Image: Graphic of a E. coli outer membrane; Copyright: Courtesy of Wonpil Im, Lehigh University

Scientists model outer membrane of 12 bacterial species to speed new drugs for 'bad bugs'


Led by Lehigh University professor, the team utilized biomolecular systems simulation to reveal the membrane properties of 21 distinct Lipid A types from 12 Gram-negative bacterial species--a crucial step toward new antibiotic drug development.
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Image: Young child next to a physician; Copyright:

Children: antibiotic exposure associated with food allergy risk


Antibiotic treatment within a child's first year of life may wipe out more than an unwanted infection: exposure to the drugs is associated with an increase in food allergy diagnosis, new research from the University of South Carolina suggests.
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Image: Peroxiredoxin Function; Copyright: Graphic courtesy of Oregon State University

Protein could open door to new class of antibiotics


Researchers have made the first-ever detailed, atomic-level images of a peroxiredoxin, which has revealed a peculiar characteristic of this protein and might form the foundation for a new approach to antibiotics.
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Image: Illustration of a bacteria; Copyright: Lehigh University

New immunotherapy to fight bacteria


An estimated 23,000 people in the U.S. die each year of antibiotic resistant bacterial infections, according to the Centers for Disease Control and Prevention (CDC). A UK government-commissioned review reports that such infections take 700,000 lives per year globally.
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Image: Bacteria are flowing to hospital's entrance; Copyright:

New maths to predict dangerous hospital epidemics


Mathematicians are now developing completely new statistical calculations on the world’s fastest computers in order to be able to predict how epidemics of dangerous hospital bacteria spread. Studying the entire genomes of bacteria has now thrown open entirely new possibilities for revealing their secrets. It is this genetic knowledge that scientists use to understand bacterial epidemics.
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Image: Young asian women is coughing in the street; Copyright: Cho Pan

Rapid bacterial infection test reduces antibiotic use


Researchers from the Oxford University Clinical Research Unit in Vietnam have shown that using a rapid (5-minute) test can reduce antibiotic misuse for respiratory infections. Cutting the number of unnecessary antibiotic prescriptions is a key way to prevent the spread of antibiotic-resistant infections.
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Photo: physicians at station

Gram-negative bacteria pose a major challenge for hospitals


Every day, people are admitted to the hospital, discharged or they visit patients. This large number of people increases the risk of bacteria transmission. Preventative measures such as short-sleeved uniforms and copper surfaces can help by improving hospital hygiene but they cannot replace the legal requirements for hygiene measures.
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Photo: Large metal device with a pink glowing window in the fron

Plasmasterilization: active ingredient cocktail to fight bacteria


Until now, plasma, the fourth state of matter,was consideredfascinatingonly to astrophysicists and science fiction fans. But at this point, it also attracts the interest of medicine because plasma can have many uses in this field. In the future, plasma sterilization could become an important component of hospital hygiene-provided that the right device is being used.
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Photo: Bacteria

Fecal microbiota transplantation: A stranger’s stool heals inflammatory bowel disease


It sounds strange: During fecal microbiota transplantation, the stool of a healthy donor is transferred into the intestines of a diseased patient to restore his or her damaged gut flora. This is an entirely normal process in the animal kingdom. Now the stool transplant has established itself as the standard for treating Clostridium difficile.
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