Photo: Left to right, green fluorescence shows damaged area shrinking over time. Top row, eyes from normal mice. Other rows are eyes from three different mouse models of diabetes

Electric fields weaker in slow-healing diabetic wounds

17/06/2016

People with diabetes often suffer from wounds that are slow to heal and can lead to ulcers, gangrene and amputation. New research from an international group led by Min Zhao, professor of ophthalmology and of dermatology at the University of California, Davis, shows that, in animal models of diabetes, slow healing is associated with weaker electrical currents in wounds.
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Photo: Large metal device with a pink glowing window in the fron

Plasmasterilization: active ingredient cocktail to fight bacteria

01/06/2016

Until now, plasma, the fourth state of matter,was consideredfascinatingonly to astrophysicists and science fiction fans. But at this point, it also attracts the interest of medicine because plasma can have many uses in this field. In the future, plasma sterilization could become an important component of hospital hygiene-provided that the right device is being used.
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Photo: 3-D printed scaffold for a human jaw bone

3-D printed bone with just the right mix of ingredients

13/05/2016

To make a good framework for filling in missing bone, mix at least 30 percent pulverized natural bone with some special man-made plastic and create the needed shape with a 3-D printer. That is the recipe for success reported by researchers at The Johns Hopkins University in ACS Biomaterials Science & Engineering.
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Photo: Stent in human body

Safe or Not Safe? "The AB-DES has not gained market access in countries like Japan or the U.S."

01/05/2016

Antibody-coated, drug-eluting stents (AB-DES) feature an exterior coated with immunosuppressant drugs and an interior that is coated with antibodies to accelerate the adhesion of endothelial cells. In theory, this makes it possible to shorten the duration of therapy with blood thinners, which can mean relief for patients from an already difficult situation.
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Photo: Printer head over a glass sheet

Melt electrospinning writing: polymer fibers for tissue engineering

01/02/2016

Sometimes, soft tissue in our body needs to be replaced after surgery or an injury. But surgeons are not always able to take tissue from other body parts as a replacement. Then, they need to use implants. The production of soft implants that can constantly endure load and stress like our own tissue is a big challenge for research. Melt electrospinning writing can be a solution.
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Photo: Stents

Stents: Braiding versus cutting

22/05/2015

Braided stents are nothing new in medicine, but their manufacturing process is still time-consuming. This is why Professor Stefan Jockenhövel from the RWTH Aachen University and his team want to make machine production possible.
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Photo: device for standardized wounds

ARTcut: Standardized injury of skin models for wound healing research

08/12/2014

Comparative research models are indispensable in wound healing research to evaluate new treatments of chronic wounds. Consequently, studies need to exhibit equivalent basic prerequisites and be conducted on similar wounds. This is why a team of researchers is working on an automated process to place standardized wounds in skin models.
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Wound treatment with fish skin

03/11/2014

The treatment of chronic wounds is extremely problematic. Chronic wounds can take months or years to heal and some even never heal resulting in over 100.000 amputations taking place annually in the US alone. A new technology from Iceland, that is based on fish skin and is already used clinically, allows for improved healing of chronic and burn wounds.
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Cultured skin makes large-scale transplantations possible

01/07/2014

Large burns require skin grafting. Surgeons remove split-thickness skin grafts and apply them to the injured areas. Now skin that has been made in a laboratory is meant to help in covering burns as well as chronic wounds and thus promote the healing process. Researchers in Zurich have been working on this for more than 13 years.
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