stroke, Alzheimer’s disease and Parkinson’s disease, since the risk to fall ill with them increases with age.
14/07/2016Researchers at MIT's research center in Singapore have developed a new microfluidic device that tests the effects of electric fields on cancer cells. They observed that a range of low-intensity, middle-frequency electric fields effectively stopped breast and lung cancer cells from growing and spreading, while having no adverse effect on neighboring healthy cells.
07/07/2016In colorectal cancer, the presence of invasive tumor cells at the advancing edge of the tumor can provide valuable information on prognosis. Initiated by the Colorectal Cancer Research Group at the Institute of Pathology, University of Bern, a consensus conference was held to determine how this phenomenon should best be put into practice.