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Computational method identifies existing drugs with virus-fighting potential


A new, computer-based screening method could reveal the virus-fighting potential of drugs originally developed to treat other conditions, reports a study in PLOS Computational Biology.
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Protein in mosquito spit can keep Dengue virus in check


Mosquito saliva influences transmission of viruses to a bitten mammalian host. For example, it contains factors that dampen the host immune response and so facilitate infection. A study published in PLOS NTDs reports on a saliva protein with the opposite effect.
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New strategy identified for treating acute myeloid leukemia


A multi-institutional academic and industry research team led by investigators from Massachusetts General Hospital (MGH) and the Harvard Stem Cell Institute has identified a promising new approach to the treatment of acute myeloid leukemia (AML).
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Potentially harmful chemicals widespread in household dust


First-of-a-kind study reveals top 10 consumer product chemicals in dust with known or suspected health impacts.
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Image: Peroxiredoxin Function; Copyright: Graphic courtesy of Oregon State University

Protein could open door to new class of antibiotics


Researchers have made the first-ever detailed, atomic-level images of a peroxiredoxin, which has revealed a peculiar characteristic of this protein and might form the foundation for a new approach to antibiotics.
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A data-cleaning tool for building better prediction models


Big data sets are full of dirty data, and these outliers, typos and missing values can produce distorted models that lead to wrong conclusions and bad decisions, be it in healthcare or finance. With so much at stake, data cleaning should be easier.
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Critical protein shows promise for the treatment of Alzheimer's


The tidal wave approaches. In the coming decades, Alzheimer's disease is projected to exact a devastating economic and emotional toll on society, with patient numbers in the US alone expected to reach 13.5 million by mid-century at a projected cost of over a trillion dollars.
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Artificial intelligence expedites breast cancer risk prediction


Researchers at Houston Methodist have developed an artificial intelligence (AI) software that reliably interprets mammograms, assisting doctors with a quick and accurate prediction of breast cancer risk.
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Image: blood samples in test tubes; Copyright: USMC/Wikimedia Commons

People with type O blood more likely to die of cholera


People with blood type O often get more severely ill from cholera than people of other blood types. New research from Washington University School of Medicine in St. Louis may explain why.
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3-D-printed structures "remember" their shapes


Engineers from MIT and Singapore University of Technology and Design (SUTD) are using light to print three-dimensional structures that "remember" their original shapes.
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Lack of pharmacy access sends some patients back to the hospital


Hospital readmissions, a 17-billion-dollar annual problem, are higher in rural, remote or smaller communities that sometimes have significantly less access to pharmacies, according to a study published today that was one of the first to examine this issue.
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To beat hypertension, take the 'clinic' to the people


Eliminating racial disparities in the outcomes of programs to control blood pressure can be accomplished with a few one-on-one coaching sessions delivered by health professionals - but not if the program requires people to get to a clinic, according to results of a new Johns Hopkins Medicine study.
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New microfluidic chip replicates muscle-nerve connection


MIT engineers have developed a microfluidic device that replicates the neuromuscular junction - the vital connection where nerve meets muscle. The device, about the size of a U.S. quarter, contains a single muscle strip and a small set of motor neurons. Researchers can influence and observe the interactions between the two, within a realistic, three-dimensional matrix.
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Promising peer mentoring program for early career gero-nursing faculty


New models for providing mentorship to early career academics will become key to developing and maintaining an experienced faculty.
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Randomized penumbra 3-D trial of next generation stent retriever meets primary endpoints


The Society of NeuroInterventional Surgery's (SNIS) 13th Annual Meeting announced that the Penumbra 3D Trial successfully met the primary trial endpoints, demonstrating non-inferiority in safety and efficacy of Penumbra 3D Revascularization Device, when used with Penumbra System aspiration devices compared to Penumbra System aspiration devices alone.
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Graphic: Bridge connecting EU and Russia; Copyright: Kharchenko

Is the Russia crisis also a crisis for medical technology?


The Ukrainian political turmoil has been keeping the world in suspense since 2013. It has also caused growing tensions between Russia on the one hand and the U.S. and EU on the other hand. Both sides try to pressure each other with sanctions against individuals, international financial transactions and whole industry branches.
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Small companions: How wearables change our lives


They can be seen everywhere: at the wrists, in the ear, clipped to the belt. Wearables are small technical assistants who are built to collect and partially also to analyze data. Some of them collect measurable health data, others "only" count their user’s steps or measure the surrounding UV radiation. The fact is, however, that wearables are en vogue and are used for many different cases.
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Medical Devices Directive: Inspected and still not safe


The Medical Devices Directive defines what constitutes a medical device. At the same time, it inspects and monitors. However, scandals in the medical technology industry keep causing uncertainty. They rekindled debate over the safety and transparency of medical devices and also triggered changes on an international level. As a result, new laws are needed more than ever.
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Euthanasia – A Human Right?


Several weeks ago on November 1, 2014, 29-year-old Brittany Maynard, who suffered from terminal brain cancer, took drugs to end her life surrounded by her family. This was preceded by months of despair and anguish, but also by love and a lust for life as the young woman describes in several videos she recorded to fight for the right to die with dignity.
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Making Your Own End-of-Life Decisions: “All options of palliative care, pain management and continued life need to have been explained to the patient“


How does a physician handle a patient, who wants to die and what rights do I actually have as a patient? Legal practitioners do not automatically answer these and other questions. We talked about this subject with MD-PhD Ralf Jox from the Institute of Ethics, History and Theory of Medicine at the Ludwig Maximilians University of Munich, Germany.
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Photo: Dr. Anna-Maria Liphardt

Laboratory in Space: Hot on the Trails of Cartilage Degradation


On November 10, 2014, astronaut Alexander Gerst will return to Earth from the International Space Station (ISS). He is not just anxiously expected by his family, but also by Dr. Anna-Maria Liphardt from the Institute of Biomechanics and Orthopedics at the German Sport University Cologne
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Pediatric anesthesia: "I would object to a specialty medical training"


When very young children already need to be in the operating room, it’s not just the parents that are concerned. This type of situation is a special challenge for the entire operating team, because children are always very special patients - especially since they are not just simply small grown-ups!
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"Pediatric conditions often require pediatric-specific engineering"


Children are not just small adults and they cannot be treated as such. Physicians have recognized this but manufacturers of medical devices have a hard time here: the market for pediatric medical devices is very small and researchers have difficulties to turn their ideas into commercially successful products.
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