02/12/2016An optical fiber probe can distinguish cancer tissue and normal tissue at the margins of a tumor being excised, in real time, by detecting the difference in pH between the two types of tissue. This has the potential to help surgeons avoid removing too much healthy tissue during surgery and also avoid performing additional surgeries later to remove any cancer tissue left behind.
28/11/2016As Zika spreads throughout the world, the call for rapid development of therapeutics to treat Zika rings loud and clear. Taking a step further in identifying a possible therapeutic candidate, a team of researchers have discovered the mechanism by which C10, a human antibody previously identified to react with the Dengue virus, prevents Zika infection at a cellular level.
24/11/2016A team of Norwegian, French and Australian researchers is the first in the world to succeed in quantifying the effects of radiation on individual cancer cells. This means that radiation therapies can now be tailored to individual tumors and thus be more effective.
15/11/2016Researchers from MIT and Harvard Medical School have developed a biocompatible and highly stretchable optical fiber made from hydrogel — an elastic, rubbery material composed mostly of water. The fiber, which is as bendable as a rope of licorice, may one day be implanted in the body to deliver therapeutic pulses of light or light up at the first sign of disease.
04/11/2016A team headed by scientists from the Department of Biosystems at ETH Zurich in Basel has developed a cell culture technology platform for testing interactions between chemical and pharmaceutical compounds and three-dimensional body tissue samples.
04/11/2016Fresh insights into a life-threatening lung condition triggered by blood poisoning could signal a new approach to treating the disease, researchers found. Scientists have found that a drug, which targets key immune cells, could help to curb excessive inflammation in the lungs that is linked to the condition.
03/11/2016Researchers centered at Osaka University identify molecule specifically expressed on one of the first cell populations to emerge as a precursor of the heart in embryos, which enables the cells to be isolated and studied, and potentially transplanted as a treatment for heart failure.
03/11/2016Inflammatory bowel disease (IBD) is a complex condition that requires a lifetime of care and increases a person's cancer risk. But its origins are still a mystery. Now, a team of researchers have created a new culture model of the human intestine where living tissue from a patient biopsy can be preserved and studied for days.
01/11/2016The epigenetic enzyme Lsd1 plays an important role in maintaining brown fat tissue.
31/10/2016Research investigating how DNA from a virus millions of years old may affect the development of nerve tumours, has been awarded funding.
31/10/2016The distinct structures of toxic protein aggregates that form in degenerating brains determine which type of dementia will occur, which regions of brain will be affected, and how quickly the disease will spread, according to a study from the Peter O’Donnell Jr. Brain Institute.
20/10/2016Researchers delivered human stem cells seeded in biological sutures to the damaged heart muscles of rats following induced acute myocardial infarction and assessed the effects on cardiac function one week later.
19/10/2016Led by Lehigh University professor, the team utilized biomolecular systems simulation to reveal the membrane properties of 21 distinct Lipid A types from 12 Gram-negative bacterial species--a crucial step toward new antibiotic drug development.
18/10/2016Several peptides have an antibacterial effect - but they are broken down in the human body too quickly to exert this effect. Empa researchers have now succeeded in encasing peptides in a protective coat, which could prolong their life in the human body. This is an important breakthrough because peptides are considered to be a possible solution in the fight against antibiotic-resistant bacteria.
17/10/2016A new imaging technique is under development with the aim of detecting and characterizing early cancerous changes in the gastrointestinal (GI) tract
17/10/2016New human pluripotent stem cells lines are derived from individuals of the Brazilian population - with European, African and Native American genomic ancestry; they can be used for testing drug toxicity and for studying differential drug response
05/10/2016The fight against cancer is a marathon, fought step by step, inch by inch. While breakthroughs may be rare, a new study from the Faculty of Medicine & Dentistry is giving greater insight into the growth of cancer cells and bringing researchers one step closer to the finish line.
29/09/2016A multi-institutional academic and industry research team led by investigators from Massachusetts General Hospital (MGH) and the Harvard Stem Cell Institute has identified a promising new approach to the treatment of acute myeloid leukemia (AML).
16/09/2016Researchers at the National Cancer Institute in the USA and the Babraham Institute, UK, have discovered how a mineral ion leaked from tumour tissue as it dies acts to stop the work of anti-tumour immune cells. This discovery provides a new approach in the development of treatments to engage the immune system in the fight against cancer.
16/09/2016The following factors facilitate the formation of putatively toxic structures in the neuronal nuclei of Alzheimer's patients. Spherical structures in the nucleus of nerve cells, so-called nuclear spheres, are suspected to trigger Alzheimer's disease.
15/09/2016Researchers at VIB and Ghent University have discovered an important mechanism of sepsis, an overreaction of the body’s immune system to an infection. In this condition, the brain is unable to curb an inflammatory response, causing organ failure or ‘septic shock’.
15/09/2016Cells in the immune system of patients with multiple sclerosis behave differently from those of healthy individuals. Researchers at Linköping University in Sweden have exploited this difference to develop a method that can predict disease activity in multiple sclerosis.
14/09/2016Researchers in Singapore have developed a new protein that can alter DNA in living cells with much higher precision than current methods.
12/09/2016Individual cells within a tumor are not all the same. This may sound like a modern medical truism, but it wasn't very long ago that oncologists assumed that taking a single biopsy from a patient's tumor would be an accurate reflection of the physiological and genetic make-up of the entire mass.
09/09/2016Researchers at the University of Adelaide have shown how a complex mix of plant compounds derived from ancient clinical practice in China – a Traditional Chinese Medicine – works to kill cancer cells.